Factor VIII, human

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General information

Class/mechanism: Factor VIII; replaces the missing clotting factor VIII that is required for hemostasis in patients with hemophilia A.
Please choose from the products below to find specific drug/manufacturer information:

Route: IV
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.

Diseases for which it is used

  • Hemophilia A

Also known as

  • Generic name: coagulation factor 8
  • Brand names: Hemofil-M, Koate-DVI, Koate-HP, Monarc-M, Monoclate-P

References

  1. Hemofil-M manufacturer's website
  2. Factor VIII, human (Hemofil-M) package insert
  3. Factor VIII, human (Hemofil-M) package insert (locally hosted backup)
  4. Koate-DVI manufacturer's website
  5. Factor VIII, human (Koate-DVI) package insert
  6. Factor VIII, human (Koate-DVI) package insert (locally hosted backup)
  7. Factor VIII, human (Monarc-M) package insert
  8. Factor VIII, human (Monarc-M) package insert (locally hosted backup)
  9. Monoclate-P manufacturer's website
  10. Factor VIII, human (Monoclate-P) package insert
  11. Factor VIII, human (Monoclate-P) package insert (locally hosted backup)