Class/mechanism: C-Met inhibitor. Inappropriate or constitutive activation of the receptor tyrosine kinase c-Met and its signalling pathway is implicated in many cancers, playing a role in abnormal proliferation, survival, invasion, metastasis, and angiogenesis.
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Diseases for which it is used
Patient drug information
History of changes in FDA indication
- 2/3/2021: Granted accelerated approval for adult patients with metastatic non-small cell lung cancer (NSCLC) harboring mesenchymal-epithelial transition (MET) exon 14 skipping alterations. (Based on VISIONNSCLC)
Also known as
- Code names: EMD-1214063, MSC-2156119, MSC-2156119J
- Brand name: Tepmetko