Difference between revisions of "Drug index"

From HemOnc.org - A Hematology Oncology Wiki
Jump to navigation Jump to search
m (iptacopan added to drug index)
m (Text replacement - "http://www.cancer.gov" to "https://www.cancer.gov")
 
(328 intermediate revisions by 3 users not shown)
Line 1: Line 1:
 +
<span id="BackToTop"></span>
 +
<div class="noprint" style="background-color:LightGray; position:fixed; bottom:2%; right:0.25%; padding-left:5px; padding-right:5px; margin: 15px; opacity:0.8; border-style: solid; border-color:DarkGray; border-width: 1px">
 +
[[#top|Back to Top]]
 +
</div>
 +
=Guidelines=
 +
'''Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any guideline published 5+ years ago to be for historical purposes, only.'''
  
−
=Guidelines=
 
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
'''Other [[#Interesting_and_Helpful_Links|interesting and helpful links]] can be found by clicking the link.'''
 
'''Other [[#Interesting_and_Helpful_Links|interesting and helpful links]] can be found by clicking the link.'''
 
==Chemotherapy safety standards==
 
==Chemotherapy safety standards==
  
−
*'''2020:''' Dillmon et al. [https://doi.org/10.1200/JCO.19.02297 Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards] [https://pubmed.ncbi.nlm.nih.gov/31815576 PubMed]
+
*'''2020:''' Dillmon et al. [https://doi.org/10.1200/JCO.19.02297 Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards] [https://pubmed.ncbi.nlm.nih.gov/31815576/ PubMed]
−
*'''2019:''' Celano et al. [https://doi.org/10.1200/JCO.18.01616 Safe handling of hazardous drugs: ASCO standards] [https://pubmed.ncbi.nlm.nih.gov/30620670 PubMed]
+
*'''2019:''' Celano et al. [https://doi.org/10.1200/JCO.18.01616 Safe handling of hazardous drugs: ASCO standards] [https://pubmed.ncbi.nlm.nih.gov/30620670/ PubMed]
 
*'''2016:''' Neuss et al. [https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards, including standards for pediatric oncology]
 
*'''2016:''' Neuss et al. [https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards, including standards for pediatric oncology]
−
*'''2010:''' Carrington et al. [https://onlinelibrary.wiley.com/doi/10.1111/j.1743-7563.2010.01321.x/full The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy] [https://pubmed.ncbi.nlm.nih.gov/20887505 PubMed]
+
*'''2010:''' Carrington et al. [https://doi.org/10.1111/j.1743-7563.2010.01321.x The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy] [https://pubmed.ncbi.nlm.nih.gov/20887505/ PubMed]
  
 
==Dose adjustments==
 
==Dose adjustments==
 +
*'''2021:''' Griggs et al. [https://doi.org/10.1200/jco.21.00471 Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update]
  
−
*'''2012:''' [https://doi.org/10.1200/jco.2011.39.9436 Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline]<ref>Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. [https://doi.org/10.1200/jco.2011.39.9436 link to original article] [https://pubmed.ncbi.nlm.nih.gov/22473167 PubMed]</ref>
+
*'''2012:''' Griggs et al. [https://doi.org/10.1200/jco.2011.39.9436 Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline]<ref>Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. [https://doi.org/10.1200/jco.2011.39.9436 link to original article] [https://pubmed.ncbi.nlm.nih.gov/22473167/ PubMed]</ref>
  
 
==Antimicrobials==
 
==Antimicrobials==
Line 25: Line 27:
 
*'''2015:''' [https://doi.org/10.1200/jco.2015.62.3488 Update of ASCO Clinical Practice Guideline recommendations for the use of WBC growth factors]<ref>Smith TJ, Bohlke K, Lyman GH, Carson KR, Crawford J, Cross SJ, Goldberg JM, Khatcheressian JL, Leighl NB, Perkins CL, Somlo G, Wade JL, Wozniak AJ, Armitage JO. Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015 Oct 1;33(28):3199-212. Epub 2015 Jul 13. [https://doi.org/10.1200/jco.2015.62.3488 link to original article] [https://pubmed.ncbi.nlm.nih.gov/26169616/ PubMed]</ref>
 
*'''2015:''' [https://doi.org/10.1200/jco.2015.62.3488 Update of ASCO Clinical Practice Guideline recommendations for the use of WBC growth factors]<ref>Smith TJ, Bohlke K, Lyman GH, Carson KR, Crawford J, Cross SJ, Goldberg JM, Khatcheressian JL, Leighl NB, Perkins CL, Somlo G, Wade JL, Wozniak AJ, Armitage JO. Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015 Oct 1;33(28):3199-212. Epub 2015 Jul 13. [https://doi.org/10.1200/jco.2015.62.3488 link to original article] [https://pubmed.ncbi.nlm.nih.gov/26169616/ PubMed]</ref>
  
−
=Antineoplastics=
+
=Approved antineoplastics=
−
 
+
''This section contains anticancer drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound. For drugs first approved within the current or prior calendar years, the date of initial approval is also provided here.''
 
==A==
 
==A==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Abarelix (Plenaxis)]]
 
*[[Abarelix (Plenaxis)]]
 
*[[Abemaciclib (Verzenio)]]
 
*[[Abemaciclib (Verzenio)]]
−
*[[Abexinostat (PCI-24781)]] '''in clinical trials'''
 
 
*[[Abiraterone (Zytiga)]]
 
*[[Abiraterone (Zytiga)]]
 
*[[Acalabrutinib (Calquence)]]
 
*[[Acalabrutinib (Calquence)]]
 
*[[Aclarubicin (Aclacinomycin)]]
 
*[[Aclarubicin (Aclacinomycin)]]
−
*[[Actinium Ac 225 lintuzumab (Actimab-A)]] '''in clinical trials'''
+
*[[Adagrasib (Krazati)]]
−
*[[Adavosertib (MK-1775)]] '''in clinical trials'''
 
−
*[[Adenovirus-interferon-γ (TG1042)]] '''in clinical trials'''
 
−
*[[Ado-trastuzumab emtansine (Kadcyla)]]
 
 
*[[Afatinib (Gilotrif)]]
 
*[[Afatinib (Gilotrif)]]
−
*[[Afuresertib (GSK2110183)]] '''in clinical trials'''
 
 
*[[Aldesleukin (Proleukin)]]
 
*[[Aldesleukin (Proleukin)]]
 
*[[Alectinib (Alecensa)]]
 
*[[Alectinib (Alecensa)]]
 
*[[Alemtuzumab (Campath)]]
 
*[[Alemtuzumab (Campath)]]
−
*[[Alisertib (MLN8237)]] '''in clinical trials'''
 
 
*[[Alitretinoin (Panretin)]]
 
*[[Alitretinoin (Panretin)]]
 
*[[All-trans retinoic acid (ATRA)]]
 
*[[All-trans retinoic acid (ATRA)]]
Line 54: Line 46:
 
*[[Altretamine (Hexalen)]]
 
*[[Altretamine (Hexalen)]]
 
*[[Alvocidib (Flavopiridol)]]
 
*[[Alvocidib (Flavopiridol)]]
−
*[[Amatuximab (MORAb-009)]] '''in clinical trials'''
 
−
*[[AMG 330]] '''in clinical trials'''
 
 
*[[Amifostine (Ethyol)]]
 
*[[Amifostine (Ethyol)]]
 
*[[Aminoglutethimide (Cytadren)]]
 
*[[Aminoglutethimide (Cytadren)]]
−
*[[Aminopterin]] '''discontinued'''
+
*[[Amivantamab (Rybrevant)]]
−
*[[Amonafide (Quinamed)]] '''in clinical trials'''
 
 
*[[Amrubicin (Calsed)]]
 
*[[Amrubicin (Calsed)]]
 
*[[Amsacrine (Amsidine)]]
 
*[[Amsacrine (Amsidine)]]
 
*[[Anastrozole (Arimidex)]]
 
*[[Anastrozole (Arimidex)]]
 
*[[Ancestim (Stemgen)]]
 
*[[Ancestim (Stemgen)]]
 +
*[[Anlotinib (Fukewei)]]
 
*[[Apalutamide (Erleada)]]
 
*[[Apalutamide (Erleada)]]
 
*[[Apatinib (Aitan)]]
 
*[[Apatinib (Aitan)]]
−
*[[Apocept (APG101)]] '''in clinical trials'''
 
 
*[[Arsenic trioxide (Trisenox)]]
 
*[[Arsenic trioxide (Trisenox)]]
−
*[[Asciminib (ABL001)]] '''in clinical trials'''
+
*[[Asciminib (Scemblix)]]
−
*[[Asparaginase (Elspar)]] '''discontinued'''
 
 
*[[Asparaginase Erwinia chrysanthemi (Erwinaze)]]
 
*[[Asparaginase Erwinia chrysanthemi (Erwinaze)]]
−
*[[Astuprotimut-R (GSK1572932A)]] '''in clinical trials'''
+
**[[Asparaginase erwinia chrysanthemi-rywn (Rylaze)]]
 
*[[Atezolizumab (Tecentriq)]]
 
*[[Atezolizumab (Tecentriq)]]
−
*[[Avapritinib (Ayvakit)]] '''FDA approved 1/9/2020'''
+
*[[Aumolertinib (Amelie)]]
 +
*[[Avapritinib (Ayvakit)]]
 
*[[Avelumab (Bavencio)]]
 
*[[Avelumab (Bavencio)]]
 
*[[Axicabtagene ciloleucel (Yescarta)]]
 
*[[Axicabtagene ciloleucel (Yescarta)]]
 
*[[Axitinib (Inlyta)]]
 
*[[Axitinib (Inlyta)]]
−
*[[Azacitidine (Onureg)]] '''FDA approved 9/1/2020'''
+
*[[Azacitidine (Onureg)]]
 
*[[Azacitidine (Vidaza)]]
 
*[[Azacitidine (Vidaza)]]
  
 
==B==
 
==B==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
−
*[[Bacillus Calmette-Guérin (BCG)]]
+
 
−
*[[Barasertib (AZD1152)]] '''in clinical trials'''
+
*[[BCG vaccine]]
−
*[[Bavituximab (PGN401)]] '''in clinical trials'''
+
*[[Belantamab mafodotin (Blenrep)]]
−
*[[Belagenpumatucel-L (Lucanix)]] '''in clinical trials'''
 
−
*[[Belantamab mafodotin (Blenrep)]] '''FDA approved 8/6/2020'''
 
 
*[[Belinostat (Beleodaq)]]
 
*[[Belinostat (Beleodaq)]]
 
*[[Belotecan (Camptobell)]]
 
*[[Belotecan (Camptobell)]]
 +
*[[Belumosudil (Rezurock)]]
 +
*[[Belzutifan (Welireg)]]
 
*[[Bendamustine]]
 
*[[Bendamustine]]
 
*[[Benralizumab (Fasenra)]]
 
*[[Benralizumab (Fasenra)]]
 
*[[Bevacizumab (Avastin)]]
 
*[[Bevacizumab (Avastin)]]
 +
**[[Bevacizumab-adcd (Vegzelga)]]
 +
**[[Bevacizumab-aveg (Avegra)]]
 
**[[Bevacizumab-awwb (Mvasi)]]
 
**[[Bevacizumab-awwb (Mvasi)]]
 +
**[[Bevacizumab-aybi (Aybintio)]]
 
**[[Bevacizumab-bvzr (Zirabev)]]
 
**[[Bevacizumab-bvzr (Zirabev)]]
 +
**[[Bevacizumab-equi (Equidacent)]]
 +
**[[Bevacizumab-maly (Alymsys)]]
 +
**[[Bevacizumab-onbe (Onbevzi)]]
 +
**[[Bevacizumab-tnjn (Avzivi)]] '''FDA approved 2023-12'''
 
*[[Bexarotene (Targretin)]]
 
*[[Bexarotene (Targretin)]]
 
*[[Bicalutamide (Casodex)]]
 
*[[Bicalutamide (Casodex)]]
−
*[[Binimetinib (MEK162)]] '''in clinical trials'''
+
*[[Binimetinib (Mektovi)]]
−
*[[BHQ880]] '''in clinical trials'''
 
−
*[[BL22 immunotoxin (CAT-3888)]] '''in clinical trials'''
 
 
*[[Bleomycin (Blenoxane)]]
 
*[[Bleomycin (Blenoxane)]]
 
*[[Blinatumomab (Blincyto)]]
 
*[[Blinatumomab (Blincyto)]]
 +
*[[Borofalan-10B (Steboronine)]]
 
*[[Bortezomib (Velcade)]]
 
*[[Bortezomib (Velcade)]]
 
*[[Bosutinib (Bosulif)]]
 
*[[Bosutinib (Bosulif)]]
 
*[[Brentuximab vedotin (Adcetris)]]
 
*[[Brentuximab vedotin (Adcetris)]]
−
*[[Brexucabtagene autoleucel (Tecartus)]] '''FDA approved 7/24/2020'''
+
*[[Brexucabtagene autoleucel (Tecartus)]]
 
*[[Brigatinib (Alunbrig)]]
 
*[[Brigatinib (Alunbrig)]]
−
*[[Buparlisib (BKM120)]] '''in clinical trials'''
 
 
*[[Buserelin (Suprefact)]]
 
*[[Buserelin (Suprefact)]]
 
*[[Busulfan (Myleran)]]
 
*[[Busulfan (Myleran)]]
  
 
==C==
 
==C==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Cabazitaxel (Jevtana)]]
 
*[[Cabazitaxel (Jevtana)]]
Line 124: Line 111:
 
*[[Cabozantinib (Cometriq)]]
 
*[[Cabozantinib (Cometriq)]]
 
*[[Calaspargase (Asparlas)]]
 
*[[Calaspargase (Asparlas)]]
 +
*[[Camrelizumab (AiRuiKa)]]
 
*[[Capecitabine (Xeloda)]]
 
*[[Capecitabine (Xeloda)]]
−
*[[Capivasertib (AZD5363)]] '''in clinical trials'''
+
*[[Capivasertib (Truqap)]] '''FDA approved 2023-11-16'''
 
*[[Caplacizumab (Cablivi)]]
 
*[[Caplacizumab (Cablivi)]]
−
*[[Capmatinib (Tabrecta)]] '''FDA approved 5/6/2020'''
+
*[[Capmatinib (Tabrecta)]]
 
*[[Carboplatin (Paraplatin)]]
 
*[[Carboplatin (Paraplatin)]]
 
*[[Carfilzomib (Kyprolis)]]
 
*[[Carfilzomib (Kyprolis)]]
 +
*[[Carmofur (HCFU)]]
 
*[[Carmustine (BCNU)]]
 
*[[Carmustine (BCNU)]]
 
*[[Carmustine wafer, polifeprosan 20 (Gliadel)]]
 
*[[Carmustine wafer, polifeprosan 20 (Gliadel)]]
−
*[[Caspofungin (Cancidas)]]
 
−
*[[Catumaxomab (Removab)]] '''in US clinical trials'''
 
−
*[[Cediranib (Recentin)]] '''in clinical trials'''
 
 
*[[Cemiplimab (Libtayo)]]
 
*[[Cemiplimab (Libtayo)]]
 
*[[Ceritinib (Zykadia)]]
 
*[[Ceritinib (Zykadia)]]
Line 141: Line 127:
 
*[[Chlorambucil (Leukeran)]]
 
*[[Chlorambucil (Leukeran)]]
 
*[[Chlorozotocin (DCNU)]]
 
*[[Chlorozotocin (DCNU)]]
 +
*[[Ciltacabtagene autoleucel (Carvykti)]]
 
*[[Cisplatin (Platinol)]]
 
*[[Cisplatin (Platinol)]]
−
*[[Cixutumumab (IMC-A12)]] '''in clinical trials'''
 
 
*[[Cladribine (Leustatin)]]
 
*[[Cladribine (Leustatin)]]
 
*[[Clofarabine (Clolar)]]
 
*[[Clofarabine (Clolar)]]
 
*[[Cobimetinib (Cotellic)]]
 
*[[Cobimetinib (Cotellic)]]
−
*[[Coltuximab ravtansine (CoR, SAR3419)]] '''in clinical trials'''
 
 
*[[Copanlisib (Aliqopa)]]
 
*[[Copanlisib (Aliqopa)]]
 
*[[Cortisone]]
 
*[[Cortisone]]
−
*[[Crenolanib (CP-868,596)]] '''in clinical trials'''
 
 
*[[Crizotinib (Xalkori)]]
 
*[[Crizotinib (Xalkori)]]
−
*[[Custirsen (OGX-011)]] '''in clinical trials'''
 
 
*[[Cyclophosphamide (Cytoxan)]]
 
*[[Cyclophosphamide (Cytoxan)]]
 
*[[Cyproterone acetate (Androcur)]]
 
*[[Cyproterone acetate (Androcur)]]
Line 159: Line 142:
  
 
==D==
 
==D==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Dabrafenib (Tafinlar)]]
 
*[[Dabrafenib (Tafinlar)]]
Line 169: Line 149:
 
*[[Dactinomycin (Cosmegen)]]
 
*[[Dactinomycin (Cosmegen)]]
 
*[[Daratumumab (Darzalex)]]
 
*[[Daratumumab (Darzalex)]]
−
*[[Daratumumab and hyaluronidase (Darzalex Faspro)]] '''FDA approved 5/1/2020'''
+
*[[Daratumumab and hyaluronidase (Darzalex Faspro)]]
 +
*[[Daratumumab and vorhyaluronidase (Darzquro)]]
 +
*[[Darinaparsin (Darvias)]]
 
*[[Darolutamide (Nubeqa)]]
 
*[[Darolutamide (Nubeqa)]]
 
*[[Dasatinib (Sprycel)]]
 
*[[Dasatinib (Sprycel)]]
 
*[[Daunorubicin (Cerubidine)]]
 
*[[Daunorubicin (Cerubidine)]]
−
*[[Daunorubicin liposomal (DaunoXome)]]
 
 
*[[Decitabine (Dacogen)]]
 
*[[Decitabine (Dacogen)]]
−
*[[Decitabine and cedazuridine (Inqovi)]] '''FDA approved 7/7/2020'''
+
*[[Decitabine and cedazuridine (Inqovi)]]
 
*[[Degarelix (Firmagon)]]
 
*[[Degarelix (Firmagon)]]
−
*[[Denileukin diftitox (Ontak)]]
 
−
*[[Denintuzumab mafodotin (SGN-CD19A)]] '''in clinical trials'''
 
 
*[[Dexamethasone (Decadron)]]
 
*[[Dexamethasone (Decadron)]]
−
*[[Diethylstilbestrol (DES)]]
 
−
*[[Dinaciclib (SCH 727965)]] '''in clinical trials'''
 
 
*[[Dinutuximab (Unituxin)]]
 
*[[Dinutuximab (Unituxin)]]
−
*[[Discodermolide (XAA296)]] '''in clinical trials'''
+
*[[Dinutuximab beta (Qarziba)]]
−
*[[DMUC5754A]] '''in clinical trials'''
 
 
*[[Docetaxel (Taxotere)]]
 
*[[Docetaxel (Taxotere)]]
−
*[[Dostarlimab (Jemperli)]] '''FDA approved 4/22/2021'''
+
*[[Donafenib (Zepsun)]]
−
*[[Dovitinib (TKI-258)]] '''in clinical trials'''
+
*[[Dostarlimab (Jemperli)]]
 
*[[Doxifluridine (Didox)]]
 
*[[Doxifluridine (Didox)]]
 
*[[Doxorubicin (Adriamycin)]]
 
*[[Doxorubicin (Adriamycin)]]
−
*[[Pegylated liposomal doxorubicin (Doxil)]]
 
 
*[[Durvalumab (Imfinzi)]]
 
*[[Durvalumab (Imfinzi)]]
 
*[[Dutasteride (Avodart)]]
 
*[[Dutasteride (Avodart)]]
Line 196: Line 171:
  
 
==E==
 
==E==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Eflornithine (Iwilfin)]] '''FDA approved 2023-12-13'''
−
|-
+
*[[Elacestrant (Orserdu)]] '''FDA approved 2023-01-27'''
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Edrecolomab (Panorex)]] '''discontinued'''
 
 
*[[Elotuzumab (Empliciti)]]
 
*[[Elotuzumab (Empliciti)]]
 +
*[[Elranatamab (Elrexfio)]] '''FDA approved on 2023-08-14'''
 
*[[Emapalumab (Gamifant)]]
 
*[[Emapalumab (Gamifant)]]
−
*[[Emepepimut-S (Stimuvax)]] '''in clinical trials'''
 
 
*[[Enasidenib (Idhifa)]]
 
*[[Enasidenib (Idhifa)]]
−
*[[Encorafenib (LGX818)]] '''in clinical trials'''
+
*[[Encorafenib (Braftovi)]]
 
*[[Enfortumab vedotin (Padcev)]]
 
*[[Enfortumab vedotin (Padcev)]]
−
*[[Ensartinib (X-396)]] '''in clinical trials'''
+
*[[Ensartinib (Ensacove)]]
−
*[[Entinostat (SNDX-275)]] '''in clinical trials'''
 
−
*[[Entospletinib (GS-9973)]] '''in clinical trials'''
 
 
*[[Entrectinib (Rozlytrek)]]
 
*[[Entrectinib (Rozlytrek)]]
 +
*[[Envafolimab (Enweida)]]
 
*[[Enzalutamide (Xtandi)]]
 
*[[Enzalutamide (Xtandi)]]
 +
*[[Epcoritamab (Epkinly)]] '''FDA approved 2023-05-19'''
 
*[[Epirubicin (Ellence)]]
 
*[[Epirubicin (Ellence)]]
−
*[[Epratuzumab (LymphoCide)]] '''in clinical trials'''
 
 
*[[Erdafitinib (Balversa)]]
 
*[[Erdafitinib (Balversa)]]
 
*[[Eribulin (Halaven)]]
 
*[[Eribulin (Halaven)]]
Line 220: Line 190:
 
*[[Estradiol]]
 
*[[Estradiol]]
 
*[[Estramustine (Emcyt)]]
 
*[[Estramustine (Emcyt)]]
−
*[[Etirinotecan pegol (NKTR-102)]] '''in clinical trials'''
 
 
*[[Etoposide (Vepesid)]]
 
*[[Etoposide (Vepesid)]]
 
*[[Everolimus (Afinitor)]]
 
*[[Everolimus (Afinitor)]]
Line 226: Line 195:
  
 
==F==
 
==F==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Fadrozole (Afema)]]
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Fam-trastuzumab deruxtecan (Enhertu)]]
 
 
*[[Fedratinib (Inrebic)]]
 
*[[Fedratinib (Inrebic)]]
−
*[[Filanesib (ARRY-520)]] '''in clinical trials'''
 
 
*[[Fluorouracil (5-FU)]]
 
*[[Fluorouracil (5-FU)]]
−
*[[Floxuridine (FUDR)]]
 
 
*[[Fludarabine (Fludara)]]
 
*[[Fludarabine (Fludara)]]
−
*[[Flumatinib (HH-GV-678)]] '''in clinical trials'''
+
*[[Flumatinib (Xinfu)]]
−
*[[Fluoxymesterone (Halotestin)]]
 
 
*[[Flutamide (Eulexin)]]
 
*[[Flutamide (Eulexin)]]
−
*[[Folinic acid (Leucovorin)]]
+
*[[Leucovorin (Folinic acid)]]
−
*[[Formestane (Lentaron)]]
+
*[[Forodesine (Fodosine)]]
−
*[[Forodesine (Fodosine)]] '''in clinical trials'''
 
 
*[[Fostamatinib (Tavalisse)]]
 
*[[Fostamatinib (Tavalisse)]]
−
*[[Fotemustine (Muphoran)]] '''in clinical trials'''
+
*[[Fotemustine (Muphoran)]]
−
*[[Fruquintinib (HMPL-013)]] '''in clinical trials'''
+
*[[Fruquintinib (Elunate)]]
 
*[[Fulvestrant (Faslodex)]]
 
*[[Fulvestrant (Faslodex)]]
−
*[[Futibatinib (TAS-120)]] '''in clinical trials'''
+
*[[Furmonertinib (Ivesa)]]
 +
*[[Futibatinib (Lytgobi)]]
  
 
==G==
 
==G==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
−
*[[G207]] '''in clinical trials'''
+
 
−
*[[Galeterone (TOK-001)]] '''in clinical trials'''
+
*[[Gallium Ga 68 gozetotide (Locametz)]]
−
*[[Galunisertib (LY2157299)]] '''in clinical trials'''
 
−
*[[Ganetespib (STA-9090)]] '''in clinical trials'''
 
−
*[[Ganitumab (AMG 479)]] '''in clinical trials'''
 
 
*[[Gefitinib (Iressa)]]
 
*[[Gefitinib (Iressa)]]
 
*[[Gemcitabine (Gemzar)]]
 
*[[Gemcitabine (Gemzar)]]
−
*[[Gemcitabine elaidate (CP-4126, CO-101)]] '''in clinical trials'''
 
 
*[[Gemtuzumab ozogamicin (Mylotarg)]]
 
*[[Gemtuzumab ozogamicin (Mylotarg)]]
 
*[[Gilteritinib (Xospata)]]
 
*[[Gilteritinib (Xospata)]]
 
*[[Glasdegib (Daurismo)]]
 
*[[Glasdegib (Daurismo)]]
−
*[[Glembatumumab vedotin (CDX-011)]]] '''in clinical trials'''
+
*[[Glofitamab (Columvi)]] '''FDA approved 2023-06-15'''
 
*[[Goserelin (Zoladex)]]
 
*[[Goserelin (Zoladex)]]
−
*[[Guadecitabine (SGI-110)]] '''in clinical trials'''
 
  
 
==H==
 
==H==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Heptaplatin (SunPla)]]
−
|-
+
*[[Histamine dihydrochloride (Ceplene)]]
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Heptaplatin (Sunpla)]]
 
−
*[[HER2 peptide vaccine (AE37)]] '''in clinical trials'''
 
 
*[[Histrelin (Vantas)]]
 
*[[Histrelin (Vantas)]]
−
*[[Hu5F9-G4]] '''in clinical trials'''
 
 
*[[Hydrocortisone (Cortef)]]
 
*[[Hydrocortisone (Cortef)]]
 
*[[Hydroxyurea (Hydrea)]]
 
*[[Hydroxyurea (Hydrea)]]
  
 
==I==
 
==I==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Ibritumomab tiuxetan (Zevalin)]]
 
*[[Ibritumomab tiuxetan (Zevalin)]]
Line 293: Line 236:
 
*[[Icotinib (Conmana)]]
 
*[[Icotinib (Conmana)]]
 
*[[Idarubicin (Idamycin)]]
 
*[[Idarubicin (Idamycin)]]
−
*[[Idasanutlin (RG7388)]] '''in clinical trials'''
+
*[[Idecabtagene vicleucel (Abecma)]]
−
*[[Idecabtagene vicleucel (Abecma)]] '''FDA approved 3/26/2021'''
 
 
*[[Idelalisib (Zydelig)]]
 
*[[Idelalisib (Zydelig)]]
 
*[[Ifosfamide (Ifex)]]
 
*[[Ifosfamide (Ifex)]]
−
*[[IMA901]] '''in clinical trials'''
 
 
*[[Imatinib (Gleevec)]]
 
*[[Imatinib (Gleevec)]]
−
*[[Imetelstat (GRN163L)]] '''in clinical trials'''
+
*[[Imetelstat (Rytelo)]] '''FDA approved 2024-06-06'''
−
*[[Indatuximab ravtansine (BT062)]] '''in clinical trials'''
+
*[[Infigratinib (Truseltiq)]]
−
*[[Infigratinib (BGJ398)]] '''in clinical trials'''
 
 
*[[Inotuzumab ozogamicin (Besponsa)]]
 
*[[Inotuzumab ozogamicin (Besponsa)]]
 
*[[Interferon alfa-2a (Roferon-A)]]
 
*[[Interferon alfa-2a (Roferon-A)]]
 
*[[Interferon alfa-2b (Intron-A)]]
 
*[[Interferon alfa-2b (Intron-A)]]
 +
*[[Interferon gamma-1a (Imunomax-γ)]]
 
*[[Interferon gamma-1b (Actimmune)]]
 
*[[Interferon gamma-1b (Actimmune)]]
 
*[[Iobenguane I 131 (Azedra)]]
 
*[[Iobenguane I 131 (Azedra)]]
 
*[[Iodine-131]]
 
*[[Iodine-131]]
−
*[[Ipatasertib (GDC-0068)]] '''in clinical trials'''
 
−
*[[IPH 2101]] '''in clinical trials'''
 
 
*[[Ipilimumab (Yervoy)]]
 
*[[Ipilimumab (Yervoy)]]
−
*[[Iptacopan (LNP023)]]
 
 
*[[Irinotecan (Camptosar)]]
 
*[[Irinotecan (Camptosar)]]
 
*[[Irinotecan liposome (Onivyde)]]
 
*[[Irinotecan liposome (Onivyde)]]
−
*[[Isatuximab (Sarclisa)]] '''FDA approved 3/2/2020'''
+
*[[Isatuximab (Sarclisa)]]
 
*[[Isotretinoin (Accutane)]]
 
*[[Isotretinoin (Accutane)]]
 
*[[Ivosidenib (Tibsovo)]]
 
*[[Ivosidenib (Tibsovo)]]
 
*[[Ixabepilone (Ixempra)]]
 
*[[Ixabepilone (Ixempra)]]
 
*[[Ixazomib (Ninlaro)]]
 
*[[Ixazomib (Ninlaro)]]
−
 
−
==J==
 
−
 
−
*[[JCAR015]] '''in clinical trials'''
 
  
 
==K==
 
==K==
Line 329: Line 263:
  
 
==L==
 
==L==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Lanreotide (Somatuline)]]
 
*[[Lanreotide (Somatuline)]]
 +
*[[Lanreotide LAR (Somatuline Depot)]]
 
*[[Lapatinib (Tykerb)]]
 
*[[Lapatinib (Tykerb)]]
−
*[[Lapuleucel-T (DN24-02)]] '''in clinical trials'''
 
 
*[[Larotrectinib (Vitrakvi)]]
 
*[[Larotrectinib (Vitrakvi)]]
−
*[[Lasofoxifene (Fablyn)]] '''not FDA approved'''
+
*[[Lasofoxifene (Fablyn)]]
 
*[[Lenalidomide (Revlimid)]]
 
*[[Lenalidomide (Revlimid)]]
 
*[[Lenvatinib (Lenvima)]]
 
*[[Lenvatinib (Lenvima)]]
−
*[[Lestaurtinib (CEP-701)]] '''in clinical trials'''
 
−
*[[Letermovir (Prevymis)]]
 
 
*[[Letrozole (Femara)]]
 
*[[Letrozole (Femara)]]
 
*[[Leuprolide (Lupron)]]
 
*[[Leuprolide (Lupron)]]
−
*[[Levamisole (Ergamisol)]] '''discontinued'''
 
 
*[[Levoleucovorin (Fusilev)]]
 
*[[Levoleucovorin (Fusilev)]]
−
*[[Linifanib (ABT-869)]] '''in clinical trials'''
+
*[[Lifileuecel (Contego)]] '''FDA approved 2024-02-16'''
−
*[[Linsitinib (OSI-906)]] '''in clinical trials'''
+
*[[Lisocabtagene maraleucel (Breyanzi)]]
−
*[[Lisocabtagene maraleucel (Breyanzi)]] '''FDA approved 2/5/2021'''
 
 
*[[Lobaplatin (D-19466)]]
 
*[[Lobaplatin (D-19466)]]
 
*[[Lomustine (CCNU)]]
 
*[[Lomustine (CCNU)]]
−
*[[Loncastuximab tesirine (Zynlonta)]] '''FDA approved 4/23/2021'''
+
*[[Loncastuximab tesirine (Zynlonta)]]
 
*[[Lorlatinib (Lorbrena)]]
 
*[[Lorlatinib (Lorbrena)]]
−
*[[Lorvotuzumab mertansine (BB-10901)]] '''in clinical trials'''
+
*[[Lurbinectedin (Zepzelca)]]
−
*[[Lurbinectedin (Zepzelca)]] '''FDA approved 6/15/2020'''
 
 
*[[Lutetium Lu 177 dotatate (Lutathera)]]
 
*[[Lutetium Lu 177 dotatate (Lutathera)]]
−
*[[LY3023414]] '''in clinical trials'''
+
*[[Lutetium Lu 177 vipivotide tetraxetan (Pluvicto)]]
  
 
==M==
 
==M==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
+
*[[Margetuximab (Margenza)]]
−
|[[#top|back to top]]
 
−
|}
 
−
*[[Margetuximab (Margenza)]] '''FDA approved on 12/16/2020'''
 
−
*[[Mapatumumab (HGS-ETR1)]] '''in clinical trials'''
 
−
*[[Masitinib (AB1010)]] '''in clinical trials'''
 
 
*[[Mechlorethamine (Mustargen)]]
 
*[[Mechlorethamine (Mustargen)]]
−
*[[Medroxyprogesterone (MPA)]]
+
*[[Medroxyprogesterone acetate (MPA)]]
 
*[[Megestrol (Megace)]]
 
*[[Megestrol (Megace)]]
 
*[[Melphalan (Alkeran)]]
 
*[[Melphalan (Alkeran)]]
−
*[[Melphalan flufenamide (Pepaxto)]] '''FDA approved on 2/26/2021'''
+
*[[Melphalan for Injection-Hepatic Delivery System (Hepzato Kit)]] '''FDA approved on 2023-08-14'''
 
*[[Mepolizumab (Nucala)]]
 
*[[Mepolizumab (Nucala)]]
 
*[[Mercaptopurine (6-MP)]]
 
*[[Mercaptopurine (6-MP)]]
Line 378: Line 299:
 
*[[Midostaurin (Rydapt)]]
 
*[[Midostaurin (Rydapt)]]
 
*[[Mifamurtide (Mepact)]]
 
*[[Mifamurtide (Mepact)]]
−
*[[Milataxel (TL139)]] '''in clinical trials'''
+
*[[Miriplatin (Miripla)]]
−
*[[Mirvetuximab soravtansine (IMGN853)]] '''in clinical trials'''
+
*[[Mirvetuximab soravtansine (Elahere)]]
−
*[[Mitomycin (Jelmyto)]] '''FDA approved on 4/15/2020'''
+
*[[Mitomycin pyelocalyceal (Jelmyto)]]
 
*[[Mitomycin (Mutamycin)]]
 
*[[Mitomycin (Mutamycin)]]
 
*[[Mitotane (Lysodren)]]
 
*[[Mitotane (Lysodren)]]
 
*[[Mitoxantrone (Novantrone)]]
 
*[[Mitoxantrone (Novantrone)]]
−
*[[MK2206]] '''in clinical trials'''
+
*[[Mobocertinib (Exkivity)]]
−
*[[Mocetinostat (MGCD0103)]] '''in clinical trials'''
 
 
*[[Mogamulizumab (Poteligeo)]]
 
*[[Mogamulizumab (Poteligeo)]]
−
*[[Momelotinib (CYT387)]] '''in clinical trials'''
+
*[[Momelotinib (Ojjaara)]] '''FDA approved 2023-09-15'''
−
*[[MOR208]] '''in clinical trials'''
+
*[[Mosunetuzumab (Lunsumio)]]
−
*[[Motesanib (AMG 706)]] '''in clinical trials'''
 
 
*[[Moxetumomab pasudotox (Lumoxiti)]]
 
*[[Moxetumomab pasudotox (Lumoxiti)]]
  
 
==N==
 
==N==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Nadofaragene firadenovec (Adstiladrin)]]
−
|-
+
*[[Naxitamab (Danyelza)]]
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Naxitamab-gqgk (Danyelza)]] '''FDA approved 11/24/2020'''
 
 
*[[Necitumumab (Portrazza)]]
 
*[[Necitumumab (Portrazza)]]
 
*[[Nedaplatin (Aqupla)]]
 
*[[Nedaplatin (Aqupla)]]
 
*[[Nelarabine (Arranon)]]
 
*[[Nelarabine (Arranon)]]
−
*[[NEOD001]]
 
 
*[[Neratinib (Nerlynx)]]
 
*[[Neratinib (Nerlynx)]]
 
*[[Nilotinib (Tasigna)]]
 
*[[Nilotinib (Tasigna)]]
Line 410: Line 324:
 
*[[Nintedanib (Vargatef)]]
 
*[[Nintedanib (Vargatef)]]
 
*[[Niraparib (Zejula)]]
 
*[[Niraparib (Zejula)]]
 +
*[[Niraparib and abiraterone (Akeega)]] '''FDA approved 2023-08-11'''
 +
*[[Nirogacestat (Ogsiveo)]] '''FDA approved 2023-11-27'''
 
*[[Nivolumab (Opdivo)]]
 
*[[Nivolumab (Opdivo)]]
−
*[[Nolatrexed (Thymitaq)]]
+
*[[Nivolumab and relatlimab (Opdualag)]]
 +
*[[Nogapendekin alfa inbakicept (Anktiva)]] '''FDA approved 2024-04-22'''
 
*[[Non-pegylated liposomal doxorubicin (Myocet)]]
 
*[[Non-pegylated liposomal doxorubicin (Myocet)]]
 
*[[Norethandrolone (Nilevar)]]
 
*[[Norethandrolone (Nilevar)]]
Line 417: Line 334:
  
 
==O==
 
==O==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Obinutuzumab (Gazyva)]]
 
*[[Obinutuzumab (Gazyva)]]
Line 427: Line 340:
 
*[[Ofatumumab (Arzerra)]]
 
*[[Ofatumumab (Arzerra)]]
 
*[[Olaparib (Lynparza)]]
 
*[[Olaparib (Lynparza)]]
−
*[[Olaptesed pegol (NOX-A12)]] '''in clinical trials'''
+
*[[Olutasidenib (Rezlidhia)]]
−
*[[Olaratumab (Lartruvo)]] '''discontinued'''
+
*[[Olverembatinib (HQP-1351)]]
 
*[[Omacetaxine (Synribo)]]
 
*[[Omacetaxine (Synribo)]]
−
*[[Onartuzumab (MetMAb)]] '''in clinical trials'''
 
−
*[[Oprozomib (ONX 0912)]] '''in clinical trials'''
 
−
*[[Orteronel (TAK-700)]] '''in clinical trials'''
 
 
*[[Osimertinib (Tagrisso)]]
 
*[[Osimertinib (Tagrisso)]]
−
*[[Osocimab (BAY 1213790)]] '''in clinical trials'''
 
−
*[[Otlertuzumab (TRU-016)]] '''in clinical trials'''
 
 
*[[Oxaliplatin (Eloxatin)]]
 
*[[Oxaliplatin (Eloxatin)]]
  
 
==P==
 
==P==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Paclitaxel (Taxol)]]
 
*[[Paclitaxel (Taxol)]]
 
*[[Paclitaxel, nanoparticle albumin-bound (Abraxane)]]
 
*[[Paclitaxel, nanoparticle albumin-bound (Abraxane)]]
 
*[[Paclitaxel, polymeric micelle-bound (Genexol-PM)]]
 
*[[Paclitaxel, polymeric micelle-bound (Genexol-PM)]]
−
*[[Pacritinib (SB1518)]] '''in clinical trials'''
+
*[[Pacritinib (Vonjo)]]
 +
*[[Padeliporfin (Tookad)]]
 
*[[Palbociclib (Ibrance)]]
 
*[[Palbociclib (Ibrance)]]
 
*[[Panitumumab (Vectibix)]]
 
*[[Panitumumab (Vectibix)]]
Line 455: Line 361:
 
*[[Peginterferon alfa-2a (Pegasys)]]
 
*[[Peginterferon alfa-2a (Pegasys)]]
 
*[[Peginterferon alfa-2b (Sylatron)]]
 
*[[Peginterferon alfa-2b (Sylatron)]]
 +
*[[Pegylated liposomal doxorubicin (Doxil)]]
 
*[[Pembrolizumab (Keytruda)]]
 
*[[Pembrolizumab (Keytruda)]]
 
*[[Pemetrexed (Alimta)]]
 
*[[Pemetrexed (Alimta)]]
−
*[[Pemigatinib (Pemazyre)]] '''FDA approved 4/17/2020'''
+
*[[Pemigatinib (Pemazyre)]]
 +
*[[Penpulimab (Anniko)]]
 
*[[Pentostatin (Nipent)]]
 
*[[Pentostatin (Nipent)]]
−
*[[Pentraxin 2 (PRM-151)]] '''in clinical trials'''
 
−
*[[Perifosine (KRX-0401)]] '''in clinical trials'''
 
 
*[[Pertuzumab (Perjeta)]]
 
*[[Pertuzumab (Perjeta)]]
 +
*[[Pertuzumab and Trastuzumab hyaluronidase (Phesgo)]]
 
*[[Pexidartinib (Turalio)]]
 
*[[Pexidartinib (Turalio)]]
−
*[[Phosphomannopentaose sulfate (PI-88)]] '''in clinical trials'''
+
*[[Pipobroman (Vercyte)]]
−
*[[Pictilisib (GDC-0941)]] '''in clinical trials'''
 
−
*[[Pidilizumab (CT-011)]] '''in clinical trials'''
 
−
*[[Pinatuzumab vedotin (DCDT2980S)]] '''in clinical trials'''
 
 
*[[Pirarubicin (THP)]]
 
*[[Pirarubicin (THP)]]
−
*[[Pirtobrutinib (LOXO-305)]] '''in clinical trials'''
+
*[[Pirtobrutinib (Jaypirca)]] '''FDA approved 2023-01-27'''
 
*[[Pixantrone (Pixuvri)]]
 
*[[Pixantrone (Pixuvri)]]
−
*[[Plicamycin (Mithracin)]]
 
−
*[[Plinabulin (NPI-2358)]] '''in clinical trials'''
 
 
*[[Polatuzumab vedotin (Polivy)]]
 
*[[Polatuzumab vedotin (Polivy)]]
 
*[[Pomalidomide (Pomalyst)]]
 
*[[Pomalidomide (Pomalyst)]]
 
*[[Ponatinib (Iclusig)]]
 
*[[Ponatinib (Iclusig)]]
 
*[[Porfimer (Photofrin)]]
 
*[[Porfimer (Photofrin)]]
−
*[[Pracinostat (SB939)]] '''in clinical trials'''
 
 
*[[Pralatrexate (Folotyn)]]
 
*[[Pralatrexate (Folotyn)]]
−
*[[Pralsetinib (Gavreto)]] '''FDA approved 9/4/2020'''
+
*[[Pralsetinib (Gavreto)]]
 
*[[Prednisone (Sterapred)]]
 
*[[Prednisone (Sterapred)]]
 
*[[Prednisolone (Millipred)]]
 
*[[Prednisolone (Millipred)]]
 
*[[Procarbazine (Matulane)]]
 
*[[Procarbazine (Matulane)]]
 +
*[[Pyrotinib (Irene)]]
  
 
==Q==
 
==Q==
−
*[[Quisinostat (JNJ-26481585)]] '''in clinical trials'''
+
*[[Quizartinib (Vanflyta)]]
−
*[[Quizartinib (AC220)]] '''in clinical trials'''
 
  
 
==R==
 
==R==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Racotumomab (Vaxira)]]
−
|-
+
*[[Radium-223 (Xofigo)]]
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Radium Ra 223 (Xofigo)]]
 
 
*[[Radotinib (Supect)]]
 
*[[Radotinib (Supect)]]
 
*[[Raltitrexed (Tomudex)]]
 
*[[Raltitrexed (Tomudex)]]
Line 500: Line 397:
 
*[[Ravulizumab (Ultomiris)]]
 
*[[Ravulizumab (Ultomiris)]]
 
*[[Realgar-Indigo naturalis formulation]]
 
*[[Realgar-Indigo naturalis formulation]]
−
*[[Refametinib (BAY 869766)]] '''in clinical trials'''
 
 
*[[Regorafenib (Stivarga)]]
 
*[[Regorafenib (Stivarga)]]
−
*[[Relugolix (Orgovyx)]] '''FDA approved 12/18/2020'''
+
*[[Relugolix (Orgovyx)]]
−
*[[Reovirus (Reolysin)]] '''in clinical trials'''
+
*[[Repotrectinib (Augtyro)]] '''FDA approved 2023-11-15'''
−
*[[Retaspimycin (IPI-504)]] '''in clinical trials'''
+
*[[Retifanlimab (Zynyz)]] '''FDA approved 2023-03-22'''
 
*[[Ribociclib (Kisqali)]]
 
*[[Ribociclib (Kisqali)]]
−
*[[Ricolinostat (ACY-1215, Rocilinostat)]] '''in clinical trials'''
+
*[[Ripretinib (Qinlock)]]
−
*[[Ridaforolimus (AP23573)]] '''in clinical trials'''
 
−
*[[Rilotumumab (AMG 102)]] '''in clinical trials'''
 
−
*[[Ripretinib (Qinlock)]] '''FDA approved 5/15/2020'''
 
 
*[[Rituximab (Rituxan)]]
 
*[[Rituximab (Rituxan)]]
 
**[[Rituximab-abbs (Truxima)]]
 
**[[Rituximab-abbs (Truxima)]]
 +
**[[Rituximab-arrx (Riabni)]]
 
**[[Rituximab-pvvr (Ruxience)]]
 
**[[Rituximab-pvvr (Ruxience)]]
−
*[[Rituximab and hyaluronidase human (Rituximab Hycela)]]
+
**[[Rituximab-blit (Blitzima)]]
−
*[[Rociletinib (CO-1686)]] '''in clinical trials'''
+
**[[Rituximab-rite (Ritemvia)]]
 +
**[[Rituximab-rixa (Rixathon)]]
 +
**[[Rituximab-rixi (Riximyo)]]
 +
*[[Rituximab and hyaluronidase human (Rituxan Hycela)]]
 
*[[Romidepsin (Istodax)]]
 
*[[Romidepsin (Istodax)]]
−
*[[Ropeginterferon alfa-2b (AOP2014)]] '''in clinical trials'''
+
*[[Ropeginterferon alfa-2b (Besremi)]]
 
*[[Rucaparib (Rubraca)]]
 
*[[Rucaparib (Rubraca)]]
 
*[[Ruxolitinib (Jakafi)]]
 
*[[Ruxolitinib (Jakafi)]]
  
 
==S==
 
==S==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
−
*[[Sacituzumab govitecan (Trodelvy)]] '''FDA approved 4/22/2020'''
+
 
 +
*[[Sacituzumab govitecan (Trodelvy)]]
 
*[[Samarium-153 (Quadramet)]]
 
*[[Samarium-153 (Quadramet)]]
−
*[[Sapacitabine (CS-682)]] '''in clinical trials'''
 
−
*[[Sapanisertib (MLN0128)]] '''in clinical trials'''
 
−
*[[Seliciclib (CYC202)]] '''in clinical trials'''
 
 
*[[Selinexor (Xpovio)]]
 
*[[Selinexor (Xpovio)]]
−
*[[Selpercatinib (Retevmo)]] '''FDA approved 5/8/2020'''
+
*[[Selpercatinib (Retevmo)]]
−
*[[Selumetinib (Koselugo)]] '''FDA approved 4/10/2020'''
+
*[[Selumetinib (Koselugo)]]
−
*[[Semuloparin (AVE5026)]] '''in clinical trials'''
+
*[[Serplulimab (Hansizhuang)]]
−
*[[Semustine (MeCCNU)]]
+
*[[Sintilimab (Tyvyt)]]
−
*[[Sintilimab (IBI 308)]] '''in clinical trials'''
 
 
*[[Sipuleucel-T (Provenge)]]
 
*[[Sipuleucel-T (Provenge)]]
 +
*[[Sirolimus protein-bound particles (Fyarro)]]
 
*[[Sonidegib (Odomzo)]]
 
*[[Sonidegib (Odomzo)]]
 
*[[Sorafenib (Nexavar)]]
 
*[[Sorafenib (Nexavar)]]
−
*[[Sotorasib (AMG 510)]] '''in clinical trials'''
+
*[[Sotorasib (Lumakras)]]
−
*[[Spebrutinib (CC-292)]] '''in clinical trials'''
 
 
*[[Stilbamidine]]
 
*[[Stilbamidine]]
 
*[[Streptozocin (Zanosar)]]
 
*[[Streptozocin (Zanosar)]]
 
*[[Strontium-89 (Metastron)]]
 
*[[Strontium-89 (Metastron)]]
 +
*[[Sugemalimab (Cejemly)]]
 
*[[Sunitinib (Sutent)]]
 
*[[Sunitinib (Sutent)]]
−
*[[Surufatinib (HMPL-012)]] '''in clinical trials'''
+
*[[Suramin (Antrypol)]]
−
*[[Sutimlimab (BIVV009)]] '''in clinical trials'''
 
  
 
==T==
 
==T==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Tabelecleucel (Ebvallo)]]
−
|-
+
*[[Tafasitamab (Monjuvi)]]
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Tabalumab (LY2127399)]] '''in clinical trials'''
 
−
*[[Tafasitamab (Monjuvi)]] '''FDA approved 7/31/2020'''
 
 
*[[Tagraxofusp (Elzonris)]]
 
*[[Tagraxofusp (Elzonris)]]
 
*[[Talazoparib (Talzenna)]]
 
*[[Talazoparib (Talzenna)]]
 
*[[Talimogene laherparepvec (Imlygic)]]
 
*[[Talimogene laherparepvec (Imlygic)]]
−
*[[Tamibarotene (Amnoid)]] '''in clinical trials'''
+
*[[Taloporfin (Laserphyrin)]]
 +
*[[Talquetamab (Talvey)]] '''FDA approved 2023-08-09'''
 +
*[[Tamibarotene (Amnoid)]]
 
*[[Tamoxifen (Nolvadex)]]
 
*[[Tamoxifen (Nolvadex)]]
−
*[[Tazemetostat (Tazverik)]] '''FDA approved 1/23/2020'''
+
*[[Tarlatamab (Imdelltra)]] '''FDA approved 2024-05-16'''
 +
*[[Tasonermin (Beromun)]]
 +
*[[Tazemetostat (Tazverik)]]
 +
*[[Tebentafusp (Kimmtrak)]]
 +
*[[Teclistamab (Tecvayli)]]
 
*[[Tegafur and uracil (UFT)]]
 
*[[Tegafur and uracil (UFT)]]
 
*[[Tegafur, gimeracil, oteracil (Teysuno, S-1)]]
 
*[[Tegafur, gimeracil, oteracil (Teysuno, S-1)]]
−
*[[Telotristat (Xermelo)]]
+
*[[Temoporfin (Foscan)]]
 
*[[Temozolomide (Temodar)]]
 
*[[Temozolomide (Temodar)]]
 
*[[Temsirolimus (Torisel)]]
 
*[[Temsirolimus (Torisel)]]
 
*[[Teniposide (Vumon)]]
 
*[[Teniposide (Vumon)]]
−
*[[Tepotinib (Tepmetko)]] '''FDA approved 2/3/2021'''
+
*[[Tepotinib (Tepmetko)]]
−
*[[Tesetaxel (DJ-927)]] '''in clinical trials'''
 
−
*[[Tesevatinib (XL647)]] '''in clinical trials'''
 
−
*[[Testolactone (Teslac)]] '''discontinued'''
 
 
*[[Thalidomide (Thalomid)]]
 
*[[Thalidomide (Thalomid)]]
 
*[[Thioguanine (Tabloid)]]
 
*[[Thioguanine (Tabloid)]]
 
*[[Thiotepa (Tepadina)]]
 
*[[Thiotepa (Tepadina)]]
 
*[[Thiotepa (Thioplex)]]
 
*[[Thiotepa (Thioplex)]]
−
*[[Tigatuzumab (CS-1008)]] '''in clinical trials'''
+
*[[Tirabrutinib (Velexbru)]]
−
*[[Tipifarnib (Zarnestra)]] '''in clinical trials'''
 
−
*[[Tirabrutinib (GS-4059)]] '''in clinical trials'''
 
 
*[[Tisagenlecleucel (Kymriah)]]
 
*[[Tisagenlecleucel (Kymriah)]]
−
*[[Tisotumab vedotin (HuMax-TF-ADC)]] '''in clinical trials'''
+
*[[Tisotumab vedotin (Tivdak)]]
−
*[[Tivantinib (ARQ 197)]] '''in clinical trials'''
 
−
*[[Tivozanib (AV-951)]] '''in clinical trials'''
 
 
*[[Topotecan (Hycamtin)]]
 
*[[Topotecan (Hycamtin)]]
 
*[[Toremifene (Fareston)]]
 
*[[Toremifene (Fareston)]]
−
*[[Tosedostat (CHR-2797)]] '''in clinical trials'''
+
*[[Toripalimab (Loqtorzi)]] '''FDA approved 2023-10-27'''
 
*[[Tositumomab and I-131 (Bexxar)]]
 
*[[Tositumomab and I-131 (Bexxar)]]
 +
*[[Tovorafenib (Ojemda)]] '''FDA approved 2024-04-23'''
 
*[[Trabectedin (Yondelis)]]
 
*[[Trabectedin (Yondelis)]]
 
*[[Trametinib (Mekinist)]]
 
*[[Trametinib (Mekinist)]]
Line 594: Line 479:
 
**[[Trastuzumab-dkst (Ogivri)]]
 
**[[Trastuzumab-dkst (Ogivri)]]
 
**[[Trastuzumab-dttb (Ontruzant)]]
 
**[[Trastuzumab-dttb (Ontruzant)]]
 +
**[[Trastuzumab-herw (Herwenda)]]
 
**[[Trastuzumab-pkrb (Herzuma)]]
 
**[[Trastuzumab-pkrb (Herzuma)]]
 
**[[Trastuzumab-qyyp (Trazimera)]]
 
**[[Trastuzumab-qyyp (Trazimera)]]
 +
**[[Trastuzumab-strf (Hercessi)]] '''FDA approved 2024-04-29'''
 +
**[[Trastuzumab-zerc (Zercepac)]]
 
*[[Trastuzumab and hyaluronidase (Herceptin Hylecta)]]
 
*[[Trastuzumab and hyaluronidase (Herceptin Hylecta)]]
−
*[[Trebananib (AMG 386)]] '''in clinical trials'''
+
*[[Trastuzumab deruxtecan (Enhertu)]]
−
*[[Tremelimumab (ticilimumab)]] '''in clinical trials'''
+
*[[Trastuzumab emtansine (Kadcyla)]]
 +
*[[Tremelimumab (Imjudo)]]
 
*[[Treosulfan (Ovastat)]]
 
*[[Treosulfan (Ovastat)]]
 
*[[Trifluridine and tipiracil (Lonsurf)]]
 
*[[Trifluridine and tipiracil (Lonsurf)]]
Line 604: Line 493:
 
*[[Trimetrexate (Neutrexin)]]
 
*[[Trimetrexate (Neutrexin)]]
 
*[[Triptorelin (Trelstar LA)]]
 
*[[Triptorelin (Trelstar LA)]]
−
*[[Tucatinib (Tukysa)]] '''FDA approved 4/17/2020'''
+
*[[Trofosfamide (Ixoten)]]
 +
*[[Tucatinib (Tukysa)]]
  
 
==U==
 
==U==
−
 
+
*[[Ublituximab (Briumvi)]] '''FDA approved 2023-01-06'''
−
*[[Ublituximab (TG-1101)]] '''in clinical trials'''
 
−
*[[UCART19]] '''in clinical trials'''
 
−
*[[Umbralisib (Ukoniq)]] '''FDA approved 2/5/2021'''
 
−
*[[Uracil mustard]]
 
−
*[[Urethane]]
 
−
 
 
 
==V==
 
==V==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Valemetostat (Ezharmia)]]
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
−
*[[Vadastuximab talirine (SGN-CD33A)]] '''in clinical trials'''
 
 
*[[Valrubicin (Valstar)]]
 
*[[Valrubicin (Valstar)]]
 
*[[Vandetanib (Caprelsa)]]
 
*[[Vandetanib (Caprelsa)]]
−
*[[Varlilumab (CDX-1127)]] '''in clinical trials'''
 
−
*[[Veliparib (ABT-888)]] '''in clinical trials'''
 
−
*[[Veltuzumab (hA20)]] '''in clinical trials'''
 
 
*[[Vemurafenib (Zelboraf)]]
 
*[[Vemurafenib (Zelboraf)]]
 
*[[Venetoclax (Venclexta)]]
 
*[[Venetoclax (Venclexta)]]
 
*[[Vinblastine (Velban)]]
 
*[[Vinblastine (Velban)]]
 
*[[Vincristine (Oncovin)]]
 
*[[Vincristine (Oncovin)]]
−
*[[Vincristine liposomal (Marqibo)]]
 
 
*[[Vindesine (Eldisine)]]
 
*[[Vindesine (Eldisine)]]
 
*[[Vinflunine (Javlor)]]
 
*[[Vinflunine (Javlor)]]
 
*[[Vinorelbine (Navelbine)]]
 
*[[Vinorelbine (Navelbine)]]
 
*[[Vismodegib (Erivedge)]]
 
*[[Vismodegib (Erivedge)]]
−
*[[Volasertib (BI 6727)]] '''in clinical trials'''
 
 
*[[Vorinostat (Zolinza)]]
 
*[[Vorinostat (Zolinza)]]
−
*[[Vosaroxin (SNS 595)]] '''in clinical trials'''
 
 
*[[Voxelotor (Oxbryta)]]
 
*[[Voxelotor (Oxbryta)]]
−
*[[Voxtalisib (XL765)]] '''in clinical trials'''
 
  
 
==Z==
 
==Z==
−
*[[Zandelisib (ME-401)]] '''in clinical trials'''
+
 
 
*[[Zanubrutinib (Brukinsa)]]
 
*[[Zanubrutinib (Brukinsa)]]
 +
*[[Zimberelimab (Yu Duo)]]
 
*[[Ziv-aflibercept (Zaltrap)]]
 
*[[Ziv-aflibercept (Zaltrap)]]
 +
**[[Aflibercept-jbvf (Yesafili)]] '''FDA approved 2024-05'''
 +
**[[Aflibercept-yszy (Opuviz)]] '''FDA approved 2024-05'''
 +
 +
=Discontinued antineoplastics=
 +
''This section contains drugs that have had at least one formal approval in any domain (FDA, EMA, etc), but are no longer on the market. Note that it is possible that these drugs continue to be available in some limited way, such as through compassionate use programs.
 +
 +
==A==
 +
 +
*[[Aminopterin]]
 +
*[[Asparaginase (Elspar)]]
 +
 +
==D==
 +
 +
*[[Daunorubicin liposomal (DaunoXome)]]
 +
*[[Denileukin diftitox (Ontak)]]
 +
*[[Diethylstilbestrol (DES)]]
 +
 +
==E==
 +
 +
*[[Edrecolomab (Panorex)]]
 +
*[[Ethinylestradiol]]
 +
 +
==F==
 +
 +
*[[Floxuridine (FUDR)]]
 +
*[[Fluoxymesterone (Halotestin)]]
 +
*[[Formestane (Lentaron)]]
 +
 +
==L==
 +
 +
*[[Levamisole (Ergamisol)]]
 +
 +
==M==
 +
 +
*[[Melphalan flufenamide (Pepaxto)]]
 +
 +
==O==
 +
 +
*[[Olaratumab (Lartruvo)]]
 +
 +
==P==
 +
*[[Paclitaxel poliglumex (Opaxio)]]
 +
*[[Plicamycin (Mithracin)]]
 +
*[[Polyestradiol phosphate (Estradurin)]]
 +
 +
==S==
 +
 +
*[[Semustine (MeCCNU)]]
 +
 +
==T==
 +
*[[Testolactone (Teslac)]]
 +
*[[Triethylenemelamine (Tretamine)]]
 +
 +
==U==
 +
*[[Umbralisib (Ukoniq)]]
 +
*[[Uracil mustard]]
 +
*[[Urethane]]
 +
 +
==V==
 +
*[[Vincristine liposomal (Marqibo)]]
 +
 +
=Investigational antineoplastics=
 +
''This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.''
 +
==A==
 +
 +
*[[Abexinostat (PCI-24781)]]
 +
*[[Actinium Ac 225 lintuzumab (Actimab-A)]]
 +
*[[Adavosertib (MK-1775)]]
 +
*[[Adebrelimab (SHR-1316)]]
 +
*[[Adenovirus-interferon-γ (TG-1042)]]
 +
*[[Afamitresgene Autoleucel (ADP-A2M4)]]
 +
*[[Afuresertib (GSK-2110183)]]
 +
*[[Agatolimod (PF-3512676)]]
 +
*[[Alisertib (MLN-8237)]]
 +
*[[Amatuximab (MORAb-009)]]
 +
*[[Amonafide (Quinamed)]]
 +
*[[Apocept (APG-101)]]
 +
*[[Astuprotimut-R (GSK-1572932A)]]
 +
 +
==B==
 +
 +
*[[Barasertib (AZD-1152)]]
 +
*[[Bavituximab (PGN-401)]]
 +
*[[Befotertinib (D-0316)]]
 +
*[[Belagenpumatucel-L (Lucanix)]]
 +
*[[BE-CAR7]]
 +
*[[BHQ-880]]
 +
*[[Birtamimab (NEOD-001)]]
 +
*[[BL22 immunotoxin (CAT-3888)]]
 +
*[[Buparlisib (BKM-120)]]
 +
 +
==C==
 +
*[[CARv3-TEAM-E T-cells]]
 +
*[[Catumaxomab (Removab)]] '''in US clinical trials'''
 +
*[[Cediranib (Recentin)]]
 +
*[[Cixutumumab (IMC-A12)]]
 +
*[[Coltuximab ravtansine (SAR-3419)]]
 +
*[[Crenolanib (CP-868,596)]]
 +
*[[Custirsen (OGX-011)]]
 +
 +
==D==
 +
 +
*[[Dalpiciclib (SHR-6390)]]
 +
*[[Danicopan (ALXN-2040)]]
 +
*[[Datopotamab deruxtecan (DS-1062)]]
 +
*[[Denintuzumab mafodotin (SGN-CD19A)]]
 +
*[[Dinaciclib (SCH-727965)]]
 +
*[[Divarasib (GDC-6036)]]
 +
*[[Discodermolide (XAA-296)]]
 +
*[[DMUC-5754A]]
 +
*[[Dovitinib (TKI-258)]]
 +
 +
==E==
 +
*[[Emepepimut-S (Stimuvax)]]
 +
*[[Eluvixtamab (AMG-330)]]
 +
*[[Entinostat (SNDX-275)]]
 +
*[[Entospletinib (GS-9973)]]
 +
*[[Envonalkib (TQ-B3139)]]
 +
*[[Epratuzumab (LymphoCide)]]
 +
*[[Etirinotecan pegol (NKTR-102)]]
 +
 +
==F==
 +
*[[Farletuzumab (MORAb-003)]]
 +
*[[Figitumumab (CP-751,871)]]
 +
*[[Filanesib (ARRY-520)]]
 +
 +
==G==
 +
*[[G207]]
 +
*[[Galeterone (TOK-001)]]
 +
*[[Galunisertib (LY-2157299)]]
 +
*[[Ganetespib (STA-9090)]]
 +
*[[Ganitumab (AMG-479)]]
 +
*[[GD2-CART01]]
 +
*[[Gemcitabine elaidate (CP-4126)]]
 +
*[[Glembatumumab vedotin (CDX-011)]]
 +
*[[Guadecitabine (SGI-110)]]
 +
 +
==H==
 +
 +
*[[HER2 peptide vaccine (AE37)]]
 +
*[[Hu5F9-G4]]
 +
 +
==I==
 +
 +
*[[Idasanutlin (RG-7388)]]
 +
*[[IMA-901]]
 +
*[[Indatuximab ravtansine (BT-062)]]
 +
*[[Ipatasertib (GDC-0068)]]
 +
*[[IPH-2101]]
 +
 +
==J==
 +
 +
*[[JCAR015]]
 +
 +
==L==
 +
 +
*[[Lapuleucel-T (DN24-02)]]
 +
*[[Lestaurtinib (CEP-701)]]
 +
*[[Linifanib (ABT-869)]]
 +
*[[Linsitinib (OSI-906)]]
 +
*[[Lorvotuzumab mertansine (BB-10901)]]
 +
*[[Lutetium-177-PSMA-617]]
 +
*[[LY-3023414]]
 +
 +
==M==
 +
*[[Magrolimab (Hu5F9-G4)]]
 +
*[[Mapatumumab (HGS-ETR1)]]
 +
*[[Masitinib (AB-1010)]]
 +
*[[MCARH-109]]
 +
*[[Mezigdomide (BMS-986348)]]
 +
*[[Milataxel (TL-139)]]
 +
*[[MK-2206]]
 +
*[[Mocetinostat (MGCD-0103)]]
 +
*[[Motesanib (AMG-706)]]
 +
 +
==N==
 +
*[[Nolatrexed (Thymitaq)]]
 +
 +
==O==
 +
*[[Oblimersen (Genasense)]]
 +
*[[Olaptesed pegol (NOX-A12)]]
 +
*[[Onartuzumab (MetMAb)]]
 +
*[[Oprozomib (ONX-0912)]]
 +
*[[Orteronel (TAK-700)]]
 +
*[[Osocimab (BAY-1213790)]]
 +
*[[Otlertuzumab (TRU-016)]]
 +
 +
==P==
 +
*[[Patritumab deruxtecan (U3-1402)]]
 +
*[[Pentraxin 2 (PRM-151)]]
 +
*[[Perifosine (KRX-0401)]]
 +
*[[Phosphomannopentaose sulfate (PI-88)]]
 +
*[[Pictilisib (GDC-0941)]]
 +
*[[Pidilizumab (CT-011)]]
 +
*[[Pimitespib (TAS-116)]]
 +
*[[Pinatuzumab vedotin (DCDT-2980S)]]
 +
*[[Plinabulin (NPI-2358)]]
 +
*[[Pracinostat (SB-939)]]
 +
 +
==Q==
 +
*[[Quisinostat (JNJ-26481585)]]
 +
 +
==R==
 +
*[[Rebimastat (BMS-275291)]]
 +
*[[Refametinib (BAY-869766)]]
 +
*[[Reovirus (Reolysin)]]
 +
*[[Retaspimycin (IPI-504)]]
 +
*[[Revumenib (SNDX-5613)]]
 +
*[[Rezvilutamide (SHR-3680)]]
 +
*[[Ricolinostat (ACY-1215)]]
 +
*[[Ridaforolimus (AP-23573)]]
 +
*[[Rilotumumab (AMG-102)]]
 +
*[[Ripertamab (SCT-400)]]
 +
*[[Rociletinib (CO-1686)]]
 +
 +
==S==
 +
 +
*[[Sapacitabine (CS-682)]]
 +
*[[Sapanisertib (MLN-0128)]]
 +
*[[Seliciclib (CYC-202)]]
 +
*[[Semuloparin (AVE-5026)]]
 +
*[[Spebrutinib (CC-292)]]
 +
*[[Surufatinib (HMPL-012)]]
 +
 +
==T==
 +
 +
*[[Tabalumab (LY-2127399)]]
 +
*[[Tasadenoturev (DNX-2401)]]
 +
*[[Telisotuzumab vedotin (ABBV-399)]]
 +
*[[Tertomotide (GV-1001)]]
 +
*[[Tesetaxel (DJ-927)]]
 +
*[[Tesevatinib (XL-647)]]
 +
*[[Tigatuzumab (CS-1008)]]
 +
*[[Tipifarnib (Zarnestra)]]
 +
*[[Tirapazamine (Tirazone)]]
 +
*[[Tislelizumab (Baizean)]]
 +
*[[Tivantinib (ARQ-197)]]
 +
*[[Tivozanib (AV-951)]]
 +
*[[Tosedostat (CHR-2797)]]
 +
*[[Trebananib (AMG-386)]]
 +
*[[Tusamitamab ravtansine (SAR-408701)]]
 +
 +
==U==
 +
*[[UCART19]]
 +
 +
==V==
 +
 +
*[[Vadastuximab talirine (SGN-CD33A)]]
 +
*[[Vadimezan (AS-A404)]]
 +
*[[Varlilumab (CDX-1127)]]
 +
*[[Veliparib (ABT-888)]]
 +
*[[Veltuzumab (hA20)]]
 +
*[[Volasertib (BI-6727)]]
 +
*[[Vorasidenib (AG-881)]]
 +
*[[Vorolanib (CM-082)]]
 +
*[[Vosaroxin (SNS-595)]]
 +
*[[Voxtalisib (XL-765)]]
 +
 +
==Z==
 +
 +
*[[Zandelisib (ME-401)]]
 +
*[[Zolbetuximab (IMAB-362)]]
  
 
=Supportive and other medications=
 
=Supportive and other medications=
 +
''This section contains supportive drugs that are either approved or investigational. Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound.''
 +
==A==
  
−
==A==
 
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Abciximab (ReoPro)]]
 
*[[Abciximab (ReoPro)]]
 
*[[Acetaminophen (Tylenol)]]
 
*[[Acetaminophen (Tylenol)]]
 
*[[Acetazolamide (Diamox)]]
 
*[[Acetazolamide (Diamox)]]
 
*[[Acyclovir (Zovirax)]]
 
*[[Acyclovir (Zovirax)]]
 +
*[[ADAMTS13, recombinant (Adzynma)]]
 
*[[Alendronate (Fosamax)]]
 
*[[Alendronate (Fosamax)]]
 
*[[Alizapride (Litican)]]
 
*[[Alizapride (Litican)]]
Line 664: Line 797:
 
*[[Amoxicillin]]
 
*[[Amoxicillin]]
 
*[[Anagrelide (Agrylin)]]
 
*[[Anagrelide (Agrylin)]]
 +
*[[Andexanet alfa (Andexxa)]]
 
*[[Anti-inhibitor coagulant complex (FEIBA NF)]]
 
*[[Anti-inhibitor coagulant complex (FEIBA NF)]]
 
*[[Antithrombin III (human and recombinant)]]
 
*[[Antithrombin III (human and recombinant)]]
Line 682: Line 816:
  
 
==B==
 
==B==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
*[[Betibeglogene autotemcel (Zynteglo)]]
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Betrixaban (Bevyxxa)]]
 
*[[Betrixaban (Bevyxxa)]]
 
*[[Bismuth subsalicylate (Pepto-Bismol)]]
 
*[[Bismuth subsalicylate (Pepto-Bismol)]]
Line 691: Line 822:
  
 
==C==
 
==C==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Cangrelor (Kengreal)]]
 
*[[Cangrelor (Kengreal)]]
 
*[[Calcium phosphate rinse (Caphosol)]]
 
*[[Calcium phosphate rinse (Caphosol)]]
 +
*[[Caspofungin (Cancidas)]]
 
*[[Cetirizine (Zyrtec)]]
 
*[[Cetirizine (Zyrtec)]]
 
*[[Chlorpheniramine (Chlor-Trimeton)]]
 
*[[Chlorpheniramine (Chlor-Trimeton)]]
Line 706: Line 835:
 
*[[Clodronate (Bonefos)]]
 
*[[Clodronate (Bonefos)]]
 
*[[Clopidogrel (Plavix)]]
 
*[[Clopidogrel (Plavix)]]
 +
*[[Concizumab (Alhemo)]]
 
*[[Crizanlizumab (Adakveo)]]
 
*[[Crizanlizumab (Adakveo)]]
 
*[[Cyanocobalamin (Vitamin B12)]]
 
*[[Cyanocobalamin (Vitamin B12)]]
−
*[[Cyclosporine modified (Neoral)]]
+
*[[Cyclosporine]]
−
*[[Cyclosporine non-modified (Sandimmune)]]
 
 
*[[Cytomegalovirus Immune Globulin (Cytogam)]]
 
*[[Cytomegalovirus Immune Globulin (Cytogam)]]
  
 
==D==
 
==D==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Dabigatran (Pradaxa)]]
 
*[[Dabigatran (Pradaxa)]]
 
*[[Dalteparin (Fragmin)]]
 
*[[Dalteparin (Fragmin)]]
Line 728: Line 854:
 
*[[Defibrotide (Defitelio)]]
 
*[[Defibrotide (Defitelio)]]
 
*[[Denosumab (Xgeva)]]
 
*[[Denosumab (Xgeva)]]
 +
**[[Denosumab-bddz (Wyost)]]
 
*[[Desmopressin (DDAVP)]]
 
*[[Desmopressin (DDAVP)]]
 
*[[Dexchlorpheniramine (Polaramine)]]
 
*[[Dexchlorpheniramine (Polaramine)]]
Line 740: Line 867:
  
 
==E==
 
==E==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Eculizumab (Soliris)]]
 
*[[Eculizumab (Soliris)]]
 +
**[[Eculizumab-beke (Bekemv)]]
 +
**[[Eculizumab-epys (Epysqli)]]
 
*[[Edoxaban (Savaysa)]]
 
*[[Edoxaban (Savaysa)]]
 +
*[[Efanesoctocog alfa (Altuviiio)]]
 +
*[[Eflapegrastim (Rolvedon)]]
 
*[[Eltrombopag (Promacta)]]
 
*[[Eltrombopag (Promacta)]]
−
*[[Emicizumab-kxwh (Hemlibra)]]
+
*[[Emicizumab (Hemlibra)]]
 
*[[Enoxaparin (Lovenox)]]
 
*[[Enoxaparin (Lovenox)]]
 +
**[[Enoxaparin-inhi (Inhixa)]]
 
*[[Epoetin alfa (Procrit)]]
 
*[[Epoetin alfa (Procrit)]]
−
*[[Epoetin alfa-epbx (Retacrit)]]
+
**[[Epoetin alfa-epbx (Retacrit)]]
 +
**[[Epoetin alfa-abse (Abseamed)]]
 +
**[[Epoetin alfa-bino (Binocrit)]]
 +
**[[Epoetin alfa-hexa (Epoetin Alfa Hexal)]]
 +
*[[Epoetin theta (Biopoin)]]
 +
*[[Epoetin zeta (Eprex)]]
 +
**[[Epoetin zeta-reta (Retacrit)]]
 +
**[[Epoetin zeta-sila (Silapo)]]
 
*[[Eptifibatide (Integrilin)]]
 
*[[Eptifibatide (Integrilin)]]
 +
*[[Etranacogene dezaparvovec (Hemgenix)]]
 +
*[[Exagamglogene autotemcel (Casgevy)]] '''FDA approved on 2023-12-08'''
  
 
==F==
 
==F==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Factor VIIa, recombinant (NovoSeven RT)]]
 
*[[Factor VIIa, recombinant (NovoSeven RT)]]
 
*[[Factor VIII, human]]
 
*[[Factor VIII, human]]
Line 765: Line 899:
 
*[[Factor IX, recombinant, Fc fusion protein (Alprolix)]]
 
*[[Factor IX, recombinant, Fc fusion protein (Alprolix)]]
 
*[[Factor X, human (Coagadex)]]
 
*[[Factor X, human (Coagadex)]]
−
*[[Factor Xa, recombinant, inactivated-zhzo (Andexxa)]]
 
 
*[[Factor XIII concentrate, human (Corifact)]]
 
*[[Factor XIII concentrate, human (Corifact)]]
 
*[[Famciclovir (Famvir)]]
 
*[[Famciclovir (Famvir)]]
 
*[[Famotidine (Pepcid)]]
 
*[[Famotidine (Pepcid)]]
 
*[[Ferric carboxymaltose (Injectafer)]]
 
*[[Ferric carboxymaltose (Injectafer)]]
 +
*[[Ferric derisomaltose (Monoferric)]]
 
*[[Ferric gluconate (Ferrlecit)]]
 
*[[Ferric gluconate (Ferrlecit)]]
 
*[[Ferrous sulfate (Feosol)]]
 
*[[Ferrous sulfate (Feosol)]]
Line 776: Line 910:
 
*[[Filgrastim (Neupogen)]]
 
*[[Filgrastim (Neupogen)]]
 
**[[Filgrastim-aafi (Nivestym)]]
 
**[[Filgrastim-aafi (Nivestym)]]
 +
**[[Filgrastim-ayow (Releuko)]]
 
**[[Filgrastim-sndz (Zarxio)]]
 
**[[Filgrastim-sndz (Zarxio)]]
 +
**[[Filgrastim-acco (Accofil)]]
 +
**[[Filgrastim-hexa (Filgrastim Hexal)]]
 +
**[[Filgrastim-gras (Grastofil)]]
 +
**[[Filgrastim-rati (Ratiograstim)]]
 +
**[[Filgrastim-teva (Tevagrastim)]]
 
*[[Finasteride (Proscar)]]
 
*[[Finasteride (Proscar)]]
 +
*[[Fitusiran (ALN-AT3SC)]]
 
*[[Fluconazole (Diflucan)]]
 
*[[Fluconazole (Diflucan)]]
 
*[[Folic acid (Folate)]]
 
*[[Folic acid (Folate)]]
 
*[[Fondaparinux (Arixtra)]]
 
*[[Fondaparinux (Arixtra)]]
 
*[[Fosaprepitant (Emend for Injection)]]
 
*[[Fosaprepitant (Emend for Injection)]]
 +
*[[Fosnetupitant (Arokaris)]]
 
*[[Furosemide (Lasix)]]
 
*[[Furosemide (Lasix)]]
  
 
==G==
 
==G==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Glucarpidase (Voraxaze)]]
 
*[[Glucarpidase (Voraxaze)]]
−
*[[Granisetron (Kytril)]]
+
*[[Granisetron]]
−
*[[Granisetron (Sancuso)]]
 
−
*[[Granisetron (Sustol)]]
 
  
 
==H==
 
==H==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Haloperidol (Haldol)]]
 
*[[Haloperidol (Haldol)]]
 
*[[Hematopoetic progenitor cells, cord blood (Hemacord)]]
 
*[[Hematopoetic progenitor cells, cord blood (Hemacord)]]
  
 
==I==
 
==I==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Ibandronate (Boniva)]]
 
*[[Ibandronate (Boniva)]]
 
*[[Idarucizumab (Praxbind)]]
 
*[[Idarucizumab (Praxbind)]]
 
*[[Indomethacin (Indocin)]]
 
*[[Indomethacin (Indocin)]]
 +
*[[Iptacopan (Fabhalta)]] '''FDA approved 2023-12-05'''
 
*[[Iron dextran (INFeD)]]
 
*[[Iron dextran (INFeD)]]
 
*[[Iron sucrose (Venofer)]]
 
*[[Iron sucrose (Venofer)]]
Line 815: Line 947:
  
 
==L==
 
==L==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Lactulose]]
 
*[[Lactulose]]
 
*[[Lamivudine (Epivir)]]
 
*[[Lamivudine (Epivir)]]
Line 824: Line 953:
 
*[[Lenograstim (Granocyte)]]
 
*[[Lenograstim (Granocyte)]]
 
*[[Lepirudin (Refludan)]] '''discontinued'''
 
*[[Lepirudin (Refludan)]] '''discontinued'''
 +
*[[Letermovir (Prevymis)]]
 
*[[Levofloxacin (Levaquin)]]
 
*[[Levofloxacin (Levaquin)]]
 
*[[L-glutamine (Endari)]]
 
*[[L-glutamine (Endari)]]
−
*[[Lipefilgrastim (XM22)]] '''in clinical trials'''
+
*[[Lipefilgrastim (Lonquex)]]
 
*[[Loperamide (Imodium)]]
 
*[[Loperamide (Imodium)]]
 
*[[Lorazepam (Ativan)]]
 
*[[Lorazepam (Ativan)]]
 +
*[[Lovotibeglogene autotemcel (Lyfgenia)]] '''FDA approved on 2023-12-08'''
 
*[[Luspatercept (Reblozyl)]]
 
*[[Luspatercept (Reblozyl)]]
 
*[[Lusutrombopag (Mulpleta)]]
 
*[[Lusutrombopag (Mulpleta)]]
  
 
==M==
 
==M==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Mannitol]]
 
*[[Mannitol]]
Line 843: Line 971:
 
*[[Methyltesterone (Android)]]
 
*[[Methyltesterone (Android)]]
 
*[[Metoclopramide (Reglan)]]
 
*[[Metoclopramide (Reglan)]]
 +
*[[Mitapivat (Pyrukynd)]]
 +
*[[Motixafortide (Aphexda)]] '''FDA approved 2023-09'''
 
*[[Mycophenolate mofetil (CellCept)]]
 
*[[Mycophenolate mofetil (CellCept)]]
  
 
==N==
 
==N==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Nabilone (Cesamet)]]
 
*[[Nabilone (Cesamet)]]
 
*[[Netupitant and palonosetron (Akynzeo)]]
 
*[[Netupitant and palonosetron (Akynzeo)]]
 +
*[[Nonacog beta pegol (Refixia)]]
  
 
==O==
 
==O==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Olanzapine (Zyprexa)]]
 
*[[Olanzapine (Zyprexa)]]
 
*[[Omeprazole (Prilosec)]]
 
*[[Omeprazole (Prilosec)]]
 +
*[[Omidubicel (Omisirge)]] '''FDA approved 2023-04-17'''
 
*[[Ondansetron (Zofran)]]
 
*[[Ondansetron (Zofran)]]
 
*[[Oprelvekin (Neumega)]]
 
*[[Oprelvekin (Neumega)]]
  
 
==P==
 
==P==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Palifermin (Kepivance)]]
 
*[[Palifermin (Kepivance)]]
Line 875: Line 998:
 
*[[Pantoprazole (Protonix)]]
 
*[[Pantoprazole (Protonix)]]
 
*[[Pegfilgrastim (Neulasta)]]
 
*[[Pegfilgrastim (Neulasta)]]
 +
**[[Pegfilgrastim-apgf (Nyvepria)]]
 
**[[Pegfilgrastim-bmez (Ziextenzo)]]
 
**[[Pegfilgrastim-bmez (Ziextenzo)]]
 
**[[Pegfilgrastim-cbqv (Udenyca)]]
 
**[[Pegfilgrastim-cbqv (Udenyca)]]
 +
**[[Pegfilgrastim-fpgk (Stimufend)]]
 
**[[Pegfilgrastim-jmdb (Fulphila)]]
 
**[[Pegfilgrastim-jmdb (Fulphila)]]
 +
**[[Pegfilgrastim-cegf (Cegfila)]]
 +
**[[Pegfilgrastim-gras (Grasustek)]]
 +
**[[Pegfilgrastim-pbbk (Fylnetra)]]
 +
**[[Pegfilgrastim-pelg (Pelgraz)]]
 +
**[[Pegfilgrastim-pelm (Pelmeg)]]
 +
**[[Pegfilgrastim-stim (Stimufend)]]
 
*[[Penicillin V]]
 
*[[Penicillin V]]
 
*[[Pentamidine (Nebupent)]]
 
*[[Pentamidine (Nebupent)]]
Line 888: Line 1,019:
 
*[[Promethazine (Phenergan)]]
 
*[[Promethazine (Phenergan)]]
 
*[[Protamine sulfate]]
 
*[[Protamine sulfate]]
 +
*[[Protein C, human (Ceprotin)]]
 
*[[Prothrombin Complex Concentrate, human]]
 
*[[Prothrombin Complex Concentrate, human]]
  
Line 895: Line 1,027:
  
 
==R==
 
==R==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
−
 
 
*[[Rabeprazole (Aciphex)]]
 
*[[Rabeprazole (Aciphex)]]
 
*[[Raloxifene (Evista)]]
 
*[[Raloxifene (Evista)]]
Line 905: Line 1,032:
 
*[[Ranitidine (Zantac)]]
 
*[[Ranitidine (Zantac)]]
 
*[[Rasburicase (Elitek)]]
 
*[[Rasburicase (Elitek)]]
 +
*[[Remestemcel-L (Prochymal)]]
 
*[[Rho(D) immune globulin (RhoGAM)]]
 
*[[Rho(D) immune globulin (RhoGAM)]]
 +
*[[Rilzabrutinib (PRN-1008)]]
 
*[[Risedronate (Actonel)]]
 
*[[Risedronate (Actonel)]]
 
*[[Rivaroxaban (Xarelto)]]
 
*[[Rivaroxaban (Xarelto)]]
 
*[[Rolapitant (Varubi)]]
 
*[[Rolapitant (Varubi)]]
 
*[[Romiplostim (Nplate)]]
 
*[[Romiplostim (Nplate)]]
 +
*[[Rusfertide (PTG-300)]]
  
 
==S==
 
==S==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Sargramostim (Leukine)]]
 
*[[Sargramostim (Leukine)]]
 
*[[Scopolamine (Scopoderm)]]
 
*[[Scopolamine (Scopoderm)]]
Line 921: Line 1,048:
 
*[[Siltuximab (Sylvant)]]
 
*[[Siltuximab (Sylvant)]]
 
*[[Sirolimus (Rapamune)]]
 
*[[Sirolimus (Rapamune)]]
 +
*[[Sodium thiosulfate (Pedmark)]]
 +
*[[Sutimlimab (Enjaymo)]]
  
 
==T==
 
==T==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Tacrolimus (Prograf)]]
 
*[[Tacrolimus (Prograf)]]
 
*[[Tbo-filgrastim (Granix)]]
 
*[[Tbo-filgrastim (Granix)]]
 +
*[[Telotristat (Xermelo)]]
 
*[[Ticagrelor (Brilinta)]]
 
*[[Ticagrelor (Brilinta)]]
−
*[[Ticlodipine (Ticlid)]]
+
*[[Ticlopidine (Ticlid)]]
 
*[[Tinzaparin (Innohep)]]
 
*[[Tinzaparin (Innohep)]]
 
*[[Tirofiban (Aggrastat)]]
 
*[[Tirofiban (Aggrastat)]]
 
*[[Tocilizumab (Actemra)]]
 
*[[Tocilizumab (Actemra)]]
 +
**[[Tocilizumab-aazg (Tyenne)]]
 +
**[[Tocilizumab-bavi (Tofidence)]]
 
*[[Tofacitinib (Xeljanz)]]
 
*[[Tofacitinib (Xeljanz)]]
 
*[[Tranexamic acid (Cyklokapron)]]
 
*[[Tranexamic acid (Cyklokapron)]]
 +
*[[Trilaciclib (Cosela)]]
 
*[[Trimethoprim-Sulfamethoxazole (Bactrim DS)]]
 
*[[Trimethoprim-Sulfamethoxazole (Bactrim DS)]]
 
*[[Tropisetron (Navoban)]]
 
*[[Tropisetron (Navoban)]]
Line 944: Line 1,074:
  
 
==V==
 
==V==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
*[[Valacyclovir (Valtrex)]]
 
*[[Valacyclovir (Valtrex)]]
 
*[[Valganciclovir (Valcyte)]]
 
*[[Valganciclovir (Valcyte)]]
 +
*[[Valoctocogene roxaparvovec (AAV5-hFVIII-SQ)]]
 
*[[Valproate (Depakote)]]
 
*[[Valproate (Depakote)]]
 +
*[[Verbrinacogene setparvovec (FLT-180a)]]
 
*[[von Willebrand factor and factor VIII complex, human]]
 
*[[von Willebrand factor and factor VIII complex, human]]
 
*[[von Willebrand factor, recombinant]]
 
*[[von Willebrand factor, recombinant]]
 +
*[[Vonoprazan (Takecab)]]
 
*[[Vorapaxar (Zontivity)]]
 
*[[Vorapaxar (Zontivity)]]
 
*[[Voriconazole (Vfend)]]
 
*[[Voriconazole (Vfend)]]
  
 
==W==
 
==W==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Warfarin (Coumadin)]]
 
*[[Warfarin (Coumadin)]]
Line 968: Line 1,095:
  
 
=By Category=
 
=By Category=
−
''Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is still in process so not all of these links are active).''
+
''Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is an ongoing process so not all of these links are active or current).''
  
 
==[[:Category:REMS_program|Drugs in a REMS program]]==
 
==[[:Category:REMS_program|Drugs in a REMS program]]==
  
 
==Cytotoxic Chemotherapy==
 
==Cytotoxic Chemotherapy==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Alkylating agents|Alkylating agents]]
 
*[[:Category:Alkylating agents|Alkylating agents]]
Line 992: Line 1,116:
  
 
==[[:Category:Kinase inhibitors|Kinase inhibitors]]==
 
==[[:Category:Kinase inhibitors|Kinase inhibitors]]==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
<div style="column-count:2;-moz-column-count:2;-webkit-column-count:2">
 
<div style="column-count:2;-moz-column-count:2;-webkit-column-count:2">
 
*[[:Category:AKT1 inhibitors|AKT1 inhibitors]]
 
*[[:Category:AKT1 inhibitors|AKT1 inhibitors]]
Line 1,029: Line 1,150:
  
 
==[[:Category:Endocrine therapeutic|Endocrine therapy]]==
 
==[[:Category:Endocrine therapeutic|Endocrine therapy]]==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Antiandrogens|Antiandrogens]]
 
*[[:Category:Antiandrogens|Antiandrogens]]
Line 1,051: Line 1,169:
  
 
==Biologics==
 
==Biologics==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Antibody medications|Antibody medications]]
 
*[[:Category:Antibody medications|Antibody medications]]
Line 1,065: Line 1,180:
  
 
==Supportive Medications==
 
==Supportive Medications==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Antibacterials|Antibacterials]]
 
*[[:Category:Antibacterials|Antibacterials]]
Line 1,088: Line 1,200:
  
 
==[[:Category:Hematology medications|Benign Hematology Medications]]==
 
==[[:Category:Hematology medications|Benign Hematology Medications]]==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Anticoagulants|Anticoagulants]]
 
*[[:Category:Anticoagulants|Anticoagulants]]
Line 1,110: Line 1,219:
  
 
==[[:Category:Hematopoietic growth factors|Hematopoietic Growth Factors]]==
 
==[[:Category:Hematopoietic growth factors|Hematopoietic Growth Factors]]==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Erythrocyte growth factors|Erythrocyte growth factors]]
 
*[[:Category:Erythrocyte growth factors|Erythrocyte growth factors]]
Line 1,120: Line 1,226:
  
 
==Miscellaneous==
 
==Miscellaneous==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:REMS_program|Drugs in a REMS program]]
 
*[[:Category:REMS_program|Drugs in a REMS program]]
Line 1,132: Line 1,235:
  
 
==Medications by Condition==
 
==Medications by Condition==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 
*[[:Category:B-cell acute lymphoblastic leukemia medications|Acute lymphocytic leukemia medications]]
 
*[[:Category:B-cell acute lymphoblastic leukemia medications|Acute lymphocytic leukemia medications]]
Line 1,142: Line 1,242:
 
*[[:Category:Anal cancer medications|Anal cancer medications]]
 
*[[:Category:Anal cancer medications|Anal cancer medications]]
 
*[[:Category:Anaplastic large cell lymphoma medications|Anaplastic large cell lymphoma medications]]
 
*[[:Category:Anaplastic large cell lymphoma medications|Anaplastic large cell lymphoma medications]]
−
*[[:Category:Basal cell and squamous cell skin cancer medications|Basal cell and squamous cell skin cancer medications]]
 
 
*[[:Category:Bladder cancer medications|Bladder cancer medications]]
 
*[[:Category:Bladder cancer medications|Bladder cancer medications]]
 
*[[:Category:Bone cancer medications |Bone cancer medications]]
 
*[[:Category:Bone cancer medications |Bone cancer medications]]
Line 1,148: Line 1,247:
 
*[[:Category:Burkitt lymphoma medications|Burkitt lymphoma medications]]
 
*[[:Category:Burkitt lymphoma medications|Burkitt lymphoma medications]]
 
*[[:Category:Cancer of unknown primary medications |Cancer of unknown primary medications]]
 
*[[:Category:Cancer of unknown primary medications |Cancer of unknown primary medications]]
−
*[[:Category:Castleman’s disease medications|Castleman’s disease medications]]
+
*[[:Category:Castleman disease medications|Castleman disease medications]]
 
*[[:Category:Central nervous system (CNS) cancer medications|Central nervous system (CNS) cancer medications]]
 
*[[:Category:Central nervous system (CNS) cancer medications|Central nervous system (CNS) cancer medications]]
 
*[[:Category:CNS lymphoma medications|Central nervous system (CNS) lymphoma medications]]
 
*[[:Category:CNS lymphoma medications|Central nervous system (CNS) lymphoma medications]]
 
*[[:Category:Cervical cancer medications|Cervical cancer medications]]
 
*[[:Category:Cervical cancer medications|Cervical cancer medications]]
 
*[[:Category:Chronic lymphocytic leukemia medications|Chronic lymphocytic leukemia (CLL/SLL) medications]]
 
*[[:Category:Chronic lymphocytic leukemia medications|Chronic lymphocytic leukemia (CLL/SLL) medications]]
−
*[[:Category:Chronic myelogenous leukemia medications|Chronic myelogenous leukemia medications]]
+
*[[:Category:Chronic myeloid leukemia medications|Chronic myeloid leukemia (CML) medications]]
−
*[[:Category:Chronic myelomonocytic leukemia medications|Chronic myelomonocytic leukemia medications]]
+
*[[:Category:Chronic myelomonocytic leukemia medications|Chronic myelomonocytic leukemia (CMML) medications]]
 
*[[:Category:Colon cancer medications|Colon cancer medications]]
 
*[[:Category:Colon cancer medications|Colon cancer medications]]
 +
*[[:Category:Colorectal cancer medications|Colorectal cancer (CRC) medications]]
 +
*[[:Category:Cutaneous basal cell carcinoma medications|Cutaneous BCC medications]]
 +
*[[:Category:Cutaneous squamous cell carcinoma medications|Cutaneous SCC medications]]
 
*[[:Category:Cutaneous T-cell lymphoma medications|Cutaneous T-cell lymphoma medications]]
 
*[[:Category:Cutaneous T-cell lymphoma medications|Cutaneous T-cell lymphoma medications]]
 
*[[:Category:Diffuse large B-cell lymphoma medications|Diffuse large B-cell lymphoma medications]]
 
*[[:Category:Diffuse large B-cell lymphoma medications|Diffuse large B-cell lymphoma medications]]
Line 1,207: Line 1,309:
  
 
==[[:Category:Routed medications|Medications by Route of Administration]]==
 
==[[:Category:Routed medications|Medications by Route of Administration]]==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[:Category:Intra-arterial medications|Intraarterial (IA) medications]]
 
*[[:Category:Intra-arterial medications|Intraarterial (IA) medications]]
Line 1,221: Line 1,320:
 
*[[:Category:Subcutaneous medications|Subcutaneous (SC) medications]]
 
*[[:Category:Subcutaneous medications|Subcutaneous (SC) medications]]
  
−
==Medications by Year of Approval==
+
==Medications by FDA Year of Approval==
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
 
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 
*[[:Category:FDA approved in 1939|FDA approved in 1939]]
 
*[[:Category:FDA approved in 1939|FDA approved in 1939]]
Line 1,297: Line 1,393:
 
*[[:Category:FDA approved in 2018|FDA approved in 2018]]
 
*[[:Category:FDA approved in 2018|FDA approved in 2018]]
 
*[[:Category:FDA approved in 2019|FDA approved in 2019]]
 
*[[:Category:FDA approved in 2019|FDA approved in 2019]]
 +
*[[:Category:FDA approved in 2020|FDA approved in 2020]]
 +
*[[:Category:FDA approved in 2021|FDA approved in 2021]]
 +
*[[:Category:FDA approved in 2022|FDA approved in 2022]]
 +
*[[:Category:FDA approved in 2023|FDA approved in 2023]]
 +
*[[:Category:FDA approved in 2024|FDA approved in 2024]]
 
</div>
 
</div>
  
 
=Interesting and Helpful Links=
 
=Interesting and Helpful Links=
−
{| class="wikitable" style="float:right; margin-left: 5px;"
+
 
−
|-
 
−
|[[#top|back to top]]
 
−
|}
 
  
 
*[[Antidepressants and other psychiatric medications in cancer care]]
 
*[[Antidepressants and other psychiatric medications in cancer care]]
 
*[[Antiemesis|Antiemetic support]]
 
*[[Antiemesis|Antiemetic support]]
 
*[https://doi.org/10.1200/JCO.2012.45.8661 Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology Clinical Practice Guideline (2013)]
 
*[https://doi.org/10.1200/JCO.2012.45.8661 Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology Clinical Practice Guideline (2013)]
−
*[https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology]
+
*[https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society (ASCO/ONS) Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology]
 
*[http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p Chemotherapy Administration Sequence]<ref>Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. [http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p link to original article]</ref> - with chemotherapy sequencing chart
 
*[http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p Chemotherapy Administration Sequence]<ref>Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. [http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p link to original article]</ref> - with chemotherapy sequencing chart
−
*[https://onlinelibrary.wiley.com/doi/10.1111/j.1743-7563.2010.01321.x/full The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy.] [https://pubmed.ncbi.nlm.nih.gov/20887505 PubMed]
+
*[https://doi.org/10.1111/j.1743-7563.2010.01321.x The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy.] [https://pubmed.ncbi.nlm.nih.gov/20887505/ PubMed]
 
*[https://crediblemeds.org/ CredibleMeds.org] - lists of QT-prolonging drugs; requires free registration to see full list
 
*[https://crediblemeds.org/ CredibleMeds.org] - lists of QT-prolonging drugs; requires free registration to see full list
 
*[http://www.accessdata.fda.gov/scripts/drugshortages/default.cfm FDA drug shortages list]
 
*[http://www.accessdata.fda.gov/scripts/drugshortages/default.cfm FDA drug shortages list]
Line 1,316: Line 1,414:
 
*[http://dailymed.nlm.nih.gov/dailymed/index.cfm DailyMed] - a comprehensive NLM portal to all FDA-approved drugs
 
*[http://dailymed.nlm.nih.gov/dailymed/index.cfm DailyMed] - a comprehensive NLM portal to all FDA-approved drugs
 
*[http://www.accessdata.fda.gov/scripts/cder/drugsatfda/ Drugs@FDA] - the main portal into the FDA drug database
 
*[http://www.accessdata.fda.gov/scripts/cder/drugsatfda/ Drugs@FDA] - the main portal into the FDA drug database
−
*[http://www.cancer.gov/drugdictionary The NCI Drug Dictionary] - an extensive resource with most antineoplastics (approved and in clinical trials) listed
+
*[https://www.cancer.gov/drugdictionary The NCI Drug Dictionary] - an extensive resource with most antineoplastics (approved and in clinical trials) listed
 
*[http://blogs.sciencemag.org/pipeline/ In the Pipeline] - a blog from a veteran of the pharmaceutical industry, Derek Lowe. General but much is cancer-relevant. The [http://www.pipeline.corante.com/ old home] of this blog is no longer active.
 
*[http://blogs.sciencemag.org/pipeline/ In the Pipeline] - a blog from a veteran of the pharmaceutical industry, Derek Lowe. General but much is cancer-relevant. The [http://www.pipeline.corante.com/ old home] of this blog is no longer active.
 
*[[Steroid conversions]]
 
*[[Steroid conversions]]

Latest revision as of 20:19, 27 June 2024

Back to Top

Guidelines

Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any guideline published 5+ years ago to be for historical purposes, only.

Other interesting and helpful links can be found by clicking the link.

Chemotherapy safety standards

Dose adjustments

Antimicrobials

Growth factors

Approved antineoplastics

This section contains anticancer drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound. For drugs first approved within the current or prior calendar years, the date of initial approval is also provided here.

A

B

C

D

E

F

G

H

I

K

L

M

N

O

P

Q

R

S

T

U

V

Z

Discontinued antineoplastics

This section contains drugs that have had at least one formal approval in any domain (FDA, EMA, etc), but are no longer on the market. Note that it is possible that these drugs continue to be available in some limited way, such as through compassionate use programs.

A

D

E

F

L

M

O

P

S

T

U

V

Investigational antineoplastics

This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.

A

B

C

D

E

F

G

H

I

J

L

M

N

O

P

Q

R

S

T

U

V

Z

Supportive and other medications

This section contains supportive drugs that are either approved or investigational. Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound.

A

B

C

D

E

F

G

H

I

L

M

N

O

P

Q

R

S

T

U

V

W

Z

By Category

Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is an ongoing process so not all of these links are active or current).

Drugs in a REMS program

Cytotoxic Chemotherapy

Kinase inhibitors

Endocrine therapy

Investigational and Discontinued

Biologics

Supportive Medications

Radioactive agents

Benign Hematology Medications

Hematopoietic Growth Factors

Miscellaneous

Medications by Condition

Medications by Route of Administration

Medications by FDA Year of Approval

Interesting and Helpful Links

References

  1. ↑ Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. link to original article PubMed
  2. ↑ Smith TJ, Bohlke K, Lyman GH, Carson KR, Crawford J, Cross SJ, Goldberg JM, Khatcheressian JL, Leighl NB, Perkins CL, Somlo G, Wade JL, Wozniak AJ, Armitage JO. Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015 Oct 1;33(28):3199-212. Epub 2015 Jul 13. link to original article PubMed
  3. ↑ Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. link to original article
Retrieved from "https://hemonc.org/w/index.php?title=Drug_index&oldid=87096"