Desmopressin (DDAVP)

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General information

Class/mechanism: Synthetic analog of vasopressin (ADH/antidiuretic hormone). In addition to its antidiuretic effects, also stimulates release of factor VIII and von Willebrand factor.[1][2][3][4][5][6]
Route: SC, IV, PO, intranasal
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1][3][5]

Patient drug information

Authorized distributors

The most current list of distributors can found at CSL Behring's website.[8]

  • ABO Pharmaceuticals
  • AmeriSource Bergen
  • Bellco Drug Company
  • Burlington Drug Company
  • Capital Wholesale
  • Cardinal Health
  • D & K Healthcare
  • Dakota Drug
  • F. Dohmen Wholesale
  • FFF Enterprises
  • Frank W. Kerr Wholesale
  • James W. Daly Wholesale
  • Kinray
  • Miami-Luken Inc.
  • McKesson Plasma and Biologics
  • McQueary Brothers
  • N.C Mutual Wholesale
  • Rochester Drug
  • Smith Wholesale
  • Whitmire Drug
  • Value Drug

Also known as

  • Brand names: DDAVP, DesmoMelt, Desmotabs, Desonap, Minirin, Stimate

References

  1. 1.0 1.1 Desmopressin (DDAVP tablet) package insert
  2. Desmopressin (DDAVP tablet) package insert (locally hosted backup)
  3. 3.0 3.1 3.2 Desmopressin (DDAVP nasal) package insert
  4. Desmopressin (DDAVP nasal) package insert (locally hosted backup)
  5. 5.0 5.1 Desmopressin (DDAVP injection) package insert
  6. Desmopressin (DDAVP injection) package insert (locally hosted backup)
  7. Desmopressin (DDAVP) patient drug information (UpToDate)
  8. CSL Behring's list of authorized Stimate distributors