Class/mechanism: Gonadotropin-releasing hormone (GnRH) receptor antagonist. Reversibly binds to pituitary GnRH receptors, reducing the release of luteinizing hormone (LH) and follicle stimulation hormone (FSH), resulting in rapid androgen deprivation/decreased testosterone levels. There is no initial testosterone surge/flare with relugolix, in contrast to GnRH agonists.
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Diseases for which it is used
Patient drug information
History of changes in FDA indication
- 12/18/2020: Approved for adult patients with advanced prostate cancer. (Based on HERO)
Also known as
- Code name: TAK-385
- Brand names: Orgovyx, Relumina