Vinblastine (Velban)

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General information

Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.[1][2]
Route: IV
Extravasation: vesicant

For conciseness and simplicity, currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Patient drug information

Diseases for which it is used

Diseases for which it was used

History of changes in FDA indication

Also known as

  • Generic names: chlorhexamide, vinblastine sulfate, vinblastine sulphate, vincaleukoblastine, VLB
  • Brand names:
Alkaban-AQ Blastovin Cellblastin Cytoblastine Erbablas
Exal Faulblastina Lemblastine Periblastine Rabinefil
Velban Velbastine Velbe Vinblasin Vinblastin