Class/mechanism: Recombinant human granulocyte colony-stimulating factor (G-CSF), biosimilar of pegfilgrastim. Binds to cell surface receptors on hematopoietic cells and stimulates proliferation‚ differentiation, and some end-cell functional activation.
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History of changes in FDA indication
- 6/4/2018: FDA approved to decrease the chance of infection as suggested by febrile neutropenia in patients with non-myeloid cancer who are receiving myelosuppressive chemotherapy that has a clinically significant incidence of febrile neutropenia.
Also known as
- Generic names: pegylated GCSF, pegylated G-CSF, pegylated granulocyte colony stimulating factor
- Brand names: Fulphila