Caplacizumab (Cablivi)

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Mechanism of action

A single domain antibody directed against the A1 domain of von Willebrand factor (vWF).

Diseases for which it is used

History of changes in FDA indication

History of changes in EMA indication

  • 2018-08-30: Initial authorization

History of changes in PMDA indication

Patient Drug Information

Also known as

  • Code name: ALX-0081
  • Generic name: caplacizumab-yhdp
  • Brand name: Cablivi