Interferon alfa-2b (Intron-A)

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General information

Class/mechanism: Immune system activator; binds to cell surface receptors that modulate many downstream intracellular signal transduction pathways. Mechanism not fully understood.[1][2][3]
Route: SC, IM, IV, intralesional
Extravasation: no information

For conciseness and simplicity, currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is used

Diseases for which it was used

Patient drug information

History of changes in FDA indication

  • 6/4/1986: Initial FDA approval

Also known as

Caution, may also contain names for interferon beta, interferon gamma, or interferon alfa-2a.

Advaferon Alfaferone Berofor Biogamma Canferon A
Cytoferon Egiferon Feron Fiblaferon Frone
Finnferon-Alpha Heberon Alfa R Humoferon IFN Alpha Imufor
Imukin INF Inferax Infergen Inmutag
Interfero Interferon Alfanative Interferon Human Interferon Leucocyticum Interferon Lymphoblastoid
Interferonum Leucocyticum Laroferon Multiferon Namalvin OIF
Polyferon Realdiron Roceron-A Sumiferon Wellferon


  1. 1.0 1.1 Interferon alfa-2b (Intron-A) package insert
  2. Interferon alfa-2b (Intron-A) package insert (locally hosted backup)
  3. Intron-A manufacturer's website
  4. Interferon alfa-2b (Intron-A) patient drug information (Chemocare)
  5. Interferon alfa-2b (Intron-A) patient drug information (UpToDate)