Anastrozole (Arimidex)

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General information

Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.[1][2][3]
Route: PO
Extravasation: n/a

For conciseness and simplicity, currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is used

Patient drug information

History of changes in FDA indication

  • 12/27/1995: Initial FDA approval

Also known as

  • Brand names: Altraz, Anabrez, Anastraze, Anastrazol Rontag, Anastrol, Arimidex, Asiolex, Karomex, Leprofen, RUI SI YI, RUI Ting, Trozolet, Trozolite.


  1. 1.0 1.1 1.2 Anastrozole (Arimidex) package insert
  2. Anastrozole (Arimidex) package insert (locally hosted backup)
  3. Arimidex manufacturer's website
  4. Anastrozole (Arimidex) patient drug information (Chemocare)
  5. Anastrozole (Arimidex) patient drug information (UpToDate)