Efanesoctocog alfa (Altuviiio)

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Mechanism of action

From Wikipedia: Efanesoctocog alfa is a recombinant DNA-derived, Factor VIII concentrate.

Diseases for which it is used

History of changes in FDA indication

  • 2023-02-22: Initial approval for use in adults and children with Hemophilia A (congenital Factor VIII deficiency) for: (1) Routine prophylaxis to reduce the frequency of bleeding episodes; (2) On-demand treatment and control of bleeding episodes; and (3) Perioperative management of bleeding. (Based on XTEND-1)
  • 2024-05-10: Approval updated to include additional evidence. (Based on XTEND-Kids)

Also known as

  • Code name: BIVV-001
  • Brand name: Altuviiio