Nimustine (ACNU)

General information

Class/mechanism: Nitrosourea, alkylates DNA and RNA and may inhibit certain key enzymatic reactions by carbamoylation of amino acids in proteins.
Route: IV
Extravasation: n/a

Diseases for which it was used

• Anaplastic glioma
• Glioblastoma

Also known as

• Generic names: ACNU, pimustine
• Brand name: Nidran