Class/mechanism: A second-generation cisplatin analogue with antineoplastic activity. Containing a novel ring structure in which glycolate is bound to the platinum by a bidentate ligand, nedaplatin forms reactive platinum complexes that bind to nucelophillic groups in DNA, resulting in intrastrand and interstrand DNA cross-links, apoptosis and cell death. 
Extravasation: no information
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Diseases for which it is used
Also known as
- Code name: 254-S
- Generic name: nedaplat
- Brand name: Aqupla, Jiebaishu