Raloxifene (Evista)

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General information

Class/mechanism: SERM (selective estrogen receptor modulator), with estrogen agonist/antagonist properties depending on tissue type. Raloxifene has estrogen antagonist properties in uterine and breast tissues. However, it has estrogen agonist properties in bone, helping to decrease bone resorption.[1][2]
Route: PO
Extravasation: n/a

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, or the prescribing information.[1]

Patient drug information

History of changes in EMA indication

  • 1998-08-05: EURD

Also known as

  • Brand names: Evista, Ralista, Razylan

References