Difference between revisions of "Drug index"

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*[[List of chemotherapy regimens]]
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*[[Vesicant & irritant chemotherapy]]
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*[[Antiemesis|Antiemetic support]]
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[[#top|Back to Top]]
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*[[Steroid conversions]]
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</div>
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*[http://dryang.org/bi/forms/ptinfo Third party patient information sheets (password protected)]
+
=Guidelines=
 +
'''Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any guideline published 5+ years ago to be for historical purposes, only.'''
 +
 
 +
'''Other [[#Interesting_and_Helpful_Links|interesting and helpful links]] can be found by clicking the link.'''
 +
==Chemotherapy safety standards==
 +
 
 +
*'''2020:''' Dillmon et al. [https://doi.org/10.1200/JCO.19.02297 Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards] [https://pubmed.ncbi.nlm.nih.gov/31815576/ PubMed]
 +
*'''2019:''' Celano et al. [https://doi.org/10.1200/JCO.18.01616 Safe handling of hazardous drugs: ASCO standards] [https://pubmed.ncbi.nlm.nih.gov/30620670/ PubMed]
 +
*'''2016:''' Neuss et al. [https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society chemotherapy administration safety standards, including standards for pediatric oncology]
 +
*'''2010:''' Carrington et al. [https://doi.org/10.1111/j.1743-7563.2010.01321.x The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy] [https://pubmed.ncbi.nlm.nih.gov/20887505/ PubMed]
 +
 
 +
==Dose adjustments==
 +
*'''2021:''' Griggs et al. [https://doi.org/10.1200/jco.21.00471 Appropriate Systemic Therapy Dosing for Obese Adult Patients With Cancer: ASCO Guideline Update]
 +
 
 +
*'''2012:''' Griggs et al. [https://doi.org/10.1200/jco.2011.39.9436 Appropriate chemotherapy dosing for obese adult patients with cancer: American Society of Clinical Oncology Clinical Practice Guideline]<ref>Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. [https://doi.org/10.1200/jco.2011.39.9436 link to original article] [https://pubmed.ncbi.nlm.nih.gov/22473167/ PubMed]</ref>
 +
 
 +
==Antimicrobials==
 +
 
 +
*'''2013:''' [https://doi.org/10.1200/JCO.2012.45.8661 Antimicrobial prophylaxis and outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology Clinical Practice Guideline]
 +
 
 +
==Growth factors==
 +
 
 +
*'''2015:''' [https://doi.org/10.1200/jco.2015.62.3488 Update of ASCO Clinical Practice Guideline recommendations for the use of WBC growth factors]<ref>Smith TJ, Bohlke K, Lyman GH, Carson KR, Crawford J, Cross SJ, Goldberg JM, Khatcheressian JL, Leighl NB, Perkins CL, Somlo G, Wade JL, Wozniak AJ, Armitage JO. Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015 Oct 1;33(28):3199-212. Epub 2015 Jul 13. [https://doi.org/10.1200/jco.2015.62.3488 link to original article] [https://pubmed.ncbi.nlm.nih.gov/26169616/ PubMed]</ref>
 +
 
 +
=Approved antineoplastics=
 +
''This section contains anticancer drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound. For drugs first approved within the current or prior calendar years, the date of initial approval is also provided here.''
 
==A==
 
==A==
 +
 +
*[[Abarelix (Plenaxis)]]
 +
*[[Abemaciclib (Verzenio)]]
 +
*[[Abiraterone (Zytiga)]]
 +
*[[Acalabrutinib (Calquence)]]
 +
*[[Aclarubicin (Aclacinomycin)]]
 +
*[[Adagrasib (Krazati)]]
 +
*[[Afatinib (Gilotrif)]]
 
*[[Aldesleukin (Proleukin)]]
 
*[[Aldesleukin (Proleukin)]]
 +
*[[Alectinib (Alecensa)]]
 
*[[Alemtuzumab (Campath)]]
 
*[[Alemtuzumab (Campath)]]
 +
*[[Alitretinoin (Panretin)]]
 +
*[[All-trans retinoic acid (ATRA)]]
 +
*[[Alpelisib (Piqray)]]
 
*[[Altretamine (Hexalen)]]
 
*[[Altretamine (Hexalen)]]
 +
*[[Alvocidib (Flavopiridol)]]
 +
*[[Amifostine (Ethyol)]]
 
*[[Aminoglutethimide (Cytadren)]]
 
*[[Aminoglutethimide (Cytadren)]]
 +
*[[Amivantamab (Rybrevant)]]
 +
*[[Amrubicin (Calsed)]]
 
*[[Amsacrine (Amsidine)]]
 
*[[Amsacrine (Amsidine)]]
−
*[[Anagrelide (Agrylin)]]
+
*[[Anastrozole (Arimidex)]]
−
*[[Anastrozole (Arimidex)]]  
+
*[[Ancestim (Stemgen)]]
 +
*[[Anlotinib (Fukewei)]]
 +
*[[Apalutamide (Erleada)]]
 +
*[[Apatinib (Aitan)]]
 
*[[Arsenic trioxide (Trisenox)]]
 
*[[Arsenic trioxide (Trisenox)]]
−
*[[Asparaginase (Elspar)]]
+
*[[Asciminib (Scemblix)]]
−
*[[Atovaquone (Mepron)]]
+
*[[Asparaginase Erwinia chrysanthemi (Erwinaze)]]
 +
**[[Asparaginase erwinia chrysanthemi-rywn (Rylaze)]]
 +
*[[Atezolizumab (Tecentriq)]]
 +
*[[Aumolertinib (Amelie)]]
 +
*[[Avapritinib (Ayvakit)]]
 +
*[[Avelumab (Bavencio)]]
 +
*[[Axicabtagene ciloleucel (Yescarta)]]
 +
*[[Axitinib (Inlyta)]]
 +
*[[Azacitidine (Onureg)]]
 
*[[Azacitidine (Vidaza)]]
 
*[[Azacitidine (Vidaza)]]
  
 
==B==
 
==B==
−
*[[Bacillus Calmette-Guerin (BCG, TheraCys)]]
+
 
−
*[[Bendamustine (Treanda)]]
+
 
 +
*[[BCG vaccine]]
 +
*[[Belantamab mafodotin (Blenrep)]]
 +
*[[Belinostat (Beleodaq)]]
 +
*[[Belotecan (Camptobell)]]
 +
*[[Belumosudil (Rezurock)]]
 +
*[[Belzutifan (Welireg)]]
 +
*[[Bendamustine]]
 +
*[[Benralizumab (Fasenra)]]
 
*[[Bevacizumab (Avastin)]]
 
*[[Bevacizumab (Avastin)]]
 +
**[[Bevacizumab-adcd (Vegzelga)]]
 +
**[[Bevacizumab-aveg (Avegra)]]
 +
**[[Bevacizumab-awwb (Mvasi)]]
 +
**[[Bevacizumab-aybi (Aybintio)]]
 +
**[[Bevacizumab-bvzr (Zirabev)]]
 +
**[[Bevacizumab-equi (Equidacent)]]
 +
**[[Bevacizumab-maly (Alymsys)]]
 +
**[[Bevacizumab-onbe (Onbevzi)]]
 +
**[[Bevacizumab-tnjn (Avzivi)]] '''FDA approved 2023-12'''
 
*[[Bexarotene (Targretin)]]
 
*[[Bexarotene (Targretin)]]
 
*[[Bicalutamide (Casodex)]]
 
*[[Bicalutamide (Casodex)]]
 +
*[[Binimetinib (Mektovi)]]
 
*[[Bleomycin (Blenoxane)]]
 
*[[Bleomycin (Blenoxane)]]
 +
*[[Blinatumomab (Blincyto)]]
 +
*[[Borofalan-10B (Steboronine)]]
 
*[[Bortezomib (Velcade)]]
 
*[[Bortezomib (Velcade)]]
 +
*[[Bosutinib (Bosulif)]]
 +
*[[Brentuximab vedotin (Adcetris)]]
 +
*[[Brexucabtagene autoleucel (Tecartus)]]
 +
*[[Brigatinib (Alunbrig)]]
 +
*[[Buserelin (Suprefact)]]
 
*[[Busulfan (Myleran)]]
 
*[[Busulfan (Myleran)]]
  
 
==C==
 
==C==
 +
 +
 
*[[Cabazitaxel (Jevtana)]]
 
*[[Cabazitaxel (Jevtana)]]
−
*[[Cabozantinib]] '''in clinical trial'''
+
*[[Cabozantinib (Cabometyx)]]
 +
*[[Cabozantinib (Cometriq)]]
 +
*[[Calaspargase (Asparlas)]]
 +
*[[Camrelizumab (AiRuiKa)]]
 
*[[Capecitabine (Xeloda)]]
 
*[[Capecitabine (Xeloda)]]
 +
*[[Capivasertib (Truqap)]] '''FDA approved 2023-11-16'''
 +
*[[Caplacizumab (Cablivi)]]
 +
*[[Capmatinib (Tabrecta)]]
 
*[[Carboplatin (Paraplatin)]]
 
*[[Carboplatin (Paraplatin)]]
−
*[[Carmustine (BiCNU)]]
+
*[[Carfilzomib (Kyprolis)]]
 +
*[[Carmofur (HCFU)]]
 +
*[[Carmustine (BCNU)]]
 +
*[[Carmustine wafer, polifeprosan 20 (Gliadel)]]
 +
*[[Cemiplimab (Libtayo)]]
 +
*[[Ceritinib (Zykadia)]]
 
*[[Cetuximab (Erbitux)]]
 
*[[Cetuximab (Erbitux)]]
 +
*[[Chidamide (Epidaza)]]
 
*[[Chlorambucil (Leukeran)]]
 
*[[Chlorambucil (Leukeran)]]
 +
*[[Chlorozotocin (DCNU)]]
 +
*[[Ciltacabtagene autoleucel (Carvykti)]]
 
*[[Cisplatin (Platinol)]]
 
*[[Cisplatin (Platinol)]]
 
*[[Cladribine (Leustatin)]]
 
*[[Cladribine (Leustatin)]]
 
*[[Clofarabine (Clolar)]]
 
*[[Clofarabine (Clolar)]]
 +
*[[Cobimetinib (Cotellic)]]
 +
*[[Copanlisib (Aliqopa)]]
 +
*[[Cortisone]]
 
*[[Crizotinib (Xalkori)]]
 
*[[Crizotinib (Xalkori)]]
 
*[[Cyclophosphamide (Cytoxan)]]
 
*[[Cyclophosphamide (Cytoxan)]]
−
*[[Cytarabine (Cytosar)]]
+
*[[Cyproterone acetate (Androcur)]]
 +
*[[Cytarabine (Ara-C)]]
 +
*[[Cytarabine and daunorubicin liposomal (Vyxeos)]]
 
*[[Cytarabine liposomal (DepoCyt)]]
 
*[[Cytarabine liposomal (DepoCyt)]]
  
 
==D==
 
==D==
 +
 +
 +
*[[Dabrafenib (Tafinlar)]]
 
*[[Dacarbazine (DTIC)]]
 
*[[Dacarbazine (DTIC)]]
 +
*[[Dacomitinib (Vizimpro)]]
 
*[[Dactinomycin (Cosmegen)]]
 
*[[Dactinomycin (Cosmegen)]]
 +
*[[Daratumumab (Darzalex)]]
 +
*[[Daratumumab and hyaluronidase (Darzalex Faspro)]]
 +
*[[Daratumumab and vorhyaluronidase (Darzquro)]]
 +
*[[Darinaparsin (Darvias)]]
 +
*[[Darolutamide (Nubeqa)]]
 
*[[Dasatinib (Sprycel)]]
 
*[[Dasatinib (Sprycel)]]
 
*[[Daunorubicin (Cerubidine)]]
 
*[[Daunorubicin (Cerubidine)]]
−
*[[Daunorubicin liposomal (DaunoXome)]]
 
 
*[[Decitabine (Dacogen)]]
 
*[[Decitabine (Dacogen)]]
 +
*[[Decitabine and cedazuridine (Inqovi)]]
 
*[[Degarelix (Firmagon)]]
 
*[[Degarelix (Firmagon)]]
−
*[[Denileukin diftitox (Ontak)]]
+
*[[Dexamethasone (Decadron)]]
 +
*[[Dinutuximab (Unituxin)]]
 +
*[[Dinutuximab beta (Qarziba)]]
 
*[[Docetaxel (Taxotere)]]
 
*[[Docetaxel (Taxotere)]]
 +
*[[Donafenib (Zepsun)]]
 +
*[[Dostarlimab (Jemperli)]]
 +
*[[Doxifluridine (Didox)]]
 
*[[Doxorubicin (Adriamycin)]]
 
*[[Doxorubicin (Adriamycin)]]
−
*[[Doxorubicin liposomal (Doxil)]]
+
*[[Durvalumab (Imfinzi)]]
 
*[[Dutasteride (Avodart)]]
 
*[[Dutasteride (Avodart)]]
 +
*[[Duvelisib (Copiktra)]]
  
 
==E==
 
==E==
 +
*[[Eflornithine (Iwilfin)]] '''FDA approved 2023-12-13'''
 +
*[[Elacestrant (Orserdu)]] '''FDA approved 2023-01-27'''
 +
*[[Elotuzumab (Empliciti)]]
 +
*[[Elranatamab (Elrexfio)]] '''FDA approved on 2023-08-14'''
 +
*[[Emapalumab (Gamifant)]]
 +
*[[Enasidenib (Idhifa)]]
 +
*[[Encorafenib (Braftovi)]]
 +
*[[Enfortumab vedotin (Padcev)]]
 +
*[[Ensartinib (Ensacove)]]
 +
*[[Entrectinib (Rozlytrek)]]
 +
*[[Envafolimab (Enweida)]]
 +
*[[Enzalutamide (Xtandi)]]
 +
*[[Epcoritamab (Epkinly)]] '''FDA approved 2023-05-19'''
 
*[[Epirubicin (Ellence)]]
 
*[[Epirubicin (Ellence)]]
 +
*[[Erdafitinib (Balversa)]]
 
*[[Eribulin (Halaven)]]
 
*[[Eribulin (Halaven)]]
 
*[[Erlotinib (Tarceva)]]
 
*[[Erlotinib (Tarceva)]]
 +
*[[Estradiol]]
 
*[[Estramustine (Emcyt)]]
 
*[[Estramustine (Emcyt)]]
 
*[[Etoposide (Vepesid)]]
 
*[[Etoposide (Vepesid)]]
 
*[[Everolimus (Afinitor)]]
 
*[[Everolimus (Afinitor)]]
−
*[[Estramustine (Emcyt)]]
 
 
*[[Exemestane (Aromasin)]]
 
*[[Exemestane (Aromasin)]]
  
 
==F==
 
==F==
−
*[[Filgrastim (Neupogen)]]
+
*[[Fadrozole (Afema)]]
−
*[[Finasteride (Proscar)]]
+
*[[Fedratinib (Inrebic)]]
 
*[[Fluorouracil (5-FU)]]
 
*[[Fluorouracil (5-FU)]]
−
*[[Floxuridine (FDUR)]]
 
 
*[[Fludarabine (Fludara)]]
 
*[[Fludarabine (Fludara)]]
 +
*[[Flumatinib (Xinfu)]]
 
*[[Flutamide (Eulexin)]]
 
*[[Flutamide (Eulexin)]]
−
*[[Folinic acid (Leucovorin)]]
+
*[[Leucovorin (Folinic acid)]]
 +
*[[Forodesine (Fodosine)]]
 +
*[[Fostamatinib (Tavalisse)]]
 +
*[[Fotemustine (Muphoran)]]
 +
*[[Fruquintinib (Elunate)]]
 
*[[Fulvestrant (Faslodex)]]
 
*[[Fulvestrant (Faslodex)]]
 +
*[[Furmonertinib (Ivesa)]]
 +
*[[Futibatinib (Lytgobi)]]
  
 
==G==
 
==G==
 +
 +
 +
*[[Gallium Ga 68 gozetotide (Locametz)]]
 
*[[Gefitinib (Iressa)]]
 
*[[Gefitinib (Iressa)]]
 
*[[Gemcitabine (Gemzar)]]
 
*[[Gemcitabine (Gemzar)]]
 +
*[[Gemtuzumab ozogamicin (Mylotarg)]]
 +
*[[Gilteritinib (Xospata)]]
 +
*[[Glasdegib (Daurismo)]]
 +
*[[Glofitamab (Columvi)]] '''FDA approved 2023-06-15'''
 
*[[Goserelin (Zoladex)]]
 
*[[Goserelin (Zoladex)]]
  
 
==H==
 
==H==
−
*[[Hexamethylmelamine (Altretamine)]]
+
*[[Heptaplatin (SunPla)]]
 +
*[[Histamine dihydrochloride (Ceplene)]]
 +
*[[Histrelin (Vantas)]]
 +
*[[Hydrocortisone (Cortef)]]
 
*[[Hydroxyurea (Hydrea)]]
 
*[[Hydroxyurea (Hydrea)]]
  
 
==I==
 
==I==
−
*[[Ibritumomab (Zevalin)]]
+
 
 +
 
 +
*[[Ibritumomab tiuxetan (Zevalin)]]
 +
*[[Ibrutinib (Imbruvica)]]
 +
*[[Icotinib (Conmana)]]
 
*[[Idarubicin (Idamycin)]]
 
*[[Idarubicin (Idamycin)]]
 +
*[[Idecabtagene vicleucel (Abecma)]]
 +
*[[Idelalisib (Zydelig)]]
 
*[[Ifosfamide (Ifex)]]
 
*[[Ifosfamide (Ifex)]]
 
*[[Imatinib (Gleevec)]]
 
*[[Imatinib (Gleevec)]]
−
*[[Ipilimumab (Yervoy)]]
+
*[[Imetelstat (Rytelo)]] '''FDA approved 2024-06-06'''
 +
*[[Infigratinib (Truseltiq)]]
 +
*[[Inotuzumab ozogamicin (Besponsa)]]
 
*[[Interferon alfa-2a (Roferon-A)]]
 
*[[Interferon alfa-2a (Roferon-A)]]
 
*[[Interferon alfa-2b (Intron-A)]]
 
*[[Interferon alfa-2b (Intron-A)]]
 +
*[[Interferon gamma-1a (Imunomax-γ)]]
 +
*[[Interferon gamma-1b (Actimmune)]]
 +
*[[Iobenguane I 131 (Azedra)]]
 +
*[[Iodine-131]]
 +
*[[Ipilimumab (Yervoy)]]
 
*[[Irinotecan (Camptosar)]]
 
*[[Irinotecan (Camptosar)]]
 +
*[[Irinotecan liposome (Onivyde)]]
 +
*[[Isatuximab (Sarclisa)]]
 +
*[[Isotretinoin (Accutane)]]
 +
*[[Ivosidenib (Tibsovo)]]
 
*[[Ixabepilone (Ixempra)]]
 
*[[Ixabepilone (Ixempra)]]
 +
*[[Ixazomib (Ninlaro)]]
 +
 +
==K==
 +
 +
*[[Ketoconazole (Nizoral)]]
  
 
==L==
 
==L==
 +
 +
*[[Lanreotide (Somatuline)]]
 +
*[[Lanreotide LAR (Somatuline Depot)]]
 
*[[Lapatinib (Tykerb)]]
 
*[[Lapatinib (Tykerb)]]
 +
*[[Larotrectinib (Vitrakvi)]]
 +
*[[Lasofoxifene (Fablyn)]]
 
*[[Lenalidomide (Revlimid)]]
 
*[[Lenalidomide (Revlimid)]]
 +
*[[Lenvatinib (Lenvima)]]
 
*[[Letrozole (Femara)]]
 
*[[Letrozole (Femara)]]
 
*[[Leuprolide (Lupron)]]
 
*[[Leuprolide (Lupron)]]
−
*[[Lomustine (Ceenu)]]
+
*[[Levoleucovorin (Fusilev)]]
 +
*[[Lifileuecel (Contego)]] '''FDA approved 2024-02-16'''
 +
*[[Lisocabtagene maraleucel (Breyanzi)]]
 +
*[[Lobaplatin (D-19466)]]
 +
*[[Lomustine (CCNU)]]
 +
*[[Loncastuximab tesirine (Zynlonta)]]
 +
*[[Lorlatinib (Lorbrena)]]
 +
*[[Lurbinectedin (Zepzelca)]]
 +
*[[Lutetium Lu 177 dotatate (Lutathera)]]
 +
*[[Lutetium Lu 177 vipivotide tetraxetan (Pluvicto)]]
  
 
==M==
 
==M==
 +
 +
*[[Margetuximab (Margenza)]]
 
*[[Mechlorethamine (Mustargen)]]
 
*[[Mechlorethamine (Mustargen)]]
 +
*[[Medroxyprogesterone acetate (MPA)]]
 +
*[[Megestrol (Megace)]]
 
*[[Melphalan (Alkeran)]]
 
*[[Melphalan (Alkeran)]]
−
*[[Mercaptopurine (Purinethol)]]
+
*[[Melphalan for Injection-Hepatic Delivery System (Hepzato Kit)]] '''FDA approved on 2023-08-14'''
−
*[[Mesna (Mesnex)]]
+
*[[Mepolizumab (Nucala)]]
 +
*[[Mercaptopurine (6-MP)]]
 
*[[Methotrexate (MTX)]]
 
*[[Methotrexate (MTX)]]
 +
*[[Methoxsalen (Uvadex)]]
 +
*[[Methylprednisolone (Solumedrol)]]
 +
*[[Midostaurin (Rydapt)]]
 +
*[[Mifamurtide (Mepact)]]
 +
*[[Miriplatin (Miripla)]]
 +
*[[Mirvetuximab soravtansine (Elahere)]]
 +
*[[Mitomycin pyelocalyceal (Jelmyto)]]
 
*[[Mitomycin (Mutamycin)]]
 
*[[Mitomycin (Mutamycin)]]
 
*[[Mitotane (Lysodren)]]
 
*[[Mitotane (Lysodren)]]
 
*[[Mitoxantrone (Novantrone)]]
 
*[[Mitoxantrone (Novantrone)]]
 +
*[[Mobocertinib (Exkivity)]]
 +
*[[Mogamulizumab (Poteligeo)]]
 +
*[[Momelotinib (Ojjaara)]] '''FDA approved 2023-09-15'''
 +
*[[Mosunetuzumab (Lunsumio)]]
 +
*[[Moxetumomab pasudotox (Lumoxiti)]]
  
 
==N==
 
==N==
−
*[[Nelerabine (Arranon)]]
+
*[[Nadofaragene firadenovec (Adstiladrin)]]
 +
*[[Naxitamab (Danyelza)]]
 +
*[[Necitumumab (Portrazza)]]
 +
*[[Nedaplatin (Aqupla)]]
 +
*[[Nelarabine (Arranon)]]
 +
*[[Neratinib (Nerlynx)]]
 
*[[Nilotinib (Tasigna)]]
 
*[[Nilotinib (Tasigna)]]
 
*[[Nilutamide (Nilandron)]]
 
*[[Nilutamide (Nilandron)]]
 +
*[[Nimotuzumab (Theraloc)]]
 +
*[[Nimustine (ACNU)]]
 +
*[[Nintedanib (Vargatef)]]
 +
*[[Niraparib (Zejula)]]
 +
*[[Niraparib and abiraterone (Akeega)]] '''FDA approved 2023-08-11'''
 +
*[[Nirogacestat (Ogsiveo)]] '''FDA approved 2023-11-27'''
 +
*[[Nivolumab (Opdivo)]]
 +
*[[Nivolumab and relatlimab (Opdualag)]]
 +
*[[Nogapendekin alfa inbakicept (Anktiva)]] '''FDA approved 2024-04-22'''
 +
*[[Non-pegylated liposomal doxorubicin (Myocet)]]
 +
*[[Norethandrolone (Nilevar)]]
 +
*[[NovoTTF-100A system (Optune)]]
  
 
==O==
 
==O==
 +
 +
*[[Obinutuzumab (Gazyva)]]
 
*[[Octreotide (Sandostatin)]]
 
*[[Octreotide (Sandostatin)]]
−
*[[Ofatumumab (Arzzera)]]
+
*[[Octreotide LAR (Sandostatin LAR)]]
 +
*[[Ofatumumab (Arzerra)]]
 +
*[[Olaparib (Lynparza)]]
 +
*[[Olutasidenib (Rezlidhia)]]
 +
*[[Olverembatinib (HQP-1351)]]
 +
*[[Omacetaxine (Synribo)]]
 +
*[[Osimertinib (Tagrisso)]]
 
*[[Oxaliplatin (Eloxatin)]]
 
*[[Oxaliplatin (Eloxatin)]]
  
 
==P==
 
==P==
 +
 +
 
*[[Paclitaxel (Taxol)]]
 
*[[Paclitaxel (Taxol)]]
 
*[[Paclitaxel, nanoparticle albumin-bound (Abraxane)]]
 
*[[Paclitaxel, nanoparticle albumin-bound (Abraxane)]]
 +
*[[Paclitaxel, polymeric micelle-bound (Genexol-PM)]]
 +
*[[Pacritinib (Vonjo)]]
 +
*[[Padeliporfin (Tookad)]]
 +
*[[Palbociclib (Ibrance)]]
 
*[[Panitumumab (Vectibix)]]
 
*[[Panitumumab (Vectibix)]]
−
*[[Peg-asparginase (Oncospar)]]
+
*[[Panobinostat (Farydak)]]
−
*[[Pegfilgrastim (Neulasta)]]
+
*[[Pazopanib (Votrient)]]
 +
*[[Pegaspargase (Oncaspar)]]
 +
*[[Peginterferon alfa-2a (Pegasys)]]
 +
*[[Peginterferon alfa-2b (Sylatron)]]
 +
*[[Pegylated liposomal doxorubicin (Doxil)]]
 +
*[[Pembrolizumab (Keytruda)]]
 
*[[Pemetrexed (Alimta)]]
 
*[[Pemetrexed (Alimta)]]
−
*[[Pentamidine (Nebupent)]]
+
*[[Pemigatinib (Pemazyre)]]
 +
*[[Penpulimab (Anniko)]]
 
*[[Pentostatin (Nipent)]]
 
*[[Pentostatin (Nipent)]]
−
*[[Plicamycin (Mithracin)]]
+
*[[Pertuzumab (Perjeta)]]
 +
*[[Pertuzumab and Trastuzumab hyaluronidase (Phesgo)]]
 +
*[[Pexidartinib (Turalio)]]
 +
*[[Pipobroman (Vercyte)]]
 +
*[[Pirarubicin (THP)]]
 +
*[[Pirtobrutinib (Jaypirca)]] '''FDA approved 2023-01-27'''
 +
*[[Pixantrone (Pixuvri)]]
 +
*[[Polatuzumab vedotin (Polivy)]]
 +
*[[Pomalidomide (Pomalyst)]]
 +
*[[Ponatinib (Iclusig)]]
 
*[[Porfimer (Photofrin)]]
 
*[[Porfimer (Photofrin)]]
 
*[[Pralatrexate (Folotyn)]]
 
*[[Pralatrexate (Folotyn)]]
 +
*[[Pralsetinib (Gavreto)]]
 
*[[Prednisone (Sterapred)]]
 
*[[Prednisone (Sterapred)]]
 +
*[[Prednisolone (Millipred)]]
 
*[[Procarbazine (Matulane)]]
 
*[[Procarbazine (Matulane)]]
 +
*[[Pyrotinib (Irene)]]
 +
 +
==Q==
 +
*[[Quizartinib (Vanflyta)]]
  
 
==R==
 
==R==
−
*[[Raloxifene (Evista)]]
+
*[[Racotumomab (Vaxira)]]
 +
*[[Radium-223 (Xofigo)]]
 +
*[[Radotinib (Supect)]]
 +
*[[Raltitrexed (Tomudex)]]
 +
*[[Ramucirumab (Cyramza)]]
 +
*[[Ranimustine (Cymerin)]]
 +
*[[Ravulizumab (Ultomiris)]]
 +
*[[Realgar-Indigo naturalis formulation]]
 +
*[[Regorafenib (Stivarga)]]
 +
*[[Relugolix (Orgovyx)]]
 +
*[[Repotrectinib (Augtyro)]] '''FDA approved 2023-11-15'''
 +
*[[Retifanlimab (Zynyz)]] '''FDA approved 2023-03-22'''
 +
*[[Ribociclib (Kisqali)]]
 +
*[[Ripretinib (Qinlock)]]
 
*[[Rituximab (Rituxan)]]
 
*[[Rituximab (Rituxan)]]
−
*[[Romidepsin (Isodax)]]
+
**[[Rituximab-abbs (Truxima)]]
−
*[[Romiplostim (Nplate)]]
+
**[[Rituximab-arrx (Riabni)]]
−
*[[Ruxolitinib (Jakafi)]] - '''FDA approved 11/16/2011'''
+
**[[Rituximab-pvvr (Ruxience)]]
 +
**[[Rituximab-blit (Blitzima)]]
 +
**[[Rituximab-rite (Ritemvia)]]
 +
**[[Rituximab-rixa (Rixathon)]]
 +
**[[Rituximab-rixi (Riximyo)]]
 +
*[[Rituximab and hyaluronidase human (Rituxan Hycela)]]
 +
*[[Romidepsin (Istodax)]]
 +
*[[Ropeginterferon alfa-2b (Besremi)]]
 +
*[[Rucaparib (Rubraca)]]
 +
*[[Ruxolitinib (Jakafi)]]
  
 
==S==
 
==S==
−
*[[Sargramostim (Leukine/GM-CSF)]]
+
 
 +
 
 +
*[[Sacituzumab govitecan (Trodelvy)]]
 +
*[[Samarium-153 (Quadramet)]]
 +
*[[Selinexor (Xpovio)]]
 +
*[[Selpercatinib (Retevmo)]]
 +
*[[Selumetinib (Koselugo)]]
 +
*[[Serplulimab (Hansizhuang)]]
 +
*[[Sintilimab (Tyvyt)]]
 
*[[Sipuleucel-T (Provenge)]]
 
*[[Sipuleucel-T (Provenge)]]
 +
*[[Sirolimus protein-bound particles (Fyarro)]]
 +
*[[Sonidegib (Odomzo)]]
 
*[[Sorafenib (Nexavar)]]
 
*[[Sorafenib (Nexavar)]]
 +
*[[Sotorasib (Lumakras)]]
 +
*[[Stilbamidine]]
 
*[[Streptozocin (Zanosar)]]
 
*[[Streptozocin (Zanosar)]]
 +
*[[Strontium-89 (Metastron)]]
 +
*[[Sugemalimab (Cejemly)]]
 
*[[Sunitinib (Sutent)]]
 
*[[Sunitinib (Sutent)]]
 +
*[[Suramin (Antrypol)]]
  
 
==T==
 
==T==
 +
*[[Tabelecleucel (Ebvallo)]]
 +
*[[Tafasitamab (Monjuvi)]]
 +
*[[Tagraxofusp (Elzonris)]]
 +
*[[Talazoparib (Talzenna)]]
 +
*[[Talimogene laherparepvec (Imlygic)]]
 +
*[[Taloporfin (Laserphyrin)]]
 +
*[[Talquetamab (Talvey)]] '''FDA approved 2023-08-09'''
 +
*[[Tamibarotene (Amnoid)]]
 
*[[Tamoxifen (Nolvadex)]]
 
*[[Tamoxifen (Nolvadex)]]
−
*[[Temozolmide (Temodar)]]
+
*[[Tarlatamab (Imdelltra)]] '''FDA approved 2024-05-16'''
 +
*[[Tasonermin (Beromun)]]
 +
*[[Tazemetostat (Tazverik)]]
 +
*[[Tebentafusp (Kimmtrak)]]
 +
*[[Teclistamab (Tecvayli)]]
 +
*[[Tegafur and uracil (UFT)]]
 +
*[[Tegafur, gimeracil, oteracil (Teysuno, S-1)]]
 +
*[[Temoporfin (Foscan)]]
 +
*[[Temozolomide (Temodar)]]
 
*[[Temsirolimus (Torisel)]]
 
*[[Temsirolimus (Torisel)]]
 
*[[Teniposide (Vumon)]]
 
*[[Teniposide (Vumon)]]
 +
*[[Tepotinib (Tepmetko)]]
 
*[[Thalidomide (Thalomid)]]
 
*[[Thalidomide (Thalomid)]]
 
*[[Thioguanine (Tabloid)]]
 
*[[Thioguanine (Tabloid)]]
 +
*[[Thiotepa (Tepadina)]]
 
*[[Thiotepa (Thioplex)]]
 
*[[Thiotepa (Thioplex)]]
 +
*[[Tirabrutinib (Velexbru)]]
 +
*[[Tisagenlecleucel (Kymriah)]]
 +
*[[Tisotumab vedotin (Tivdak)]]
 
*[[Topotecan (Hycamtin)]]
 
*[[Topotecan (Hycamtin)]]
 
*[[Toremifene (Fareston)]]
 
*[[Toremifene (Fareston)]]
−
*[[Tositumomab & I-131 (Bexxar)]]
+
*[[Toripalimab (Loqtorzi)]] '''FDA approved 2023-10-27'''
 +
*[[Tositumomab and I-131 (Bexxar)]]
 +
*[[Tovorafenib (Ojemda)]] '''FDA approved 2024-04-23'''
 
*[[Trabectedin (Yondelis)]]
 
*[[Trabectedin (Yondelis)]]
 +
*[[Trametinib (Mekinist)]]
 
*[[Trastuzumab (Herceptin)]]
 
*[[Trastuzumab (Herceptin)]]
−
*[[Tretinoin (Vesanoid)]]
+
**[[Trastuzumab-anns (Kanjinti)]]
−
*[[Trimethoprim/Sulfamethoxazole (Bactrim DS)]]
+
**[[Trastuzumab-dkst (Ogivri)]]
 +
**[[Trastuzumab-dttb (Ontruzant)]]
 +
**[[Trastuzumab-herw (Herwenda)]]
 +
**[[Trastuzumab-pkrb (Herzuma)]]
 +
**[[Trastuzumab-qyyp (Trazimera)]]
 +
**[[Trastuzumab-strf (Hercessi)]] '''FDA approved 2024-04-29'''
 +
**[[Trastuzumab-zerc (Zercepac)]]
 +
*[[Trastuzumab and hyaluronidase (Herceptin Hylecta)]]
 +
*[[Trastuzumab deruxtecan (Enhertu)]]
 +
*[[Trastuzumab emtansine (Kadcyla)]]
 +
*[[Tremelimumab (Imjudo)]]
 +
*[[Treosulfan (Ovastat)]]
 +
*[[Trifluridine and tipiracil (Lonsurf)]]
 +
*[[Trilostane (Vetoryl)]]
 +
*[[Trimetrexate (Neutrexin)]]
 
*[[Triptorelin (Trelstar LA)]]
 
*[[Triptorelin (Trelstar LA)]]
 +
*[[Trofosfamide (Ixoten)]]
 +
*[[Tucatinib (Tukysa)]]
  
 
==U==
 
==U==
−
*[[Uracil-tegafur (UFT)]]
+
*[[Ublituximab (Briumvi)]] '''FDA approved 2023-01-06'''
−
 
 
 
==V==
 
==V==
 +
*[[Valemetostat (Ezharmia)]]
 +
*[[Valrubicin (Valstar)]]
 +
*[[Vandetanib (Caprelsa)]]
 +
*[[Vemurafenib (Zelboraf)]]
 +
*[[Venetoclax (Venclexta)]]
 
*[[Vinblastine (Velban)]]
 
*[[Vinblastine (Velban)]]
 
*[[Vincristine (Oncovin)]]
 
*[[Vincristine (Oncovin)]]
 
*[[Vindesine (Eldisine)]]
 
*[[Vindesine (Eldisine)]]
 +
*[[Vinflunine (Javlor)]]
 
*[[Vinorelbine (Navelbine)]]
 
*[[Vinorelbine (Navelbine)]]
 +
*[[Vismodegib (Erivedge)]]
 
*[[Vorinostat (Zolinza)]]
 
*[[Vorinostat (Zolinza)]]
 +
*[[Voxelotor (Oxbryta)]]
 +
 +
==Z==
 +
 +
*[[Zanubrutinib (Brukinsa)]]
 +
*[[Zimberelimab (Yu Duo)]]
 +
*[[Ziv-aflibercept (Zaltrap)]]
 +
**[[Aflibercept-jbvf (Yesafili)]] '''FDA approved 2024-05'''
 +
**[[Aflibercept-yszy (Opuviz)]] '''FDA approved 2024-05'''
 +
 +
=Discontinued antineoplastics=
 +
''This section contains drugs that have had at least one formal approval in any domain (FDA, EMA, etc), but are no longer on the market. Note that it is possible that these drugs continue to be available in some limited way, such as through compassionate use programs.
 +
 +
==A==
 +
 +
*[[Aminopterin]]
 +
*[[Asparaginase (Elspar)]]
 +
 +
==D==
 +
 +
*[[Daunorubicin liposomal (DaunoXome)]]
 +
*[[Denileukin diftitox (Ontak)]]
 +
*[[Diethylstilbestrol (DES)]]
 +
 +
==E==
 +
 +
*[[Edrecolomab (Panorex)]]
 +
*[[Ethinylestradiol]]
 +
 +
==F==
 +
 +
*[[Floxuridine (FUDR)]]
 +
*[[Fluoxymesterone (Halotestin)]]
 +
*[[Formestane (Lentaron)]]
 +
 +
==L==
 +
 +
*[[Levamisole (Ergamisol)]]
 +
 +
==M==
 +
 +
*[[Melphalan flufenamide (Pepaxto)]]
 +
 +
==O==
 +
 +
*[[Olaratumab (Lartruvo)]]
 +
 +
==P==
 +
*[[Paclitaxel poliglumex (Opaxio)]]
 +
*[[Plicamycin (Mithracin)]]
 +
*[[Polyestradiol phosphate (Estradurin)]]
 +
 +
==S==
 +
 +
*[[Semustine (MeCCNU)]]
 +
 +
==T==
 +
*[[Testolactone (Teslac)]]
 +
*[[Triethylenemelamine (Tretamine)]]
 +
 +
==U==
 +
*[[Umbralisib (Ukoniq)]]
 +
*[[Uracil mustard]]
 +
*[[Urethane]]
 +
 +
==V==
 +
*[[Vincristine liposomal (Marqibo)]]
 +
 +
=Investigational antineoplastics=
 +
''This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.''
 +
==A==
 +
 +
*[[Abexinostat (PCI-24781)]]
 +
*[[Actinium Ac 225 lintuzumab (Actimab-A)]]
 +
*[[Adavosertib (MK-1775)]]
 +
*[[Adebrelimab (SHR-1316)]]
 +
*[[Adenovirus-interferon-γ (TG-1042)]]
 +
*[[Afamitresgene Autoleucel (ADP-A2M4)]]
 +
*[[Afuresertib (GSK-2110183)]]
 +
*[[Agatolimod (PF-3512676)]]
 +
*[[Alisertib (MLN-8237)]]
 +
*[[Amatuximab (MORAb-009)]]
 +
*[[Amonafide (Quinamed)]]
 +
*[[Apocept (APG-101)]]
 +
*[[Astuprotimut-R (GSK-1572932A)]]
 +
 +
==B==
 +
 +
*[[Barasertib (AZD-1152)]]
 +
*[[Bavituximab (PGN-401)]]
 +
*[[Befotertinib (D-0316)]]
 +
*[[Belagenpumatucel-L (Lucanix)]]
 +
*[[BE-CAR7]]
 +
*[[BHQ-880]]
 +
*[[Birtamimab (NEOD-001)]]
 +
*[[BL22 immunotoxin (CAT-3888)]]
 +
*[[Buparlisib (BKM-120)]]
 +
 +
==C==
 +
*[[CARv3-TEAM-E T-cells]]
 +
*[[Catumaxomab (Removab)]] '''in US clinical trials'''
 +
*[[Cediranib (Recentin)]]
 +
*[[Cixutumumab (IMC-A12)]]
 +
*[[Coltuximab ravtansine (SAR-3419)]]
 +
*[[Crenolanib (CP-868,596)]]
 +
*[[Custirsen (OGX-011)]]
 +
 +
==D==
 +
 +
*[[Dalpiciclib (SHR-6390)]]
 +
*[[Danicopan (ALXN-2040)]]
 +
*[[Datopotamab deruxtecan (DS-1062)]]
 +
*[[Denintuzumab mafodotin (SGN-CD19A)]]
 +
*[[Dinaciclib (SCH-727965)]]
 +
*[[Divarasib (GDC-6036)]]
 +
*[[Discodermolide (XAA-296)]]
 +
*[[DMUC-5754A]]
 +
*[[Dovitinib (TKI-258)]]
 +
 +
==E==
 +
*[[Emepepimut-S (Stimuvax)]]
 +
*[[Eluvixtamab (AMG-330)]]
 +
*[[Entinostat (SNDX-275)]]
 +
*[[Entospletinib (GS-9973)]]
 +
*[[Envonalkib (TQ-B3139)]]
 +
*[[Epratuzumab (LymphoCide)]]
 +
*[[Etirinotecan pegol (NKTR-102)]]
 +
 +
==F==
 +
*[[Farletuzumab (MORAb-003)]]
 +
*[[Figitumumab (CP-751,871)]]
 +
*[[Filanesib (ARRY-520)]]
 +
 +
==G==
 +
*[[G207]]
 +
*[[Galeterone (TOK-001)]]
 +
*[[Galunisertib (LY-2157299)]]
 +
*[[Ganetespib (STA-9090)]]
 +
*[[Ganitumab (AMG-479)]]
 +
*[[GD2-CART01]]
 +
*[[Gemcitabine elaidate (CP-4126)]]
 +
*[[Glembatumumab vedotin (CDX-011)]]
 +
*[[Guadecitabine (SGI-110)]]
 +
 +
==H==
 +
 +
*[[HER2 peptide vaccine (AE37)]]
 +
*[[Hu5F9-G4]]
 +
 +
==I==
 +
 +
*[[Idasanutlin (RG-7388)]]
 +
*[[IMA-901]]
 +
*[[Indatuximab ravtansine (BT-062)]]
 +
*[[Ipatasertib (GDC-0068)]]
 +
*[[IPH-2101]]
 +
 +
==J==
 +
 +
*[[JCAR015]]
 +
 +
==L==
 +
 +
*[[Lapuleucel-T (DN24-02)]]
 +
*[[Lestaurtinib (CEP-701)]]
 +
*[[Linifanib (ABT-869)]]
 +
*[[Linsitinib (OSI-906)]]
 +
*[[Lorvotuzumab mertansine (BB-10901)]]
 +
*[[Lutetium-177-PSMA-617]]
 +
*[[LY-3023414]]
 +
 +
==M==
 +
*[[Magrolimab (Hu5F9-G4)]]
 +
*[[Mapatumumab (HGS-ETR1)]]
 +
*[[Masitinib (AB-1010)]]
 +
*[[MCARH-109]]
 +
*[[Mezigdomide (BMS-986348)]]
 +
*[[Milataxel (TL-139)]]
 +
*[[MK-2206]]
 +
*[[Mocetinostat (MGCD-0103)]]
 +
*[[Motesanib (AMG-706)]]
 +
 +
==N==
 +
*[[Nolatrexed (Thymitaq)]]
 +
 +
==O==
 +
*[[Oblimersen (Genasense)]]
 +
*[[Olaptesed pegol (NOX-A12)]]
 +
*[[Onartuzumab (MetMAb)]]
 +
*[[Oprozomib (ONX-0912)]]
 +
*[[Orteronel (TAK-700)]]
 +
*[[Osocimab (BAY-1213790)]]
 +
*[[Otlertuzumab (TRU-016)]]
 +
 +
==P==
 +
*[[Patritumab deruxtecan (U3-1402)]]
 +
*[[Pentraxin 2 (PRM-151)]]
 +
*[[Perifosine (KRX-0401)]]
 +
*[[Phosphomannopentaose sulfate (PI-88)]]
 +
*[[Pictilisib (GDC-0941)]]
 +
*[[Pidilizumab (CT-011)]]
 +
*[[Pimitespib (TAS-116)]]
 +
*[[Pinatuzumab vedotin (DCDT-2980S)]]
 +
*[[Plinabulin (NPI-2358)]]
 +
*[[Pracinostat (SB-939)]]
 +
 +
==Q==
 +
*[[Quisinostat (JNJ-26481585)]]
 +
 +
==R==
 +
*[[Rebimastat (BMS-275291)]]
 +
*[[Refametinib (BAY-869766)]]
 +
*[[Reovirus (Reolysin)]]
 +
*[[Retaspimycin (IPI-504)]]
 +
*[[Revumenib (SNDX-5613)]]
 +
*[[Rezvilutamide (SHR-3680)]]
 +
*[[Ricolinostat (ACY-1215)]]
 +
*[[Ridaforolimus (AP-23573)]]
 +
*[[Rilotumumab (AMG-102)]]
 +
*[[Ripertamab (SCT-400)]]
 +
*[[Rociletinib (CO-1686)]]
 +
 +
==S==
 +
 +
*[[Sapacitabine (CS-682)]]
 +
*[[Sapanisertib (MLN-0128)]]
 +
*[[Seliciclib (CYC-202)]]
 +
*[[Semuloparin (AVE-5026)]]
 +
*[[Spebrutinib (CC-292)]]
 +
*[[Surufatinib (HMPL-012)]]
 +
 +
==T==
 +
 +
*[[Tabalumab (LY-2127399)]]
 +
*[[Tasadenoturev (DNX-2401)]]
 +
*[[Telisotuzumab vedotin (ABBV-399)]]
 +
*[[Tertomotide (GV-1001)]]
 +
*[[Tesetaxel (DJ-927)]]
 +
*[[Tesevatinib (XL-647)]]
 +
*[[Tigatuzumab (CS-1008)]]
 +
*[[Tipifarnib (Zarnestra)]]
 +
*[[Tirapazamine (Tirazone)]]
 +
*[[Tislelizumab (Baizean)]]
 +
*[[Tivantinib (ARQ-197)]]
 +
*[[Tivozanib (AV-951)]]
 +
*[[Tosedostat (CHR-2797)]]
 +
*[[Trebananib (AMG-386)]]
 +
*[[Tusamitamab ravtansine (SAR-408701)]]
 +
 +
==U==
 +
*[[UCART19]]
 +
 +
==V==
 +
 +
*[[Vadastuximab talirine (SGN-CD33A)]]
 +
*[[Vadimezan (AS-A404)]]
 +
*[[Varlilumab (CDX-1127)]]
 +
*[[Veliparib (ABT-888)]]
 +
*[[Veltuzumab (hA20)]]
 +
*[[Volasertib (BI-6727)]]
 +
*[[Vorasidenib (AG-881)]]
 +
*[[Vorolanib (CM-082)]]
 +
*[[Vosaroxin (SNS-595)]]
 +
*[[Voxtalisib (XL-765)]]
 +
 +
==Z==
 +
 +
*[[Zandelisib (ME-401)]]
 +
*[[Zolbetuximab (IMAB-362)]]
 +
 +
=Supportive and other medications=
 +
''This section contains supportive drugs that are either approved or investigational. Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound.''
 +
==A==
 +
 +
*[[Abciximab (ReoPro)]]
 +
*[[Acetaminophen (Tylenol)]]
 +
*[[Acetazolamide (Diamox)]]
 +
*[[Acyclovir (Zovirax)]]
 +
*[[ADAMTS13, recombinant (Adzynma)]]
 +
*[[Alendronate (Fosamax)]]
 +
*[[Alizapride (Litican)]]
 +
*[[Allopurinol (Zyloprim)]]
 +
*[[Alprazolam (Xanax)]]
 +
*[[Aminocaproic acid (Amicar)]]
 +
*[[Amoxicillin]]
 +
*[[Anagrelide (Agrylin)]]
 +
*[[Andexanet alfa (Andexxa)]]
 +
*[[Anti-inhibitor coagulant complex (FEIBA NF)]]
 +
*[[Antithrombin III (human and recombinant)]]
 +
*[[Antithymocyte globulin, horse ATG (Atgam)]]
 +
*[[Antithymocyte globulin, rabbit ATG (Grafalon)]]
 +
*[[Antithymocyte globulin, rabbit ATG (Thymoglobulin)]]
 +
*[[Apixaban (Eliquis)]]
 +
*[[Aprepitant (Emend)]]
 +
*[[Argatroban (Acova)]]
 +
*[[Aripiprazole (Abilify)]]
 +
*[[Ascorbic acid (Vitamin C)]]
 +
*[[Aspirin]]
 +
*[[Aspirin and dipyridamole (Aggrenox)]]
 +
*[[Atropine (Atropen)]]
 +
*[[Atovaquone (Mepron)]]
 +
*[[Avatrombopag (Doptelet)]]
 +
*[[Azathioprine (Imuran)]]
 +
 +
==B==
 +
*[[Betibeglogene autotemcel (Zynteglo)]]
 +
*[[Betrixaban (Bevyxxa)]]
 +
*[[Bismuth subsalicylate (Pepto-Bismol)]]
 +
*[[Bivalirudin (Angiomax)]]
 +
 +
==C==
 +
 +
*[[Cangrelor (Kengreal)]]
 +
*[[Calcium phosphate rinse (Caphosol)]]
 +
*[[Caspofungin (Cancidas)]]
 +
*[[Cetirizine (Zyrtec)]]
 +
*[[Chlorpheniramine (Chlor-Trimeton)]]
 +
*[[Cilostazol (Pletal)]]
 +
*[[Cimetidine (Tagamet)]]
 +
*[[Ciprofloxacin (Cipro)]]
 +
*[[Clarithromycin (Biaxin)]]
 +
*[[Clemastine (Tavist)]]
 +
*[[Clodronate (Bonefos)]]
 +
*[[Clopidogrel (Plavix)]]
 +
*[[Concizumab (Alhemo)]]
 +
*[[Crizanlizumab (Adakveo)]]
 +
*[[Cyanocobalamin (Vitamin B12)]]
 +
*[[Cyclosporine]]
 +
*[[Cytomegalovirus Immune Globulin (Cytogam)]]
 +
 +
==D==
 +
 +
*[[Dabigatran (Pradaxa)]]
 +
*[[Dalteparin (Fragmin)]]
 +
*[[Danazol (Danocrine)]]
 +
*[[Dapsone (Aczone)]]
 +
*[[Darbepoetin alfa (Aranesp)]]
 +
*[[Deferasirox (Exjade)]]
 +
*[[Deferasirox (Jadenu)]]
 +
*[[Deferiprone (Ferriprox)]]
 +
*[[Deferoxamine (Desferal)]]
 +
*[[Defibrotide (Defitelio)]]
 +
*[[Denosumab (Xgeva)]]
 +
**[[Denosumab-bddz (Wyost)]]
 +
*[[Desmopressin (DDAVP)]]
 +
*[[Dexchlorpheniramine (Polaramine)]]
 +
*[[Dexrazoxane (Zinecard)]]
 +
*[[Diphenhydramine (Benadryl)]]
 +
*[[Dipyridamole (Persantine)]]
 +
*[[Docusate (Colace)]]
 +
*[[Dolasetron (Anzemet)]]
 +
*[[Domperidone (Motilium)]]
 +
*[[Doxycycline]]
 +
*[[Dronabinol (Marinol)]]
 +
 +
==E==
 +
*[[Eculizumab (Soliris)]]
 +
**[[Eculizumab-beke (Bekemv)]]
 +
**[[Eculizumab-epys (Epysqli)]]
 +
*[[Edoxaban (Savaysa)]]
 +
*[[Efanesoctocog alfa (Altuviiio)]]
 +
*[[Eflapegrastim (Rolvedon)]]
 +
*[[Eltrombopag (Promacta)]]
 +
*[[Emicizumab (Hemlibra)]]
 +
*[[Enoxaparin (Lovenox)]]
 +
**[[Enoxaparin-inhi (Inhixa)]]
 +
*[[Epoetin alfa (Procrit)]]
 +
**[[Epoetin alfa-epbx (Retacrit)]]
 +
**[[Epoetin alfa-abse (Abseamed)]]
 +
**[[Epoetin alfa-bino (Binocrit)]]
 +
**[[Epoetin alfa-hexa (Epoetin Alfa Hexal)]]
 +
*[[Epoetin theta (Biopoin)]]
 +
*[[Epoetin zeta (Eprex)]]
 +
**[[Epoetin zeta-reta (Retacrit)]]
 +
**[[Epoetin zeta-sila (Silapo)]]
 +
*[[Eptifibatide (Integrilin)]]
 +
*[[Etranacogene dezaparvovec (Hemgenix)]]
 +
*[[Exagamglogene autotemcel (Casgevy)]] '''FDA approved on 2023-12-08'''
 +
 +
==F==
 +
 +
*[[Factor VIIa, recombinant (NovoSeven RT)]]
 +
*[[Factor VIII, human]]
 +
*[[Factor VIII, recombinant]]
 +
*[[Factor IX, human]]
 +
*[[Factor IX, recombinant]]
 +
*[[Factor IX, recombinant, Fc fusion protein (Alprolix)]]
 +
*[[Factor X, human (Coagadex)]]
 +
*[[Factor XIII concentrate, human (Corifact)]]
 +
*[[Famciclovir (Famvir)]]
 +
*[[Famotidine (Pepcid)]]
 +
*[[Ferric carboxymaltose (Injectafer)]]
 +
*[[Ferric derisomaltose (Monoferric)]]
 +
*[[Ferric gluconate (Ferrlecit)]]
 +
*[[Ferrous sulfate (Feosol)]]
 +
*[[Ferumoxytol (Feraheme)]]
 +
*[[Fibrinogen concentrate, human (RiaSTAP)]]
 +
*[[Filgrastim (Neupogen)]]
 +
**[[Filgrastim-aafi (Nivestym)]]
 +
**[[Filgrastim-ayow (Releuko)]]
 +
**[[Filgrastim-sndz (Zarxio)]]
 +
**[[Filgrastim-acco (Accofil)]]
 +
**[[Filgrastim-hexa (Filgrastim Hexal)]]
 +
**[[Filgrastim-gras (Grastofil)]]
 +
**[[Filgrastim-rati (Ratiograstim)]]
 +
**[[Filgrastim-teva (Tevagrastim)]]
 +
*[[Finasteride (Proscar)]]
 +
*[[Fitusiran (ALN-AT3SC)]]
 +
*[[Fluconazole (Diflucan)]]
 +
*[[Folic acid (Folate)]]
 +
*[[Fondaparinux (Arixtra)]]
 +
*[[Fosaprepitant (Emend for Injection)]]
 +
*[[Fosnetupitant (Arokaris)]]
 +
*[[Furosemide (Lasix)]]
 +
 +
==G==
 +
 +
*[[Glucarpidase (Voraxaze)]]
 +
*[[Granisetron]]
 +
 +
==H==
 +
 +
*[[Haloperidol (Haldol)]]
 +
*[[Hematopoetic progenitor cells, cord blood (Hemacord)]]
 +
 +
==I==
 +
 +
*[[Ibandronate (Boniva)]]
 +
*[[Idarucizumab (Praxbind)]]
 +
*[[Indomethacin (Indocin)]]
 +
*[[Iptacopan (Fabhalta)]] '''FDA approved 2023-12-05'''
 +
*[[Iron dextran (INFeD)]]
 +
*[[Iron sucrose (Venofer)]]
 +
*[[Itraconazole (Sporanox)]]
 +
 +
==L==
 +
 +
*[[Lactulose]]
 +
*[[Lamivudine (Epivir)]]
 +
*[[Lansoprazole (Prevacid)]]
 +
*[[Lenograstim (Granocyte)]]
 +
*[[Lepirudin (Refludan)]] '''discontinued'''
 +
*[[Letermovir (Prevymis)]]
 +
*[[Levofloxacin (Levaquin)]]
 +
*[[L-glutamine (Endari)]]
 +
*[[Lipefilgrastim (Lonquex)]]
 +
*[[Loperamide (Imodium)]]
 +
*[[Lorazepam (Ativan)]]
 +
*[[Lovotibeglogene autotemcel (Lyfgenia)]] '''FDA approved on 2023-12-08'''
 +
*[[Luspatercept (Reblozyl)]]
 +
*[[Lusutrombopag (Mulpleta)]]
 +
 +
==M==
 +
 +
 +
*[[Mannitol]]
 +
*[[Meperidine (Demerol)]]
 +
*[[Mesna (Mesnex)]]
 +
*[[Methyltesterone (Android)]]
 +
*[[Metoclopramide (Reglan)]]
 +
*[[Mitapivat (Pyrukynd)]]
 +
*[[Motixafortide (Aphexda)]] '''FDA approved 2023-09'''
 +
*[[Mycophenolate mofetil (CellCept)]]
 +
 +
==N==
 +
 +
 +
*[[Nabilone (Cesamet)]]
 +
*[[Netupitant and palonosetron (Akynzeo)]]
 +
*[[Nonacog beta pegol (Refixia)]]
 +
 +
==O==
 +
 +
*[[Olanzapine (Zyprexa)]]
 +
*[[Omeprazole (Prilosec)]]
 +
*[[Omidubicel (Omisirge)]] '''FDA approved 2023-04-17'''
 +
*[[Ondansetron (Zofran)]]
 +
*[[Oprelvekin (Neumega)]]
 +
 +
==P==
 +
 +
 +
*[[Palifermin (Kepivance)]]
 +
*[[Palonosetron (Aloxi)]]
 +
*[[Pamidronate (Aredia)]]
 +
*[[Pantoprazole (Protonix)]]
 +
*[[Pegfilgrastim (Neulasta)]]
 +
**[[Pegfilgrastim-apgf (Nyvepria)]]
 +
**[[Pegfilgrastim-bmez (Ziextenzo)]]
 +
**[[Pegfilgrastim-cbqv (Udenyca)]]
 +
**[[Pegfilgrastim-fpgk (Stimufend)]]
 +
**[[Pegfilgrastim-jmdb (Fulphila)]]
 +
**[[Pegfilgrastim-cegf (Cegfila)]]
 +
**[[Pegfilgrastim-gras (Grasustek)]]
 +
**[[Pegfilgrastim-pbbk (Fylnetra)]]
 +
**[[Pegfilgrastim-pelg (Pelgraz)]]
 +
**[[Pegfilgrastim-pelm (Pelmeg)]]
 +
**[[Pegfilgrastim-stim (Stimufend)]]
 +
*[[Penicillin V]]
 +
*[[Pentamidine (Nebupent)]]
 +
*[[Phenytoin (Dilantin)]]
 +
*[[Phytonadione (Vitamin K)]]
 +
*[[Plerixafor (Mozobil)]]
 +
*[[Prasugrel (Effient)]]
 +
*[[Pravastatin (Pravachol)]]
 +
*[[Prochlorperazine (Compazine)]]
 +
*[[Promethazine (Phenergan)]]
 +
*[[Protamine sulfate]]
 +
*[[Protein C, human (Ceprotin)]]
 +
*[[Prothrombin Complex Concentrate, human]]
 +
 +
==Q==
 +
 +
*[[Quinine (Qualaquin)]]
 +
 +
==R==
 +
*[[Rabeprazole (Aciphex)]]
 +
*[[Raloxifene (Evista)]]
 +
*[[Ramosetron (Iribo)]]
 +
*[[Ranitidine (Zantac)]]
 +
*[[Rasburicase (Elitek)]]
 +
*[[Remestemcel-L (Prochymal)]]
 +
*[[Rho(D) immune globulin (RhoGAM)]]
 +
*[[Rilzabrutinib (PRN-1008)]]
 +
*[[Risedronate (Actonel)]]
 +
*[[Rivaroxaban (Xarelto)]]
 +
*[[Rolapitant (Varubi)]]
 +
*[[Romiplostim (Nplate)]]
 +
*[[Rusfertide (PTG-300)]]
 +
 +
==S==
 +
 +
*[[Sargramostim (Leukine)]]
 +
*[[Scopolamine (Scopoderm)]]
 +
*[[Sennosides (Senna)]]
 +
*[[Siltuximab (Sylvant)]]
 +
*[[Sirolimus (Rapamune)]]
 +
*[[Sodium thiosulfate (Pedmark)]]
 +
*[[Sutimlimab (Enjaymo)]]
 +
 +
==T==
 +
 +
*[[Tacrolimus (Prograf)]]
 +
*[[Tbo-filgrastim (Granix)]]
 +
*[[Telotristat (Xermelo)]]
 +
*[[Ticagrelor (Brilinta)]]
 +
*[[Ticlopidine (Ticlid)]]
 +
*[[Tinzaparin (Innohep)]]
 +
*[[Tirofiban (Aggrastat)]]
 +
*[[Tocilizumab (Actemra)]]
 +
**[[Tocilizumab-aazg (Tyenne)]]
 +
**[[Tocilizumab-bavi (Tofidence)]]
 +
*[[Tofacitinib (Xeljanz)]]
 +
*[[Tranexamic acid (Cyklokapron)]]
 +
*[[Trilaciclib (Cosela)]]
 +
*[[Trimethoprim-Sulfamethoxazole (Bactrim DS)]]
 +
*[[Tropisetron (Navoban)]]
 +
 +
==U==
 +
*[[Unfractionated heparin (UFH)]]
 +
*[[Uridine triacetate (Vistogard)]]
 +
 +
==V==
 +
 +
*[[Valacyclovir (Valtrex)]]
 +
*[[Valganciclovir (Valcyte)]]
 +
*[[Valoctocogene roxaparvovec (AAV5-hFVIII-SQ)]]
 +
*[[Valproate (Depakote)]]
 +
*[[Verbrinacogene setparvovec (FLT-180a)]]
 +
*[[von Willebrand factor and factor VIII complex, human]]
 +
*[[von Willebrand factor, recombinant]]
 +
*[[Vonoprazan (Takecab)]]
 +
*[[Vorapaxar (Zontivity)]]
 +
*[[Voriconazole (Vfend)]]
 +
 +
==W==
 +
 +
 +
*[[Warfarin (Coumadin)]]
  
 
==Z==
 
==Z==
 
*[[Zoledronic acid (Zometa)]]
 
*[[Zoledronic acid (Zometa)]]
  
−
==Reference==
+
=By Category=
−
# [http://hemonc.org/docs/chemotherapysequences.pdf Chemotherapy Order of Administration (ONS recommendations-PDF)]
+
''Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is an ongoing process so not all of these links are active or current).''
−
# [http://chemocare.com/bio/ Chemocare.com]
+
 
 +
==[[:Category:REMS_program|Drugs in a REMS program]]==
 +
 
 +
==Cytotoxic Chemotherapy==
 +
 
 +
 
 +
*[[:Category:Alkylating agents|Alkylating agents]]
 +
*[[:Category:Anthracyclines|Anthracyclines]]
 +
*[[:Category:Antimetabolites|Antimetabolites]]
 +
*[[:Category:Human DNA synthesis inhibitors|DNA synthesis inhibitors]]
 +
*[[:Category:Microtubule inhibitors|Microtubule inhibitors]]
 +
*[[:Category:Nitrogen mustards|Nitrogen mustards]]
 +
*[[:Category:Nitrosureas|Nitrosureas]]
 +
*[[:Category:Platinum agents|Platinum agents]]
 +
*[[:Category:Proteasome inhibitors|Proteasome inhibitors]]
 +
*[[:Category:Taxanes|Taxanes]]
 +
*[[:Category:Topoisomerase inhibitors|Topoisomerase inhibitors]]
 +
*[[:Category:Vinca alkaloids|Vinca alkaloids]]
 +
 
 +
==[[:Category:Kinase inhibitors|Kinase inhibitors]]==
 +
 
 +
<div style="column-count:2;-moz-column-count:2;-webkit-column-count:2">
 +
*[[:Category:AKT1 inhibitors|AKT1 inhibitors]]
 +
*[[:Category:ALK inhibitors|ALK inhibitors]]
 +
*[[:Category:Aurora kinase inhibitors|Aurora kinase inhibitors]]
 +
*[[:Category:AXL inhibitors|AXL inhibitors]]
 +
*[[:Category:Bcr-Abl inhibitors|Bcr-Abl inhibitors]]
 +
*[[:Category:BRAF inhibitors|BRAF inhibitors]]
 +
*[[:Category:BTK inhibitors|BTK inhibitors]]
 +
*[[:Category:CDK inhibitors|CDK inhibitors]]
 +
*[[:Category:EGFR inhibitors|EGFR inhibitors]]
 +
*[[:Category:ERBB2 inhibitors|ERBB2 inhibitors]]
 +
*[[:Category:ERBB4 inhibitors|ERBB4 inhibitors]]
 +
*[[:Category:FGFR inhibitors|FGFR inhibitors]]
 +
*[[:Category:FLT3 inhibitors|FLT3 inhibitors]]
 +
*[[:Category:IGFR inhibitors|IGFR inhibitors]]
 +
*[[:Category:JAK inhibitors|JAK inhibitors]]
 +
*[[:Category:KIT inhibitors|KIT inhibitors]]
 +
*[[:Category:MEK inhibitors|MEK inhibitors]]
 +
*[[:Category:MET inhibitors|MET inhibitors]]
 +
*[[:Category:mTOR inhibitors|mTOR inhibitors]]
 +
*[[:Category:PDGFR inhibitors|PDGFR inhibitors]]
 +
*[[:Category:PI3K inhibitors|PI3K inhibitors]]
 +
*[[:Category:PLK1 inhibitors|PLK1 inhibitors]]
 +
*[[:Category:RET inhibitors|RET inhibitors]]
 +
*[[:Category:ROS1 inhibitors|ROS1 inhibitors]]
 +
*[[:Category:SRC inhibitors|SRC inhibitors]]
 +
*[[:Category:SYK inhibitors|SYK inhibitors]]
 +
*[[:Category:TEK inhibitors|TEK inhibitors]]
 +
*[[:Category:TRK inhibitors|TRK inhibitors]]
 +
*[[:Category:VEGFR inhibitors|VEGF inhibitors]]
 +
</div>
 +
 
 +
==[[:Category:Endocrine therapeutic|Endocrine therapy]]==
 +
 
 +
 
 +
*[[:Category:Antiandrogens|Antiandrogens]]
 +
*[[:Category:Steroid synthesis inhibitors|Steroid synthesis inhibitors]]
 +
*[[:Category:Androgen receptor inhibitors|Androgen receptor inhibitors]]
 +
*[[:Category:5 alpha-reductase inhibitors|5 alpha-reductase inhibitors]]
 +
*[[:Category:GnRH agonists|GnRH agonists]]
 +
*[[:Category:GnRH antagonists|GnRH antagonists]]
 +
*[[:Category:Aromatase inhibitors|Aromatase inhibitors]]
 +
*[[:Category:Selective estrogen receptor modulators|Selective estrogen receptor modulators]]
 +
*[[:Category:Steroids|Steroids]]
 +
*[[:Category:Somatostatin analogs|Somatostatin analogs]]
 +
 
 +
==Investigational and Discontinued==
 +
 
 +
*[[:Category:Investigational_drugs|Investigational]]
 +
*[[:Category:Discontinued_drugs|Discontinued]]
 +
 
 +
==Biologics==
 +
 
 +
 
 +
*[[:Category:Antibody medications|Antibody medications]]
 +
*[[:Category:Antibody-drug conjugates|Antibody-drug conjugates]]
 +
*[[:Category:Anti-HER2 medications|Anti-HER2 medications]]
 +
*[[:Category:IL-6 inhibitors|IL-6 inhibitors]]
 +
*[[:Category:Enzymes|Enzymes]]
 +
*[[:Category:Immunotherapeutic|Immunotherapy]]
 +
*[[:Category:Immunomodulatory drugs (IMiDs)|Immunomodulatory drugs (IMiDs)]]
 +
 
 +
==Supportive Medications==
 +
 
 +
 
 +
*[[:Category:Antibacterials|Antibacterials]]
 +
*[[:Category:Antidiarrheals|Antidiarrheals]]
 +
*[[:Category:Antifungals|Antifungals]]
 +
*[[:Category:Antihistamines|Antihistamines]]
 +
*[[:Category:Antivirals|Antivirals]]
 +
*[[:Category:Bisphosphonates|Bisphosphonates]]
 +
*[[:Category:Chemotherapy protective agents|Chemotherapy protective agents]]
 +
*[[:Category:Emesis prevention|Emesis prevention]]
 +
*[[:Category:PCP prophylaxis|PCP prophylaxis]]
 +
*[[:Category:RANK ligand inhibitors|RANK ligand inhibitors]]
 +
*[[:Category:Steroids|Steroids]]
 +
 
 +
==[[:Category:Radioactive agents|Radioactive agents]]==
 +
 
 +
*[[:Category:Alpha emitters|Alpha emitters]]
 +
*[[:Category:Radioimmunotherapy|Radioimmunotherapy]]
 +
 
 +
==[[:Category:Hematology medications|Benign Hematology Medications]]==
 +
 
 +
 
 +
*[[:Category:Anticoagulants|Anticoagulants]]
 +
**[[:Category:Direct thrombin inhibitors|Direct thrombin inhibitors (DTI)]]
 +
**[[:Category:Factor Xa inhibitors|Factor Xa inhibitors]]
 +
**[[:Category:Heparins|Heparins]]
 +
**[[:Category:Low molecular weight heparins|Low molecular weight heparins (LMWH)]]
 +
**[[:Category:Vitamin K antagonists|Vitamin K antagonists (VKA)]]
 +
*[[:Category:Antiplatelet agents|Antiplatelet agents (APA)]]
 +
**[[:Category:Phosphodiesterase inhibitors|Phosphodiesterase inhibitors]]
 +
**[[:Category:Cyclooxygenase inhibitors|Cyclooxygenase inhibitors]]
 +
**[[:Category:P2Y12 ADP inhibitors|P2Y12 ADP inhibitors]]
 +
*[[:Category:Hemostasis medications|Hemostasis medications]]
 +
**[[:Category:Coagulation factors|Coagulation factors]]
 +
**[[:Category:Fibrinolysis inhibitors|Fibrinolysis inhibitors]]
 +
**[[:Category:Vasopressin analogs|Vasopressin analogs]]
 +
*[[:Category:Chelators|Chelators]]
 +
 
 +
==[[:Category:Hematopoietic growth factors|Hematopoietic Growth Factors]]==
 +
 
 +
 
 +
*[[:Category:Erythrocyte growth factors|Erythrocyte growth factors]]
 +
*[[:Category:Granulocyte colony-stimulating factors|Granulocyte growth factors]]
 +
*[[:Category:Megakaryocyte growth factors|Megakaryocyte growth factors]]
 +
 
 +
==Miscellaneous==
 +
 
 +
 
 +
*[[:Category:REMS_program|Drugs in a REMS program]]
 +
*[[:Category:HDAC inhibitors|HDAC inhibitors]]
 +
*[[:Category:Hypomethylating agents|Hypomethylating agents]]
 +
*[[:Category:Retinoids|Retinoids]]
 +
*[[:Category:WHO_Essential_Cancer_Medicine|WHO Essential Cancer Medicines]]
 +
 
 +
==Medications by Condition==
 +
 
 +
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 +
*[[:Category:B-cell acute lymphoblastic leukemia medications|Acute lymphocytic leukemia medications]]
 +
*[[:Category:Acute myeloid leukemia medications|Acute myeloid leukemia medications]]
 +
*[[:Category:Acute promyelocytic leukemia medications|Acute promyelocytic leukemia medications]]
 +
*[[:Category:Anal cancer medications|Anal cancer medications]]
 +
*[[:Category:Anaplastic large cell lymphoma medications|Anaplastic large cell lymphoma medications]]
 +
*[[:Category:Bladder cancer medications|Bladder cancer medications]]
 +
*[[:Category:Bone cancer medications |Bone cancer medications]]
 +
*[[:Category:Breast cancer medications|Breast cancer medications]]
 +
*[[:Category:Burkitt lymphoma medications|Burkitt lymphoma medications]]
 +
*[[:Category:Cancer of unknown primary medications |Cancer of unknown primary medications]]
 +
*[[:Category:Castleman disease medications|Castleman disease medications]]
 +
*[[:Category:Central nervous system (CNS) cancer medications|Central nervous system (CNS) cancer medications]]
 +
*[[:Category:CNS lymphoma medications|Central nervous system (CNS) lymphoma medications]]
 +
*[[:Category:Cervical cancer medications|Cervical cancer medications]]
 +
*[[:Category:Chronic lymphocytic leukemia medications|Chronic lymphocytic leukemia (CLL/SLL) medications]]
 +
*[[:Category:Chronic myeloid leukemia medications|Chronic myeloid leukemia (CML) medications]]
 +
*[[:Category:Chronic myelomonocytic leukemia medications|Chronic myelomonocytic leukemia (CMML) medications]]
 +
*[[:Category:Colon cancer medications|Colon cancer medications]]
 +
*[[:Category:Colorectal cancer medications|Colorectal cancer (CRC) medications]]
 +
*[[:Category:Cutaneous basal cell carcinoma medications|Cutaneous BCC medications]]
 +
*[[:Category:Cutaneous squamous cell carcinoma medications|Cutaneous SCC medications]]
 +
*[[:Category:Cutaneous T-cell lymphoma medications|Cutaneous T-cell lymphoma medications]]
 +
*[[:Category:Diffuse large B-cell lymphoma medications|Diffuse large B-cell lymphoma medications]]
 +
*[[:Category:Endometrial cancer medications|Endometrial cancer medications]]
 +
*[[:Category:Esophageal cancer medications|Esophageal cancer medications]]
 +
*[[:Category:Essential thrombocythemia medications|Essential thrombocythemia medications]]
 +
*[[:Category:Extranodal NK- and T-cell lymphoma, nasal type medications|Extranodal NK/T-cell lymphoma, nasal type lymphoma medications]]
 +
*[[:Category:Follicular lymphoma medications|Follicular lymphoma medications]]
 +
*[[:Category:Gastric cancer medications|Gastric cancer medications]]
 +
*[[:Category:Hairy cell leukemia medications|Hairy cell leukemia medications]]
 +
*[[:Category:Head and neck cancer medications|Head and neck cancer medications]]
 +
*[[:Category:Hepatobiliary cancer medications|Hepatobiliary cancer medications]]
 +
*[[:Category:HIV-associated lymphoma medications|HIV-associated lymphoma medications]]
 +
*[[:Category:Hodgkin lymphoma medications|Hodgkin lymphoma medications]]
 +
*[[:Category:Hodgkin lymphoma, nodular lymphocyte-predominant medications|Hodgkin lymphoma, nodular lymphocyte-predominant medications]]
 +
*[[:Category:Immune thrombocytopenia medications|Immune thrombocytopenic purpura (ITP) medications]]
 +
*[[:Category:Light-chain (AL) amyloidosis medications|Light-chain (AL) amyloidosis medications]]
 +
*[[:Category:Mantle cell lymphoma medications|Mantle cell lymphoma medications]]
 +
*[[:Category:Marginal zone lymphoma medications|Marginal zone lymphoma medications]]
 +
*[[:Category:Mediastinal gray-zone lymphoma medications|Mediastinal gray-zone lymphoma medications]]
 +
*[[:Category:Melanoma medications |Melanoma medications]]
 +
*[[:Category:Mesothelioma medications|Mesothelioma medications]]
 +
*[[:Category:Multiple myeloma medications|Multiple myeloma medications]]
 +
*[[:Category:Myelodysplastic syndrome medications|Myelodysplastic syndrome medications]]
 +
*[[:Category:Myelofibrosis medications|Myelofibrosis medications]]
 +
*[[:Category:NK- and T-cell lymphoma medications|NK/T-cell lymphoma medications]]
 +
*[[:Category:Non-small cell lung cancer medications|Non-small cell lung cancer medications]]
 +
*[[:Category:Neuroendocrine tumor medications|Neuroendocrine tumor medications]]
 +
*[[:Category:Ovarian cancer medications|Ovarian cancer medications]]
 +
*[[:Category:Pancreatic cancer medications |Pancreatic cancer medications]]
 +
*[[:Category:Paroxysmal nocturnal hemoglobinuria medications|Paroxysmal nocturnal hemoglobinuria (PNH) medications]]
 +
*[[:Category:Penile cancer medications |Penile cancer medications]]
 +
*[[:Category:Peripheral T-cell lymphoma medications|Peripheral T-cell lymphoma medications]]
 +
*[[:Category:Plasma cell leukemia medications|Plasma cell leukemia medications]]
 +
*[[:Category:Polycythemia vera medications|Polycythemia vera medications]]
 +
*[[:Category:Primary mediastinal B-cell lymphoma medications|Primary mediastinal B-cell lymphoma medications]]
 +
*[[:Category:Prostate cancer medications|Prostate cancer medications]]
 +
*[[:Category:Rectal cancer medications|Rectal cancer medications]]
 +
*[[:Category:Renal cell carcinoma medications|Renal cell carcinoma medications]]
 +
*[[:Category:Sarcoma medications |Sarcoma medications]]
 +
*[[:Category:Sickle cell anemia medications|Sickle cell anemia medications]]
 +
*[[:Category:Small cell lung cancer medications|Small cell lung cancer medications]]
 +
*[[:Category:T-cell lymphoma medications|T-cell lymphoma medications]]
 +
*[[:Category:Testicular cancer medications|Testicular cancer medications]]
 +
*[[:Category:Thymoma medications|Thymoma medications]]
 +
*[[:Category:Thyroid cancer medications|Thyroid cancer medications]]
 +
*[[:Category:Transformed lymphoma medications|Transformed lymphoma medications]]
 +
*[[:Category:Transplant medications|Transplant medications]]
 +
*[[:Category:Waldenström macroglobulinemia medications|Waldenström macroglobulinemia medications]]
 +
</div>
 +
 
 +
==[[:Category:Routed medications|Medications by Route of Administration]]==
 +
 
 +
 
 +
*[[:Category:Intra-arterial medications|Intraarterial (IA) medications]]
 +
*[[:Category:Intracavitary medications|Intracavitary medications]]
 +
*[[:Category:Intramuscular medications|Intramuscular (IM) medications]]
 +
*[[:Category:Intrathecal medications|Intrathecal (IT) medications]]
 +
*[[:Category:Intravenous medications|Intravenous (IV) medications]]
 +
*[[:Category:Intravesical medications|Intravesicular medications]]
 +
*[[:Category:Oral medications|Oral (PO) medications]]
 +
*[[:Category:Subcutaneous medications|Subcutaneous (SC) medications]]
 +
 
 +
==Medications by FDA Year of Approval==
 +
 
 +
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 +
*[[:Category:FDA approved in 1939|FDA approved in 1939]]
 +
*[[:Category:FDA approved in 1941|FDA approved in 1941]]
 +
*[[:Category:FDA approved in 1946|FDA approved in 1946]]
 +
*[[:Category:FDA approved in 1949|FDA approved in 1949]]
 +
*[[:Category:FDA approved in 1951|FDA approved in 1951]]
 +
*[[:Category:FDA approved in 1952|FDA approved in 1952]]
 +
*[[:Category:FDA approved in 1953|FDA approved in 1953]]
 +
*[[:Category:FDA approved in 1954|FDA approved in 1954]]
 +
*[[:Category:FDA approved in 1955|FDA approved in 1955]]
 +
*[[:Category:FDA approved in 1956|FDA approved in 1956]]
 +
*[[:Category:FDA approved in 1957|FDA approved in 1957]]
 +
*[[:Category:FDA approved in 1958|FDA approved in 1958]]
 +
*[[:Category:FDA approved in 1959|FDA approved in 1959]]
 +
*[[:Category:FDA approved in 1962|FDA approved in 1962]]
 +
*[[:Category:FDA approved in 1963|FDA approved in 1963]]
 +
*[[:Category:FDA approved in 1964|FDA approved in 1964]]
 +
*[[:Category:FDA approved in 1965|FDA approved in 1965]]
 +
*[[:Category:FDA approved in 1966|FDA approved in 1966]]
 +
*[[:Category:FDA approved in 1967|FDA approved in 1967]]
 +
*[[:Category:FDA approved in 1968|FDA approved in 1968]]
 +
*[[:Category:FDA approved in 1969|FDA approved in 1969]]
 +
*[[:Category:FDA approved in 1970|FDA approved in 1970]]
 +
*[[:Category:FDA approved in 1971|FDA approved in 1971]]
 +
*[[:Category:FDA approved in 1973|FDA approved in 1973]]
 +
*[[:Category:FDA approved in 1974|FDA approved in 1974]]
 +
*[[:Category:FDA approved in 1975|FDA approved in 1975]]
 +
*[[:Category:FDA approved in 1976|FDA approved in 1976]]
 +
*[[:Category:FDA approved in 1977|FDA approved in 1977]]
 +
*[[:Category:FDA approved in 1978|FDA approved in 1978]]
 +
*[[:Category:FDA approved in 1979|FDA approved in 1979]]
 +
*[[:Category:FDA approved in 1980|FDA approved in 1980]]
 +
*[[:Category:FDA approved in 1981|FDA approved in 1981]]
 +
*[[:Category:FDA approved in 1982|FDA approved in 1982]]
 +
*[[:Category:FDA approved in 1983|FDA approved in 1983]]
 +
*[[:Category:FDA approved in 1984|FDA approved in 1984]]
 +
*[[:Category:FDA approved in 1985|FDA approved in 1985]]
 +
*[[:Category:FDA approved in 1986|FDA approved in 1986]]
 +
*[[:Category:FDA approved in 1987|FDA approved in 1987]]
 +
*[[:Category:FDA approved in 1988|FDA approved in 1988]]
 +
*[[:Category:FDA approved in 1989|FDA approved in 1989]]
 +
*[[:Category:FDA approved in 1990|FDA approved in 1990]]
 +
*[[:Category:FDA approved in 1991|FDA approved in 1991]]
 +
*[[:Category:FDA approved in 1992|FDA approved in 1992]]
 +
*[[:Category:FDA approved in 1993|FDA approved in 1993]]
 +
*[[:Category:FDA approved in 1994|FDA approved in 1994]]
 +
*[[:Category:FDA approved in 1995|FDA approved in 1995]]
 +
*[[:Category:FDA approved in 1996|FDA approved in 1996]]
 +
*[[:Category:FDA approved in 1997|FDA approved in 1997]]
 +
*[[:Category:FDA approved in 1998|FDA approved in 1998]]
 +
*[[:Category:FDA approved in 1999|FDA approved in 1999]]
 +
*[[:Category:FDA approved in 2000|FDA approved in 2000]]
 +
*[[:Category:FDA approved in 2001|FDA approved in 2001]]
 +
*[[:Category:FDA approved in 2002|FDA approved in 2002]]
 +
*[[:Category:FDA approved in 2003|FDA approved in 2003]]
 +
*[[:Category:FDA approved in 2004|FDA approved in 2004]]
 +
*[[:Category:FDA approved in 2005|FDA approved in 2005]]
 +
*[[:Category:FDA approved in 2006|FDA approved in 2006]]
 +
*[[:Category:FDA approved in 2007|FDA approved in 2007]]
 +
*[[:Category:FDA approved in 2008|FDA approved in 2008]]
 +
*[[:Category:FDA approved in 2009|FDA approved in 2009]]
 +
*[[:Category:FDA approved in 2010|FDA approved in 2010]]
 +
*[[:Category:FDA approved in 2011|FDA approved in 2011]]
 +
*[[:Category:FDA approved in 2012|FDA approved in 2012]]
 +
*[[:Category:FDA approved in 2013|FDA approved in 2013]]
 +
*[[:Category:FDA approved in 2014|FDA approved in 2014]]
 +
*[[:Category:FDA approved in 2015|FDA approved in 2015]]
 +
*[[:Category:FDA approved in 2016|FDA approved in 2016]]
 +
*[[:Category:FDA approved in 2017|FDA approved in 2017]]
 +
*[[:Category:FDA approved in 2018|FDA approved in 2018]]
 +
*[[:Category:FDA approved in 2019|FDA approved in 2019]]
 +
*[[:Category:FDA approved in 2020|FDA approved in 2020]]
 +
*[[:Category:FDA approved in 2021|FDA approved in 2021]]
 +
*[[:Category:FDA approved in 2022|FDA approved in 2022]]
 +
*[[:Category:FDA approved in 2023|FDA approved in 2023]]
 +
*[[:Category:FDA approved in 2024|FDA approved in 2024]]
 +
</div>
 +
 
 +
=Interesting and Helpful Links=
 +
 
 +
 
 +
*[[Antidepressants and other psychiatric medications in cancer care]]
 +
*[[Antiemesis|Antiemetic support]]
 +
*[https://doi.org/10.1200/JCO.2012.45.8661 Antimicrobial Prophylaxis and Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology Clinical Practice Guideline (2013)]
 +
*[https://doi.org/10.1200/JOP.2016.017905 2016 Updated American Society of Clinical Oncology/Oncology Nursing Society (ASCO/ONS) Chemotherapy Administration Safety Standards, Including Standards for Pediatric Oncology]
 +
*[http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p Chemotherapy Administration Sequence]<ref>Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. [http://issuu.com/theoncologypharmacist/docs/jhop_march2011/1?mode=a_p link to original article]</ref> - with chemotherapy sequencing chart
 +
*[https://doi.org/10.1111/j.1743-7563.2010.01321.x The Clinical Oncological Society of Australia (COSA) guidelines for the safe prescribing, dispensing and administration of cancer chemotherapy.] [https://pubmed.ncbi.nlm.nih.gov/20887505/ PubMed]
 +
*[https://crediblemeds.org/ CredibleMeds.org] - lists of QT-prolonging drugs; requires free registration to see full list
 +
*[http://www.accessdata.fda.gov/scripts/drugshortages/default.cfm FDA drug shortages list]
 +
*[http://www.ashp.org/menu/DrugShortages ASHP drug shortages list] - also includes information about discontinued drugs
 +
*[http://dailymed.nlm.nih.gov/dailymed/index.cfm DailyMed] - a comprehensive NLM portal to all FDA-approved drugs
 +
*[http://www.accessdata.fda.gov/scripts/cder/drugsatfda/ Drugs@FDA] - the main portal into the FDA drug database
 +
*[http://www.cancer.gov/drugdictionary The NCI Drug Dictionary] - an extensive resource with most antineoplastics (approved and in clinical trials) listed
 +
*[http://blogs.sciencemag.org/pipeline/ In the Pipeline] - a blog from a veteran of the pharmaceutical industry, Derek Lowe. General but much is cancer-relevant. The [http://www.pipeline.corante.com/ old home] of this blog is no longer active.
 +
*[[Steroid conversions]]
 +
*[[Vesicant & irritant chemotherapy]]
 +
*[http://www.fda.gov/Drugs/DevelopmentApprovalProcess/DevelopmentResources/DrugInteractionsLabeling/ucm093664.htm Drug Development and Drug Interactions: Table of Substrates, Inhibitors and Inducers]
 +
*[https://www.pharmgkb.org/view/dosing-guidelines.do?source=CPIC# CPIC Guidelines] The Clinical Pharmacogenetics Implementation Consortium provides guidelines for a small set of drugs with pharmacogenetically-guided dosing implications, some of which are oncologics
 +
 
 +
==References==
 +
<references />
 +
 
 +
[[Category:General reference pages]]
 +
[[Category:Clinical pharmacology]]

Revision as of 23:46, 21 June 2024

Back to Top

Guidelines

Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any guideline published 5+ years ago to be for historical purposes, only.

Other interesting and helpful links can be found by clicking the link.

Chemotherapy safety standards

Dose adjustments

Antimicrobials

Growth factors

Approved antineoplastics

This section contains anticancer drugs that have had at least one formal approval in any domain (FDA, EMA, etc). Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound. For drugs first approved within the current or prior calendar years, the date of initial approval is also provided here.

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Discontinued antineoplastics

This section contains drugs that have had at least one formal approval in any domain (FDA, EMA, etc), but are no longer on the market. Note that it is possible that these drugs continue to be available in some limited way, such as through compassionate use programs.

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Investigational antineoplastics

This list is far from exhaustive. Drugs are included here generally once there are some encouraging preliminary results. Since is it very difficult to tell when a company has stopped development on a drug, this list may also include drugs that are no longer under investigation.

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Supportive and other medications

This section contains supportive drugs that are either approved or investigational. Biosimilars are also indexed here, indented below their parent compound. Note that EMA biosimilar approvals do not include the four-letter suffix at this time, which we have added to distinguish the generic ingredient from the parent compound.

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By Category

Selecting a category here will take you to a new page listing all drugs in that category (note: drug categorization is an ongoing process so not all of these links are active or current).

Drugs in a REMS program

Cytotoxic Chemotherapy

Kinase inhibitors

Endocrine therapy

Investigational and Discontinued

Biologics

Supportive Medications

Radioactive agents

Benign Hematology Medications

Hematopoietic Growth Factors

Miscellaneous

Medications by Condition

Medications by Route of Administration

Medications by FDA Year of Approval

Interesting and Helpful Links

References

  1. ↑ Griggs JJ, Mangu PB, Anderson H, Balaban EP, Dignam JJ, Hryniuk WM, Morrison VA, Pini TM, Runowicz CD, Rosner GL, Shayne M, Sparreboom A, Sucheston LE, Lyman GH. Appropriate chemotherapy dosing for obese adult patients with cancer: american society of clinical oncology clinical practice guideline. J Clin Oncol. 2012 May 1;30(13):1553-61. Epub 2012 Apr 2. link to original article PubMed
  2. ↑ Smith TJ, Bohlke K, Lyman GH, Carson KR, Crawford J, Cross SJ, Goldberg JM, Khatcheressian JL, Leighl NB, Perkins CL, Somlo G, Wade JL, Wozniak AJ, Armitage JO. Recommendations for the Use of WBC Growth Factors: American Society of Clinical Oncology Clinical Practice Guideline Update. J Clin Oncol. 2015 Oct 1;33(28):3199-212. Epub 2015 Jul 13. link to original article PubMed
  3. ↑ Mancini R, Modlin J. Chemotherapy Administration Sequence: A Review of the Literature and Creation of a Sequencing Chart. J Hematol Oncol Pharm. 2011;1(1):17-25. link to original article
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