Factor VIII, recombinant

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General information

Class/mechanism: Recombinant Factor VIII; replaces the missing clotting factor VIII that is required for hemostasis in patients with hemophilia A.
Please choose from the products below to find specific drug/manufacturer information:

Route: IV
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.

Diseases for which it is used

  • Hemophilia A

Patient drug information

Also known as

  • Generic name: recombinant coagulation factor 8
  • Brand names: Advate rAHF-PFM, Helixate, Helixate FS, Kogenate, Kogenate FS, Recombinate, Refacto, Xyntha

References

  1. Advate manufacturer's website
  2. 2.0 2.1 Factor VIII, recombinant (Advate) package insert
  3. Factor VIII, recombinant (Advate) package insert (locally hosted backup)
  4. Helixate FS manufacturer's website
  5. 5.0 5.1 Factor VIII, recombinant (Helixate FS) package insert
  6. Factor VIII, recombinant (Helixate FS) package insert (locally hosted backup)
  7. Kogenate FS manufacturer's website
  8. 8.0 8.1 Factor VIII, recombinant (Kogenate FS) package insert
  9. Factor VIII, recombinant (Kogenate FS) package insert (locally hosted backup)
  10. Recombinate manufacturer's website
  11. 11.0 11.1 Factor VIII, recombinant (Recombinate) package insert
  12. Factor VIII, recombinant (Recombinate) package insert (locally hosted backup)
  13. 13.0 13.1 Factor VIII, recombinant (ReFacto) package insert
  14. Factor VIII, recombinant (ReFacto) package insert (locally hosted backup)
  15. Xyntha manufacturer's website
  16. 16.0 16.1 Factor VIII, recombinant (Xyntha) package insert
  17. Factor VIII, recombinant (Xyntha) package insert (locally hosted backup)
  18. Factor VIII, recombinant (antihemophilic factor 8) patient drug information (UpToDate)