Difference between revisions of "Drug index"
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+ | <span id="BackToTop"></span> | ||
+ | <div class="noprint" style="background-color:LightGray; position:fixed; bottom:2%; right:0.25%; padding-left:5px; padding-right:5px; margin: 15px; opacity:0.8; border-style: solid; border-color:DarkGray; border-width: 1px"> | ||
+ | [[#top|Back to Top]] | ||
+ | </div> | ||
+ | =Guidelines= | ||
+ | '''Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any guideline published 5+ years ago to be for historical purposes, only.''' | ||
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'''Other [[#Interesting_and_Helpful_Links|interesting and helpful links]] can be found by clicking the link.''' | '''Other [[#Interesting_and_Helpful_Links|interesting and helpful links]] can be found by clicking the link.''' | ||
==Chemotherapy safety standards== | ==Chemotherapy safety standards== | ||
− | *'''2020:''' Dillmon et al. [https://doi.org/10.1200/JCO.19.02297 Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards] [https://pubmed.ncbi.nlm.nih.gov/31815576 PubMed] | + | *'''2020:''' Dillmon et al. [https://doi.org/10.1200/JCO.19.02297 Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards] [https://pubmed.ncbi.nlm.nih.gov/31815576/ PubMed] |
− | *'''2019:''' Celano et al. [https://doi.org/10.1200/JCO.18.01616 Safe handling of hazardous drugs: ASCO standards] [https://pubmed.ncbi.nlm.nih.gov/30620670 PubMed] | + | *'''2019:''' Celano et al. [https://doi.org/10.1200/JCO.18.01616 Safe handling of hazardous drugs: ASCO standards] [https://pubmed.ncbi.nlm.nih.gov/30620670/ PubMed] |
*'''2016:''' Neuss et al. [https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards, including standards for pediatric oncology] | *'''2016:''' Neuss et al. [https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards, including standards for pediatric oncology] | ||
− | *'''2010:''' Carrington et al. [https:// | + | *'''2010:''' Carrington et al. [https://doi.org/10.1111/j.1743-7563.2010.01321.x The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy] [https://pubmed.ncbi.nlm.nih.gov/20887505/ PubMed] |
==Dose adjustments== | ==Dose adjustments== | ||
*'''2021:''' Griggs et al. [https://doi.org/10.1200/jco.21.00471 Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update] | *'''2021:''' Griggs et al. [https://doi.org/10.1200/jco.21.00471 Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update] | ||
− | + | ||
− | *'''2012:''' Griggs et al. [https://doi.org/10.1200/jco.2011.39.9436 Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline]<ref>Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. [https://doi.org/10.1200/jco.2011.39.9436 link to original article] [https://pubmed.ncbi.nlm.nih.gov/22473167 PubMed]</ref> | + | *'''2012:''' Griggs et al. [https://doi.org/10.1200/jco.2011.39.9436 Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline]<ref>Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. [https://doi.org/10.1200/jco.2011.39.9436 link to original article] [https://pubmed.ncbi.nlm.nih.gov/22473167/ PubMed]</ref> |
==Antimicrobials== | ==Antimicrobials== | ||
Line 27: | Line 28: | ||
=Approved antineoplastics= | =Approved antineoplastics= | ||
− | ''This section contains drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound.'' | + | ''This section contains anticancer drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound. For drugs first approved within the current or prior calendar years, the date of initial approval is also provided here.'' |
==A== | ==A== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Abarelix (Plenaxis)]] | *[[Abarelix (Plenaxis)]] | ||
*[[Abemaciclib (Verzenio)]] | *[[Abemaciclib (Verzenio)]] | ||
Line 38: | Line 36: | ||
*[[Acalabrutinib (Calquence)]] | *[[Acalabrutinib (Calquence)]] | ||
*[[Aclarubicin (Aclacinomycin)]] | *[[Aclarubicin (Aclacinomycin)]] | ||
− | *[[ | + | *[[Adagrasib (Krazati)]] |
*[[Afatinib (Gilotrif)]] | *[[Afatinib (Gilotrif)]] | ||
*[[Aldesleukin (Proleukin)]] | *[[Aldesleukin (Proleukin)]] | ||
Line 50: | Line 48: | ||
*[[Amifostine (Ethyol)]] | *[[Amifostine (Ethyol)]] | ||
*[[Aminoglutethimide (Cytadren)]] | *[[Aminoglutethimide (Cytadren)]] | ||
− | *[[Amivantamab (Rybrevant)]] | + | *[[Amivantamab (Rybrevant)]] |
*[[Amrubicin (Calsed)]] | *[[Amrubicin (Calsed)]] | ||
*[[Amsacrine (Amsidine)]] | *[[Amsacrine (Amsidine)]] | ||
*[[Anastrozole (Arimidex)]] | *[[Anastrozole (Arimidex)]] | ||
*[[Ancestim (Stemgen)]] | *[[Ancestim (Stemgen)]] | ||
+ | *[[Anlotinib (Fukewei)]] | ||
*[[Apalutamide (Erleada)]] | *[[Apalutamide (Erleada)]] | ||
*[[Apatinib (Aitan)]] | *[[Apatinib (Aitan)]] | ||
*[[Arsenic trioxide (Trisenox)]] | *[[Arsenic trioxide (Trisenox)]] | ||
− | *[[Asciminib (Scemblix)]] | + | *[[Asciminib (Scemblix)]] |
*[[Asparaginase Erwinia chrysanthemi (Erwinaze)]] | *[[Asparaginase Erwinia chrysanthemi (Erwinaze)]] | ||
− | **[[Asparaginase erwinia chrysanthemi-rywn (Rylaze)]] | + | **[[Asparaginase erwinia chrysanthemi-rywn (Rylaze)]] |
*[[Atezolizumab (Tecentriq)]] | *[[Atezolizumab (Tecentriq)]] | ||
+ | *[[Aumolertinib (Amelie)]] | ||
*[[Avapritinib (Ayvakit)]] | *[[Avapritinib (Ayvakit)]] | ||
*[[Avelumab (Bavencio)]] | *[[Avelumab (Bavencio)]] | ||
Line 70: | Line 70: | ||
==B== | ==B== | ||
− | |||
− | |||
− | |||
− | |||
− | *[[ | + | |
+ | *[[BCG vaccine]] | ||
*[[Belantamab mafodotin (Blenrep)]] | *[[Belantamab mafodotin (Blenrep)]] | ||
*[[Belinostat (Beleodaq)]] | *[[Belinostat (Beleodaq)]] | ||
*[[Belotecan (Camptobell)]] | *[[Belotecan (Camptobell)]] | ||
− | *[[Belumosudil (Rezurock)]] | + | *[[Belumosudil (Rezurock)]] |
− | *[[Belzutifan (Welireg)]] | + | *[[Belzutifan (Welireg)]] |
*[[Bendamustine]] | *[[Bendamustine]] | ||
*[[Benralizumab (Fasenra)]] | *[[Benralizumab (Fasenra)]] | ||
*[[Bevacizumab (Avastin)]] | *[[Bevacizumab (Avastin)]] | ||
+ | **[[Bevacizumab-adcd (Vegzelga)]] | ||
+ | **[[Bevacizumab-aveg (Avegra)]] | ||
**[[Bevacizumab-awwb (Mvasi)]] | **[[Bevacizumab-awwb (Mvasi)]] | ||
+ | **[[Bevacizumab-aybi (Aybintio)]] | ||
**[[Bevacizumab-bvzr (Zirabev)]] | **[[Bevacizumab-bvzr (Zirabev)]] | ||
− | **[[Bevacizumab ( | + | **[[Bevacizumab-equi (Equidacent)]] |
− | **[[Bevacizumab ( | + | **[[Bevacizumab-maly (Alymsys)]] |
− | **[[Bevacizumab ( | + | **[[Bevacizumab-onbe (Onbevzi)]] |
− | **[[Bevacizumab ( | + | **[[Bevacizumab-tnjn (Avzivi)]] '''FDA approved 2023-12''' |
*[[Bexarotene (Targretin)]] | *[[Bexarotene (Targretin)]] | ||
*[[Bicalutamide (Casodex)]] | *[[Bicalutamide (Casodex)]] | ||
− | *[[Binimetinib | + | *[[Binimetinib (Mektovi)]] |
*[[Bleomycin (Blenoxane)]] | *[[Bleomycin (Blenoxane)]] | ||
*[[Blinatumomab (Blincyto)]] | *[[Blinatumomab (Blincyto)]] | ||
+ | *[[Borofalan-10B (Steboronine)]] | ||
*[[Bortezomib (Velcade)]] | *[[Bortezomib (Velcade)]] | ||
*[[Bosutinib (Bosulif)]] | *[[Bosutinib (Bosulif)]] | ||
Line 104: | Line 105: | ||
==C== | ==C== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Cabazitaxel (Jevtana)]] | *[[Cabazitaxel (Jevtana)]] | ||
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*[[Cabozantinib (Cometriq)]] | *[[Cabozantinib (Cometriq)]] | ||
*[[Calaspargase (Asparlas)]] | *[[Calaspargase (Asparlas)]] | ||
+ | *[[Camrelizumab (AiRuiKa)]] | ||
*[[Capecitabine (Xeloda)]] | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Capivasertib (Truqap)]] '''FDA approved 2023-11-16''' | ||
*[[Caplacizumab (Cablivi)]] | *[[Caplacizumab (Cablivi)]] | ||
*[[Capmatinib (Tabrecta)]] | *[[Capmatinib (Tabrecta)]] | ||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
*[[Carfilzomib (Kyprolis)]] | *[[Carfilzomib (Kyprolis)]] | ||
+ | *[[Carmofur (HCFU)]] | ||
*[[Carmustine (BCNU)]] | *[[Carmustine (BCNU)]] | ||
*[[Carmustine wafer, polifeprosan 20 (Gliadel)]] | *[[Carmustine wafer, polifeprosan 20 (Gliadel)]] | ||
− | |||
*[[Cemiplimab (Libtayo)]] | *[[Cemiplimab (Libtayo)]] | ||
*[[Ceritinib (Zykadia)]] | *[[Ceritinib (Zykadia)]] | ||
Line 127: | Line 127: | ||
*[[Chlorambucil (Leukeran)]] | *[[Chlorambucil (Leukeran)]] | ||
*[[Chlorozotocin (DCNU)]] | *[[Chlorozotocin (DCNU)]] | ||
− | *[[Ciltacabtagene autoleucel (Carvykti)]] | + | *[[Ciltacabtagene autoleucel (Carvykti)]] |
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
*[[Cladribine (Leustatin)]] | *[[Cladribine (Leustatin)]] | ||
Line 142: | Line 142: | ||
==D== | ==D== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Dabrafenib (Tafinlar)]] | *[[Dabrafenib (Tafinlar)]] | ||
Line 153: | Line 150: | ||
*[[Daratumumab (Darzalex)]] | *[[Daratumumab (Darzalex)]] | ||
*[[Daratumumab and hyaluronidase (Darzalex Faspro)]] | *[[Daratumumab and hyaluronidase (Darzalex Faspro)]] | ||
+ | *[[Daratumumab and vorhyaluronidase (Darzquro)]] | ||
+ | *[[Darinaparsin (Darvias)]] | ||
*[[Darolutamide (Nubeqa)]] | *[[Darolutamide (Nubeqa)]] | ||
*[[Dasatinib (Sprycel)]] | *[[Dasatinib (Sprycel)]] | ||
Line 161: | Line 160: | ||
*[[Dexamethasone (Decadron)]] | *[[Dexamethasone (Decadron)]] | ||
*[[Dinutuximab (Unituxin)]] | *[[Dinutuximab (Unituxin)]] | ||
+ | *[[Dinutuximab beta (Qarziba)]] | ||
*[[Docetaxel (Taxotere)]] | *[[Docetaxel (Taxotere)]] | ||
− | *[[Dostarlimab (Jemperli)]] | + | *[[Donafenib (Zepsun)]] |
+ | *[[Dostarlimab (Jemperli)]] | ||
*[[Doxifluridine (Didox)]] | *[[Doxifluridine (Didox)]] | ||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | |||
*[[Durvalumab (Imfinzi)]] | *[[Durvalumab (Imfinzi)]] | ||
*[[Dutasteride (Avodart)]] | *[[Dutasteride (Avodart)]] | ||
Line 171: | Line 171: | ||
==E== | ==E== | ||
− | + | *[[Eflornithine (Iwilfin)]] '''FDA approved 2023-12-13''' | |
− | + | *[[Elacestrant (Orserdu)]] '''FDA approved 2023-01-27''' | |
− | |||
− | |||
− | |||
*[[Elotuzumab (Empliciti)]] | *[[Elotuzumab (Empliciti)]] | ||
+ | *[[Elranatamab (Elrexfio)]] '''FDA approved on 2023-08-14''' | ||
*[[Emapalumab (Gamifant)]] | *[[Emapalumab (Gamifant)]] | ||
*[[Enasidenib (Idhifa)]] | *[[Enasidenib (Idhifa)]] | ||
*[[Encorafenib (Braftovi)]] | *[[Encorafenib (Braftovi)]] | ||
*[[Enfortumab vedotin (Padcev)]] | *[[Enfortumab vedotin (Padcev)]] | ||
+ | *[[Ensartinib (Ensacove)]] | ||
*[[Entrectinib (Rozlytrek)]] | *[[Entrectinib (Rozlytrek)]] | ||
+ | *[[Envafolimab (Enweida)]] | ||
*[[Enzalutamide (Xtandi)]] | *[[Enzalutamide (Xtandi)]] | ||
+ | *[[Epcoritamab (Epkinly)]] '''FDA approved 2023-05-19''' | ||
*[[Epirubicin (Ellence)]] | *[[Epirubicin (Ellence)]] | ||
*[[Erdafitinib (Balversa)]] | *[[Erdafitinib (Balversa)]] | ||
Line 194: | Line 195: | ||
==F== | ==F== | ||
− | + | *[[Fadrozole (Afema)]] | |
− | |||
− | |||
− | |||
− | *[[ | ||
*[[Fedratinib (Inrebic)]] | *[[Fedratinib (Inrebic)]] | ||
*[[Fluorouracil (5-FU)]] | *[[Fluorouracil (5-FU)]] | ||
*[[Fludarabine (Fludara)]] | *[[Fludarabine (Fludara)]] | ||
+ | *[[Flumatinib (Xinfu)]] | ||
*[[Flutamide (Eulexin)]] | *[[Flutamide (Eulexin)]] | ||
− | *[[Folinic acid | + | *[[Leucovorin (Folinic acid)]] |
*[[Forodesine (Fodosine)]] | *[[Forodesine (Fodosine)]] | ||
*[[Fostamatinib (Tavalisse)]] | *[[Fostamatinib (Tavalisse)]] | ||
*[[Fotemustine (Muphoran)]] | *[[Fotemustine (Muphoran)]] | ||
+ | *[[Fruquintinib (Elunate)]] | ||
*[[Fulvestrant (Faslodex)]] | *[[Fulvestrant (Faslodex)]] | ||
+ | *[[Furmonertinib (Ivesa)]] | ||
+ | *[[Futibatinib (Lytgobi)]] | ||
==G== | ==G== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Gallium Ga 68 gozetotide (Locametz)]] | *[[Gallium Ga 68 gozetotide (Locametz)]] | ||
Line 221: | Line 219: | ||
*[[Gilteritinib (Xospata)]] | *[[Gilteritinib (Xospata)]] | ||
*[[Glasdegib (Daurismo)]] | *[[Glasdegib (Daurismo)]] | ||
+ | *[[Glofitamab (Columvi)]] '''FDA approved 2023-06-15''' | ||
*[[Goserelin (Zoladex)]] | *[[Goserelin (Zoladex)]] | ||
==H== | ==H== | ||
− | + | *[[Heptaplatin (SunPla)]] | |
− | + | *[[Histamine dihydrochloride (Ceplene)]] | |
− | |||
− | |||
− | |||
− | *[[ | ||
*[[Histrelin (Vantas)]] | *[[Histrelin (Vantas)]] | ||
*[[Hydrocortisone (Cortef)]] | *[[Hydrocortisone (Cortef)]] | ||
Line 235: | Line 230: | ||
==I== | ==I== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Ibritumomab tiuxetan (Zevalin)]] | *[[Ibritumomab tiuxetan (Zevalin)]] | ||
Line 244: | Line 236: | ||
*[[Icotinib (Conmana)]] | *[[Icotinib (Conmana)]] | ||
*[[Idarubicin (Idamycin)]] | *[[Idarubicin (Idamycin)]] | ||
− | *[[Idecabtagene vicleucel (Abecma)]] | + | *[[Idecabtagene vicleucel (Abecma)]] |
*[[Idelalisib (Zydelig)]] | *[[Idelalisib (Zydelig)]] | ||
*[[Ifosfamide (Ifex)]] | *[[Ifosfamide (Ifex)]] | ||
*[[Imatinib (Gleevec)]] | *[[Imatinib (Gleevec)]] | ||
− | *[[ | + | *[[Imetelstat (Rytelo)]] '''FDA approved 2024-06-06''' |
+ | *[[Infigratinib (Truseltiq)]] | ||
*[[Inotuzumab ozogamicin (Besponsa)]] | *[[Inotuzumab ozogamicin (Besponsa)]] | ||
*[[Interferon alfa-2a (Roferon-A)]] | *[[Interferon alfa-2a (Roferon-A)]] | ||
*[[Interferon alfa-2b (Intron-A)]] | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | *[[Interferon gamma-1a (Imunomax-γ)]] | ||
*[[Interferon gamma-1b (Actimmune)]] | *[[Interferon gamma-1b (Actimmune)]] | ||
*[[Iobenguane I 131 (Azedra)]] | *[[Iobenguane I 131 (Azedra)]] | ||
*[[Iodine-131]] | *[[Iodine-131]] | ||
*[[Ipilimumab (Yervoy)]] | *[[Ipilimumab (Yervoy)]] | ||
− | |||
*[[Irinotecan (Camptosar)]] | *[[Irinotecan (Camptosar)]] | ||
*[[Irinotecan liposome (Onivyde)]] | *[[Irinotecan liposome (Onivyde)]] | ||
Line 270: | Line 263: | ||
==L== | ==L== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Lanreotide (Somatuline)]] | *[[Lanreotide (Somatuline)]] | ||
*[[Lanreotide LAR (Somatuline Depot)]] | *[[Lanreotide LAR (Somatuline Depot)]] | ||
*[[Lapatinib (Tykerb)]] | *[[Lapatinib (Tykerb)]] | ||
*[[Larotrectinib (Vitrakvi)]] | *[[Larotrectinib (Vitrakvi)]] | ||
− | *[[Lasofoxifene (Fablyn)]] | + | *[[Lasofoxifene (Fablyn)]] |
*[[Lenalidomide (Revlimid)]] | *[[Lenalidomide (Revlimid)]] | ||
*[[Lenvatinib (Lenvima)]] | *[[Lenvatinib (Lenvima)]] | ||
− | |||
*[[Letrozole (Femara)]] | *[[Letrozole (Femara)]] | ||
*[[Leuprolide (Lupron)]] | *[[Leuprolide (Lupron)]] | ||
*[[Levoleucovorin (Fusilev)]] | *[[Levoleucovorin (Fusilev)]] | ||
− | *[[ | + | *[[Lifileuecel (Contego)]] '''FDA approved 2024-02-16''' |
+ | *[[Lisocabtagene maraleucel (Breyanzi)]] | ||
*[[Lobaplatin (D-19466)]] | *[[Lobaplatin (D-19466)]] | ||
*[[Lomustine (CCNU)]] | *[[Lomustine (CCNU)]] | ||
− | *[[Loncastuximab tesirine (Zynlonta)]] | + | *[[Loncastuximab tesirine (Zynlonta)]] |
*[[Lorlatinib (Lorbrena)]] | *[[Lorlatinib (Lorbrena)]] | ||
*[[Lurbinectedin (Zepzelca)]] | *[[Lurbinectedin (Zepzelca)]] | ||
*[[Lutetium Lu 177 dotatate (Lutathera)]] | *[[Lutetium Lu 177 dotatate (Lutathera)]] | ||
− | *[[Lutetium Lu 177 vipivotide tetraxetan (Pluvicto)]] | + | *[[Lutetium Lu 177 vipivotide tetraxetan (Pluvicto)]] |
==M== | ==M== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Margetuximab (Margenza)]] | *[[Margetuximab (Margenza)]] | ||
*[[Mechlorethamine (Mustargen)]] | *[[Mechlorethamine (Mustargen)]] | ||
− | *[[Medroxyprogesterone (MPA)]] | + | *[[Medroxyprogesterone acetate (MPA)]] |
*[[Megestrol (Megace)]] | *[[Megestrol (Megace)]] | ||
*[[Melphalan (Alkeran)]] | *[[Melphalan (Alkeran)]] | ||
+ | *[[Melphalan for Injection-Hepatic Delivery System (Hepzato Kit)]] '''FDA approved on 2023-08-14''' | ||
*[[Mepolizumab (Nucala)]] | *[[Mepolizumab (Nucala)]] | ||
*[[Mercaptopurine (6-MP)]] | *[[Mercaptopurine (6-MP)]] | ||
Line 311: | Line 299: | ||
*[[Midostaurin (Rydapt)]] | *[[Midostaurin (Rydapt)]] | ||
*[[Mifamurtide (Mepact)]] | *[[Mifamurtide (Mepact)]] | ||
− | *[[Mitomycin (Jelmyto)]] | + | *[[Miriplatin (Miripla)]] |
+ | *[[Mirvetuximab soravtansine (Elahere)]] | ||
+ | *[[Mitomycin pyelocalyceal (Jelmyto)]] | ||
*[[Mitomycin (Mutamycin)]] | *[[Mitomycin (Mutamycin)]] | ||
*[[Mitotane (Lysodren)]] | *[[Mitotane (Lysodren)]] | ||
*[[Mitoxantrone (Novantrone)]] | *[[Mitoxantrone (Novantrone)]] | ||
− | *[[Mobocertinib (Exkivity)]] | + | *[[Mobocertinib (Exkivity)]] |
*[[Mogamulizumab (Poteligeo)]] | *[[Mogamulizumab (Poteligeo)]] | ||
+ | *[[Momelotinib (Ojjaara)]] '''FDA approved 2023-09-15''' | ||
+ | *[[Mosunetuzumab (Lunsumio)]] | ||
*[[Moxetumomab pasudotox (Lumoxiti)]] | *[[Moxetumomab pasudotox (Lumoxiti)]] | ||
==N== | ==N== | ||
− | + | *[[Nadofaragene firadenovec (Adstiladrin)]] | |
− | |||
− | |||
− | |||
− | |||
*[[Naxitamab (Danyelza)]] | *[[Naxitamab (Danyelza)]] | ||
*[[Necitumumab (Portrazza)]] | *[[Necitumumab (Portrazza)]] | ||
*[[Nedaplatin (Aqupla)]] | *[[Nedaplatin (Aqupla)]] | ||
*[[Nelarabine (Arranon)]] | *[[Nelarabine (Arranon)]] | ||
− | |||
*[[Neratinib (Nerlynx)]] | *[[Neratinib (Nerlynx)]] | ||
*[[Nilotinib (Tasigna)]] | *[[Nilotinib (Tasigna)]] | ||
Line 337: | Line 324: | ||
*[[Nintedanib (Vargatef)]] | *[[Nintedanib (Vargatef)]] | ||
*[[Niraparib (Zejula)]] | *[[Niraparib (Zejula)]] | ||
+ | *[[Niraparib and abiraterone (Akeega)]] '''FDA approved 2023-08-11''' | ||
+ | *[[Nirogacestat (Ogsiveo)]] '''FDA approved 2023-11-27''' | ||
*[[Nivolumab (Opdivo)]] | *[[Nivolumab (Opdivo)]] | ||
− | *[[Nivolumab and relatlimab (Opdualag)]] '''FDA approved | + | *[[Nivolumab and relatlimab (Opdualag)]] |
− | + | *[[Nogapendekin alfa inbakicept (Anktiva)]] '''FDA approved 2024-04-22''' | |
*[[Non-pegylated liposomal doxorubicin (Myocet)]] | *[[Non-pegylated liposomal doxorubicin (Myocet)]] | ||
*[[Norethandrolone (Nilevar)]] | *[[Norethandrolone (Nilevar)]] | ||
Line 345: | Line 334: | ||
==O== | ==O== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Obinutuzumab (Gazyva)]] | *[[Obinutuzumab (Gazyva)]] | ||
*[[Octreotide (Sandostatin)]] | *[[Octreotide (Sandostatin)]] | ||
Line 354: | Line 340: | ||
*[[Ofatumumab (Arzerra)]] | *[[Ofatumumab (Arzerra)]] | ||
*[[Olaparib (Lynparza)]] | *[[Olaparib (Lynparza)]] | ||
+ | *[[Olutasidenib (Rezlidhia)]] | ||
+ | *[[Olverembatinib (HQP-1351)]] | ||
*[[Omacetaxine (Synribo)]] | *[[Omacetaxine (Synribo)]] | ||
*[[Osimertinib (Tagrisso)]] | *[[Osimertinib (Tagrisso)]] | ||
Line 359: | Line 347: | ||
==P== | ==P== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Paclitaxel (Taxol)]] | *[[Paclitaxel (Taxol)]] | ||
*[[Paclitaxel, nanoparticle albumin-bound (Abraxane)]] | *[[Paclitaxel, nanoparticle albumin-bound (Abraxane)]] | ||
*[[Paclitaxel, polymeric micelle-bound (Genexol-PM)]] | *[[Paclitaxel, polymeric micelle-bound (Genexol-PM)]] | ||
− | *[[Pacritinib (Vonjo)]] | + | *[[Pacritinib (Vonjo)]] |
+ | *[[Padeliporfin (Tookad)]] | ||
*[[Palbociclib (Ibrance)]] | *[[Palbociclib (Ibrance)]] | ||
*[[Panitumumab (Vectibix)]] | *[[Panitumumab (Vectibix)]] | ||
Line 375: | Line 361: | ||
*[[Peginterferon alfa-2a (Pegasys)]] | *[[Peginterferon alfa-2a (Pegasys)]] | ||
*[[Peginterferon alfa-2b (Sylatron)]] | *[[Peginterferon alfa-2b (Sylatron)]] | ||
+ | *[[Pegylated liposomal doxorubicin (Doxil)]] | ||
*[[Pembrolizumab (Keytruda)]] | *[[Pembrolizumab (Keytruda)]] | ||
*[[Pemetrexed (Alimta)]] | *[[Pemetrexed (Alimta)]] | ||
*[[Pemigatinib (Pemazyre)]] | *[[Pemigatinib (Pemazyre)]] | ||
+ | *[[Penpulimab (Anniko)]] | ||
*[[Pentostatin (Nipent)]] | *[[Pentostatin (Nipent)]] | ||
*[[Pertuzumab (Perjeta)]] | *[[Pertuzumab (Perjeta)]] | ||
− | *[[Pertuzumab | + | *[[Pertuzumab and Trastuzumab hyaluronidase (Phesgo)]] |
*[[Pexidartinib (Turalio)]] | *[[Pexidartinib (Turalio)]] | ||
+ | *[[Pipobroman (Vercyte)]] | ||
*[[Pirarubicin (THP)]] | *[[Pirarubicin (THP)]] | ||
+ | *[[Pirtobrutinib (Jaypirca)]] '''FDA approved 2023-01-27''' | ||
*[[Pixantrone (Pixuvri)]] | *[[Pixantrone (Pixuvri)]] | ||
*[[Polatuzumab vedotin (Polivy)]] | *[[Polatuzumab vedotin (Polivy)]] | ||
Line 393: | Line 383: | ||
*[[Prednisolone (Millipred)]] | *[[Prednisolone (Millipred)]] | ||
*[[Procarbazine (Matulane)]] | *[[Procarbazine (Matulane)]] | ||
+ | *[[Pyrotinib (Irene)]] | ||
+ | |||
+ | ==Q== | ||
+ | *[[Quizartinib (Vanflyta)]] | ||
==R== | ==R== | ||
− | + | *[[Racotumomab (Vaxira)]] | |
− | + | *[[Radium-223 (Xofigo)]] | |
− | |||
− | |||
− | |||
− | *[[Radium | ||
*[[Radotinib (Supect)]] | *[[Radotinib (Supect)]] | ||
*[[Raltitrexed (Tomudex)]] | *[[Raltitrexed (Tomudex)]] | ||
Line 409: | Line 399: | ||
*[[Regorafenib (Stivarga)]] | *[[Regorafenib (Stivarga)]] | ||
*[[Relugolix (Orgovyx)]] | *[[Relugolix (Orgovyx)]] | ||
+ | *[[Repotrectinib (Augtyro)]] '''FDA approved 2023-11-15''' | ||
+ | *[[Retifanlimab (Zynyz)]] '''FDA approved 2023-03-22''' | ||
*[[Ribociclib (Kisqali)]] | *[[Ribociclib (Kisqali)]] | ||
*[[Ripretinib (Qinlock)]] | *[[Ripretinib (Qinlock)]] | ||
Line 415: | Line 407: | ||
**[[Rituximab-arrx (Riabni)]] | **[[Rituximab-arrx (Riabni)]] | ||
**[[Rituximab-pvvr (Ruxience)]] | **[[Rituximab-pvvr (Ruxience)]] | ||
− | **[[Rituximab (Blitzima)]] | + | **[[Rituximab-blit (Blitzima)]] |
− | **[[Rituximab (Ritemvia)]] | + | **[[Rituximab-rite (Ritemvia)]] |
− | **[[Rituximab (Rixathon)]] | + | **[[Rituximab-rixa (Rixathon)]] |
− | **[[Rituximab (Riximyo)]] | + | **[[Rituximab-rixi (Riximyo)]] |
− | *[[Rituximab and hyaluronidase human ( | + | *[[Rituximab and hyaluronidase human (Rituxan Hycela)]] |
*[[Romidepsin (Istodax)]] | *[[Romidepsin (Istodax)]] | ||
+ | *[[Ropeginterferon alfa-2b (Besremi)]] | ||
*[[Rucaparib (Rubraca)]] | *[[Rucaparib (Rubraca)]] | ||
*[[Ruxolitinib (Jakafi)]] | *[[Ruxolitinib (Jakafi)]] | ||
==S== | ==S== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Sacituzumab govitecan (Trodelvy)]] | *[[Sacituzumab govitecan (Trodelvy)]] | ||
Line 435: | Line 425: | ||
*[[Selpercatinib (Retevmo)]] | *[[Selpercatinib (Retevmo)]] | ||
*[[Selumetinib (Koselugo)]] | *[[Selumetinib (Koselugo)]] | ||
+ | *[[Serplulimab (Hansizhuang)]] | ||
*[[Sintilimab (Tyvyt)]] | *[[Sintilimab (Tyvyt)]] | ||
*[[Sipuleucel-T (Provenge)]] | *[[Sipuleucel-T (Provenge)]] | ||
− | *[[Sirolimus protein-bound particles (Fyarro)]] | + | *[[Sirolimus protein-bound particles (Fyarro)]] |
*[[Sonidegib (Odomzo)]] | *[[Sonidegib (Odomzo)]] | ||
*[[Sorafenib (Nexavar)]] | *[[Sorafenib (Nexavar)]] | ||
− | *[[Sotorasib (Lumakras)]] | + | *[[Sotorasib (Lumakras)]] |
*[[Stilbamidine]] | *[[Stilbamidine]] | ||
*[[Streptozocin (Zanosar)]] | *[[Streptozocin (Zanosar)]] | ||
*[[Strontium-89 (Metastron)]] | *[[Strontium-89 (Metastron)]] | ||
+ | *[[Sugemalimab (Cejemly)]] | ||
*[[Sunitinib (Sutent)]] | *[[Sunitinib (Sutent)]] | ||
*[[Suramin (Antrypol)]] | *[[Suramin (Antrypol)]] | ||
==T== | ==T== | ||
− | + | *[[Tabelecleucel (Ebvallo)]] | |
− | |||
− | |||
− | |||
*[[Tafasitamab (Monjuvi)]] | *[[Tafasitamab (Monjuvi)]] | ||
*[[Tagraxofusp (Elzonris)]] | *[[Tagraxofusp (Elzonris)]] | ||
*[[Talazoparib (Talzenna)]] | *[[Talazoparib (Talzenna)]] | ||
*[[Talimogene laherparepvec (Imlygic)]] | *[[Talimogene laherparepvec (Imlygic)]] | ||
+ | *[[Taloporfin (Laserphyrin)]] | ||
+ | *[[Talquetamab (Talvey)]] '''FDA approved 2023-08-09''' | ||
+ | *[[Tamibarotene (Amnoid)]] | ||
*[[Tamoxifen (Nolvadex)]] | *[[Tamoxifen (Nolvadex)]] | ||
+ | *[[Tarlatamab (Imdelltra)]] '''FDA approved 2024-05-16''' | ||
*[[Tasonermin (Beromun)]] | *[[Tasonermin (Beromun)]] | ||
*[[Tazemetostat (Tazverik)]] | *[[Tazemetostat (Tazverik)]] | ||
+ | *[[Tebentafusp (Kimmtrak)]] | ||
+ | *[[Teclistamab (Tecvayli)]] | ||
*[[Tegafur and uracil (UFT)]] | *[[Tegafur and uracil (UFT)]] | ||
*[[Tegafur, gimeracil, oteracil (Teysuno, S-1)]] | *[[Tegafur, gimeracil, oteracil (Teysuno, S-1)]] | ||
− | *[[ | + | *[[Temoporfin (Foscan)]] |
*[[Temozolomide (Temodar)]] | *[[Temozolomide (Temodar)]] | ||
*[[Temsirolimus (Torisel)]] | *[[Temsirolimus (Torisel)]] | ||
*[[Teniposide (Vumon)]] | *[[Teniposide (Vumon)]] | ||
− | *[[Tepotinib (Tepmetko)]] | + | *[[Tepotinib (Tepmetko)]] |
*[[Thalidomide (Thalomid)]] | *[[Thalidomide (Thalomid)]] | ||
*[[Thioguanine (Tabloid)]] | *[[Thioguanine (Tabloid)]] | ||
*[[Thiotepa (Tepadina)]] | *[[Thiotepa (Tepadina)]] | ||
*[[Thiotepa (Thioplex)]] | *[[Thiotepa (Thioplex)]] | ||
+ | *[[Tirabrutinib (Velexbru)]] | ||
*[[Tisagenlecleucel (Kymriah)]] | *[[Tisagenlecleucel (Kymriah)]] | ||
− | *[[Tisotumab vedotin (Tivdak)]] | + | *[[Tisotumab vedotin (Tivdak)]] |
*[[Topotecan (Hycamtin)]] | *[[Topotecan (Hycamtin)]] | ||
*[[Toremifene (Fareston)]] | *[[Toremifene (Fareston)]] | ||
− | *[[Toripalimab ( | + | *[[Toripalimab (Loqtorzi)]] '''FDA approved 2023-10-27''' |
*[[Tositumomab and I-131 (Bexxar)]] | *[[Tositumomab and I-131 (Bexxar)]] | ||
+ | *[[Tovorafenib (Ojemda)]] '''FDA approved 2024-04-23''' | ||
*[[Trabectedin (Yondelis)]] | *[[Trabectedin (Yondelis)]] | ||
*[[Trametinib (Mekinist)]] | *[[Trametinib (Mekinist)]] | ||
Line 482: | Line 479: | ||
**[[Trastuzumab-dkst (Ogivri)]] | **[[Trastuzumab-dkst (Ogivri)]] | ||
**[[Trastuzumab-dttb (Ontruzant)]] | **[[Trastuzumab-dttb (Ontruzant)]] | ||
+ | **[[Trastuzumab-herw (Herwenda)]] | ||
**[[Trastuzumab-pkrb (Herzuma)]] | **[[Trastuzumab-pkrb (Herzuma)]] | ||
**[[Trastuzumab-qyyp (Trazimera)]] | **[[Trastuzumab-qyyp (Trazimera)]] | ||
− | **[[Trastuzumab (Zercepac)]] | + | **[[Trastuzumab-strf (Hercessi)]] '''FDA approved 2024-04-29''' |
+ | **[[Trastuzumab-zerc (Zercepac)]] | ||
*[[Trastuzumab and hyaluronidase (Herceptin Hylecta)]] | *[[Trastuzumab and hyaluronidase (Herceptin Hylecta)]] | ||
+ | *[[Trastuzumab deruxtecan (Enhertu)]] | ||
+ | *[[Trastuzumab emtansine (Kadcyla)]] | ||
+ | *[[Tremelimumab (Imjudo)]] | ||
*[[Treosulfan (Ovastat)]] | *[[Treosulfan (Ovastat)]] | ||
*[[Trifluridine and tipiracil (Lonsurf)]] | *[[Trifluridine and tipiracil (Lonsurf)]] | ||
Line 491: | Line 493: | ||
*[[Trimetrexate (Neutrexin)]] | *[[Trimetrexate (Neutrexin)]] | ||
*[[Triptorelin (Trelstar LA)]] | *[[Triptorelin (Trelstar LA)]] | ||
+ | *[[Trofosfamide (Ixoten)]] | ||
*[[Tucatinib (Tukysa)]] | *[[Tucatinib (Tukysa)]] | ||
==U== | ==U== | ||
− | + | *[[Ublituximab (Briumvi)]] '''FDA approved 2023-01-06''' | |
− | |||
− | |||
− | |||
− | *[[ | ||
− | |||
==V== | ==V== | ||
− | + | *[[Valemetostat (Ezharmia)]] | |
− | |||
− | |||
− | |||
*[[Valrubicin (Valstar)]] | *[[Valrubicin (Valstar)]] | ||
*[[Vandetanib (Caprelsa)]] | *[[Vandetanib (Caprelsa)]] | ||
Line 511: | Line 506: | ||
*[[Vinblastine (Velban)]] | *[[Vinblastine (Velban)]] | ||
*[[Vincristine (Oncovin)]] | *[[Vincristine (Oncovin)]] | ||
− | |||
*[[Vindesine (Eldisine)]] | *[[Vindesine (Eldisine)]] | ||
*[[Vinflunine (Javlor)]] | *[[Vinflunine (Javlor)]] | ||
Line 520: | Line 514: | ||
==Z== | ==Z== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Zanubrutinib (Brukinsa)]] | *[[Zanubrutinib (Brukinsa)]] | ||
+ | *[[Zimberelimab (Yu Duo)]] | ||
*[[Ziv-aflibercept (Zaltrap)]] | *[[Ziv-aflibercept (Zaltrap)]] | ||
+ | **[[Aflibercept-jbvf (Yesafili)]] '''FDA approved 2024-05''' | ||
+ | **[[Aflibercept-yszy (Opuviz)]] '''FDA approved 2024-05''' | ||
=Discontinued antineoplastics= | =Discontinued antineoplastics= | ||
Line 531: | Line 525: | ||
==A== | ==A== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Aminopterin]] | *[[Aminopterin]] | ||
*[[Asparaginase (Elspar)]] | *[[Asparaginase (Elspar)]] | ||
==D== | ==D== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Daunorubicin liposomal (DaunoXome)]] | *[[Daunorubicin liposomal (DaunoXome)]] | ||
*[[Denileukin diftitox (Ontak)]] | *[[Denileukin diftitox (Ontak)]] | ||
Line 548: | Line 536: | ||
==E== | ==E== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Edrecolomab (Panorex)]] | *[[Edrecolomab (Panorex)]] | ||
+ | *[[Ethinylestradiol]] | ||
==F== | ==F== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Floxuridine (FUDR)]] | *[[Floxuridine (FUDR)]] | ||
*[[Fluoxymesterone (Halotestin)]] | *[[Fluoxymesterone (Halotestin)]] | ||
Line 564: | Line 547: | ||
==L== | ==L== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Levamisole (Ergamisol)]] | *[[Levamisole (Ergamisol)]] | ||
==M== | ==M== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Melphalan flufenamide (Pepaxto)]] | *[[Melphalan flufenamide (Pepaxto)]] | ||
==O== | ==O== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Olaratumab (Lartruvo)]] | *[[Olaratumab (Lartruvo)]] | ||
==P== | ==P== | ||
− | + | *[[Paclitaxel poliglumex (Opaxio)]] | |
− | |||
− | |||
− | |||
*[[Plicamycin (Mithracin)]] | *[[Plicamycin (Mithracin)]] | ||
+ | *[[Polyestradiol phosphate (Estradurin)]] | ||
==S== | ==S== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Semustine (MeCCNU)]] | *[[Semustine (MeCCNU)]] | ||
==T== | ==T== | ||
− | |||
− | |||
− | |||
− | |||
*[[Testolactone (Teslac)]] | *[[Testolactone (Teslac)]] | ||
+ | *[[Triethylenemelamine (Tretamine)]] | ||
==U== | ==U== | ||
− | + | *[[Umbralisib (Ukoniq)]] | |
− | |||
− | |||
− | |||
*[[Uracil mustard]] | *[[Uracil mustard]] | ||
*[[Urethane]] | *[[Urethane]] | ||
+ | |||
+ | ==V== | ||
+ | *[[Vincristine liposomal (Marqibo)]] | ||
=Investigational antineoplastics= | =Investigational antineoplastics= | ||
''This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.'' | ''This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.'' | ||
==A== | ==A== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Abexinostat (PCI-24781)]] | *[[Abexinostat (PCI-24781)]] | ||
*[[Actinium Ac 225 lintuzumab (Actimab-A)]] | *[[Actinium Ac 225 lintuzumab (Actimab-A)]] | ||
− | |||
*[[Adavosertib (MK-1775)]] | *[[Adavosertib (MK-1775)]] | ||
− | *[[Adenovirus-interferon-γ ( | + | *[[Adebrelimab (SHR-1316)]] |
− | *[[Afuresertib ( | + | *[[Adenovirus-interferon-γ (TG-1042)]] |
− | *[[Alisertib ( | + | *[[Afamitresgene Autoleucel (ADP-A2M4)]] |
+ | *[[Afuresertib (GSK-2110183)]] | ||
+ | *[[Agatolimod (PF-3512676)]] | ||
+ | *[[Alisertib (MLN-8237)]] | ||
*[[Amatuximab (MORAb-009)]] | *[[Amatuximab (MORAb-009)]] | ||
− | |||
*[[Amonafide (Quinamed)]] | *[[Amonafide (Quinamed)]] | ||
− | *[[Apocept ( | + | *[[Apocept (APG-101)]] |
− | *[[Astuprotimut-R ( | + | *[[Astuprotimut-R (GSK-1572932A)]] |
==B== | ==B== | ||
− | + | ||
− | + | *[[Barasertib (AZD-1152)]] | |
− | + | *[[Bavituximab (PGN-401)]] | |
− | + | *[[Befotertinib (D-0316)]] | |
− | *[[ | ||
− | *[[ | ||
*[[Belagenpumatucel-L (Lucanix)]] | *[[Belagenpumatucel-L (Lucanix)]] | ||
− | *[[ | + | *[[BE-CAR7]] |
+ | *[[BHQ-880]] | ||
+ | *[[Birtamimab (NEOD-001)]] | ||
*[[BL22 immunotoxin (CAT-3888)]] | *[[BL22 immunotoxin (CAT-3888)]] | ||
− | *[[Buparlisib ( | + | *[[Buparlisib (BKM-120)]] |
==C== | ==C== | ||
− | + | *[[CARv3-TEAM-E T-cells]] | |
− | |||
− | |||
− | |||
− | *[[ | ||
*[[Catumaxomab (Removab)]] '''in US clinical trials''' | *[[Catumaxomab (Removab)]] '''in US clinical trials''' | ||
*[[Cediranib (Recentin)]] | *[[Cediranib (Recentin)]] | ||
*[[Cixutumumab (IMC-A12)]] | *[[Cixutumumab (IMC-A12)]] | ||
− | *[[Coltuximab ravtansine ( | + | *[[Coltuximab ravtansine (SAR-3419)]] |
*[[Crenolanib (CP-868,596)]] | *[[Crenolanib (CP-868,596)]] | ||
*[[Custirsen (OGX-011)]] | *[[Custirsen (OGX-011)]] | ||
==D== | ==D== | ||
− | + | ||
− | + | *[[Dalpiciclib (SHR-6390)]] | |
− | + | *[[Danicopan (ALXN-2040)]] | |
− | + | *[[Datopotamab deruxtecan (DS-1062)]] | |
− | *[[ | ||
*[[Denintuzumab mafodotin (SGN-CD19A)]] | *[[Denintuzumab mafodotin (SGN-CD19A)]] | ||
− | *[[Dinaciclib (SCH 727965)]] | + | *[[Dinaciclib (SCH-727965)]] |
− | *[[Discodermolide ( | + | *[[Divarasib (GDC-6036)]] |
− | *[[ | + | *[[Discodermolide (XAA-296)]] |
+ | *[[DMUC-5754A]] | ||
*[[Dovitinib (TKI-258)]] | *[[Dovitinib (TKI-258)]] | ||
==E== | ==E== | ||
− | |||
− | |||
− | |||
− | |||
*[[Emepepimut-S (Stimuvax)]] | *[[Emepepimut-S (Stimuvax)]] | ||
− | *[[ | + | *[[Eluvixtamab (AMG-330)]] |
*[[Entinostat (SNDX-275)]] | *[[Entinostat (SNDX-275)]] | ||
*[[Entospletinib (GS-9973)]] | *[[Entospletinib (GS-9973)]] | ||
− | *[[ | + | *[[Envonalkib (TQ-B3139)]] |
*[[Epratuzumab (LymphoCide)]] | *[[Epratuzumab (LymphoCide)]] | ||
*[[Etirinotecan pegol (NKTR-102)]] | *[[Etirinotecan pegol (NKTR-102)]] | ||
==F== | ==F== | ||
− | + | *[[Farletuzumab (MORAb-003)]] | |
− | + | *[[Figitumumab (CP-751,871)]] | |
− | |||
− | |||
*[[Filanesib (ARRY-520)]] | *[[Filanesib (ARRY-520)]] | ||
− | |||
− | |||
− | |||
==G== | ==G== | ||
− | |||
− | |||
− | |||
− | |||
*[[G207]] | *[[G207]] | ||
*[[Galeterone (TOK-001)]] | *[[Galeterone (TOK-001)]] | ||
− | *[[Galunisertib ( | + | *[[Galunisertib (LY-2157299)]] |
*[[Ganetespib (STA-9090)]] | *[[Ganetespib (STA-9090)]] | ||
− | *[[Ganitumab (AMG 479)]] | + | *[[Ganitumab (AMG-479)]] |
− | *[[Gemcitabine elaidate (CP-4126 | + | *[[GD2-CART01]] |
− | *[[Glembatumumab vedotin (CDX-011) | + | *[[Gemcitabine elaidate (CP-4126)]] |
+ | *[[Glembatumumab vedotin (CDX-011)]] | ||
*[[Guadecitabine (SGI-110)]] | *[[Guadecitabine (SGI-110)]] | ||
==H== | ==H== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[HER2 peptide vaccine (AE37)]] | *[[HER2 peptide vaccine (AE37)]] | ||
*[[Hu5F9-G4]] | *[[Hu5F9-G4]] | ||
==I== | ==I== | ||
− | + | ||
− | + | *[[Idasanutlin (RG-7388)]] | |
− | + | *[[IMA-901]] | |
− | + | *[[Indatuximab ravtansine (BT-062)]] | |
− | *[[Idasanutlin ( | ||
− | *[[ | ||
− | |||
− | *[[Indatuximab ravtansine ( | ||
*[[Ipatasertib (GDC-0068)]] | *[[Ipatasertib (GDC-0068)]] | ||
− | *[[IPH 2101]] | + | *[[IPH-2101]] |
==J== | ==J== | ||
Line 732: | Line 673: | ||
==L== | ==L== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Lapuleucel-T (DN24-02)]] | *[[Lapuleucel-T (DN24-02)]] | ||
*[[Lestaurtinib (CEP-701)]] | *[[Lestaurtinib (CEP-701)]] | ||
Line 742: | Line 680: | ||
*[[Lorvotuzumab mertansine (BB-10901)]] | *[[Lorvotuzumab mertansine (BB-10901)]] | ||
*[[Lutetium-177-PSMA-617]] | *[[Lutetium-177-PSMA-617]] | ||
− | *[[ | + | *[[LY-3023414]] |
==M== | ==M== | ||
− | + | *[[Magrolimab (Hu5F9-G4)]] | |
− | |||
− | |||
− | |||
*[[Mapatumumab (HGS-ETR1)]] | *[[Mapatumumab (HGS-ETR1)]] | ||
− | *[[Masitinib ( | + | *[[Masitinib (AB-1010)]] |
− | *[[ | + | *[[MCARH-109]] |
− | *[[ | + | *[[Mezigdomide (BMS-986348)]] |
− | *[[ | + | *[[Milataxel (TL-139)]] |
− | *[[Mocetinostat ( | + | *[[MK-2206]] |
− | *[[ | + | *[[Mocetinostat (MGCD-0103)]] |
− | + | *[[Motesanib (AMG-706)]] | |
− | *[[ | + | |
+ | ==N== | ||
+ | *[[Nolatrexed (Thymitaq)]] | ||
==O== | ==O== | ||
− | + | *[[Oblimersen (Genasense)]] | |
− | |||
− | |||
− | |||
*[[Olaptesed pegol (NOX-A12)]] | *[[Olaptesed pegol (NOX-A12)]] | ||
*[[Onartuzumab (MetMAb)]] | *[[Onartuzumab (MetMAb)]] | ||
− | *[[Oprozomib (ONX 0912)]] | + | *[[Oprozomib (ONX-0912)]] |
*[[Orteronel (TAK-700)]] | *[[Orteronel (TAK-700)]] | ||
− | *[[Osocimab (BAY 1213790)]] | + | *[[Osocimab (BAY-1213790)]] |
*[[Otlertuzumab (TRU-016)]] | *[[Otlertuzumab (TRU-016)]] | ||
==P== | ==P== | ||
− | + | *[[Patritumab deruxtecan (U3-1402)]] | |
− | |||
− | |||
− | |||
*[[Pentraxin 2 (PRM-151)]] | *[[Pentraxin 2 (PRM-151)]] | ||
*[[Perifosine (KRX-0401)]] | *[[Perifosine (KRX-0401)]] | ||
Line 781: | Line 712: | ||
*[[Pictilisib (GDC-0941)]] | *[[Pictilisib (GDC-0941)]] | ||
*[[Pidilizumab (CT-011)]] | *[[Pidilizumab (CT-011)]] | ||
− | *[[ | + | *[[Pimitespib (TAS-116)]] |
− | *[[ | + | *[[Pinatuzumab vedotin (DCDT-2980S)]] |
*[[Plinabulin (NPI-2358)]] | *[[Plinabulin (NPI-2358)]] | ||
− | *[[Pracinostat ( | + | *[[Pracinostat (SB-939)]] |
==Q== | ==Q== | ||
*[[Quisinostat (JNJ-26481585)]] | *[[Quisinostat (JNJ-26481585)]] | ||
− | |||
==R== | ==R== | ||
− | + | *[[Rebimastat (BMS-275291)]] | |
− | + | *[[Refametinib (BAY-869766)]] | |
− | |||
− | |||
− | *[[Refametinib (BAY 869766)]] | ||
*[[Reovirus (Reolysin)]] | *[[Reovirus (Reolysin)]] | ||
*[[Retaspimycin (IPI-504)]] | *[[Retaspimycin (IPI-504)]] | ||
− | *[[Ricolinostat (ACY-1215 | + | *[[Revumenib (SNDX-5613)]] |
− | *[[Ridaforolimus ( | + | *[[Rezvilutamide (SHR-3680)]] |
− | *[[Rilotumumab (AMG 102)]] | + | *[[Ricolinostat (ACY-1215)]] |
+ | *[[Ridaforolimus (AP-23573)]] | ||
+ | *[[Rilotumumab (AMG-102)]] | ||
+ | *[[Ripertamab (SCT-400)]] | ||
*[[Rociletinib (CO-1686)]] | *[[Rociletinib (CO-1686)]] | ||
− | |||
==S== | ==S== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Sapacitabine (CS-682)]] | *[[Sapacitabine (CS-682)]] | ||
− | *[[Sapanisertib ( | + | *[[Sapanisertib (MLN-0128)]] |
− | *[[Seliciclib ( | + | *[[Seliciclib (CYC-202)]] |
− | *[[Semuloparin ( | + | *[[Semuloparin (AVE-5026)]] |
*[[Spebrutinib (CC-292)]] | *[[Spebrutinib (CC-292)]] | ||
*[[Surufatinib (HMPL-012)]] | *[[Surufatinib (HMPL-012)]] | ||
− | |||
==T== | ==T== | ||
− | + | ||
− | + | *[[Tabalumab (LY-2127399)]] | |
− | + | *[[Tasadenoturev (DNX-2401)]] | |
− | + | *[[Telisotuzumab vedotin (ABBV-399)]] | |
− | *[[Tabalumab ( | + | *[[Tertomotide (GV-1001)]] |
− | *[[ | ||
− | *[[ | ||
− | *[[ | ||
*[[Tesetaxel (DJ-927)]] | *[[Tesetaxel (DJ-927)]] | ||
− | *[[Tesevatinib ( | + | *[[Tesevatinib (XL-647)]] |
*[[Tigatuzumab (CS-1008)]] | *[[Tigatuzumab (CS-1008)]] | ||
*[[Tipifarnib (Zarnestra)]] | *[[Tipifarnib (Zarnestra)]] | ||
− | *[[ | + | *[[Tirapazamine (Tirazone)]] |
− | *[[Tislelizumab ( | + | *[[Tislelizumab (Baizean)]] |
− | *[[Tivantinib (ARQ 197)]] | + | *[[Tivantinib (ARQ-197)]] |
*[[Tivozanib (AV-951)]] | *[[Tivozanib (AV-951)]] | ||
*[[Tosedostat (CHR-2797)]] | *[[Tosedostat (CHR-2797)]] | ||
− | *[[Trebananib (AMG 386)]] | + | *[[Trebananib (AMG-386)]] |
− | *[[ | + | *[[Tusamitamab ravtansine (SAR-408701)]] |
==U== | ==U== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
*[[UCART19]] | *[[UCART19]] | ||
==V== | ==V== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Vadastuximab talirine (SGN-CD33A)]] | *[[Vadastuximab talirine (SGN-CD33A)]] | ||
+ | *[[Vadimezan (AS-A404)]] | ||
*[[Varlilumab (CDX-1127)]] | *[[Varlilumab (CDX-1127)]] | ||
*[[Veliparib (ABT-888)]] | *[[Veliparib (ABT-888)]] | ||
*[[Veltuzumab (hA20)]] | *[[Veltuzumab (hA20)]] | ||
− | *[[Volasertib (BI 6727)]] | + | *[[Volasertib (BI-6727)]] |
− | *[[Vosaroxin (SNS 595)]] | + | *[[Vorasidenib (AG-881)]] |
− | *[[Voxtalisib ( | + | *[[Vorolanib (CM-082)]] |
+ | *[[Vosaroxin (SNS-595)]] | ||
+ | *[[Voxtalisib (XL-765)]] | ||
==Z== | ==Z== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Zandelisib (ME-401)]] | *[[Zandelisib (ME-401)]] | ||
+ | *[[Zolbetuximab (IMAB-362)]] | ||
=Supportive and other medications= | =Supportive and other medications= | ||
+ | ''This section contains supportive drugs that are either approved or investigational. Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound.'' | ||
+ | ==A== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
*[[Abciximab (ReoPro)]] | *[[Abciximab (ReoPro)]] | ||
*[[Acetaminophen (Tylenol)]] | *[[Acetaminophen (Tylenol)]] | ||
*[[Acetazolamide (Diamox)]] | *[[Acetazolamide (Diamox)]] | ||
*[[Acyclovir (Zovirax)]] | *[[Acyclovir (Zovirax)]] | ||
+ | *[[ADAMTS13, recombinant (Adzynma)]] | ||
*[[Alendronate (Fosamax)]] | *[[Alendronate (Fosamax)]] | ||
*[[Alizapride (Litican)]] | *[[Alizapride (Litican)]] | ||
Line 884: | Line 797: | ||
*[[Amoxicillin]] | *[[Amoxicillin]] | ||
*[[Anagrelide (Agrylin)]] | *[[Anagrelide (Agrylin)]] | ||
+ | *[[Andexanet alfa (Andexxa)]] | ||
*[[Anti-inhibitor coagulant complex (FEIBA NF)]] | *[[Anti-inhibitor coagulant complex (FEIBA NF)]] | ||
*[[Antithrombin III (human and recombinant)]] | *[[Antithrombin III (human and recombinant)]] | ||
Line 902: | Line 816: | ||
==B== | ==B== | ||
− | + | *[[Betibeglogene autotemcel (Zynteglo)]] | |
− | |||
− | |||
− | |||
*[[Betrixaban (Bevyxxa)]] | *[[Betrixaban (Bevyxxa)]] | ||
*[[Bismuth subsalicylate (Pepto-Bismol)]] | *[[Bismuth subsalicylate (Pepto-Bismol)]] | ||
Line 911: | Line 822: | ||
==C== | ==C== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Cangrelor (Kengreal)]] | *[[Cangrelor (Kengreal)]] | ||
*[[Calcium phosphate rinse (Caphosol)]] | *[[Calcium phosphate rinse (Caphosol)]] | ||
+ | *[[Caspofungin (Cancidas)]] | ||
*[[Cetirizine (Zyrtec)]] | *[[Cetirizine (Zyrtec)]] | ||
*[[Chlorpheniramine (Chlor-Trimeton)]] | *[[Chlorpheniramine (Chlor-Trimeton)]] | ||
Line 926: | Line 835: | ||
*[[Clodronate (Bonefos)]] | *[[Clodronate (Bonefos)]] | ||
*[[Clopidogrel (Plavix)]] | *[[Clopidogrel (Plavix)]] | ||
+ | *[[CM-313]] | ||
+ | *[[Concizumab (Alhemo)]] | ||
*[[Crizanlizumab (Adakveo)]] | *[[Crizanlizumab (Adakveo)]] | ||
*[[Cyanocobalamin (Vitamin B12)]] | *[[Cyanocobalamin (Vitamin B12)]] | ||
Line 932: | Line 843: | ||
==D== | ==D== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Dabigatran (Pradaxa)]] | *[[Dabigatran (Pradaxa)]] | ||
*[[Dalteparin (Fragmin)]] | *[[Dalteparin (Fragmin)]] | ||
Line 947: | Line 855: | ||
*[[Defibrotide (Defitelio)]] | *[[Defibrotide (Defitelio)]] | ||
*[[Denosumab (Xgeva)]] | *[[Denosumab (Xgeva)]] | ||
+ | **[[Denosumab-bddz (Wyost)]] | ||
*[[Desmopressin (DDAVP)]] | *[[Desmopressin (DDAVP)]] | ||
*[[Dexchlorpheniramine (Polaramine)]] | *[[Dexchlorpheniramine (Polaramine)]] | ||
Line 959: | Line 868: | ||
==E== | ==E== | ||
− | |||
− | |||
− | |||
− | |||
*[[Eculizumab (Soliris)]] | *[[Eculizumab (Soliris)]] | ||
+ | **[[Eculizumab-beke (Bekemv)]] | ||
+ | **[[Eculizumab-epys (Epysqli)]] | ||
*[[Edoxaban (Savaysa)]] | *[[Edoxaban (Savaysa)]] | ||
+ | *[[Efanesoctocog alfa (Altuviiio)]] | ||
+ | *[[Eflapegrastim (Rolvedon)]] | ||
*[[Eltrombopag (Promacta)]] | *[[Eltrombopag (Promacta)]] | ||
− | *[[Emicizumab | + | *[[Emicizumab (Hemlibra)]] |
*[[Enoxaparin (Lovenox)]] | *[[Enoxaparin (Lovenox)]] | ||
− | **[[Enoxaparin (Inhixa)]] | + | **[[Enoxaparin-inhi (Inhixa)]] |
*[[Epoetin alfa (Procrit)]] | *[[Epoetin alfa (Procrit)]] | ||
**[[Epoetin alfa-epbx (Retacrit)]] | **[[Epoetin alfa-epbx (Retacrit)]] | ||
− | **[[Epoetin alfa (Abseamed)]] | + | **[[Epoetin alfa-abse (Abseamed)]] |
− | **[[Epoetin alfa (Binocrit)]] | + | **[[Epoetin alfa-bino (Binocrit)]] |
− | **[[Epoetin alfa (Epoetin Alfa Hexal)]] | + | **[[Epoetin alfa-hexa (Epoetin Alfa Hexal)]] |
+ | *[[Epoetin theta (Biopoin)]] | ||
*[[Epoetin zeta (Eprex)]] | *[[Epoetin zeta (Eprex)]] | ||
− | **[[Epoetin zeta (Silapo)]] | + | **[[Epoetin zeta-reta (Retacrit)]] |
+ | **[[Epoetin zeta-sila (Silapo)]] | ||
*[[Eptifibatide (Integrilin)]] | *[[Eptifibatide (Integrilin)]] | ||
+ | *[[Etranacogene dezaparvovec (Hemgenix)]] | ||
+ | *[[Exagamglogene autotemcel (Casgevy)]] '''FDA approved on 2023-12-08''' | ||
==F== | ==F== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Factor VIIa, recombinant (NovoSeven RT)]] | *[[Factor VIIa, recombinant (NovoSeven RT)]] | ||
*[[Factor VIII, human]] | *[[Factor VIII, human]] | ||
Line 990: | Line 900: | ||
*[[Factor IX, recombinant, Fc fusion protein (Alprolix)]] | *[[Factor IX, recombinant, Fc fusion protein (Alprolix)]] | ||
*[[Factor X, human (Coagadex)]] | *[[Factor X, human (Coagadex)]] | ||
− | |||
*[[Factor XIII concentrate, human (Corifact)]] | *[[Factor XIII concentrate, human (Corifact)]] | ||
*[[Famciclovir (Famvir)]] | *[[Famciclovir (Famvir)]] | ||
*[[Famotidine (Pepcid)]] | *[[Famotidine (Pepcid)]] | ||
*[[Ferric carboxymaltose (Injectafer)]] | *[[Ferric carboxymaltose (Injectafer)]] | ||
+ | *[[Ferric derisomaltose (Monoferric)]] | ||
*[[Ferric gluconate (Ferrlecit)]] | *[[Ferric gluconate (Ferrlecit)]] | ||
*[[Ferrous sulfate (Feosol)]] | *[[Ferrous sulfate (Feosol)]] | ||
Line 1,001: | Line 911: | ||
*[[Filgrastim (Neupogen)]] | *[[Filgrastim (Neupogen)]] | ||
**[[Filgrastim-aafi (Nivestym)]] | **[[Filgrastim-aafi (Nivestym)]] | ||
+ | **[[Filgrastim-ayow (Releuko)]] | ||
**[[Filgrastim-sndz (Zarxio)]] | **[[Filgrastim-sndz (Zarxio)]] | ||
− | **[[Filgrastim (Accofil)]] | + | **[[Filgrastim-acco (Accofil)]] |
− | **[[Filgrastim (Filgrastim Hexal)]] | + | **[[Filgrastim-hexa (Filgrastim Hexal)]] |
− | **[[Filgrastim (Grastofil)]] | + | **[[Filgrastim-gras (Grastofil)]] |
− | **[[Filgrastim (Ratiograstim)]] | + | **[[Filgrastim-rati (Ratiograstim)]] |
− | **[[Filgrastim (Tevagrastim)]] | + | **[[Filgrastim-teva (Tevagrastim)]] |
*[[Finasteride (Proscar)]] | *[[Finasteride (Proscar)]] | ||
+ | *[[Fitusiran (ALN-AT3SC)]] | ||
*[[Fluconazole (Diflucan)]] | *[[Fluconazole (Diflucan)]] | ||
*[[Folic acid (Folate)]] | *[[Folic acid (Folate)]] | ||
*[[Fondaparinux (Arixtra)]] | *[[Fondaparinux (Arixtra)]] | ||
*[[Fosaprepitant (Emend for Injection)]] | *[[Fosaprepitant (Emend for Injection)]] | ||
+ | *[[Fosnetupitant (Arokaris)]] | ||
*[[Furosemide (Lasix)]] | *[[Furosemide (Lasix)]] | ||
==G== | ==G== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Glucarpidase (Voraxaze)]] | *[[Glucarpidase (Voraxaze)]] | ||
− | *[[Granisetron | + | *[[Granisetron]] |
− | |||
− | |||
==H== | ==H== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Haloperidol (Haldol)]] | *[[Haloperidol (Haldol)]] | ||
*[[Hematopoetic progenitor cells, cord blood (Hemacord)]] | *[[Hematopoetic progenitor cells, cord blood (Hemacord)]] | ||
==I== | ==I== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Ibandronate (Boniva)]] | *[[Ibandronate (Boniva)]] | ||
*[[Idarucizumab (Praxbind)]] | *[[Idarucizumab (Praxbind)]] | ||
*[[Indomethacin (Indocin)]] | *[[Indomethacin (Indocin)]] | ||
+ | *[[Iptacopan (Fabhalta)]] '''FDA approved 2023-12-05''' | ||
*[[Iron dextran (INFeD)]] | *[[Iron dextran (INFeD)]] | ||
*[[Iron sucrose (Venofer)]] | *[[Iron sucrose (Venofer)]] | ||
Line 1,045: | Line 948: | ||
==L== | ==L== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Lactulose]] | *[[Lactulose]] | ||
*[[Lamivudine (Epivir)]] | *[[Lamivudine (Epivir)]] | ||
Line 1,054: | Line 954: | ||
*[[Lenograstim (Granocyte)]] | *[[Lenograstim (Granocyte)]] | ||
*[[Lepirudin (Refludan)]] '''discontinued''' | *[[Lepirudin (Refludan)]] '''discontinued''' | ||
+ | *[[Letermovir (Prevymis)]] | ||
*[[Levofloxacin (Levaquin)]] | *[[Levofloxacin (Levaquin)]] | ||
*[[L-glutamine (Endari)]] | *[[L-glutamine (Endari)]] | ||
− | *[[Lipefilgrastim ( | + | *[[Lipefilgrastim (Lonquex)]] |
*[[Loperamide (Imodium)]] | *[[Loperamide (Imodium)]] | ||
*[[Lorazepam (Ativan)]] | *[[Lorazepam (Ativan)]] | ||
+ | *[[Lovotibeglogene autotemcel (Lyfgenia)]] '''FDA approved on 2023-12-08''' | ||
*[[Luspatercept (Reblozyl)]] | *[[Luspatercept (Reblozyl)]] | ||
*[[Lusutrombopag (Mulpleta)]] | *[[Lusutrombopag (Mulpleta)]] | ||
==M== | ==M== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Mannitol]] | *[[Mannitol]] | ||
Line 1,073: | Line 972: | ||
*[[Methyltesterone (Android)]] | *[[Methyltesterone (Android)]] | ||
*[[Metoclopramide (Reglan)]] | *[[Metoclopramide (Reglan)]] | ||
− | *[[Mitapivat ( | + | *[[Mitapivat (Pyrukynd)]] |
+ | *[[Motixafortide (Aphexda)]] '''FDA approved 2023-09''' | ||
*[[Mycophenolate mofetil (CellCept)]] | *[[Mycophenolate mofetil (CellCept)]] | ||
==N== | ==N== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Nabilone (Cesamet)]] | *[[Nabilone (Cesamet)]] | ||
*[[Netupitant and palonosetron (Akynzeo)]] | *[[Netupitant and palonosetron (Akynzeo)]] | ||
+ | *[[Nonacog beta pegol (Refixia)]] | ||
==O== | ==O== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Olanzapine (Zyprexa)]] | *[[Olanzapine (Zyprexa)]] | ||
*[[Omeprazole (Prilosec)]] | *[[Omeprazole (Prilosec)]] | ||
+ | *[[Omidubicel (Omisirge)]] '''FDA approved 2023-04-17''' | ||
*[[Ondansetron (Zofran)]] | *[[Ondansetron (Zofran)]] | ||
*[[Oprelvekin (Neumega)]] | *[[Oprelvekin (Neumega)]] | ||
==P== | ==P== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Palifermin (Kepivance)]] | *[[Palifermin (Kepivance)]] | ||
Line 1,109: | Line 1,002: | ||
**[[Pegfilgrastim-bmez (Ziextenzo)]] | **[[Pegfilgrastim-bmez (Ziextenzo)]] | ||
**[[Pegfilgrastim-cbqv (Udenyca)]] | **[[Pegfilgrastim-cbqv (Udenyca)]] | ||
+ | **[[Pegfilgrastim-fpgk (Stimufend)]] | ||
**[[Pegfilgrastim-jmdb (Fulphila)]] | **[[Pegfilgrastim-jmdb (Fulphila)]] | ||
− | **[[Pegfilgrastim (Cegfila)]] | + | **[[Pegfilgrastim-cegf (Cegfila)]] |
− | **[[Pegfilgrastim (Grasustek)]] | + | **[[Pegfilgrastim-gras (Grasustek)]] |
− | **[[Pegfilgrastim (Pelgraz)]] | + | **[[Pegfilgrastim-pbbk (Fylnetra)]] |
− | **[[Pegfilgrastim (Pelmeg)]] | + | **[[Pegfilgrastim-pelg (Pelgraz)]] |
+ | **[[Pegfilgrastim-pelm (Pelmeg)]] | ||
+ | **[[Pegfilgrastim-stim (Stimufend)]] | ||
*[[Penicillin V]] | *[[Penicillin V]] | ||
*[[Pentamidine (Nebupent)]] | *[[Pentamidine (Nebupent)]] | ||
Line 1,124: | Line 1,020: | ||
*[[Promethazine (Phenergan)]] | *[[Promethazine (Phenergan)]] | ||
*[[Protamine sulfate]] | *[[Protamine sulfate]] | ||
+ | *[[Protein C, human (Ceprotin)]] | ||
*[[Prothrombin Complex Concentrate, human]] | *[[Prothrombin Complex Concentrate, human]] | ||
Line 1,131: | Line 1,028: | ||
==R== | ==R== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
*[[Rabeprazole (Aciphex)]] | *[[Rabeprazole (Aciphex)]] | ||
*[[Raloxifene (Evista)]] | *[[Raloxifene (Evista)]] | ||
Line 1,141: | Line 1,033: | ||
*[[Ranitidine (Zantac)]] | *[[Ranitidine (Zantac)]] | ||
*[[Rasburicase (Elitek)]] | *[[Rasburicase (Elitek)]] | ||
+ | *[[Remestemcel-L (Prochymal)]] | ||
*[[Rho(D) immune globulin (RhoGAM)]] | *[[Rho(D) immune globulin (RhoGAM)]] | ||
*[[Rilzabrutinib (PRN-1008)]] | *[[Rilzabrutinib (PRN-1008)]] | ||
Line 1,147: | Line 1,040: | ||
*[[Rolapitant (Varubi)]] | *[[Rolapitant (Varubi)]] | ||
*[[Romiplostim (Nplate)]] | *[[Romiplostim (Nplate)]] | ||
+ | *[[Rusfertide (PTG-300)]] | ||
==S== | ==S== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Sargramostim (Leukine)]] | *[[Sargramostim (Leukine)]] | ||
*[[Scopolamine (Scopoderm)]] | *[[Scopolamine (Scopoderm)]] | ||
Line 1,158: | Line 1,049: | ||
*[[Siltuximab (Sylvant)]] | *[[Siltuximab (Sylvant)]] | ||
*[[Sirolimus (Rapamune)]] | *[[Sirolimus (Rapamune)]] | ||
+ | *[[Sodium thiosulfate (Pedmark)]] | ||
+ | *[[Sutimlimab (Enjaymo)]] | ||
==T== | ==T== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Tacrolimus (Prograf)]] | *[[Tacrolimus (Prograf)]] | ||
*[[Tbo-filgrastim (Granix)]] | *[[Tbo-filgrastim (Granix)]] | ||
+ | *[[Telotristat (Xermelo)]] | ||
*[[Ticagrelor (Brilinta)]] | *[[Ticagrelor (Brilinta)]] | ||
− | *[[ | + | *[[Ticlopidine (Ticlid)]] |
*[[Tinzaparin (Innohep)]] | *[[Tinzaparin (Innohep)]] | ||
*[[Tirofiban (Aggrastat)]] | *[[Tirofiban (Aggrastat)]] | ||
*[[Tocilizumab (Actemra)]] | *[[Tocilizumab (Actemra)]] | ||
+ | **[[Tocilizumab-aazg (Tyenne)]] | ||
+ | **[[Tocilizumab-bavi (Tofidence)]] | ||
*[[Tofacitinib (Xeljanz)]] | *[[Tofacitinib (Xeljanz)]] | ||
*[[Tranexamic acid (Cyklokapron)]] | *[[Tranexamic acid (Cyklokapron)]] | ||
+ | *[[Trilaciclib (Cosela)]] | ||
*[[Trimethoprim-Sulfamethoxazole (Bactrim DS)]] | *[[Trimethoprim-Sulfamethoxazole (Bactrim DS)]] | ||
*[[Tropisetron (Navoban)]] | *[[Tropisetron (Navoban)]] | ||
Line 1,181: | Line 1,075: | ||
==V== | ==V== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Valacyclovir (Valtrex)]] | *[[Valacyclovir (Valtrex)]] | ||
*[[Valganciclovir (Valcyte)]] | *[[Valganciclovir (Valcyte)]] | ||
*[[Valoctocogene roxaparvovec (AAV5-hFVIII-SQ)]] | *[[Valoctocogene roxaparvovec (AAV5-hFVIII-SQ)]] | ||
*[[Valproate (Depakote)]] | *[[Valproate (Depakote)]] | ||
+ | *[[Verbrinacogene setparvovec (FLT-180a)]] | ||
*[[von Willebrand factor and factor VIII complex, human]] | *[[von Willebrand factor and factor VIII complex, human]] | ||
*[[von Willebrand factor, recombinant]] | *[[von Willebrand factor, recombinant]] | ||
+ | *[[Vonoprazan (Takecab)]] | ||
*[[Vorapaxar (Zontivity)]] | *[[Vorapaxar (Zontivity)]] | ||
*[[Voriconazole (Vfend)]] | *[[Voriconazole (Vfend)]] | ||
==W== | ==W== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Warfarin (Coumadin)]] | *[[Warfarin (Coumadin)]] | ||
Line 1,206: | Line 1,096: | ||
=By Category= | =By Category= | ||
− | ''Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is | + | ''Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is an ongoing process so not all of these links are active or current).'' |
==[[:Category:REMS_program|Drugs in a REMS program]]== | ==[[:Category:REMS_program|Drugs in a REMS program]]== | ||
==Cytotoxic Chemotherapy== | ==Cytotoxic Chemotherapy== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Alkylating agents|Alkylating agents]] | *[[:Category:Alkylating agents|Alkylating agents]] | ||
Line 1,230: | Line 1,117: | ||
==[[:Category:Kinase inhibitors|Kinase inhibitors]]== | ==[[:Category:Kinase inhibitors|Kinase inhibitors]]== | ||
− | + | ||
− | |||
− | |||
− | |||
<div style="column-count:2;-moz-column-count:2;-webkit-column-count:2"> | <div style="column-count:2;-moz-column-count:2;-webkit-column-count:2"> | ||
*[[:Category:AKT1 inhibitors|AKT1 inhibitors]] | *[[:Category:AKT1 inhibitors|AKT1 inhibitors]] | ||
Line 1,267: | Line 1,151: | ||
==[[:Category:Endocrine therapeutic|Endocrine therapy]]== | ==[[:Category:Endocrine therapeutic|Endocrine therapy]]== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Antiandrogens|Antiandrogens]] | *[[:Category:Antiandrogens|Antiandrogens]] | ||
Line 1,289: | Line 1,170: | ||
==Biologics== | ==Biologics== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Antibody medications|Antibody medications]] | *[[:Category:Antibody medications|Antibody medications]] | ||
Line 1,303: | Line 1,181: | ||
==Supportive Medications== | ==Supportive Medications== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Antibacterials|Antibacterials]] | *[[:Category:Antibacterials|Antibacterials]] | ||
Line 1,326: | Line 1,201: | ||
==[[:Category:Hematology medications|Benign Hematology Medications]]== | ==[[:Category:Hematology medications|Benign Hematology Medications]]== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Anticoagulants|Anticoagulants]] | *[[:Category:Anticoagulants|Anticoagulants]] | ||
Line 1,348: | Line 1,220: | ||
==[[:Category:Hematopoietic growth factors|Hematopoietic Growth Factors]]== | ==[[:Category:Hematopoietic growth factors|Hematopoietic Growth Factors]]== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Erythrocyte growth factors|Erythrocyte growth factors]] | *[[:Category:Erythrocyte growth factors|Erythrocyte growth factors]] | ||
Line 1,358: | Line 1,227: | ||
==Miscellaneous== | ==Miscellaneous== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:REMS_program|Drugs in a REMS program]] | *[[:Category:REMS_program|Drugs in a REMS program]] | ||
Line 1,370: | Line 1,236: | ||
==Medications by Condition== | ==Medications by Condition== | ||
− | + | ||
− | |||
− | |||
− | |||
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | <div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | ||
*[[:Category:B-cell acute lymphoblastic leukemia medications|Acute lymphocytic leukemia medications]] | *[[:Category:B-cell acute lymphoblastic leukemia medications|Acute lymphocytic leukemia medications]] | ||
Line 1,380: | Line 1,243: | ||
*[[:Category:Anal cancer medications|Anal cancer medications]] | *[[:Category:Anal cancer medications|Anal cancer medications]] | ||
*[[:Category:Anaplastic large cell lymphoma medications|Anaplastic large cell lymphoma medications]] | *[[:Category:Anaplastic large cell lymphoma medications|Anaplastic large cell lymphoma medications]] | ||
− | |||
*[[:Category:Bladder cancer medications|Bladder cancer medications]] | *[[:Category:Bladder cancer medications|Bladder cancer medications]] | ||
*[[:Category:Bone cancer medications |Bone cancer medications]] | *[[:Category:Bone cancer medications |Bone cancer medications]] | ||
Line 1,386: | Line 1,248: | ||
*[[:Category:Burkitt lymphoma medications|Burkitt lymphoma medications]] | *[[:Category:Burkitt lymphoma medications|Burkitt lymphoma medications]] | ||
*[[:Category:Cancer of unknown primary medications |Cancer of unknown primary medications]] | *[[:Category:Cancer of unknown primary medications |Cancer of unknown primary medications]] | ||
− | *[[:Category: | + | *[[:Category:Castleman disease medications|Castleman disease medications]] |
*[[:Category:Central nervous system (CNS) cancer medications|Central nervous system (CNS) cancer medications]] | *[[:Category:Central nervous system (CNS) cancer medications|Central nervous system (CNS) cancer medications]] | ||
*[[:Category:CNS lymphoma medications|Central nervous system (CNS) lymphoma medications]] | *[[:Category:CNS lymphoma medications|Central nervous system (CNS) lymphoma medications]] | ||
*[[:Category:Cervical cancer medications|Cervical cancer medications]] | *[[:Category:Cervical cancer medications|Cervical cancer medications]] | ||
*[[:Category:Chronic lymphocytic leukemia medications|Chronic lymphocytic leukemia (CLL/SLL) medications]] | *[[:Category:Chronic lymphocytic leukemia medications|Chronic lymphocytic leukemia (CLL/SLL) medications]] | ||
− | *[[:Category:Chronic | + | *[[:Category:Chronic myeloid leukemia medications|Chronic myeloid leukemia (CML) medications]] |
− | *[[:Category:Chronic myelomonocytic leukemia medications|Chronic myelomonocytic leukemia medications]] | + | *[[:Category:Chronic myelomonocytic leukemia medications|Chronic myelomonocytic leukemia (CMML) medications]] |
*[[:Category:Colon cancer medications|Colon cancer medications]] | *[[:Category:Colon cancer medications|Colon cancer medications]] | ||
+ | *[[:Category:Colorectal cancer medications|Colorectal cancer (CRC) medications]] | ||
+ | *[[:Category:Cutaneous basal cell carcinoma medications|Cutaneous BCC medications]] | ||
+ | *[[:Category:Cutaneous squamous cell carcinoma medications|Cutaneous SCC medications]] | ||
*[[:Category:Cutaneous T-cell lymphoma medications|Cutaneous T-cell lymphoma medications]] | *[[:Category:Cutaneous T-cell lymphoma medications|Cutaneous T-cell lymphoma medications]] | ||
*[[:Category:Diffuse large B-cell lymphoma medications|Diffuse large B-cell lymphoma medications]] | *[[:Category:Diffuse large B-cell lymphoma medications|Diffuse large B-cell lymphoma medications]] | ||
Line 1,445: | Line 1,310: | ||
==[[:Category:Routed medications|Medications by Route of Administration]]== | ==[[:Category:Routed medications|Medications by Route of Administration]]== | ||
− | + | ||
− | |||
− | |||
− | |||
*[[:Category:Intra-arterial medications|Intraarterial (IA) medications]] | *[[:Category:Intra-arterial medications|Intraarterial (IA) medications]] | ||
Line 1,459: | Line 1,321: | ||
*[[:Category:Subcutaneous medications|Subcutaneous (SC) medications]] | *[[:Category:Subcutaneous medications|Subcutaneous (SC) medications]] | ||
− | ==Medications by Year of Approval== | + | ==Medications by FDA Year of Approval== |
− | + | ||
− | |||
− | |||
− | |||
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | <div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | ||
*[[:Category:FDA approved in 1939|FDA approved in 1939]] | *[[:Category:FDA approved in 1939|FDA approved in 1939]] | ||
Line 1,535: | Line 1,394: | ||
*[[:Category:FDA approved in 2018|FDA approved in 2018]] | *[[:Category:FDA approved in 2018|FDA approved in 2018]] | ||
*[[:Category:FDA approved in 2019|FDA approved in 2019]] | *[[:Category:FDA approved in 2019|FDA approved in 2019]] | ||
+ | *[[:Category:FDA approved in 2020|FDA approved in 2020]] | ||
+ | *[[:Category:FDA approved in 2021|FDA approved in 2021]] | ||
+ | *[[:Category:FDA approved in 2022|FDA approved in 2022]] | ||
+ | *[[:Category:FDA approved in 2023|FDA approved in 2023]] | ||
+ | *[[:Category:FDA approved in 2024|FDA approved in 2024]] | ||
</div> | </div> | ||
=Interesting and Helpful Links= | =Interesting and Helpful Links= | ||
− | + | ||
− | |||
− | |||
− | |||
*[[Antidepressants and other psychiatric medications in cancer care]] | *[[Antidepressants and other psychiatric medications in cancer care]] | ||
Line 1,548: | Line 1,409: | ||
*[https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society (ASCO/ONS) Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology] | *[https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society (ASCO/ONS) Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology] | ||
*[http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p Chemotherapy Administration Sequence]<ref>Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. [http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p link to original article]</ref> - with chemotherapy sequencing chart | *[http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p Chemotherapy Administration Sequence]<ref>Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. [http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p link to original article]</ref> - with chemotherapy sequencing chart | ||
− | *[https:// | + | *[https://doi.org/10.1111/j.1743-7563.2010.01321.x The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy.] [https://pubmed.ncbi.nlm.nih.gov/20887505/ PubMed] |
*[https://crediblemeds.org/ CredibleMeds.org] - lists of QT-prolonging drugs; requires free registration to see full list | *[https://crediblemeds.org/ CredibleMeds.org] - lists of QT-prolonging drugs; requires free registration to see full list | ||
*[http://www.accessdata.fda.gov/scripts/drugshortages/default.cfm FDA drug shortages list] | *[http://www.accessdata.fda.gov/scripts/drugshortages/default.cfm FDA drug shortages list] | ||
Line 1,554: | Line 1,415: | ||
*[http://dailymed.nlm.nih.gov/dailymed/index.cfm DailyMed] - a comprehensive NLM portal to all FDA-approved drugs | *[http://dailymed.nlm.nih.gov/dailymed/index.cfm DailyMed] - a comprehensive NLM portal to all FDA-approved drugs | ||
*[http://www.accessdata.fda.gov/scripts/cder/drugsatfda/ Drugs@FDA] - the main portal into the FDA drug database | *[http://www.accessdata.fda.gov/scripts/cder/drugsatfda/ Drugs@FDA] - the main portal into the FDA drug database | ||
− | *[ | + | *[https://www.cancer.gov/drugdictionary The NCI Drug Dictionary] - an extensive resource with most antineoplastics (approved and in clinical trials) listed |
*[http://blogs.sciencemag.org/pipeline/ In the Pipeline] - a blog from a veteran of the pharmaceutical industry, Derek Lowe. General but much is cancer-relevant. The [http://www.pipeline.corante.com/ old home] of this blog is no longer active. | *[http://blogs.sciencemag.org/pipeline/ In the Pipeline] - a blog from a veteran of the pharmaceutical industry, Derek Lowe. General but much is cancer-relevant. The [http://www.pipeline.corante.com/ old home] of this blog is no longer active. | ||
*[[Steroid conversions]] | *[[Steroid conversions]] |
Latest revision as of 11:56, 5 July 2024
Guidelines
Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any guideline published 5+ years ago to be for historical purposes, only.
Other interesting and helpful links can be found by clicking the link.
Chemotherapy safety standards
- 2020: Dillmon et al. Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards PubMed
- 2019: Celano et al. Safe handling of hazardous drugs: ASCO standards PubMed
- 2016: Neuss et al. 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards, including standards for pediatric oncology
- 2010: Carrington et al. The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy PubMed
Dose adjustments
- 2021: Griggs et al. Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update
- 2012: Griggs et al. Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline[1]
Antimicrobials
Growth factors
- 2015: Update of ASCO Clinical Practice Guideline recommendations for the use of WBC growth factors[2]
Approved antineoplastics
This section contains anticancer drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound. For drugs first approved within the current or prior calendar years, the date of initial approval is also provided here.
A
- Abarelix (Plenaxis)
- Abemaciclib (Verzenio)
- Abiraterone (Zytiga)
- Acalabrutinib (Calquence)
- Aclarubicin (Aclacinomycin)
- Adagrasib (Krazati)
- Afatinib (Gilotrif)
- Aldesleukin (Proleukin)
- Alectinib (Alecensa)
- Alemtuzumab (Campath)
- Alitretinoin (Panretin)
- All-trans retinoic acid (ATRA)
- Alpelisib (Piqray)
- Altretamine (Hexalen)
- Alvocidib (Flavopiridol)
- Amifostine (Ethyol)
- Aminoglutethimide (Cytadren)
- Amivantamab (Rybrevant)
- Amrubicin (Calsed)
- Amsacrine (Amsidine)
- Anastrozole (Arimidex)
- Ancestim (Stemgen)
- Anlotinib (Fukewei)
- Apalutamide (Erleada)
- Apatinib (Aitan)
- Arsenic trioxide (Trisenox)
- Asciminib (Scemblix)
- Asparaginase Erwinia chrysanthemi (Erwinaze)
- Atezolizumab (Tecentriq)
- Aumolertinib (Amelie)
- Avapritinib (Ayvakit)
- Avelumab (Bavencio)
- Axicabtagene ciloleucel (Yescarta)
- Axitinib (Inlyta)
- Azacitidine (Onureg)
- Azacitidine (Vidaza)
B
- BCG vaccine
- Belantamab mafodotin (Blenrep)
- Belinostat (Beleodaq)
- Belotecan (Camptobell)
- Belumosudil (Rezurock)
- Belzutifan (Welireg)
- Bendamustine
- Benralizumab (Fasenra)
- Bevacizumab (Avastin)
- Bexarotene (Targretin)
- Bicalutamide (Casodex)
- Binimetinib (Mektovi)
- Bleomycin (Blenoxane)
- Blinatumomab (Blincyto)
- Borofalan-10B (Steboronine)
- Bortezomib (Velcade)
- Bosutinib (Bosulif)
- Brentuximab vedotin (Adcetris)
- Brexucabtagene autoleucel (Tecartus)
- Brigatinib (Alunbrig)
- Buserelin (Suprefact)
- Busulfan (Myleran)
C
- Cabazitaxel (Jevtana)
- Cabozantinib (Cabometyx)
- Cabozantinib (Cometriq)
- Calaspargase (Asparlas)
- Camrelizumab (AiRuiKa)
- Capecitabine (Xeloda)
- Capivasertib (Truqap) FDA approved 2023-11-16
- Caplacizumab (Cablivi)
- Capmatinib (Tabrecta)
- Carboplatin (Paraplatin)
- Carfilzomib (Kyprolis)
- Carmofur (HCFU)
- Carmustine (BCNU)
- Carmustine wafer, polifeprosan 20 (Gliadel)
- Cemiplimab (Libtayo)
- Ceritinib (Zykadia)
- Cetuximab (Erbitux)
- Chidamide (Epidaza)
- Chlorambucil (Leukeran)
- Chlorozotocin (DCNU)
- Ciltacabtagene autoleucel (Carvykti)
- Cisplatin (Platinol)
- Cladribine (Leustatin)
- Clofarabine (Clolar)
- Cobimetinib (Cotellic)
- Copanlisib (Aliqopa)
- Cortisone
- Crizotinib (Xalkori)
- Cyclophosphamide (Cytoxan)
- Cyproterone acetate (Androcur)
- Cytarabine (Ara-C)
- Cytarabine and daunorubicin liposomal (Vyxeos)
- Cytarabine liposomal (DepoCyt)
D
- Dabrafenib (Tafinlar)
- Dacarbazine (DTIC)
- Dacomitinib (Vizimpro)
- Dactinomycin (Cosmegen)
- Daratumumab (Darzalex)
- Daratumumab and hyaluronidase (Darzalex Faspro)
- Daratumumab and vorhyaluronidase (Darzquro)
- Darinaparsin (Darvias)
- Darolutamide (Nubeqa)
- Dasatinib (Sprycel)
- Daunorubicin (Cerubidine)
- Decitabine (Dacogen)
- Decitabine and cedazuridine (Inqovi)
- Degarelix (Firmagon)
- Dexamethasone (Decadron)
- Dinutuximab (Unituxin)
- Dinutuximab beta (Qarziba)
- Docetaxel (Taxotere)
- Donafenib (Zepsun)
- Dostarlimab (Jemperli)
- Doxifluridine (Didox)
- Doxorubicin (Adriamycin)
- Durvalumab (Imfinzi)
- Dutasteride (Avodart)
- Duvelisib (Copiktra)
E
- Eflornithine (Iwilfin) FDA approved 2023-12-13
- Elacestrant (Orserdu) FDA approved 2023-01-27
- Elotuzumab (Empliciti)
- Elranatamab (Elrexfio) FDA approved on 2023-08-14
- Emapalumab (Gamifant)
- Enasidenib (Idhifa)
- Encorafenib (Braftovi)
- Enfortumab vedotin (Padcev)
- Ensartinib (Ensacove)
- Entrectinib (Rozlytrek)
- Envafolimab (Enweida)
- Enzalutamide (Xtandi)
- Epcoritamab (Epkinly) FDA approved 2023-05-19
- Epirubicin (Ellence)
- Erdafitinib (Balversa)
- Eribulin (Halaven)
- Erlotinib (Tarceva)
- Estradiol
- Estramustine (Emcyt)
- Etoposide (Vepesid)
- Everolimus (Afinitor)
- Exemestane (Aromasin)
F
- Fadrozole (Afema)
- Fedratinib (Inrebic)
- Fluorouracil (5-FU)
- Fludarabine (Fludara)
- Flumatinib (Xinfu)
- Flutamide (Eulexin)
- Leucovorin (Folinic acid)
- Forodesine (Fodosine)
- Fostamatinib (Tavalisse)
- Fotemustine (Muphoran)
- Fruquintinib (Elunate)
- Fulvestrant (Faslodex)
- Furmonertinib (Ivesa)
- Futibatinib (Lytgobi)
G
- Gallium Ga 68 gozetotide (Locametz)
- Gefitinib (Iressa)
- Gemcitabine (Gemzar)
- Gemtuzumab ozogamicin (Mylotarg)
- Gilteritinib (Xospata)
- Glasdegib (Daurismo)
- Glofitamab (Columvi) FDA approved 2023-06-15
- Goserelin (Zoladex)
H
- Heptaplatin (SunPla)
- Histamine dihydrochloride (Ceplene)
- Histrelin (Vantas)
- Hydrocortisone (Cortef)
- Hydroxyurea (Hydrea)
I
- Ibritumomab tiuxetan (Zevalin)
- Ibrutinib (Imbruvica)
- Icotinib (Conmana)
- Idarubicin (Idamycin)
- Idecabtagene vicleucel (Abecma)
- Idelalisib (Zydelig)
- Ifosfamide (Ifex)
- Imatinib (Gleevec)
- Imetelstat (Rytelo) FDA approved 2024-06-06
- Infigratinib (Truseltiq)
- Inotuzumab ozogamicin (Besponsa)
- Interferon alfa-2a (Roferon-A)
- Interferon alfa-2b (Intron-A)
- Interferon gamma-1a (Imunomax-γ)
- Interferon gamma-1b (Actimmune)
- Iobenguane I 131 (Azedra)
- Iodine-131
- Ipilimumab (Yervoy)
- Irinotecan (Camptosar)
- Irinotecan liposome (Onivyde)
- Isatuximab (Sarclisa)
- Isotretinoin (Accutane)
- Ivosidenib (Tibsovo)
- Ixabepilone (Ixempra)
- Ixazomib (Ninlaro)
K
L
- Lanreotide (Somatuline)
- Lanreotide LAR (Somatuline Depot)
- Lapatinib (Tykerb)
- Larotrectinib (Vitrakvi)
- Lasofoxifene (Fablyn)
- Lenalidomide (Revlimid)
- Lenvatinib (Lenvima)
- Letrozole (Femara)
- Leuprolide (Lupron)
- Levoleucovorin (Fusilev)
- Lifileuecel (Contego) FDA approved 2024-02-16
- Lisocabtagene maraleucel (Breyanzi)
- Lobaplatin (D-19466)
- Lomustine (CCNU)
- Loncastuximab tesirine (Zynlonta)
- Lorlatinib (Lorbrena)
- Lurbinectedin (Zepzelca)
- Lutetium Lu 177 dotatate (Lutathera)
- Lutetium Lu 177 vipivotide tetraxetan (Pluvicto)
M
- Margetuximab (Margenza)
- Mechlorethamine (Mustargen)
- Medroxyprogesterone acetate (MPA)
- Megestrol (Megace)
- Melphalan (Alkeran)
- Melphalan for Injection-Hepatic Delivery System (Hepzato Kit) FDA approved on 2023-08-14
- Mepolizumab (Nucala)
- Mercaptopurine (6-MP)
- Methotrexate (MTX)
- Methoxsalen (Uvadex)
- Methylprednisolone (Solumedrol)
- Midostaurin (Rydapt)
- Mifamurtide (Mepact)
- Miriplatin (Miripla)
- Mirvetuximab soravtansine (Elahere)
- Mitomycin pyelocalyceal (Jelmyto)
- Mitomycin (Mutamycin)
- Mitotane (Lysodren)
- Mitoxantrone (Novantrone)
- Mobocertinib (Exkivity)
- Mogamulizumab (Poteligeo)
- Momelotinib (Ojjaara) FDA approved 2023-09-15
- Mosunetuzumab (Lunsumio)
- Moxetumomab pasudotox (Lumoxiti)
N
- Nadofaragene firadenovec (Adstiladrin)
- Naxitamab (Danyelza)
- Necitumumab (Portrazza)
- Nedaplatin (Aqupla)
- Nelarabine (Arranon)
- Neratinib (Nerlynx)
- Nilotinib (Tasigna)
- Nilutamide (Nilandron)
- Nimotuzumab (Theraloc)
- Nimustine (ACNU)
- Nintedanib (Vargatef)
- Niraparib (Zejula)
- Niraparib and abiraterone (Akeega) FDA approved 2023-08-11
- Nirogacestat (Ogsiveo) FDA approved 2023-11-27
- Nivolumab (Opdivo)
- Nivolumab and relatlimab (Opdualag)
- Nogapendekin alfa inbakicept (Anktiva) FDA approved 2024-04-22
- Non-pegylated liposomal doxorubicin (Myocet)
- Norethandrolone (Nilevar)
- NovoTTF-100A system (Optune)
O
- Obinutuzumab (Gazyva)
- Octreotide (Sandostatin)
- Octreotide LAR (Sandostatin LAR)
- Ofatumumab (Arzerra)
- Olaparib (Lynparza)
- Olutasidenib (Rezlidhia)
- Olverembatinib (HQP-1351)
- Omacetaxine (Synribo)
- Osimertinib (Tagrisso)
- Oxaliplatin (Eloxatin)
P
- Paclitaxel (Taxol)
- Paclitaxel, nanoparticle albumin-bound (Abraxane)
- Paclitaxel, polymeric micelle-bound (Genexol-PM)
- Pacritinib (Vonjo)
- Padeliporfin (Tookad)
- Palbociclib (Ibrance)
- Panitumumab (Vectibix)
- Panobinostat (Farydak)
- Pazopanib (Votrient)
- Pegaspargase (Oncaspar)
- Peginterferon alfa-2a (Pegasys)
- Peginterferon alfa-2b (Sylatron)
- Pegylated liposomal doxorubicin (Doxil)
- Pembrolizumab (Keytruda)
- Pemetrexed (Alimta)
- Pemigatinib (Pemazyre)
- Penpulimab (Anniko)
- Pentostatin (Nipent)
- Pertuzumab (Perjeta)
- Pertuzumab and Trastuzumab hyaluronidase (Phesgo)
- Pexidartinib (Turalio)
- Pipobroman (Vercyte)
- Pirarubicin (THP)
- Pirtobrutinib (Jaypirca) FDA approved 2023-01-27
- Pixantrone (Pixuvri)
- Polatuzumab vedotin (Polivy)
- Pomalidomide (Pomalyst)
- Ponatinib (Iclusig)
- Porfimer (Photofrin)
- Pralatrexate (Folotyn)
- Pralsetinib (Gavreto)
- Prednisone (Sterapred)
- Prednisolone (Millipred)
- Procarbazine (Matulane)
- Pyrotinib (Irene)
Q
R
- Racotumomab (Vaxira)
- Radium-223 (Xofigo)
- Radotinib (Supect)
- Raltitrexed (Tomudex)
- Ramucirumab (Cyramza)
- Ranimustine (Cymerin)
- Ravulizumab (Ultomiris)
- Realgar-Indigo naturalis formulation
- Regorafenib (Stivarga)
- Relugolix (Orgovyx)
- Repotrectinib (Augtyro) FDA approved 2023-11-15
- Retifanlimab (Zynyz) FDA approved 2023-03-22
- Ribociclib (Kisqali)
- Ripretinib (Qinlock)
- Rituximab (Rituxan)
- Rituximab and hyaluronidase human (Rituxan Hycela)
- Romidepsin (Istodax)
- Ropeginterferon alfa-2b (Besremi)
- Rucaparib (Rubraca)
- Ruxolitinib (Jakafi)
S
- Sacituzumab govitecan (Trodelvy)
- Samarium-153 (Quadramet)
- Selinexor (Xpovio)
- Selpercatinib (Retevmo)
- Selumetinib (Koselugo)
- Serplulimab (Hansizhuang)
- Sintilimab (Tyvyt)
- Sipuleucel-T (Provenge)
- Sirolimus protein-bound particles (Fyarro)
- Sonidegib (Odomzo)
- Sorafenib (Nexavar)
- Sotorasib (Lumakras)
- Stilbamidine
- Streptozocin (Zanosar)
- Strontium-89 (Metastron)
- Sugemalimab (Cejemly)
- Sunitinib (Sutent)
- Suramin (Antrypol)
T
- Tabelecleucel (Ebvallo)
- Tafasitamab (Monjuvi)
- Tagraxofusp (Elzonris)
- Talazoparib (Talzenna)
- Talimogene laherparepvec (Imlygic)
- Taloporfin (Laserphyrin)
- Talquetamab (Talvey) FDA approved 2023-08-09
- Tamibarotene (Amnoid)
- Tamoxifen (Nolvadex)
- Tarlatamab (Imdelltra) FDA approved 2024-05-16
- Tasonermin (Beromun)
- Tazemetostat (Tazverik)
- Tebentafusp (Kimmtrak)
- Teclistamab (Tecvayli)
- Tegafur and uracil (UFT)
- Tegafur, gimeracil, oteracil (Teysuno, S-1)
- Temoporfin (Foscan)
- Temozolomide (Temodar)
- Temsirolimus (Torisel)
- Teniposide (Vumon)
- Tepotinib (Tepmetko)
- Thalidomide (Thalomid)
- Thioguanine (Tabloid)
- Thiotepa (Tepadina)
- Thiotepa (Thioplex)
- Tirabrutinib (Velexbru)
- Tisagenlecleucel (Kymriah)
- Tisotumab vedotin (Tivdak)
- Topotecan (Hycamtin)
- Toremifene (Fareston)
- Toripalimab (Loqtorzi) FDA approved 2023-10-27
- Tositumomab and I-131 (Bexxar)
- Tovorafenib (Ojemda) FDA approved 2024-04-23
- Trabectedin (Yondelis)
- Trametinib (Mekinist)
- Trastuzumab (Herceptin)
- Trastuzumab and hyaluronidase (Herceptin Hylecta)
- Trastuzumab deruxtecan (Enhertu)
- Trastuzumab emtansine (Kadcyla)
- Tremelimumab (Imjudo)
- Treosulfan (Ovastat)
- Trifluridine and tipiracil (Lonsurf)
- Trilostane (Vetoryl)
- Trimetrexate (Neutrexin)
- Triptorelin (Trelstar LA)
- Trofosfamide (Ixoten)
- Tucatinib (Tukysa)
U
- Ublituximab (Briumvi) FDA approved 2023-01-06
V
- Valemetostat (Ezharmia)
- Valrubicin (Valstar)
- Vandetanib (Caprelsa)
- Vemurafenib (Zelboraf)
- Venetoclax (Venclexta)
- Vinblastine (Velban)
- Vincristine (Oncovin)
- Vindesine (Eldisine)
- Vinflunine (Javlor)
- Vinorelbine (Navelbine)
- Vismodegib (Erivedge)
- Vorinostat (Zolinza)
- Voxelotor (Oxbryta)
Z
- Zanubrutinib (Brukinsa)
- Zimberelimab (Yu Duo)
- Ziv-aflibercept (Zaltrap)
- Aflibercept-jbvf (Yesafili) FDA approved 2024-05
- Aflibercept-yszy (Opuviz) FDA approved 2024-05
Discontinued antineoplastics
This section contains drugs that have had at least one formal approval in any domain (FDA, EMA, etc), but are no longer on the market. Note that it is possible that these drugs continue to be available in some limited way, such as through compassionate use programs.
A
D
E
F
L
M
O
P
S
T
U
V
Investigational antineoplastics
This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.
A
- Abexinostat (PCI-24781)
- Actinium Ac 225 lintuzumab (Actimab-A)
- Adavosertib (MK-1775)
- Adebrelimab (SHR-1316)
- Adenovirus-interferon-γ (TG-1042)
- Afamitresgene Autoleucel (ADP-A2M4)
- Afuresertib (GSK-2110183)
- Agatolimod (PF-3512676)
- Alisertib (MLN-8237)
- Amatuximab (MORAb-009)
- Amonafide (Quinamed)
- Apocept (APG-101)
- Astuprotimut-R (GSK-1572932A)
B
- Barasertib (AZD-1152)
- Bavituximab (PGN-401)
- Befotertinib (D-0316)
- Belagenpumatucel-L (Lucanix)
- BE-CAR7
- BHQ-880
- Birtamimab (NEOD-001)
- BL22 immunotoxin (CAT-3888)
- Buparlisib (BKM-120)
C
- CARv3-TEAM-E T-cells
- Catumaxomab (Removab) in US clinical trials
- Cediranib (Recentin)
- Cixutumumab (IMC-A12)
- Coltuximab ravtansine (SAR-3419)
- Crenolanib (CP-868,596)
- Custirsen (OGX-011)
D
- Dalpiciclib (SHR-6390)
- Danicopan (ALXN-2040)
- Datopotamab deruxtecan (DS-1062)
- Denintuzumab mafodotin (SGN-CD19A)
- Dinaciclib (SCH-727965)
- Divarasib (GDC-6036)
- Discodermolide (XAA-296)
- DMUC-5754A
- Dovitinib (TKI-258)
E
- Emepepimut-S (Stimuvax)
- Eluvixtamab (AMG-330)
- Entinostat (SNDX-275)
- Entospletinib (GS-9973)
- Envonalkib (TQ-B3139)
- Epratuzumab (LymphoCide)
- Etirinotecan pegol (NKTR-102)
F
G
- G207
- Galeterone (TOK-001)
- Galunisertib (LY-2157299)
- Ganetespib (STA-9090)
- Ganitumab (AMG-479)
- GD2-CART01
- Gemcitabine elaidate (CP-4126)
- Glembatumumab vedotin (CDX-011)
- Guadecitabine (SGI-110)
H
I
J
L
- Lapuleucel-T (DN24-02)
- Lestaurtinib (CEP-701)
- Linifanib (ABT-869)
- Linsitinib (OSI-906)
- Lorvotuzumab mertansine (BB-10901)
- Lutetium-177-PSMA-617
- LY-3023414
M
- Magrolimab (Hu5F9-G4)
- Mapatumumab (HGS-ETR1)
- Masitinib (AB-1010)
- MCARH-109
- Mezigdomide (BMS-986348)
- Milataxel (TL-139)
- MK-2206
- Mocetinostat (MGCD-0103)
- Motesanib (AMG-706)
N
O
- Oblimersen (Genasense)
- Olaptesed pegol (NOX-A12)
- Onartuzumab (MetMAb)
- Oprozomib (ONX-0912)
- Orteronel (TAK-700)
- Osocimab (BAY-1213790)
- Otlertuzumab (TRU-016)
P
- Patritumab deruxtecan (U3-1402)
- Pentraxin 2 (PRM-151)
- Perifosine (KRX-0401)
- Phosphomannopentaose sulfate (PI-88)
- Pictilisib (GDC-0941)
- Pidilizumab (CT-011)
- Pimitespib (TAS-116)
- Pinatuzumab vedotin (DCDT-2980S)
- Plinabulin (NPI-2358)
- Pracinostat (SB-939)
Q
R
- Rebimastat (BMS-275291)
- Refametinib (BAY-869766)
- Reovirus (Reolysin)
- Retaspimycin (IPI-504)
- Revumenib (SNDX-5613)
- Rezvilutamide (SHR-3680)
- Ricolinostat (ACY-1215)
- Ridaforolimus (AP-23573)
- Rilotumumab (AMG-102)
- Ripertamab (SCT-400)
- Rociletinib (CO-1686)
S
- Sapacitabine (CS-682)
- Sapanisertib (MLN-0128)
- Seliciclib (CYC-202)
- Semuloparin (AVE-5026)
- Spebrutinib (CC-292)
- Surufatinib (HMPL-012)
T
- Tabalumab (LY-2127399)
- Tasadenoturev (DNX-2401)
- Telisotuzumab vedotin (ABBV-399)
- Tertomotide (GV-1001)
- Tesetaxel (DJ-927)
- Tesevatinib (XL-647)
- Tigatuzumab (CS-1008)
- Tipifarnib (Zarnestra)
- Tirapazamine (Tirazone)
- Tislelizumab (Baizean)
- Tivantinib (ARQ-197)
- Tivozanib (AV-951)
- Tosedostat (CHR-2797)
- Trebananib (AMG-386)
- Tusamitamab ravtansine (SAR-408701)
U
V
- Vadastuximab talirine (SGN-CD33A)
- Vadimezan (AS-A404)
- Varlilumab (CDX-1127)
- Veliparib (ABT-888)
- Veltuzumab (hA20)
- Volasertib (BI-6727)
- Vorasidenib (AG-881)
- Vorolanib (CM-082)
- Vosaroxin (SNS-595)
- Voxtalisib (XL-765)
Z
Supportive and other medications
This section contains supportive drugs that are either approved or investigational. Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound.
A
- Abciximab (ReoPro)
- Acetaminophen (Tylenol)
- Acetazolamide (Diamox)
- Acyclovir (Zovirax)
- ADAMTS13, recombinant (Adzynma)
- Alendronate (Fosamax)
- Alizapride (Litican)
- Allopurinol (Zyloprim)
- Alprazolam (Xanax)
- Aminocaproic acid (Amicar)
- Amoxicillin
- Anagrelide (Agrylin)
- Andexanet alfa (Andexxa)
- Anti-inhibitor coagulant complex (FEIBA NF)
- Antithrombin III (human and recombinant)
- Antithymocyte globulin, horse ATG (Atgam)
- Antithymocyte globulin, rabbit ATG (Grafalon)
- Antithymocyte globulin, rabbit ATG (Thymoglobulin)
- Apixaban (Eliquis)
- Aprepitant (Emend)
- Argatroban (Acova)
- Aripiprazole (Abilify)
- Ascorbic acid (Vitamin C)
- Aspirin
- Aspirin and dipyridamole (Aggrenox)
- Atropine (Atropen)
- Atovaquone (Mepron)
- Avatrombopag (Doptelet)
- Azathioprine (Imuran)
B
- Betibeglogene autotemcel (Zynteglo)
- Betrixaban (Bevyxxa)
- Bismuth subsalicylate (Pepto-Bismol)
- Bivalirudin (Angiomax)
C
- Cangrelor (Kengreal)
- Calcium phosphate rinse (Caphosol)
- Caspofungin (Cancidas)
- Cetirizine (Zyrtec)
- Chlorpheniramine (Chlor-Trimeton)
- Cilostazol (Pletal)
- Cimetidine (Tagamet)
- Ciprofloxacin (Cipro)
- Clarithromycin (Biaxin)
- Clemastine (Tavist)
- Clodronate (Bonefos)
- Clopidogrel (Plavix)
- CM-313
- Concizumab (Alhemo)
- Crizanlizumab (Adakveo)
- Cyanocobalamin (Vitamin B12)
- Cyclosporine
- Cytomegalovirus Immune Globulin (Cytogam)
D
- Dabigatran (Pradaxa)
- Dalteparin (Fragmin)
- Danazol (Danocrine)
- Dapsone (Aczone)
- Darbepoetin alfa (Aranesp)
- Deferasirox (Exjade)
- Deferasirox (Jadenu)
- Deferiprone (Ferriprox)
- Deferoxamine (Desferal)
- Defibrotide (Defitelio)
- Denosumab (Xgeva)
- Desmopressin (DDAVP)
- Dexchlorpheniramine (Polaramine)
- Dexrazoxane (Zinecard)
- Diphenhydramine (Benadryl)
- Dipyridamole (Persantine)
- Docusate (Colace)
- Dolasetron (Anzemet)
- Domperidone (Motilium)
- Doxycycline
- Dronabinol (Marinol)
E
- Eculizumab (Soliris)
- Edoxaban (Savaysa)
- Efanesoctocog alfa (Altuviiio)
- Eflapegrastim (Rolvedon)
- Eltrombopag (Promacta)
- Emicizumab (Hemlibra)
- Enoxaparin (Lovenox)
- Epoetin alfa (Procrit)
- Epoetin theta (Biopoin)
- Epoetin zeta (Eprex)
- Eptifibatide (Integrilin)
- Etranacogene dezaparvovec (Hemgenix)
- Exagamglogene autotemcel (Casgevy) FDA approved on 2023-12-08
F
- Factor VIIa, recombinant (NovoSeven RT)
- Factor VIII, human
- Factor VIII, recombinant
- Factor IX, human
- Factor IX, recombinant
- Factor IX, recombinant, Fc fusion protein (Alprolix)
- Factor X, human (Coagadex)
- Factor XIII concentrate, human (Corifact)
- Famciclovir (Famvir)
- Famotidine (Pepcid)
- Ferric carboxymaltose (Injectafer)
- Ferric derisomaltose (Monoferric)
- Ferric gluconate (Ferrlecit)
- Ferrous sulfate (Feosol)
- Ferumoxytol (Feraheme)
- Fibrinogen concentrate, human (RiaSTAP)
- Filgrastim (Neupogen)
- Finasteride (Proscar)
- Fitusiran (ALN-AT3SC)
- Fluconazole (Diflucan)
- Folic acid (Folate)
- Fondaparinux (Arixtra)
- Fosaprepitant (Emend for Injection)
- Fosnetupitant (Arokaris)
- Furosemide (Lasix)
G
H
I
- Ibandronate (Boniva)
- Idarucizumab (Praxbind)
- Indomethacin (Indocin)
- Iptacopan (Fabhalta) FDA approved 2023-12-05
- Iron dextran (INFeD)
- Iron sucrose (Venofer)
- Itraconazole (Sporanox)
L
- Lactulose
- Lamivudine (Epivir)
- Lansoprazole (Prevacid)
- Lenograstim (Granocyte)
- Lepirudin (Refludan) discontinued
- Letermovir (Prevymis)
- Levofloxacin (Levaquin)
- L-glutamine (Endari)
- Lipefilgrastim (Lonquex)
- Loperamide (Imodium)
- Lorazepam (Ativan)
- Lovotibeglogene autotemcel (Lyfgenia) FDA approved on 2023-12-08
- Luspatercept (Reblozyl)
- Lusutrombopag (Mulpleta)
M
- Mannitol
- Meperidine (Demerol)
- Mesna (Mesnex)
- Methyltesterone (Android)
- Metoclopramide (Reglan)
- Mitapivat (Pyrukynd)
- Motixafortide (Aphexda) FDA approved 2023-09
- Mycophenolate mofetil (CellCept)
N
O
- Olanzapine (Zyprexa)
- Omeprazole (Prilosec)
- Omidubicel (Omisirge) FDA approved 2023-04-17
- Ondansetron (Zofran)
- Oprelvekin (Neumega)
P
- Palifermin (Kepivance)
- Palonosetron (Aloxi)
- Pamidronate (Aredia)
- Pantoprazole (Protonix)
- Pegfilgrastim (Neulasta)
- Pegfilgrastim-apgf (Nyvepria)
- Pegfilgrastim-bmez (Ziextenzo)
- Pegfilgrastim-cbqv (Udenyca)
- Pegfilgrastim-fpgk (Stimufend)
- Pegfilgrastim-jmdb (Fulphila)
- Pegfilgrastim-cegf (Cegfila)
- Pegfilgrastim-gras (Grasustek)
- Pegfilgrastim-pbbk (Fylnetra)
- Pegfilgrastim-pelg (Pelgraz)
- Pegfilgrastim-pelm (Pelmeg)
- Pegfilgrastim-stim (Stimufend)
- Penicillin V
- Pentamidine (Nebupent)
- Phenytoin (Dilantin)
- Phytonadione (Vitamin K)
- Plerixafor (Mozobil)
- Prasugrel (Effient)
- Pravastatin (Pravachol)
- Prochlorperazine (Compazine)
- Promethazine (Phenergan)
- Protamine sulfate
- Protein C, human (Ceprotin)
- Prothrombin Complex Concentrate, human
Q
R
- Rabeprazole (Aciphex)
- Raloxifene (Evista)
- Ramosetron (Iribo)
- Ranitidine (Zantac)
- Rasburicase (Elitek)
- Remestemcel-L (Prochymal)
- Rho(D) immune globulin (RhoGAM)
- Rilzabrutinib (PRN-1008)
- Risedronate (Actonel)
- Rivaroxaban (Xarelto)
- Rolapitant (Varubi)
- Romiplostim (Nplate)
- Rusfertide (PTG-300)
S
- Sargramostim (Leukine)
- Scopolamine (Scopoderm)
- Sennosides (Senna)
- Siltuximab (Sylvant)
- Sirolimus (Rapamune)
- Sodium thiosulfate (Pedmark)
- Sutimlimab (Enjaymo)
T
- Tacrolimus (Prograf)
- Tbo-filgrastim (Granix)
- Telotristat (Xermelo)
- Ticagrelor (Brilinta)
- Ticlopidine (Ticlid)
- Tinzaparin (Innohep)
- Tirofiban (Aggrastat)
- Tocilizumab (Actemra)
- Tofacitinib (Xeljanz)
- Tranexamic acid (Cyklokapron)
- Trilaciclib (Cosela)
- Trimethoprim-Sulfamethoxazole (Bactrim DS)
- Tropisetron (Navoban)
U
V
- Valacyclovir (Valtrex)
- Valganciclovir (Valcyte)
- Valoctocogene roxaparvovec (AAV5-hFVIII-SQ)
- Valproate (Depakote)
- Verbrinacogene setparvovec (FLT-180a)
- von Willebrand factor and factor VIII complex, human
- von Willebrand factor, recombinant
- Vonoprazan (Takecab)
- Vorapaxar (Zontivity)
- Voriconazole (Vfend)
W
Z
By Category
Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is an ongoing process so not all of these links are active or current).
Drugs in a REMS program
Cytotoxic Chemotherapy
- Alkylating agents
- Anthracyclines
- Antimetabolites
- DNA synthesis inhibitors
- Microtubule inhibitors
- Nitrogen mustards
- Nitrosureas
- Platinum agents
- Proteasome inhibitors
- Taxanes
- Topoisomerase inhibitors
- Vinca alkaloids
Kinase inhibitors
- AKT1 inhibitors
- ALK inhibitors
- Aurora kinase inhibitors
- AXL inhibitors
- Bcr-Abl inhibitors
- BRAF inhibitors
- BTK inhibitors
- CDK inhibitors
- EGFR inhibitors
- ERBB2 inhibitors
- ERBB4 inhibitors
- FGFR inhibitors
- FLT3 inhibitors
- IGFR inhibitors
- JAK inhibitors
- KIT inhibitors
- MEK inhibitors
- MET inhibitors
- mTOR inhibitors
- PDGFR inhibitors
- PI3K inhibitors
- PLK1 inhibitors
- RET inhibitors
- ROS1 inhibitors
- SRC inhibitors
- SYK inhibitors
- TEK inhibitors
- TRK inhibitors
- VEGF inhibitors
Endocrine therapy
- Antiandrogens
- Steroid synthesis inhibitors
- Androgen receptor inhibitors
- 5 alpha-reductase inhibitors
- GnRH agonists
- GnRH antagonists
- Aromatase inhibitors
- Selective estrogen receptor modulators
- Steroids
- Somatostatin analogs
Investigational and Discontinued
Biologics
- Antibody medications
- Antibody-drug conjugates
- Anti-HER2 medications
- IL-6 inhibitors
- Enzymes
- Immunotherapy
- Immunomodulatory drugs (IMiDs)
Supportive Medications
- Antibacterials
- Antidiarrheals
- Antifungals
- Antihistamines
- Antivirals
- Bisphosphonates
- Chemotherapy protective agents
- Emesis prevention
- PCP prophylaxis
- RANK ligand inhibitors
- Steroids
Radioactive agents
Benign Hematology Medications
Hematopoietic Growth Factors
Miscellaneous
- Drugs in a REMS program
- HDAC inhibitors
- Hypomethylating agents
- Retinoids
- WHO Essential Cancer Medicines
Medications by Condition
- Acute lymphocytic leukemia medications
- Acute myeloid leukemia medications
- Acute promyelocytic leukemia medications
- Anal cancer medications
- Anaplastic large cell lymphoma medications
- Bladder cancer medications
- Bone cancer medications
- Breast cancer medications
- Burkitt lymphoma medications
- Cancer of unknown primary medications
- Castleman disease medications
- Central nervous system (CNS) cancer medications
- Central nervous system (CNS) lymphoma medications
- Cervical cancer medications
- Chronic lymphocytic leukemia (CLL/SLL) medications
- Chronic myeloid leukemia (CML) medications
- Chronic myelomonocytic leukemia (CMML) medications
- Colon cancer medications
- Colorectal cancer (CRC) medications
- Cutaneous BCC medications
- Cutaneous SCC medications
- Cutaneous T-cell lymphoma medications
- Diffuse large B-cell lymphoma medications
- Endometrial cancer medications
- Esophageal cancer medications
- Essential thrombocythemia medications
- Extranodal NK/T-cell lymphoma, nasal type lymphoma medications
- Follicular lymphoma medications
- Gastric cancer medications
- Hairy cell leukemia medications
- Head and neck cancer medications
- Hepatobiliary cancer medications
- HIV-associated lymphoma medications
- Hodgkin lymphoma medications
- Hodgkin lymphoma, nodular lymphocyte-predominant medications
- Immune thrombocytopenic purpura (ITP) medications
- Light-chain (AL) amyloidosis medications
- Mantle cell lymphoma medications
- Marginal zone lymphoma medications
- Mediastinal gray-zone lymphoma medications
- Melanoma medications
- Mesothelioma medications
- Multiple myeloma medications
- Myelodysplastic syndrome medications
- Myelofibrosis medications
- NK/T-cell lymphoma medications
- Non-small cell lung cancer medications
- Neuroendocrine tumor medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Paroxysmal nocturnal hemoglobinuria (PNH) medications
- Penile cancer medications
- Peripheral T-cell lymphoma medications
- Plasma cell leukemia medications
- Polycythemia vera medications
- Primary mediastinal B-cell lymphoma medications
- Prostate cancer medications
- Rectal cancer medications
- Renal cell carcinoma medications
- Sarcoma medications
- Sickle cell anemia medications
- Small cell lung cancer medications
- T-cell lymphoma medications
- Testicular cancer medications
- Thymoma medications
- Thyroid cancer medications
- Transformed lymphoma medications
- Transplant medications
- Waldenström macroglobulinemia medications
Medications by Route of Administration
- Intraarterial (IA) medications
- Intracavitary medications
- Intramuscular (IM) medications
- Intrathecal (IT) medications
- Intravenous (IV) medications
- Intravesicular medications
- Oral (PO) medications
- Subcutaneous (SC) medications
Medications by FDA Year of Approval
- FDA approved in 1939
- FDA approved in 1941
- FDA approved in 1946
- FDA approved in 1949
- FDA approved in 1951
- FDA approved in 1952
- FDA approved in 1953
- FDA approved in 1954
- FDA approved in 1955
- FDA approved in 1956
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- FDA approved in 2024
Interesting and Helpful Links
- Antidepressants and other psychiatric medications in cancer care
- Antiemetic support
- Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology Clinical Practice Guideline (2013)
- 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society (ASCO/ONS) Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology
- Chemotherapy Administration Sequence[3] - with chemotherapy sequencing chart
- The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy. PubMed
- CredibleMeds.org - lists of QT-prolonging drugs; requires free registration to see full list
- FDA drug shortages list
- ASHP drug shortages list - also includes information about discontinued drugs
- DailyMed - a comprehensive NLM portal to all FDA-approved drugs
- Drugs@FDA - the main portal into the FDA drug database
- The NCI Drug Dictionary - an extensive resource with most antineoplastics (approved and in clinical trials) listed
- In the Pipeline - a blog from a veteran of the pharmaceutical industry, Derek Lowe. General but much is cancer-relevant. The old home of this blog is no longer active.
- Steroid conversions
- Vesicant & irritant chemotherapy
- Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers
- CPIC Guidelines The Clinical Pharmacogenetics Implementation Consortium provides guidelines for a small set of drugs with pharmacogenetically-guided dosing implications, some of which are oncologics
References
- ↑ Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. link to original article PubMed
- ↑ Smith TJ, Bohlke K, Lyman GH, Carson KR, Crawford J, Cross SJ, Goldberg JM, Khatcheressian JL, Leighl NB, Perkins CL, Somlo G, Wade JL, Wozniak AJ, Armitage JO. Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015 Oct 1;33(28):3199-212. Epub 2015 Jul 13. link to original article PubMed
- ↑ Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. link to original article