Belumosudil (Rezurock)

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Mechanism of action

ROCK2 (Rho-associated coiled-coil kinase 2) inhibitor

Diseases for which it is used

History of changes in FDA indication

  • 2021-07-16: Approved for adult and pediatric patients 12 years and older with chronic graft-versus-host disease (chronic GVHD) after failure of at least two prior lines of systemic therapy. (Based on ROCKstar)

Also known as

  • Code names: KD-025, SLx-2119
  • Brand name: Rezurock