Cyanocobalamin (Vitamin B12)

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Also known as CaloMist, Ener-B, Nascobal, Twelve Resin-K.

General information

Class/mechanism: Vitamin B12, which is instrumental to normal cell growth, reproduction, hematopoiesis, and synthesis of nucleoprotein and myelin.[1][2][3][4][5]
Route: IM, PO, SC, intranasal
Extravasation: n/a

For conciseness and simplicity, currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1][4]

Patient drug information


  1. 1.0 1.1 Cyanocobalamin (Vitamin B12) package insert
  2. Cyanocobalamin (Vitamin B12) package insert (locally hosted backup)
  3. Nascobal manufacturer's website
  4. 4.0 4.1 4.2 Cyanocobalamin nasal (Nascobal) package insert
  5. Cyanocobalamin nasal (Nascobal) package insert (locally hosted backup)
  6. Cyanocobalamin (Vitamin B12) patient drug information (UpToDate)