All-trans retinoic acid (ATRA)

From - A Hematology Oncology Wiki
Jump to: navigation, search

General information

Class/mechanism: Retinoid, induces maturation/differentiation of acute promyelocytic leukemia (APL) cells. Exact mechanism unknown.[1][2]
Route: PO
Extravasation: n/a

For conciseness and simplicity, currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is used

Patient drug information

History of changes in FDA indication

  • 11/22/1995: Initial FDA approval

Also known as

Antismallpox A-acido A-acido Emoliente A-acido Vital A-RET A-tinic A-vitaminsyre A.A
Aberel Aberela AC.retinoic GI Acfen-A Acid A VIT Acido Retinoico Acido Vital Acnavit
Acned Acnelyse Acretin Acta Acudyne Adina AI LI KE Airful
Airol Ajina Aldoquin Anti-Acne all-trans retinoic acid Alquin-Gel Alten Altinac Arretin
ATRA Atrederm Aviderm Avita Avitcid Betarretin Cordes VAS Cosmotrin
Crometin-A Date Film Dermairol Derma Lightening Dermodan Dermojuventus Derugin DI WEI
Effederm Elra EPI-Aberel Eudyna Extraderm Facely Facenol Funoin
Hidrosam T Jeraklin Kefrane Kerlocal Ketrel Locacid Masc Retynowa Melavita
Microvita Neotretin Nilac Niterey Nuface Olcenon Olcenon Kayaku Quali-A
Recknoin Rejuva-A Renova Retacnyl Retavit Reticne Reticrem Retiderm
Retigel Retin-A Micro Retin A Retinei Retino Retino-A Retino Forte Retinoic Acid
Retinomycin Retinova Retirides Retisol Retisol-A Retitop Retop-A Retrieve
Smooderm Sorfic Stieva A Tracne Tracnesan Trena Trentin Tretin
Tretinax Tretinex Tretinoderm AC Tretinoin Tretinoina Tretinoine Kefrane Tretinoin Tocoferil Tretinoinum
Tretinon Trinon Tronin Vesaoid VIT A Acid Vitanol Vitanol A Vitinoin


  1. 1.0 1.1 Tretinoin (Vesanoid) package insert
  2. Tretinoin (Vesanoid) package insert (locally hosted backup)
  3. Tretinoin (Vesanoid) patient drug information (Chemocare)
  4. Tretinoin (Vesanoid) patient drug information (UpToDate)