Rho(D) immune globulin (RhoGAM)
Class/mechanism: Not entirely known. Rho(D) immune globulin forms anti-D-coated red blood cell complexes which are thought to bind to macrophage receptors in the spleen. This is then hypothesized to block the spleen's clearance of antibody-coated cells, which include platelets. Thus, the destruction of platelets in ITP is limited.
Extravasation: no information
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