Difference between revisions of "Stub"
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− | Regimens that have not proven to be superior to a standard-of-care comparison and are thus unlikely to be expanded upon unless new evidence comes forward. This page is primarily to drive the [[Ontology]]. | + | <span id="BackToTop"></span> |
− | {{TOC limit|limit= | + | <div class="noprint" style="background-color:LightGray; position:fixed; bottom:2%; right:0.25%; padding-left:5px; padding-right:5px; margin: 15px; opacity:0.8; border-style: solid; border-color:DarkGray; border-width: 1px"> |
− | == | + | [[#top|Back to Top]] |
− | + | </div> | |
− | + | Regimens that have not proven to be superior to a standard-of-care comparison and are thus unlikely to be expanded upon unless new evidence comes forward. This page is primarily to drive the HemOnc [[Ontology]] and for historic interest. | |
− | + | {{TOC limit|limit=3}} | |
− | + | =Regimens composed solely of approved drugs= | |
− | + | ==CapeOx & Cediranib== | |
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Oxaliplatin (Eloxatin)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Cediranib (Recentin)]] | ||
− | == | + | ==CapeOx & Cetuximab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Oxaliplatin (Eloxatin)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Cetuximab (Erbitux)]] | ||
− | == | + | ==CapeOx & Lapatinib== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Oxaliplatin (Eloxatin)]] |
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Lapatinib (Tykerb)]] |
− | == | + | ==CapeOx & RT== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Oxaliplatin (Eloxatin)]] |
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
− | == | + | ==CapeOx & Tislelizumab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Oxaliplatin (Eloxatin)]] |
+ | ====Immunotherapy==== | ||
+ | *[[Tislelizumab (Baizean)]] | ||
− | == | + | ==CapeOx, Bevacizumab, Cetuximab== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
− | ==== | + | ====Chemotherapy==== |
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Oxaliplatin (Eloxatin)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Cetuximab (Erbitux)]] | ||
− | == | + | ==Carboplatin & Docetaxel (DCb) & Celecoxib== |
− | + | ===Regimen=== | |
− | + | ====Chemotherapy==== | |
− | + | *[[Carboplatin (Paraplatin)]] | |
− | + | *[[Docetaxel (Taxotere)]] | |
− | + | *[[Celecoxib (Celebrex)]] | |
+ | |||
+ | ==Carboplatin & Docetaxel (DCb) & Cetuximab== | ||
===Regimen=== | ===Regimen=== | ||
− | |||
− | |||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
− | *[[ | + | *[[Docetaxel (Taxotere)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Cetuximab (Erbitux)]] | ||
− | == | + | ==Carboplatin & Docetaxel (DCb) & Farletuzumab== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
+ | *[[Docetaxel (Taxotere)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Farletuzumab (MORAb-003)]] |
− | == | + | ==Carboplatin & Etoposide (CE) & Adebrelimab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | |||
− | |||
*[[Etoposide (Vepesid)]] | *[[Etoposide (Vepesid)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Adebrelimab (SHR-1316)]] | ||
− | == | + | ==Carboplatin & Gemcitabine (GCb), Atezolizumab, Bevacizumab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Gemcitabine (Gemzar)]] |
− | + | ====Immunotherapy==== | |
− | + | *[[Atezolizumab (Tecentriq)]] | |
− | == | ||
− | |||
− | |||
− | |||
− | |||
− | |||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | |||
*[[Bevacizumab (Avastin)]] | *[[Bevacizumab (Avastin)]] | ||
− | == | + | ==Carboplatin & Gemcitabine (GCb)/Erlotinib== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Erlotinib (Tarceva)]] |
− | |||
− | == | + | ==Carboplatin & Paclitaxel (CP) & Avelumab== |
− | + | ===Regimen=== | |
− | + | ====Chemotherapy==== | |
− | + | *[[Carboplatin (Paraplatin)]] | |
− | + | *[[Paclitaxel (Taxol)]] | |
− | + | ====Immunotherapy==== | |
+ | *[[Avelumab (Bavencio)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Gefitinib== | ||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
+ | *[[Paclitaxel (Taxol)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Gefitinib (Iressa)]] |
− | |||
− | == | + | ==Carboplatin & Paclitaxel (CP) & Interferon gamma-1b== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | + | ====Immunotherapy==== | |
− | *[[ | + | *[[Interferon gamma-1b (Actimmune)]] |
− | == | + | ==Carboplatin & Paclitaxel (CP), Bevacizumab, Cetuximab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Cetuximab (Erbitux)]] | ||
− | == | + | ==Carboplatin & Paclitaxel (CP), Cetuximab, RT== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Cetuximab (Erbitux)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
− | == | + | ==Carboplatin, Lenvatinib, Pemetrexed, Pembrolizumab== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
+ | *[[Pemetrexed (Alimta)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Pembrolizumab (Keytruda)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Lenvatinib (Lenvima)]] |
− | == | + | ==Carboplatin, Vindesine, RT== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
+ | *[[Vindesine (Eldisine)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Carfilzomib & Ibrutinib== | ||
+ | ===Regimen=== | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Carfilzomib (Kyprolis)]] |
+ | *[[Ibrutinib (Imbruvica)]] | ||
− | == | + | ==Chlorambucil, Cisplatin, Doxorubicin== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Chlorambucil (Leukeran)]] |
− | + | *[[Cisplatin (Platinol)]] | |
− | *[[ | + | *[[Doxorubicin (Adriamycin)]] |
− | == | + | ==Cisplatin & Docetaxel (DC) & Bevacizumab== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Docetaxel (Taxotere)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
− | == | + | ==Cisplatin & Docetaxel (DC) & Cetuximab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Docetaxel (Taxotere)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Cetuximab (Erbitux)]] | ||
− | == | + | ==Cisplatin & Etoposide (EP) & Paclitaxel== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | + | *[[Etoposide (Vepesid)]] | |
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | |||
− | * | ||
− | == | + | ==Cisplatin & Etoposide (EP) & Pravastatin== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Etoposide (Vepesid)]] |
− | + | *[[Pravastatin (Pravachol)]] | |
− | * | ||
− | == | + | ==Cisplatin & Etoposide (EP) & RT== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
− | |||
− | |||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
− | == | + | ==Cisplatin & Etoposide (EP)/Topotecan monotherapy== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Etoposide (Vepesid)]] |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
*[[Topotecan (Hycamtin)]] | *[[Topotecan (Hycamtin)]] | ||
− | == | + | ==Cisplatin & Fluorouracil (CF) & Bevacizumab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Fluorouracil (5-FU)]] |
====Targeted therapy==== | ====Targeted therapy==== | ||
*[[Bevacizumab (Avastin)]] | *[[Bevacizumab (Avastin)]] | ||
− | == | + | ==Cisplatin & Fluorouracil (CF), Interferon alfa-2b, RT== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Fluorouracil (5-FU)]] |
− | *[[ | + | ====Immunotherapy==== |
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
− | == | + | ==Cisplatin & Fluorouracil (CF), Lenvatinib, Pembrolizumab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Fluorouracil (5-FU)]] |
====Immunotherapy==== | ====Immunotherapy==== | ||
− | *[[ | + | *[[Pembrolizumab (Keytruda)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Lenvatinib (Lenvima)]] | ||
− | == | + | ==Cisplatin & Fluorouracil (CF), Pembrolizumab, Trastuzumab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Fluorouracil (5-FU)]] |
+ | ====Immunotherapy==== | ||
+ | *[[Pembrolizumab (Keytruda)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Trastuzumab (Herceptin)]] |
− | == | + | ==Cisplatin & Irinotecan (IC) & Cetuximab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Irinotecan (Camptosar)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Cetuximab (Erbitux)]] | ||
− | ==Cisplatin | + | ==Cisplatin, Nintedanib, Pemetrexed== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Pemetrexed (Alimta)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Nintedanib (Vargatef)]] | ||
− | ==Cisplatin | + | ==Cisplatin, Paclitaxel, Cetuximab, RT== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Cetuximab (Erbitux)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
− | ==Cisplatin | + | ==Cisplatin, Paclitaxel, Erlotinib, RT== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
− | ==Cisplatin, | + | ==Cisplatin, Paclitaxel, Lenvatinib, Pembrolizumab== |
− | + | ===Regimen=== | |
− | |||
− | |||
− | |||
− | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | ==== | + | ====Immunotherapy==== |
− | * | + | *[[Pembrolizumab (Keytruda)]] |
+ | ====Targeted therapy==== | ||
+ | *[[Lenvatinib (Lenvima)]] | ||
− | == | + | ==Cisplatin, Paclitaxel, Tislelizumab, RT== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | *[[ | + | ====Immunotherapy==== |
− | *[[ | + | *[[Tislelizumab (Baizean)]] |
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==3M== | ||
− | + | 3M: '''<u>M</u>'''itomycin, '''<u>M</u>'''itoxantrone, '''<u>M</u>'''ethotrexate | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Mitomycin (Mutamycin)]] |
− | *[[ | + | *[[Mitoxantrone (Novantrone)]] |
− | *[[ | + | *[[Methotrexate (MTX)]] |
− | == | + | ==4d+7== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Daunorubicin (Cerubidine)]] |
− | |||
− | |||
− | == | + | ==4i+7== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Idarubicin (Idamycin)]] |
− | ==== | + | |
− | + | ==5-FU & RT== | |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Fluorouracil (5-FU)]] |
− | + | ====Radiotherapy==== | |
− | ==== | + | *Concurrent [[External_beam_radiotherapy|radiation therapy]] |
− | *[[ | ||
− | == | + | ==5-FU, Cyclophosphamide, Dactinomycin== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cyclophosphamide (Cytoxan)]] |
− | *[[ | + | *[[Dactinomycin (Cosmegen)]] |
− | + | *[[Fluorouracil (5-FU)]] | |
− | *[[ | ||
− | == | + | ==7+2d== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Daunorubicin (Cerubidine)]] |
− | |||
− | |||
− | == | + | ==7+3a== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | |||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | |||
− | == | + | ==7+3d & Azacitidine== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Daunorubicin (Cerubidine)]] |
− | *[[ | + | *[[Azacitidine (Vidaza)]] |
− | |||
− | |||
− | == | + | ==7+3d & GM-CSF== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | ==== | + | *[[Daunorubicin (Cerubidine)]] |
− | *[[ | + | ====Growth factor therapy==== |
+ | *[[Sargramostim (Leukine)]] | ||
− | == | + | ==7+3d & Zosuquidar== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | *[[Daunorubicin (Cerubidine)]] | |
− | *[[ | + | |
+ | ==7+3i & Clofarabine== | ||
− | + | 7+3i & Clofarabine: '''<u>7</u>''' days of cytarabine, '''<u>3</u>''' days of '''<u>i</u>'''darubicin, Clofarabine | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | *[[Idarubicin (Idamycin)]] | |
− | *[[ | + | *[[Clofarabine (Clolar)]] |
+ | |||
+ | ==7+3i & Lenalidomide== | ||
− | + | 7+3i & Lenalidomide: '''<u>7</u>''' days of cytarabine, '''<u>3</u>''' days of '''<u>i</u>'''darubicin, Lenalidomide | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
+ | *[[Idarubicin (Idamycin)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Lenalidomide (Revlimid)]] |
− | == | + | ==7+4d== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | *[[Daunorubicin (Cerubidine)]] | |
− | *[[ | ||
− | == | + | ==7+4i== |
− | + | ||
− | + | 7+4i: '''<u>7</u>''' days of cytarabine, '''<u>4</u>''' days of '''<u>i</u>'''darubicin | |
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | *[[Idarubicin (Idamycin)]] | |
− | *[[ | + | |
+ | ==7+5d== | ||
− | + | 7+5d: '''<u>7</u>''' days of cytarabine, '''<u>5</u>''' days of '''<u>d</u>'''aunorubicin | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | *[[Daunorubicin (Cerubidine)]] | |
− | *[[ | ||
− | == | + | ==7+5i & Quinine== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | *[[Idarubicin (Idamycin)]] | |
− | *[[ | + | *[[Quinine (Qualaquin)]] |
− | == | + | ==10+3d== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Daunorubicin (Cerubidine)]] |
− | == | + | ==A-C== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | |||
− | == | + | ==A-CHOP-14== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Alemtuzumab (Campath)]] |
− | == | + | ==A-D== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | |||
− | == | + | ==A-D-CMF== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | *[[ | + | *[[Cyclophosphamide (Cytoxan)]] |
+ | *[[Methotrexate (MTX)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
− | == | + | ==Abiraterone & Enzalutamide== |
− | + | ||
− | + | ===Regimen=== | |
− | + | ====Endocrine therapy==== | |
− | + | *[[Abiraterone (Zytiga)]] | |
− | + | *[[Enzalutamide (Xtandi)]] | |
+ | |||
+ | ==Abiraterone & Ipatasertib== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Abiraterone (Zytiga)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Ipatasertib (GDC-0068)]] | ||
+ | |||
+ | ==Abiraterone, Radium-223, Prednisone== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Abiraterone (Zytiga)]] | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[Radium-223 (Xofigo)]] | ||
+ | |||
+ | ==ABV== | ||
+ | ABV: '''<u>A</u>'''driamycin (Doxorubicin), '''<u>B</u>'''leomycin, '''<u>V</u>'''inblastine | ||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | *[[ | + | *[[Bleomycin (Blenoxane)]] |
+ | *[[Vinblastine (Velban)]] | ||
− | == | + | ==ABVP== |
− | + | ABVP: '''<u>A</u>'''driamycin (Doxorubicin), '''<u>B</u>'''leomycin, '''<u>V</u>'''inblastine, '''<u>P</u>'''latinol (Cisplatin) | |
− | + | ===Regimen=== | |
− | + | ====Chemotherapy==== | |
− | + | *[[Doxorubicin (Adriamycin)]] | |
− | + | *[[Bleomycin (Blenoxane)]] | |
+ | *[[Vinblastine (Velban)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | |||
+ | ==AC-KP== | ||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Cyclophosphamide (Cytoxan)]] | *[[Cyclophosphamide (Cytoxan)]] | ||
− | *[[ | + | *[[Doxorubicin (Adriamycin)]] |
− | *[[ | + | ====Targeted therapy==== |
− | *[[ | + | *[[Pertuzumab (Perjeta)]] |
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Trastuzumab emtansine (Kadcyla)]] | ||
− | == | + | ==ddAC-KP== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cyclophosphamide (Cytoxan)]] |
− | *[[ | + | *[[Doxorubicin (Adriamycin)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Trastuzumab emtansine (Kadcyla)]] | ||
− | == | + | ==Acalabrutinib & Venetoclax== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Acalabrutinib (Calquence)]] |
+ | *[[Venetoclax (Venclexta)]] | ||
+ | |||
+ | ==ACP== | ||
− | + | ACP: '''<u>A</u>'''tezolizumab, '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | |||
− | |||
− | == | + | ==AD-CMF== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Doxorubicin (Adriamycin)]] |
− | *[[ | + | *[[Docetaxel (Taxotere)]] |
− | + | *[[Cyclophosphamide (Cytoxan)]] | |
− | *[[ | + | *[[Methotrexate (MTX)]] |
− | + | *[[Fluorouracil (5-FU)]] | |
− | * | + | |
+ | ==Afatinib & Vinorelbine== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Vinorelbine (Navelbine)]] | *[[Vinorelbine (Navelbine)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Afatinib (Gilotrif)]] |
− | == | + | ==A-ICE== |
− | + | ||
− | + | A-ICE: '''<u>A</u>'''TRA, '''<u>I</u>'''darubicin, '''<u>C</u>'''ytarabine, '''<u>E</u>'''toposide | |
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[All-trans retinoic acid (ATRA)]] |
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Mitoxantrone (Novantrone)]] |
+ | *[[Etoposide (Vepesid)]] | ||
− | == | + | ==Altretamine & Melphalan== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Altretamine (Hexalen)]] |
− | *[[ | + | *[[Melphalan (Alkeran)]] |
− | ==== | + | |
− | + | ==AME== | |
− | + | AME: '''<u>A</u>'''ra-C (Cytarabine), '''<u>M</u>'''itoxantrone, '''<u>E</u>'''toposide | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Mitoxantrone (Novantrone)]] |
− | *[[ | + | *[[Etoposide (Vepesid)]] |
− | ==== | + | |
− | + | ==API== | |
− | |||
− | + | API: '''<u>A</u>'''driamycin (Doxorubicin), '''<u>P</u>'''latinol (Cisplatin), '''<u>I</u>'''fosfamide | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Doxorubicin (Adriamycin)]] |
− | *[[ | + | *[[Cisplatin (Platinol)]] |
+ | *[[Ifosfamide (Ifex)]] | ||
− | == | + | ==Amrubicin & Cisplatin== |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Amrubicin (Calsed)]] |
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | |||
− | == | + | ==Amsacrine monotherapy== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Amsacrine (Amsidine)]] |
− | |||
− | |||
− | |||
− | |||
− | == | + | ==Amsacrine & Cytarabine== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Amsacrine (Amsidine)]] |
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | + | ||
+ | ==Amsacrine & IDAC== | ||
− | + | Amsacrine & IDAC: Amsacrine & '''<u>I</u>'''ntermediate '''<u>D</u>'''ose '''<u>A</u>'''ra-'''<u>C</u>''' (Cytarabine) | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Amsacrine (Amsidine)]] |
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
+ | |||
+ | ==Anastrozole and Everolimus== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Anastrozole (Arimidex)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Everolimus (Afinitor)]] |
− | == | + | ==Anastrozole and Lapatinib== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
− | ==== | + | ====Endocrine therapy==== |
− | *[[ | + | *[[Anastrozole (Arimidex)]] |
− | + | ====Targeted therapy==== | |
− | *[[ | + | *[[Lapatinib (Tykerb)]] |
− | == | + | ==Anastrozole and Tamoxifen== |
− | + | ===Regimen=== | |
− | + | ====Endocrine therapy==== | |
− | + | *[[Anastrozole (Arimidex)]] | |
− | + | *[[Tamoxifen (Nolvadex)]] | |
+ | ==Anlotinib monotherapy== | ||
===Regimen=== | ===Regimen=== | ||
− | |||
− | |||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Anlotinib (Fukewei)]] |
+ | |||
+ | ==ATRA, Cytarabine, Etoposide== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[All-trans retinoic acid (ATRA)]] | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
*[[Etoposide (Vepesid)]] | *[[Etoposide (Vepesid)]] | ||
− | == | + | ==AVML== |
− | + | AVML: '''<u>A</u>'''ra-C (Cytarabine), '''<u>V</u>'''incristine, '''<u>M</u>'''ethotrexate, '''<u>L</u>'''eucovorin | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cytarabine (Ara-C)]] |
− | *[[ | + | *[[Vincristine (Oncovin)]] |
− | *[[ | + | *[[Methotrexate (MTX)]] |
+ | ====Supportive therapy==== | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
− | == | + | ==Axitinb & Toripalimab== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
− | ==== | + | ====Immunotherapy==== |
− | *[[ | + | *[[Toripalimab (Loqtorzi)]] |
− | + | ====Targeted therapy==== | |
− | *[[ | + | *[[Axitinib (Inlyta)]] |
− | == | + | ==Azacitidine & Eltrombopag== |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Azacitidine (Vidaza)]] |
− | + | ====Growth factor therapy==== | |
− | ==== | + | *[[Eltrombopag (Promacta)]] |
− | *[[ | ||
− | == | + | ==Azacitidine & Gilteritinib== |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Azacitidine (Vidaza)]] |
− | ==== | + | ====Targeted therapy==== |
− | *[[ | + | *[[Gilteritinib (Xospata)]] |
+ | |||
+ | ==Binimetinib monotherapy== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
− | ==== | + | ====Targeted therapy==== |
− | *[[ | + | *[[Binimetinib (Mektovi)]] |
− | + | ||
− | + | ==Bortezomib & Bevacizumab== | |
− | == | + | ===Regimen=== |
− | {| class="wikitable" style=" | + | {| class="wikitable sortable" style="width: 100%; text-align:center;" |
+ | !style="width: 20%"|Study | ||
+ | !style="width: 20%"|Dates of enrollment | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Evidence|Evidence]] | ||
+ | !style="width: 20%"|Comparator | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Comparative_efficacy|Comparative Efficacy]] | ||
+ | |- | ||
+ | |[https://doi.org/10.1002/cncr.27745 White et al. 2012 (AMBER)] | ||
+ | |2007-2009 | ||
+ | |style="background-color:#1a9851"|Randomized Phase 2 (E-esc) | ||
+ | |[[Multiple_myeloma,_relapsed-refractory#Bortezomib_monotherapy|Bortezomib]] | ||
+ | |style="background-color:#ffffbf"|Did not meet primary endpoint of PFS <br>(HR 0.74, 95% CI 0.43-1.28) | ||
|- | |- | ||
− | |||
|} | |} | ||
− | + | ====Targeted therapy==== | |
+ | *[[Bortezomib (Velcade)]] | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Bortezomib & Siltuximab== | ||
+ | |||
===Regimen=== | ===Regimen=== | ||
− | ==== | + | {| class="wikitable sortable" style="width: 100%; text-align:center;" |
− | + | !style="width: 20%"|Study | |
− | + | !style="width: 20%"|Dates of enrollment | |
− | + | !style="width: 20%"|[[Levels_of_Evidence#Evidence|Evidence]] | |
− | + | !style="width: 20%"|Comparator | |
− | + | !style="width: 20%"|[[Levels_of_Evidence#Comparative_efficacy|Comparative Efficacy]] | |
− | + | |- | |
+ | |[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737504/ Orlowski et al. 2015 (CR012784)] | ||
+ | |2006-2009 | ||
+ | |style="background-color:#1a9851"|Randomized Phase 2 (E-esc) | ||
+ | |[[Multiple_myeloma,_relapsed-refractory#Bortezomib_monotherapy|Bortezomib]] | ||
+ | |style="background-color:#ffffbf"|Did not meet primary endpoint of PFS <br>(HR 0.87, 95% CI 0.65-1.16) | ||
|- | |- | ||
− | |||
|} | |} | ||
− | |||
− | |||
− | |||
− | |||
− | |||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Bortezomib (Velcade)]] |
+ | ====Immunosuppressive therapy==== | ||
+ | *[[Siltuximab (Sylvant)]] | ||
+ | |||
+ | ==BTH (Docetaxel)== | ||
− | + | BTH: '''<u>B</u>'''evacizumab, '''<u>T</u>'''axotere (Docetaxel), '''<u>H</u>'''erceptin (Trastuzumab) | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Docetaxel (Taxotere)]] |
− | *[[ | + | ====Targeted therapy==== |
− | *[[ | + | *[[Bevacizumab (Avastin)]] |
+ | *[[Trastuzumab (Herceptin)]] | ||
+ | |||
+ | ==BTOC== | ||
− | + | BTOC: '''<u>B</u>'''CNU, '''<u>T</u>'''hiotepa, '''<u>O</u>'''ncovin (Vincristine), '''<u>C</u>'''yclophosphamide | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carmustine (BCNU)]] |
− | *[[ | + | *[[Thiotepa (Thioplex)]] |
− | *[[ | + | *[[Vincristine (Oncovin)]] |
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
− | == | + | ==CAD== |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | + | CAD: '''<u>C</u>'''yclophosphamide, '''<u>A</u>'''driamycin (Doxorubicin), '''<u>D</u>'''DP (Cisplatin) | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | |||
− | |||
− | == | + | ==Capecitabine & Cisplatin (CX) & Bevacizumab== |
− | + | ||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | ====Targeted therapy==== |
− | + | *[[Bevacizumab (Avastin)]] | |
− | + | ||
+ | ==Capecitabine & Cisplatin (CX) & Ramucirumab== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | ====Targeted therapy==== |
− | + | *[[Ramucirumab (Cyramza)]] | |
+ | |||
+ | ==Capecitabine & Ruxolitinib== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | ====Targeted therapy==== |
− | + | *[[Ruxolitinib (Jakafi)]] | |
+ | |||
+ | ==Capecitabine & Sorafenib== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Sorafenib (Nexavar)]] |
+ | |||
+ | ==Capecitabine & Sunitinib== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Sunitinib (Sutent)]] |
+ | |||
+ | ==Capecitabine & Vinflunine== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | + | *[[Vinflunine (Javlor)]] | |
− | *[[ | + | |
+ | ==Capecitabine & Vinorelbine (NX)== | ||
− | + | NX: '''<u>N</u>'''avelbine (Vinorelbine) & '''<u>X</u>'''eloda (Capecitabine) | |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Vinorelbine (Navelbine)]] |
− | + | ||
+ | ==Capecitabine, Cisplatin, Cetuximab, RT== | ||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Cetuximab (Erbitux)]] |
− | ==== | + | ====Radiotherapy==== |
− | *[[ | + | *Concurrent [[External_beam_radiotherapy|radiation therapy]] |
− | + | ||
− | + | ==Capecitabine, Erlotinib, RT== | |
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | ====Targeted therapy==== |
− | *[[ | + | *[[Erlotinib (Tarceva)]] |
+ | ====Radiotherapy==== | ||
+ | *Concurrent [[External_beam_radiotherapy|radiation therapy]] | ||
+ | ==Capivasertib & Fulvestrant== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Fulvestrant (Faslodex)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Capivasertib (Truqap)]] | ||
+ | ==CarboMIP== | ||
− | + | CarboMIP: '''<u>Carbo</u>'''platin, '''<u>M</u>'''itomycin, '''<u>I</u>'''fosfamide, '''<u>P</u>'''latinol (Cisplatin) | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
− | *[[ | + | *[[Mitomycin (Mutamycin)]] |
+ | *[[Ifosfamide (Ifex)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | |||
+ | ==Carboplatin & Epirubicin== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
− | + | *[[Epirubicin (Ellence)]] | |
− | *[[ | ||
− | == | + | ==Carboplatin & Gemcitabine (GCb) & Gefitinib== |
− | + | ===Regimen=== | |
− | |||
− | |||
− | |||
− | |||
− | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Gefitinib (Iressa)]] |
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Bexarotene== | ||
− | + | CP & Bexarotene: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Bexarotene | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
*[[Paclitaxel (Taxol)]] | *[[Paclitaxel (Taxol)]] | ||
− | *[[ | + | ====Targeted therapy==== |
− | + | *[[Bexarotene (Targretin)]] | |
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Cetuximab== | ||
− | + | CP & Cetuximab: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Cetuximab | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Cetuximab (Erbitux)]] |
− | + | ||
+ | ==Carboplatin & Paclitaxel (CP) & Erlotinib== | ||
− | + | CP & Erlotinib: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Erlotinib | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Erlotinib (Tarceva)]] |
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Pegylated liposomal doxorubicin== | ||
− | + | CP & PLD: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, '''<u>P</u>'''egylated '''<u>L</u>'''iposomal '''<u>D</u>'''oxorubicin | |
− | + | <br>TC & PLD: '''<u>T</u>'''axol (Paclitaxel), '''<u>C</u>'''arboplatin, '''<u>P</u>'''egylated '''<u>L</u>'''iposomal '''<u>D</u>'''oxorubicin | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Paclitaxel (Taxol)]] | *[[Paclitaxel (Taxol)]] | ||
− | |||
*[[Carboplatin (Paraplatin)]] | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Pegylated liposomal doxorubicin (Doxil)]] | ||
− | == | + | ==Carboplatin & Paclitaxel (CP) & Sorafenib== |
− | + | ||
− | + | CP & Sorafenib: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Sorafenib | |
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
====Targeted therapy==== | ====Targeted therapy==== | ||
− | *[[ | + | *[[Sorafenib (Nexavar)]] |
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Topotecan== | ||
− | + | TC & Topotecan: '''<u>T</u>'''axol (Paclitaxel), '''<u>C</u>'''arboplatin, Topotecan | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Paclitaxel (Taxol)]] |
− | + | *[[Carboplatin (Paraplatin)]] | |
− | *[[ | + | *[[Topotecan (Hycamtin)]] |
− | *[[ | + | |
+ | ==Carboplatin & Topotecan== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | + | *[[Topotecan (Hycamtin)]] | |
− | *[[ | + | |
+ | ==CBM== | ||
− | + | CBM: '''<u>C</u>'''apecitabine, '''<u>B</u>'''evacizumab, '''<u>M</u>'''itomycin | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Capecitabine (Xeloda)]] |
− | *[[ | + | *[[Mitomycin (Mutamycin)]] |
− | *[[ | + | ====Targeted therapy==== |
− | + | *[[Bevacizumab (Avastin)]] | |
+ | |||
+ | ==CCG== | ||
− | + | CCG: '''<u>C</u>'''isplatin, '''<u>C</u>'''arboplatin, '''<u>G</u>'''emcitabine | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | + | *[[Gemcitabine (Gemzar)]] | |
− | *[[ | + | |
+ | ==Carboplatin & Etoposide (CE) & Ipilimumab== | ||
− | + | CE & Ipilimumab: '''<u>C</u>'''arboplatin, '''<u>E</u>'''toposide, Ipilimumab | |
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Carboplatin (Paraplatin)]] |
− | *[[ | + | *[[Etoposide (Vepesid)]] |
− | *[[ | + | ====Immunotherapy==== |
+ | *[[Ipilimumab (Yervoy)]] | ||
− | == | + | ==Carboplatin & Etoposide (CE) & Thalidomide== |
− | + | ||
− | + | CE & Thalidomide: '''<u>C</u>'''arboplatin, '''<u>E</u>'''toposide, Thalidomide | |
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Thalidomide (Thalomid)]] | ||
+ | |||
+ | ==ChlVPP/EVA== | ||
+ | ChlVPP/EVA: '''<u>Chl</u>'''orambucil, '''<u>V</u>'''inblastine, '''<u>P</u>'''rocarbazine, '''<u>P</u>'''rednisone alternating with '''<u>E</u>'''toposide, '''<u>V</u>'''incristine, '''<u>A</u>'''driamycin (Doxorubicin) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy, ChlVPP portion==== | ||
+ | *[[Chlorambucil (Leukeran)]] | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | ====Glucocorticoid therapy, ChlVPP portion==== | ||
+ | *[[Prednisolone (Millipred)]] | ||
+ | ====Chemotherapy, EVA portion==== | ||
+ | *[[Etoposide (Vepesid)]] | ||
*[[Vincristine (Oncovin)]] | *[[Vincristine (Oncovin)]] | ||
*[[Doxorubicin (Adriamycin)]] | *[[Doxorubicin (Adriamycin)]] | ||
− | |||
− | |||
− | |||
− | |||
− | == | + | ==CIB== |
− | + | ||
− | + | CIB: '''<u>C</u>'''isplatin, '''<u>I</u>'''fosfamide, '''<u>B</u>'''leomycin | |
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
+ | *[[Ifosfamide (Ifex)]] | ||
*[[Bleomycin (Blenoxane)]] | *[[Bleomycin (Blenoxane)]] | ||
− | |||
− | == | + | ==Cisplatin & Gemcitabine (GC) & Erlotinib== |
− | + | GC & Erlotinib: '''<u>G</u>'''emcitabine, '''<u>C</u>'''isplatin, Erlotinib | |
− | + | ===Regimen=== | |
− | + | ====Chemotherapy==== | |
− | + | *[[Cisplatin (Platinol)]] | |
− | + | *[[Gemcitabine (Gemzar)]] | |
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | |||
+ | ==Cisplatin & Gemcitabine (GC) & Gefitinib== | ||
+ | GC & Gefitinib: '''<u>G</u>'''emcitabine, '''<u>C</u>'''isplatin, Gefitinib | ||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Gemcitabine (Gemzar)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Gefitinib (Iressa)]] | ||
− | == | + | ==Cisplatin & Gemcitabine (GC) & Nadroparin== |
− | + | GC & Nadroparin: '''<u>G</u>'''emcitabine, '''<u>C</u>'''isplatin, Nadroparin | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Gemcitabine (Gemzar)]] |
− | *[[ | + | ====Anticoagulation==== |
+ | *[[Nadroparin (Fraxiparine)]] | ||
− | == | + | ==Cisplatin & Gemcitabine (GC) & Sorafenib== |
− | + | GC & Sorafenib: '''<u>G</u>'''emcitabine, '''<u>C</u>'''isplatin, Sorafenib | |
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | ==== | + | *[[Gemcitabine (Gemzar)]] |
− | *[[ | + | ====Targeted therapy==== |
+ | *[[Sorafenib (Nexavar)]] | ||
− | == | + | ==Cisplatin & Gemcitabine (GC) & Tislelizumab== |
− | + | GC & Tislelizumab: '''<u>G</u>'''emcitabine, '''<u>C</u>'''isplatin, Tislelizumab | |
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | *[[Gemcitabine (Gemzar)]] |
− | *[[ | + | ====Immunotherapy==== |
+ | *[[Tislelizumab (Baizean)]] | ||
+ | |||
+ | ==Cisplatin & Methotrexate== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
− | |||
*[[Cisplatin (Platinol)]] | *[[Cisplatin (Platinol)]] | ||
− | *[[ | + | *[[Methotrexate (MTX)]] |
+ | |||
+ | ==Cisplatin & Treosulfan== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Treosulfan (Ovastat)]] | ||
+ | |||
+ | ==Cisplatin & Vincristine== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | |||
+ | ==Cisplatin, Avelumab, RT== | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
===Regimen=== | ===Regimen=== | ||
− | ====Targeted therapy==== | + | ====Chemotherapy==== |
− | *[[ | + | *[[Cisplatin (Platinol)]] |
− | *[[ | + | ====Immunotherapy==== |
− | *[[ | + | *[[Avelumab (Bavencio)]] |
+ | ====Radiotherapy==== | ||
+ | *Concurrent [[External_beam_radiotherapy|radiation therapy]] | ||
+ | |||
+ | ==Cisplatin, Pemetrexed, Gefitinib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | {| class="wikitable sortable" style="width: 100%; text-align:center;" | ||
+ | ! style="width: 20%" |Study | ||
+ | ! style="width: 20%" |Dates of enrollment | ||
+ | ! style="width: 20%" |[[Levels_of_Evidence#Evidence|Evidence]] | ||
+ | ! style="width: 20%" |Comparator | ||
+ | ! style="width: 20%" |[[Levels_of_Evidence#Comparative_efficacy|Comparative Efficacy]] | ||
+ | |- | ||
+ | |[https://doi.org/10.1016/S1470-2045(15)00121-7 Soria et al. 2015 (IMPRESS)] | ||
+ | |2012-2013 | ||
+ | | style="background-color:#1a9851" |Phase 3 (E-esc) | ||
+ | |[[Non-small_cell_lung_cancer,_EGFR-mutated#Cisplatin_.26_Pemetrexed_3|Cisplatin & Pemetrexed]] | ||
+ | | style="background-color:#ffffbf" |Did not meet primary endpoint of PFS<br>Median PFS: 5.4 vs 5.4 mo<br>(HR 0.86, 95% CI 0.65-1.13) | ||
+ | |- | ||
+ | |} | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Pemetrexed (Alimta)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Gefitinib (Iressa)]] | ||
+ | |||
+ | ==Cisplatin, Pemetrexed, RT== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Pemetrexed (Alimta)]] | ||
+ | ====Radiotherapy==== | ||
+ | *Concurrent [[External_beam_radiotherapy|radiation therapy]] | ||
+ | |||
+ | ==CODE== | ||
+ | |||
+ | CODE: '''<u>C</u>'''isplatin, '''<u>O</u>'''ncovin (Vincristine), '''<u>D</u>'''oxorubicin, '''<u>E</u>'''toposide | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==COPPEBVCAD== | ||
+ | COPPEBVCAD: '''<u>C</u>'''yclophosphamide, '''<u>O</u>'''ncovin (Vincristine), '''<u>P</u>'''rocarbazine, '''<u>P</u>'''rednisone, '''<u>E</u>'''pirubicin, '''<u>B</u>'''leomycin, '''<u>V</u>'''inblastine, '''<u>C</u>'''CNU (Lomustine), '''<u>A</u>'''lkeran (Melphalan), '''<u>D</u>'''VA (Vindesine) | ||
+ | ===Regimen=== | ||
====Chemotherapy==== | ====Chemotherapy==== | ||
*[[Cyclophosphamide (Cytoxan)]] | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Bleomycin (Blenoxane)]] | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | *[[Lomustine (CCNU)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==CYVADIC== | ||
+ | |||
+ | CYVADIC: '''<u>CY</u>'''clophosphamide, '''<u>V</u>'''incristine, '''<u>AD</u>'''riamycin (Doxorubicin), '''<u>I</u>'''midazole '''<u>C</u>'''arboxamide (Dacarbazine) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | ==Dacarbazine & Dactinomycin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Dactinomycin (Cosmegen)]] | ||
+ | |||
+ | ==Dacarbazine & Fotemustine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Fotemustine (Muphoran)]] | ||
+ | |||
+ | ==Dacarbazine & Interferon alfa-2b== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | |||
+ | ==Dacarbazine & Selumetinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Selumetinib (Koselugo)]] | ||
+ | |||
+ | ==Dacarbazine & Vindesine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | |||
+ | ==Dacarbazine, Fluorouracil, Semustine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | |||
+ | ==Dacarbazine, Fluorouracil, Semustine, Vincristine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | |||
+ | ==Dacarbazine, Fotemustine, Interferon alfa-2b== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Fotemustine (Muphoran)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | |||
+ | ==Dacarbazine, Interferon alfa-2b, Tamoxifen== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | |||
+ | ==Dactinomycin, Doxorubicin, Vincristine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dactinomycin (Cosmegen)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | ==DBCT== | ||
+ | |||
+ | DBCT: '''<u>D</u>'''acarbazine, '''<u>B</u>'''CNU (Carmustine), '''<u>C</u>'''isplatin, '''<u>T</u>'''amoxifen | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Carmustine (BCNU)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | ==Docetaxel & Erlotinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | |||
+ | ==Docetaxel & Fluorouracil== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ==Docetaxel & Gefitinib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Gefitinib (Iressa)]] | ||
+ | |||
+ | ==Docetaxel & Lapatinib (TL)== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | |||
+ | ==Docetaxel & Leuprolide== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Leuprolide (Lupron)]] | ||
+ | |||
+ | ==Docetaxel & Pertuzumab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | |||
+ | ==Docetaxel & Selumetinib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Selumetinib (Koselugo)]] | ||
+ | |||
+ | ==Docetaxel & Sunitinib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sunitinib (Sutent)]] | ||
+ | |||
+ | ==Docetaxel & Ziv-aflibercept== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Ziv-aflibercept (Zaltrap)]] | ||
+ | |||
+ | ==Docetaxel, Lenalidomide, Prednisone== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lenalidomide (Revlimid)]] | ||
+ | |||
+ | ==Docetaxel, Prednisone, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Doxorubicin & Etoposide== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==Doxorubicin & Paclitaxel== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | |||
+ | ==Doxorubicin & Sorafenib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==Doxorubicin & Streptozocin== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Streptozocin (Zanosar)]] | ||
+ | |||
+ | ==Doxorubicin & Vinblastine (AV)== | ||
+ | AV: '''<u>A</u>'''driamycin (Doxorubicin) & '''<u>V</u>'''inblastine | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | |||
+ | ==Doxorubicin & Vinorelbine== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | |||
+ | ==EAP== | ||
+ | |||
+ | EAP: '''<u>E</u>'''toposide, '''<u>A</u>'''driamycin (Doxorubicin), '''<u>P</u>'''latinol (Cisplatin) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | |||
+ | ==ECVBP== | ||
+ | |||
+ | ECVBP: '''<u>E</u>'''pirubicin, '''<u>C</u>'''yclophosphamide, '''<u>V</u>'''indesine, '''<u>B</u>'''leomycin, '''<u>P</u>'''rednisone | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | *[[Bleomycin (Blenoxane)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==ECX & Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==EC-KP== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Trastuzumab emtansine (Kadcyla)]] | ||
+ | |||
+ | ==ddEC-KP== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Trastuzumab emtansine (Kadcyla)]] | ||
+ | |||
+ | ==EC-TL (Docetaxel)== | ||
+ | EC-TL: '''<u>E</u>'''pirubicin & '''<u>C</u>'''yclophosphamide, followed by '''<u>T</u>'''axotere (Docetaxel) & '''<u>L</u>'''apatinib | ||
+ | <br>EC-DL: '''<u>E</u>'''pirubicin & '''<u>C</u>'''yclophosphamide, followed by '''<u>D</u>'''ocetaxel & '''<u>L</u>'''apatinib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy, EC portion==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | ====Chemotherapy, TL portion==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy, TL portion==== | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | |||
+ | ==ELF== | ||
+ | |||
+ | ELF: '''<u>E</u>'''toposide, '''<u>L</u>'''eucovorin, 5-'''<u>F</u>'''U (Fluorouracil) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | |||
+ | ==ELFE== | ||
+ | |||
+ | ELFE: '''<u>E</u>'''toposide, '''<u>L</u>'''eucovorin, 5-'''<u>F</u>'''U (Fluorouracil), '''<u>E</u>'''pirubicin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | |||
+ | ==Encorafenib monotherapy== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Encorafenib (Braftovi)]] | ||
+ | |||
+ | ==EP & Ipilimumab== | ||
+ | |||
+ | EP & Ipilimumab: '''<u>E</u>'''toposide, '''<u>P</u>'''latinol (Cisplatin), Ipilimumab | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Ipilimumab (Yervoy)]] | ||
+ | |||
+ | ==EP, Tamoxifen, RT== | ||
+ | |||
+ | EP, Tamoxifen, RT: '''<u>E</u>'''toposide, '''<u>P</u>'''latinol (Cisplatin), Tamoxifen, '''<u>R</u>'''adiation '''<u>T</u>'''herapy | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | ====Radiotherapy==== | ||
+ | *Concurrent [[External_beam_radiotherapy|thoracic radiation therapy]] | ||
+ | |||
+ | ==Erlotinib & Sorafenib== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==Erlotinib & Sunitinib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Sunitinib (Sutent)]] | ||
+ | |||
+ | ==Erlotinib, Bevacizumab, Panitumumab== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Panitumumab (Vectibix)]] | ||
+ | |||
+ | ==Erlotinib, Gemcitabine, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Everolimus & Letrozole== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Letrozole (Femara)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | |||
+ | ==Everolimus & Paclitaxel== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | |||
+ | ==Everolimus & Sorafenib== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==Everolimus & Vinorelbine== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | |||
+ | ==Exemestane & Lapatinib== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Exemestane (Aromasin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | |||
+ | ==Exemestane & Palbociclib== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Exemestane (Aromasin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Palbociclib (Ibrance)]] | ||
+ | |||
+ | ==E-GEMOX== | ||
+ | |||
+ | E-GEMOX: '''<u>E</u>'''rlotinib, '''<u>GEM</u>'''citabine, '''<u>OX</u>'''aliplatin | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | |||
+ | ==FAP== | ||
+ | |||
+ | FAP: '''<u>F</u>'''luorouracil, '''<u>A</u>'''lfa interferon, '''<u>P</u>'''latinol (Cisplatin) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | |||
+ | ==FEC & HP== | ||
+ | |||
+ | FEC & HP: '''<u>F</u>'''luorouracil, '''<u>E</u>'''pirubicin, '''<u>C</u>'''yclophosphamide, '''<u>H</u>'''erceptin (Trastuzumab), '''<u>P</u>'''ertuzumab | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trastuzumab (Herceptin)]] | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | |||
+ | ==ddFEC== | ||
+ | |||
+ | ddFEC: '''<u>d</u>'''ose-'''<u>d</u>'''ense '''<u>F</u>'''luorouracil, '''<u>E</u>'''pirubicin, '''<u>C</u>'''yclophosphamide | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | ====Supportive therapy==== | ||
+ | *[[:Category:Granulocyte_colony-stimulating_factors|G-CSF]] | ||
+ | |||
+ | ==FLA== | ||
+ | |||
+ | FLA: '''<u>FL</u>'''udarabine & '''<u>A</u>'''ra-C (Cytarabine) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fludarabine (Fludara)]] | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | |||
+ | ==FLAG-Ida & GO== | ||
+ | |||
+ | FLAG-Ida & GO: '''<u>FL</u>'''udarabine, '''<u>A</u>'''ra-C (Cytarabine), '''<u>G</u>'''-CSF (Lenograstim), '''<u>Ida</u>'''rubicin, '''<u>G</u>'''emtuzumab '''<u>O</u>'''zogamicin | ||
+ | ===Regimen {{#subobject:44e85e|Variant=1}}=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fludarabine (Fludara)]] 30 mg/m<sup>2</sup> IV once per day on days 2 to 6 | ||
+ | *[[Cytarabine (Ara-C)]] 2000 mg/m<sup>2</sup> IV over 4 hours once per day on days 2 to 6, '''given 4 hours after fludarabine''' | ||
+ | *[[Idarubicin (Idamycin)]] 8 mg/m<sup>2</sup> IV once per day on days 4 to 6 | ||
+ | |||
+ | ====Growth factor therapy==== | ||
+ | *[[Lenograstim (Granocyte)]] | ||
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Gemtuzumab ozogamicin (Mylotarg)]] | ||
+ | |||
+ | ==FLAI== | ||
+ | |||
+ | FLAI: '''<u>FL</u>'''udarabine, '''<u>A</u>'''ra-C (Cytarabine), '''<u>I</u>'''darubicin | ||
+ | <br>FIA: '''<u>F</u>'''ludarabine, '''<u>I</u>'''darubicin, '''<u>A</u>'''ra-C (Cytarabine) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fludarabine (Fludara)]] | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Idarubicin (Idamycin)]] | ||
+ | |||
+ | ==FOLF-CB== | ||
+ | |||
+ | FOLF-CB: '''<u>FOL</u>'''inic acid (Leucovorin), '''<u>F</u>'''luorouracil, '''<u>C</u>'''etuximab, '''<u>B</u>'''evacizumab | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Cetuximab (Erbitux)]] | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==FOLFIRI & Regorafenib== | ||
+ | |||
+ | FOLFIRI & Regorafenib: '''<u>FOL</u>'''inic acid (Leucovorin), '''<u>F</u>'''luorouracil, '''<u>IRI</u>'''notecan, Regorafenib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Regorafenib (Stivarga)]] | ||
+ | |||
+ | ==FOLFIRI & Simvastatin== | ||
+ | |||
+ | FOLFIRI & Simvastatin: '''<u>FOL</u>'''inic acid (Leucovorin), '''<u>F</u>'''luorouracil, '''<u>IRI</u>'''notecan, Simvastatin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Simvastatin (Zocor)]] | ||
+ | |||
+ | ==FOLFIRI & Sunitinib== | ||
+ | |||
+ | FOLFIRI & Sunitinib: '''<u>FOL</u>'''inic acid (Leucovorin), '''<u>F</u>'''luorouracil, '''<u>IRI</u>'''notecan, Sunitinib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sunitinib (Sutent)]] | ||
+ | |||
+ | ==FULV & Cisplatin== | ||
+ | FULV & Cisplatin: 5-'''<u>FU</u>''', '''<u>L</u>'''euco'''<u>V</u>'''orin, Cisplatin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | |||
+ | ==FULV & Edrecolomab== | ||
+ | FULV & Edrecolomab: 5-'''<u>FU</u>''', '''<u>L</u>'''euco'''<u>V</u>'''orin, Edrecolomab | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Edrecolomab (Panorex)]] | ||
+ | |||
+ | ==FULV & Interferon alfa-2a== | ||
+ | FULV & Interferon alfa-2a: 5-'''<u>FU</u>''', '''<u>L</u>'''euco'''<u>V</u>'''orin, Interferon alfa-2a | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2a (Roferon-A)]] | ||
+ | |||
+ | ==FULV & Interferon alfa-2b== | ||
+ | FULV & Interferon alfa-2b: 5-'''<u>FU</u>''', '''<u>L</u>'''euco'''<u>V</u>'''orin, Interferon alfa-2b | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | |||
+ | ==FULV & Interferon alfa-2c== | ||
+ | FULV & Interferon alfa-2c: 5-'''<u>FU</u>''', '''<u>L</u>'''euco'''<u>V</u>'''orin, Interferon alfa-2c | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2c (Berofor)]] | ||
+ | |||
+ | ==FULV & Trimetrexate== | ||
+ | |||
+ | FULV & Trimetrexate: 5-'''<u>FU</u>''', '''<u>L</u>'''euco'''<u>V</u>'''orin, Trimetrexate | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Trimetrexate (Neutrexin)]] | ||
+ | |||
+ | ==GVP== | ||
+ | |||
+ | GVP: '''<u>G</u>'''emcitabine, '''<u>V</u>'''inorelbine, '''<u>P</u>'''latinol (Cisplatin) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | |||
+ | ==ICE, ATRA, GO== | ||
+ | |||
+ | ICE, ATRA, GO: '''<u>I</u>'''darubicin, '''<u>C</u>'''ytarabine, '''<u>E</u>'''toposide, '''<u>A</u>'''ll-'''<u>T</u>'''rans '''<u>R</u>'''etinoic '''<u>A</u>'''cid, '''<u>G</u>'''emtuzumab '''<u>O</u>'''zogamicin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Idarubicin (Idamycin)]] | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[All-trans retinoic acid (ATRA)]] | ||
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Gemtuzumab ozogamicin (Mylotarg)]] | ||
+ | |||
+ | ==Ixabepilone & Bevacizumab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Ixabepilone (Ixempra)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==ME== | ||
+ | |||
+ | ME: '''<u>M</u>'''itoxantrone & '''<u>E</u>'''toposide | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==MEV== | ||
+ | |||
+ | MEV: '''<u>M</u>'''itomycin, '''<u>E</u>'''toposide, '''<u>V</u>'''indesine | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitomycin (Mutamycin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | |||
+ | ==MFL== | ||
+ | |||
+ | MFL: '''<u>M</u>'''ethyl-lomustine (MeCCNU), 5-'''<u>F</u>'''U, '''<u>L</u>'''eucovorin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | |||
+ | ==MFT== | ||
+ | |||
+ | MFL: '''<u>M</u>'''ethotrexate, 5-'''<u>F</u>'''U, '''<u>T</u>'''amoxifen | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Methotrexate (MTX)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | |||
+ | ==Mitoxantrone & Hydrocortisone== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Hydrocortisone (Cortef)]] | ||
+ | |||
+ | ==MMF== | ||
+ | |||
+ | MMF: '''<u>M</u>'''ethyl-lomustine (MeCCNU), '''<u>M</u>'''itomycin, 5-'''<u>F</u>'''U | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | *[[Mitomycin (Mutamycin)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | |||
+ | ==MOPPEBVCAD== | ||
+ | MOPPEBVCAD: '''<u>M</u>'''echlorethamine, '''<u>O</u>'''ncovin (Vincristine), '''<u>P</u>'''rocarbazine, '''<u>P</u>'''rednisone, '''<u>E</u>'''pirubicin, '''<u>B</u>'''leomycin, '''<u>V</u>'''inblastine, '''<u>C</u>'''CNU (Lomustine), '''<u>A</u>'''driamycin (Doxorubicin), '''<u>D</u>'''VA (Vindesine) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mechlorethamine (Mustargen)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Bleomycin (Blenoxane)]] | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | *[[Lomustine (CCNU)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==MPP== | ||
+ | |||
+ | MPP: '''<u>M</u>'''elphalan, '''<u>P</u>'''rednisone, '''<u>P</u>'''rocarbazine | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==MTP== | ||
+ | |||
+ | MTP: '''<u>M</u>'''yocet (Non-pegylated liposomal doxorubicin), '''<u>T</u>'''rastuzumab, '''<u>P</u>'''aclitaxel | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Non-pegylated liposomal doxorubicin (Myocet)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trastuzumab (Herceptin)]] | ||
+ | |||
+ | ==MVC== | ||
+ | |||
+ | MVC: '''<u>M</u>'''itomycin, '''<u>V</u>'''indesine, '''<u>C</u>'''arboplatin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitomycin (Mutamycin)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | |||
+ | ==NIP== | ||
+ | |||
+ | NIP: '''<u>N</u>'''avelbine (Vinorelbine), '''<u>I</u>'''fosfamide, '''<u>P</u>'''latinol (Cisplatin) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | *[[Ifosfamide (Ifex)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ==Neratinib & Paclitaxel== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Neratinib (Nerlynx)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | |||
+ | ==PD & Pembrolizumab== | ||
+ | |||
+ | PD & Pembrolizumab: '''<u>P</u>'''omalidomide, '''<u>D</u>'''examethasone, Pembrolizumab | ||
+ | ===Regimen=== | ||
+ | {| class="wikitable sortable" style="width: 100%; text-align:center;" | ||
+ | !style="width: 20%"|Study | ||
+ | !style="width: 20%"|Dates of enrollment | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Evidence|Evidence]] | ||
+ | !style="width: 20%"|Comparator | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Comparative_efficacy|Comparative Efficacy]] | ||
+ | |- | ||
+ | |[https://doi.org/10.1016/S2352-3026(19)30110-3 Mateos et al. 2019 (KEYNOTE-183)] | ||
+ | |2016-2017 | ||
+ | |style="background-color:#1a9851"|Phase 3 (E-esc) | ||
+ | |[[Multiple_myeloma,_relapsed-refractory#Pomalidomide_.26_Dexamethasone_.28Pd.29|PD]] | ||
+ | | style="background-color:#fc8d59" |Seems to have inferior PFS <br>(HR 1.53, 95% CI 1.05-2.22) | ||
+ | |- | ||
+ | |} | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pomalidomide (Pomalyst)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Dexamethasone (Decadron)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Pembrolizumab (Keytruda)]] | ||
+ | |||
+ | ==PEI== | ||
+ | |||
+ | PEI: '''<u>P</u>'''latinol (Cisplatin), '''<u>E</u>'''toposide, '''<u>I</u>'''fosfamide | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Ifosfamide (Ifex)]] | ||
+ | |||
+ | ==PELF== | ||
+ | |||
+ | PELF: '''<u>P</u>'''latinol (Cisplatin), '''<u>E</u>'''pirubicin, '''<u>L</u>'''eucovorin, 5-'''<u>F</u>'''U | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | |||
+ | ==PGT== | ||
+ | |||
+ | PGT: '''<u>P</u>'''latinol (Cisplatin), '''<u>G</u>'''emcitabine, '''<u>T</u>'''axol (Paclitaxel) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | |||
+ | ==PGV== | ||
+ | |||
+ | PGV: '''<u>P</u>'''latinol (Cisplatin), '''<u>G</u>'''emcitabine, '''<u>V</u>'''inorelbine | ||
+ | <br>CGV: '''<u>C</u>'''isplatin, '''<u>G</u>'''emcitabine, '''<u>V</u>'''inorelbine | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | |||
+ | ==Pemetrexed & Cetuximab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Pemetrexed (Alimta)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Cetuximab (Erbitux)]] | ||
+ | |||
+ | ==Pemetrexed & Vandetanib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Pemetrexed (Alimta)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Vandetanib (Caprelsa)]] | ||
+ | |||
+ | ==Pixantrone & Rituximab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Pixantrone (Pixuvri)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Rituximab (Rituxan)]] | ||
+ | |||
+ | ==PVI== | ||
+ | |||
+ | PVI: '''<u>P</u>'''latinol (Cisplatin), '''<u>V</u>'''indesine, '''<u>I</u>'''fosfamide | ||
+ | <br>VIP: '''<u>V</u>'''indesine, '''<u>I</u>'''fosfamide, '''<u>P</u>'''latinol (Cisplatin) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | *[[Ifosfamide (Ifex)]] | ||
+ | |||
+ | ==R-BEACOPP== | ||
+ | R-BEACOPP: '''<u>R</u>'''ituximab, '''<u>B</u>'''leomycin, '''<u>E</u>'''toposide, '''<u>A</u>'''driamycin (Doxorubicin), '''<u>C</u>'''yclophosphamide, '''<u>O</u>'''ncovin (Vincristine), '''<u>P</u>'''rocarbazine, '''<u>P</u>'''rednisone | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Rituximab (Rituxan)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Bleomycin (Blenoxane)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==R-MegaCHOEP== | ||
+ | |||
+ | R-MegaCHOEP: '''<u>R</u>'''ituximab, high-dose ('''<u>Mega</u>''') '''<u>C</u>'''yclophosphamide, '''<u>H</u>'''ydroxydaunorubicin (Doxorubicin), '''<u>O</u>'''ncovin (Vincristine), '''<u>E</u>'''toposide, '''<u>P</u>'''rednisone | ||
+ | ====Targeted therapy==== | ||
+ | *[[Rituximab (Rituxan)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==Realgar-Indigo naturalis formulation monotherapy== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Realgar-Indigo naturalis formulation]] | ||
+ | |||
+ | ==TCG== | ||
+ | |||
+ | TCG: '''<u>T</u>'''axol (Paclitaxel), '''<u>C</u>'''arboplatin, '''<u>G</u>'''emcitabine | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | |||
+ | ==TCHL (Docetaxel)== | ||
+ | |||
+ | TCHL: '''<u>T</u>'''axotere (Docetaxel), '''<u>C</u>'''arboplatin, '''<u>H</u>'''erceptin (Trastuzumab), '''<u>L</u>'''apatinib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trastuzumab (Herceptin)]] | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | |||
+ | ==TCL (Docetaxel)== | ||
+ | |||
+ | TCL: '''<u>T</u>'''axotere (Docetaxel), '''<u>C</u>'''arboplatin, '''<u>L</u>'''apatinib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | |||
+ | ==TEC== | ||
+ | |||
+ | TEC: '''<u>T</u>'''axol (Paclitaxel), '''<u>E</u>'''pirubicin, '''<u>C</u>'''arboplatin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | |||
+ | ==Paclitaxel & Trastuzumab (TH) & Everolimus {{#subobject:aa22dd|Regimen=1}}== | ||
+ | |||
+ | TH & Everolimus: '''<u>T</u>'''axol (Paclitaxel), '''<u>H</u>'''erceptin (Trastuzumab), Everolimus | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trastuzumab (Herceptin)]] | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | |||
+ | ==TPCV== | ||
+ | |||
+ | TPCV: '''<u>T</u>'''hioguanine, '''<u>P</u>'''rocarbazine, '''<u>C</u>'''CNU, '''<u>V</u>'''incristine | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Thioguanine (Tabloid)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | *[[Lomustine (CCNU)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | |||
+ | ==VADx== | ||
+ | |||
+ | VADx: '''<u>V</u>'''incristine, '''<u>A</u>'''ra-C (Cytarabine), '''<u>D</u>'''e'''<u>x</u>'''amethasone | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Dexamethasone (Decadron)]] | ||
+ | |||
+ | ==VAPEC-B== | ||
+ | |||
+ | VAPEC-B: '''<u>V</u>'''incristine, '''<u>A</u>'''driamycin (Doxorubicin), '''<u>P</u>'''rednisolone, '''<u>E</u>'''toposide, '''<u>C</u>'''yclophosphamide, '''<u>B</u>'''leomycin | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Bleomycin (Blenoxane)]] | ||
+ | |||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisolone (Millipred)]] | ||
+ | |||
+ | ==VBM (Vinblastine)== | ||
+ | |||
+ | VBM: '''<u>V</u>'''inblastine, '''<u>B</u>'''leomycin, '''<u>M</u>'''ethotrexate | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | *[[Bleomycin (Blenoxane)]] | ||
+ | *[[Methotrexate (MTX)]] | ||
+ | |||
+ | ==VCE== | ||
+ | |||
+ | VCE: '''<u>V</u>'''incristine, '''<u>C</u>'''arboplatin, '''<u>E</u>'''toposide | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==Vinorelbine & Hydrocortisone== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Hydrocortisone (Cortef)]] | ||
+ | |||
+ | ==VNC== | ||
+ | |||
+ | VNC: '''<u>V</u>'''incristine, '''<u>N</u>'''ovantrone (Mitoxantrone), '''<u>C</u>'''yclophosphamide | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | |||
+ | ==VPV== | ||
+ | |||
+ | VPV: '''<u>V</u>'''inblastine, '''<u>P</u>'''latinol (Cisplatin), '''<u>V</u>'''P-16 (Etoposide) | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==VTDC== | ||
+ | |||
+ | VTDC: '''<u>V</u>'''elcade (Bortezomib), '''<u>T</u>'''halidomide, '''<u>D</u>'''examethasone, '''<u>C</u>'''yclophosphamide | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bortezomib (Velcade)]] | ||
+ | *[[Thalidomide (Thalomid)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Dexamethasone (Decadron)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | |||
+ | ==FEC-KP== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | ====Antibody-drug conjugate therapy==== | ||
+ | *[[Trastuzumab emtansine (Kadcyla)]] | ||
+ | |||
+ | ==Fluorouracil & Gemcitabine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | |||
+ | ==Fluorouracil & Interferon alfa-2a== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2a (Roferon-A)]] | ||
+ | |||
+ | ==Fluorouracil & Interferon alfa-2b== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2b (Intron-A)]] | ||
+ | |||
+ | ==Fluorouracil & Melphalan== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | |||
+ | ==Fluorouracil & Vinorelbine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | |||
+ | ==Fluorouracil, Interferon alfa-2a, Interleukin-2== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Aldesleukin (Proleukin)]] | ||
+ | *[[Interferon alfa-2a (Roferon-A)]] | ||
+ | |||
+ | ==Fluorouracil, Olaparib, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Olaparib (Lynparza)]] | ||
+ | |||
+ | ==Fluorouracil, Semustine, Vincristine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | |||
+ | ==FOLFIRI, Bevacizumab, Cetuximab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Cetuximab (Erbitux)]] | ||
+ | |||
+ | ==FULV & Interleukin-2== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Aldesleukin (Proleukin)]] | ||
+ | |||
+ | ==Fulvestrant & Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Fulvestrant (Faslodex)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Fulvestrant & Lapatinib== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Fulvestrant (Faslodex)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | |||
+ | ==Gefitinib & Simvastatin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Simvastatin (Zocor)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Gefitinib (Iressa)]] | ||
+ | |||
+ | ==Gemcitabine & Axitinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Axitinib (Inlyta)]] | ||
+ | |||
+ | ==Gemcitabine & Cetuximab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Cetuximab (Erbitux)]] | ||
+ | |||
+ | ==Gemcitabine & Cisplatin (GC) & LD IL-2== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Aldesleukin (Proleukin)]] | ||
+ | |||
+ | ==Gemcitabine & Irinotecan (IG)== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | |||
+ | ==Gemcitabine & Pemetrexed== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Pemetrexed (Alimta)]] | ||
+ | |||
+ | ==Gemcitabine & Pertuzumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | |||
+ | ==Gemcitabine & Sorafenib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==Gemcitabine & Topotecan== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Topotecan (Hycamtin)]] | ||
+ | |||
+ | ==Gemcitabine & Treosulfan== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Treosulfan (Ovastat)]] | ||
+ | |||
+ | ==Gemcitabine & Vandetanib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Vandetanib (Caprelsa)]] | ||
+ | |||
+ | ==Gemcitabine & Vinorelbine (GN)== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | |||
+ | ==Gemcitabine & Vismodegib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Vismodegib (Erivedge)]] | ||
+ | |||
+ | ==Gemcitabine & Ziv-aflibercept== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Ziv-aflibercept (Zaltrap)]] | ||
+ | |||
+ | ==Glasdegib monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Glasdegib (Daurismo)]] | ||
+ | |||
+ | ==HiDAC & Etoposide== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==HiDAC & Mitoxantrone== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | |||
+ | ==HiDAC & Quizartinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Quizartinib (Vanflyta)]] | ||
+ | |||
+ | ==HiDAC & Sorafenib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==HiDAC+3d== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Daunorubicin (Cerubidine)]] | ||
+ | |||
+ | ==HiDAC+3i== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Idarubicin (Idamycin)]] | ||
+ | |||
+ | ==Letrozole & Everolimus== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Letrozole (Femara)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | |||
+ | ==Letrozole & Temsirolimus== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Letrozole (Femara)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Temsirolimus (Torisel)]] | ||
+ | |||
+ | ==Palbociclib & Tamoxifen== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Palbociclib (Ibrance)]] | ||
+ | |||
+ | ==Pazopanib/Everolimus== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | *[[Pazopanib (Votrient)]] | ||
+ | |||
+ | ==Pravastatin & Sorafenib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Pravastatin (Pravachol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==Sorafenib & Atezolizumab== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sorafenib (Nexavar)]] | ||
+ | |||
+ | ==Tamoxifen & Everolimus== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | |||
+ | ==Tipifarnib monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Tipifarnib (Zarnestra)]] | ||
+ | |||
+ | ==Tivantinib monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Tivantinib (ARQ-197)]] | ||
+ | |||
+ | ==Atezolizumab & RT== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Capecitabine & Cisplatin (CX) & Simvastatin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Simvastatin (Zocor)]] | ||
+ | |||
+ | ==Capecitabine & Cisplatin (CX), Durvalumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Durvalumab (Imfinzi)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Capecitabine & Docetaxel (TX) & Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Capecitabine & Paclitaxel (XP)== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Capecitabine (Xeloda)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | |||
+ | ==Carboplatin & Docetaxel (DCb) & Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Carboplatin & Docetaxel (DCb) & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Carboplatin & Doxorubicin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | |||
+ | ==Carboplatin & Etoposide (CE) & Pravastatin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pravastatin (Pravachol)]] | ||
+ | |||
+ | ==Carboplatin & Etoposide (CE), then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | |||
+ | ==Carboplatin & Gemcitabine (GCb) & Celecoxib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Celecoxib (Celebrex)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Atezolizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Celecoxib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Celecoxib (Celebrex)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP), Atezolizumab, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Carboplatin, Docetaxel, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Carboplatin, Durvalumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Durvalumab (Imfinzi)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Carboplatin, Etoposide, Melphalan== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | |||
+ | ==Carboplatin, Fluorouracil, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Carboplatin, Gemcitabine, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==Carboplatin, Irinotecan, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Carboplatin, Paclitaxel, Trastuzumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trastuzumab (Herceptin)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Carmustine, Cisplatin, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carmustine (BCNU)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==CAVE & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cisplatin & Fluorouracil (CF), Durvalumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Durvalumab (Imfinzi)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cisplatin, Durvalumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Durvalumab (Imfinzi)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cisplatin, Fluorouracil, Vinblastine, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cisplatin, Lapatinib, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lapatinib (Tykerb)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cisplatin, Tirapazamine, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Tirapazamine (Tirazone)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cisplatin, Vinorelbine, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | *[[Vinorelbine (Navelbine)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==CMF & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Methotrexate (MTX)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cyclophosphamide & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cyclophosphamide & Thiotepa== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Thiotepa (Tepadina)]] | ||
+ | *[[Thiotepa (Thioplex)]] | ||
+ | |||
+ | ==Cyclophosphamide & Thiotepa, then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Thiotepa (Tepadina)]] | ||
+ | *[[Thiotepa (Thioplex)]] | ||
+ | |||
+ | ==Cyclophosphamide & Vincristine (CV)== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | |||
+ | ==Cyclophosphamide, Dacarbazine, Doxorubicin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | |||
+ | ==Cyclophosphamide, Dactinomycin, Fluorouracil== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Dactinomycin (Cosmegen)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | |||
+ | ==Cyclophosphamide, Daunorubicin, Vincristine, Dexamethasone== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Daunorubicin (Cerubidine)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Dexamethasone (Decadron)]] | ||
+ | |||
+ | ==Cyclophosphamide, DES, Fluorouracil== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Diethylstilbestrol (DES)]] | ||
+ | |||
+ | ==Cyclophosphamide, Etoposide, TBI, then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Cyclophosphamide, Mitoxantrone, Thiotepa== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | *[[Thiotepa (Tepadina)]] | ||
+ | *[[Thiotepa (Thioplex)]] | ||
+ | |||
+ | ==Cyclophosphamide, Mitoxantrone, Thiotepa, then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | *[[Thiotepa (Tepadina)]] | ||
+ | *[[Thiotepa (Thioplex)]] | ||
+ | |||
+ | ==Cytarabine & Ifosfamide== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Ifosfamide (Ifex)]] | ||
+ | |||
+ | ==Cytarabine & Imatinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Imatinib (Gleevec)]] | ||
+ | |||
+ | ==Dacarbazine & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Dacarbazine (DTIC)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Durvalumab & RT== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Durvalumab (Imfinzi)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Epirubicin & Fluorouracil== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | |||
+ | ==Epirubicin & Gemcitabine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | |||
+ | ==Epirubicin & Mitomycin (EM)== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Mitomycin (Mutamycin)]] | ||
+ | |||
+ | ==Epirubicin & Tamoxifen== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | |||
+ | ==Epirubicin & Vindesine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Epirubicin (Ellence)]] | ||
+ | *[[Vindesine (Eldisine)]] | ||
+ | |||
+ | ==Fluorouracil, Levamisole, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Levamisole (Ergamisol)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Fluorouracil, Semustine, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==FNC & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==IFL & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Interferon alfa-2a & Temsirolimus== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2a (Roferon-A)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Temsirolimus (Torisel)]] | ||
+ | |||
+ | ==Interferon alfa-2a & Vinblastine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon alfa-2a (Roferon-A)]] | ||
+ | |||
+ | ==Interferon gamma-1b monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Interferon gamma-1b (Actimmune)]] | ||
+ | |||
+ | ==Lenalidomide & Rituximab (R2) & Tafasitamab== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lenalidomide (Revlimid)]] | ||
+ | *[[Rituximab (Rituxan)]] | ||
+ | *[[Tafasitamab (Monjuvi)]] | ||
+ | |||
+ | ==Lenvatinib & Atezolizumab== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lenvatinib (Lenvima)]] | ||
+ | |||
+ | ==Levamisole & RT== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Levamisole (Ergamisol)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==LoDAC & Volasertib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Volasertib (BI-6727)]] | ||
+ | |||
+ | ==LoDAC & Vosaroxin== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | *[[Vosaroxin (SNS-595)]] | ||
+ | |||
+ | ==Lomustine & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Lomustine (CCNU)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Lomustine, Melphalan, TBI== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Lomustine (CCNU)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Lomustine, Melphalan, TBI, then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Lomustine (CCNU)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Mechlorethamine & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mechlorethamine (Mustargen)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Melphalan & Busulfan== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Busulfan (Myleran)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | |||
+ | ==Melphalan & Busulfan, then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Busulfan (Myleran)]] | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | |||
+ | ==Melphalan & TBI, then auto HSCT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Melphalan (Alkeran)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==mFOLFOX6, Atezolizumab, Bevacizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | |||
+ | ==mFOLFOX6, Bevacizumab, Cetuximab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Cetuximab (Erbitux)]] | ||
+ | |||
+ | ==mFOLFOX6, Bevacizumab, Panitumumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | *[[Panitumumab (Vectibix)]] | ||
+ | |||
+ | ==mFOLFOX6, Lenvatinib, Pembrolizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Pembrolizumab (Keytruda)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lenvatinib (Lenvima)]] | ||
+ | |||
+ | ==mFOLFOXIRI & Panitumumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | *[[Irinotecan (Camptosar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Panitumumab (Vectibix)]] | ||
+ | |||
+ | ==mini-CHVP== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Doxorubicin (Adriamycin)]] | ||
+ | *[[Teniposide (Vumon)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisone (Sterapred)]] | ||
+ | |||
+ | ==Mitomycin & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitomycin (Mutamycin)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Mitomycin & Vinblastine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitomycin (Mutamycin)]] | ||
+ | *[[Vinblastine (Velban)]] | ||
+ | |||
+ | ==Mitoxantrone, Vincristine, Prednisolone== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Mitoxantrone (Novantrone)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | ====Glucocorticoid therapy==== | ||
+ | *[[Prednisolone (Millipred)]] | ||
+ | |||
+ | ==Nimustine, Procarbazine, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Nimustine (ACNU)]] | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Nintedanib monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Nintedanib (Vargatef)]] | ||
+ | |||
+ | ==Niraparib & Dostarlimab== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Dostarlimab (Jemperli)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Niraparib (Zejula)]] | ||
+ | |||
+ | ==Niraparib & Pembrolizumab== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Pembrolizumab (Keytruda)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Niraparib (Zejula)]] | ||
+ | |||
+ | ==Nolatrexed monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Nolatrexed (Thymitaq)]] | ||
+ | |||
+ | ==Paclitaxel & Atezolizumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Atezolizumab (Tecentriq)]] | ||
+ | |||
+ | ==Paclitaxel & Pertuzumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Pertuzumab (Perjeta)]] | ||
+ | |||
+ | ==Paclitaxel & Sunitinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Sunitinib (Sutent)]] | ||
+ | |||
+ | ==Panitumumab & RT== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Panitumumab (Vectibix)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Pembrolizumab & RT== | ||
+ | ===Regimen=== | ||
+ | ====Immunotherapy==== | ||
+ | *[[Pembrolizumab (Keytruda)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Procarbazine & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Procarbazine (Matulane)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Semustine & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Semustine (MeCCNU)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Tamoxifen & RT== | ||
+ | ===Regimen=== | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Tamoxifen (Nolvadex)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Temozolomide, Bevacizumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Temozolomide (Temodar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Bevacizumab (Avastin)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Temozolomide, Nivolumab, RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Temozolomide (Temodar)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Nivolumab (Opdivo)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Teniposide & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Teniposide (Vumon)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==VAC & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Dactinomycin (Cosmegen)]] | ||
+ | *[[Vincristine (Oncovin)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | =Regimens that contain experimental (unapproved) drugs= | ||
+ | ==Adavosertib & Gemcitabine== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Adavosertib (MK-1775)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | |||
+ | ==Alisertib monotherapy== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Alisertib (MLN-8237)]] | ||
+ | |||
+ | ==Amonafide & Cytarabine== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Amonafide (Quinamed)]] | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | |||
+ | ==Barasertib & LoDAC== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cytarabine (Ara-C)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Barasertib (AZD-1152)]] | ||
+ | |||
+ | ==Buparlisib & Fulvestrant== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Buparlisib (BKM-120)]] | ||
+ | ====Endocrine therapy==== | ||
+ | *[[Fulvestrant (Faslodex)]] | ||
+ | |||
+ | ==Buparlisib & Paclitaxel== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Buparlisib (BKM-120)]] | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Agatolimod== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Agatolimod (PF-3512676)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Cediranib== | ||
+ | |||
+ | CP & Cediranib: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Cediranib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Cediranib (Recentin)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Farletuzumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Farletuzumab (MORAb-003)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Figitumumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Figitumumab (CP-751,871)]] | ||
+ | ==Carboplatin & Paclitaxel (CP) & Motesanib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Motesanib (AMG-706)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Rebimastat== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Rebimastat (BMS-275291)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Tirapazamine== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | *[[Tirapazamine (Tirazone)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Trebananib== | ||
+ | |||
+ | TC & Trebananib: '''<u>T</u>'''axol (Paclitaxel), '''<u>C</u>'''arboplatin, Trebananib | ||
+ | ===Regimen=== | ||
+ | {| class="wikitable sortable" style="width: 100%; text-align:center;" | ||
+ | !style="width: 20%"|Study | ||
+ | !style="width: 20%"|Dates of enrollment | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Evidence|Evidence]] | ||
+ | !style="width: 20%"|Comparator | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Comparative_efficacy|Comparative Efficacy]] | ||
+ | |- | ||
+ | |[https://doi.org/10.1016/S1470-2045(19)30178-0 Vergote et al. 2019 (TRINOVA-3)] | ||
+ | |2012-2014 | ||
+ | |style="background-color:#1a9851"|Phase 3 (E-esc) | ||
+ | |[[Ovarian_cancer#Carboplatin_.26_Paclitaxel_.28CP.29_3|TC]] | ||
+ | |style="background-color:#ffffbf"|Did not meet primary endpoint of PFS <br>(HR 0.93, 95% CI 0.79-1.09) | ||
+ | |- | ||
+ | |} | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trebananib (AMG-386)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Vadimezan== | ||
+ | CP & Vadimezan: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Vadimezan | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Vadimezan (AS-A404)]] | ||
+ | |||
+ | ==Carboplatin & Paclitaxel (CP) & Veliparib== | ||
+ | CP & Veliparib: '''<u>C</u>'''arboplatin, '''<u>P</u>'''aclitaxel, Veliparib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Carboplatin (Paraplatin)]] | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Veliparib (ABT-888)]] | ||
+ | |||
+ | ==Cediranib monotherapy== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Cediranib (Recentin)]] | ||
+ | |||
+ | ==Cisplatin & Gemcitabine (GC) & Veliparib== | ||
+ | |||
+ | GC & Veliparib: '''<u>G</u>'''emcitabine, '''<u>C</u>'''isplatin, Veliparib | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | *[[Cisplatin (Platinol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Veliparib (ABT-888)]] | ||
+ | |||
+ | ==Dinaciclib monotherapy== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Dinaciclib (SCH-727965)]] | ||
+ | |||
+ | ==Docetaxel & Bavituximab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Immunotherapy==== | ||
+ | *[[Bavituximab (PGN-401)]] | ||
+ | |||
+ | ==Docetaxel & Ganetespib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Docetaxel (Taxotere)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Ganetespib (STA-9090)]] | ||
+ | |||
+ | ==Erlotinib & Figitumumab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Figitumumab (CP-751,871)]] | ||
+ | |||
+ | ==Erlotinib & Onartuzumab== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Onartuzumab (MetMAb)]] | ||
+ | |||
+ | ==Erlotinib & Tivantinib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Erlotinib (Tarceva)]] | ||
+ | *[[Tivantinib (ARQ-197)]] | ||
+ | |||
+ | ==Everolimus & Vorolanib== | ||
+ | ===Regimen=== | ||
+ | ====Targeted therapy==== | ||
+ | *[[Everolimus (Afinitor)]] | ||
+ | *[[Vorolanib (CM-082)]] | ||
+ | |||
+ | ==FOLFOX4 & Cediranib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Fluorouracil (5-FU)]] | ||
+ | *[[Oxaliplatin (Eloxatin)]] | ||
+ | *[[Leucovorin (Folinic acid)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Cediranib (Recentin)]] | ||
+ | |||
+ | ==Gemcitabine & Ganitumab== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Ganitumab (AMG-479)]] | ||
+ | ==Gemcitabine & Masitinib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Gemcitabine (Gemzar)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Masitinib (AB-1010)]] | ||
+ | |||
+ | ==Ipatasertib & Paclitaxel== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Ipatasertib (GDC-0068)]] | ||
+ | |||
+ | ==Pegylated liposomal doxorubicin & Trebananib== | ||
+ | |||
+ | ===Regimen=== | ||
+ | {| class="wikitable sortable" style="width: 100%; text-align:center;" | ||
+ | !style="width: 20%"|Study | ||
+ | !style="width: 20%"|Dates of enrollment | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Evidence|Evidence]] | ||
+ | !style="width: 20%"|Comparator | ||
+ | !style="width: 20%"|[[Levels_of_Evidence#Comparative_efficacy|Comparative Efficacy]] | ||
+ | |- | ||
+ | |[https://doi.org/10.1016/j.ejca.2016.09.004 Marth et al. 2016 (TRINOVA-2)] | ||
+ | |2011-2013 | ||
+ | |style="background-color:#1a9851"|Phase 3 (E-esc) | ||
+ | |[[Ovarian_cancer#Pegylated_liposomal_doxorubicin_monotherapy|PLD]] | ||
+ | |style="background-color:#ffffbf"|Did not meet primary endpoint of PFS <br>(HR 0.92, 95% CI 0.68-1.24) | ||
+ | |- | ||
+ | |} | ||
+ | ====Chemotherapy==== | ||
+ | *[[Pegylated liposomal doxorubicin (Doxil)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trebananib (AMG-386)]] | ||
+ | |||
+ | ==Cyclophosphamide, Etoposide, Lestaurtinib, Methotrexate== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Cyclophosphamide (Cytoxan)]] | ||
+ | *[[Etoposide (Vepesid)]] | ||
+ | *[[Methotrexate (MTX)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Lestaurtinib (CEP-701)]] | ||
+ | |||
+ | ==Lobaplatin & RT== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Lobaplatin (D-19466)]] | ||
+ | ====Radiotherapy==== | ||
+ | *[[External beam radiotherapy]] | ||
+ | |||
+ | ==Paclitaxel & Trebananib== | ||
+ | ===Regimen=== | ||
+ | ====Chemotherapy==== | ||
+ | *[[Paclitaxel (Taxol)]] | ||
+ | ====Targeted therapy==== | ||
+ | *[[Trebananib (AMG-386)]] |
Latest revision as of 12:20, 23 June 2024
Regimens that have not proven to be superior to a standard-of-care comparison and are thus unlikely to be expanded upon unless new evidence comes forward. This page is primarily to drive the HemOnc Ontology and for historic interest.
Regimens composed solely of approved drugs
CapeOx & Cediranib
Regimen
Chemotherapy
Targeted therapy
CapeOx & Cetuximab
Regimen
Chemotherapy
Targeted therapy
CapeOx & Lapatinib
Regimen
Chemotherapy
Targeted therapy
CapeOx & RT
Regimen
Chemotherapy
Radiotherapy
CapeOx & Tislelizumab
Regimen
Chemotherapy
Immunotherapy
CapeOx, Bevacizumab, Cetuximab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Docetaxel (DCb) & Celecoxib
Regimen
Chemotherapy
Carboplatin & Docetaxel (DCb) & Cetuximab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Docetaxel (DCb) & Farletuzumab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Etoposide (CE) & Adebrelimab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Gemcitabine (GCb), Atezolizumab, Bevacizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
Carboplatin & Gemcitabine (GCb)/Erlotinib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Avelumab
Regimen
Chemotherapy
Immunotherapy
Carboplatin & Paclitaxel (CP) & Gefitinib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Interferon gamma-1b
Regimen
Chemotherapy
Immunotherapy
Carboplatin & Paclitaxel (CP), Bevacizumab, Cetuximab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP), Cetuximab, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
Carboplatin, Lenvatinib, Pemetrexed, Pembrolizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
Carboplatin, Vindesine, RT
Regimen
Chemotherapy
Radiotherapy
Carfilzomib & Ibrutinib
Regimen
Targeted therapy
Chlorambucil, Cisplatin, Doxorubicin
Regimen
Chemotherapy
Cisplatin & Docetaxel (DC) & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Cisplatin & Docetaxel (DC) & Cetuximab
Regimen
Chemotherapy
Targeted therapy
Cisplatin & Etoposide (EP) & Paclitaxel
Regimen
Chemotherapy
Cisplatin & Etoposide (EP) & Pravastatin
Regimen
Chemotherapy
Cisplatin & Etoposide (EP) & RT
Regimen
Chemotherapy
Radiotherapy
Cisplatin & Etoposide (EP)/Topotecan monotherapy
Regimen
Chemotherapy
Cisplatin & Fluorouracil (CF) & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Cisplatin & Fluorouracil (CF), Interferon alfa-2b, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Cisplatin & Fluorouracil (CF), Lenvatinib, Pembrolizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
Cisplatin & Fluorouracil (CF), Pembrolizumab, Trastuzumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
Cisplatin & Irinotecan (IC) & Cetuximab
Regimen
Chemotherapy
Targeted therapy
Cisplatin, Nintedanib, Pemetrexed
Regimen
Chemotherapy
Targeted therapy
Cisplatin, Paclitaxel, Cetuximab, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
Cisplatin, Paclitaxel, Erlotinib, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
Cisplatin, Paclitaxel, Lenvatinib, Pembrolizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
Cisplatin, Paclitaxel, Tislelizumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
3M
3M: Mitomycin, Mitoxantrone, Methotrexate
Regimen
Chemotherapy
4d+7
Regimen
Chemotherapy
4i+7
Regimen
Chemotherapy
5-FU & RT
Regimen
Chemotherapy
Radiotherapy
- Concurrent radiation therapy
5-FU, Cyclophosphamide, Dactinomycin
Regimen
Chemotherapy
7+2d
Regimen
Chemotherapy
7+3a
Regimen
Chemotherapy
7+3d & Azacitidine
Regimen
Chemotherapy
7+3d & GM-CSF
Regimen
Chemotherapy
Growth factor therapy
7+3d & Zosuquidar
Regimen
Chemotherapy
7+3i & Clofarabine
7+3i & Clofarabine: 7 days of cytarabine, 3 days of idarubicin, Clofarabine
Regimen
Chemotherapy
7+3i & Lenalidomide
7+3i & Lenalidomide: 7 days of cytarabine, 3 days of idarubicin, Lenalidomide
Regimen
Chemotherapy
Targeted therapy
7+4d
Regimen
Chemotherapy
7+4i
7+4i: 7 days of cytarabine, 4 days of idarubicin
Regimen
Chemotherapy
7+5d
7+5d: 7 days of cytarabine, 5 days of daunorubicin
Regimen
Chemotherapy
7+5i & Quinine
Regimen
Chemotherapy
10+3d
Regimen
Chemotherapy
A-C
Regimen
Chemotherapy
A-CHOP-14
Regimen
Chemotherapy
Glucocorticoid therapy
Targeted therapy
A-D
Regimen
Chemotherapy
A-D-CMF
Regimen
Chemotherapy
- Docetaxel (Taxotere)
- Doxorubicin (Adriamycin)
- Cyclophosphamide (Cytoxan)
- Methotrexate (MTX)
- Fluorouracil (5-FU)
Abiraterone & Enzalutamide
Regimen
Endocrine therapy
Abiraterone & Ipatasertib
Regimen
Endocrine therapy
Targeted therapy
Abiraterone, Radium-223, Prednisone
Regimen
Endocrine therapy
Radiotherapy
ABV
ABV: Adriamycin (Doxorubicin), Bleomycin, Vinblastine
Regimen
Chemotherapy
ABVP
ABVP: Adriamycin (Doxorubicin), Bleomycin, Vinblastine, Platinol (Cisplatin)
Regimen
Chemotherapy
AC-KP
Regimen
Chemotherapy
Targeted therapy
Antibody-drug conjugate therapy
ddAC-KP
Regimen
Chemotherapy
Targeted therapy
Antibody-drug conjugate therapy
Acalabrutinib & Venetoclax
Regimen
Targeted therapy
ACP
ACP: Atezolizumab, Carboplatin, Paclitaxel
Regimen
Immunotherapy
Chemotherapy
AD-CMF
Regimen
Chemotherapy
- Doxorubicin (Adriamycin)
- Docetaxel (Taxotere)
- Cyclophosphamide (Cytoxan)
- Methotrexate (MTX)
- Fluorouracil (5-FU)
Afatinib & Vinorelbine
Regimen
Chemotherapy
Targeted therapy
A-ICE
A-ICE: ATRA, Idarubicin, Cytarabine, Etoposide
Regimen
Targeted therapy
Chemotherapy
Altretamine & Melphalan
Regimen
Chemotherapy
AME
AME: Ara-C (Cytarabine), Mitoxantrone, Etoposide
Regimen
Chemotherapy
API
API: Adriamycin (Doxorubicin), Platinol (Cisplatin), Ifosfamide
Regimen
Chemotherapy
Amrubicin & Cisplatin
Regimen
Chemotherapy
Amsacrine monotherapy
Regimen
Chemotherapy
Amsacrine & Cytarabine
Regimen
Chemotherapy
Amsacrine & IDAC
Amsacrine & IDAC: Amsacrine & Intermediate Dose Ara-C (Cytarabine)
Regimen
Chemotherapy
Anastrozole and Everolimus
Regimen
Endocrine therapy
Targeted therapy
Anastrozole and Lapatinib
Regimen
Endocrine therapy
Targeted therapy
Anastrozole and Tamoxifen
Regimen
Endocrine therapy
Anlotinib monotherapy
Regimen
Targeted therapy
ATRA, Cytarabine, Etoposide
Regimen
Targeted therapy
Chemotherapy
AVML
AVML: Ara-C (Cytarabine), Vincristine, Methotrexate, Leucovorin
Regimen
Chemotherapy
Supportive therapy
Axitinb & Toripalimab
Regimen
Immunotherapy
Targeted therapy
Azacitidine & Eltrombopag
Regimen
Chemotherapy
Growth factor therapy
Azacitidine & Gilteritinib
Regimen
Chemotherapy
Targeted therapy
Binimetinib monotherapy
Regimen
Targeted therapy
Bortezomib & Bevacizumab
Regimen
Study | Dates of enrollment | Evidence | Comparator | Comparative Efficacy |
---|---|---|---|---|
White et al. 2012 (AMBER) | 2007-2009 | Randomized Phase 2 (E-esc) | Bortezomib | Did not meet primary endpoint of PFS (HR 0.74, 95% CI 0.43-1.28) |
Targeted therapy
Bortezomib & Siltuximab
Regimen
Study | Dates of enrollment | Evidence | Comparator | Comparative Efficacy |
---|---|---|---|---|
Orlowski et al. 2015 (CR012784) | 2006-2009 | Randomized Phase 2 (E-esc) | Bortezomib | Did not meet primary endpoint of PFS (HR 0.87, 95% CI 0.65-1.16) |
Targeted therapy
Immunosuppressive therapy
BTH (Docetaxel)
BTH: Bevacizumab, Taxotere (Docetaxel), Herceptin (Trastuzumab)
Regimen
Chemotherapy
Targeted therapy
BTOC
BTOC: BCNU, Thiotepa, Oncovin (Vincristine), Cyclophosphamide
Regimen
Chemotherapy
CAD
CAD: Cyclophosphamide, Adriamycin (Doxorubicin), DDP (Cisplatin)
Regimen
Chemotherapy
Capecitabine & Cisplatin (CX) & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Cisplatin (CX) & Ramucirumab
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Ruxolitinib
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Sorafenib
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Sunitinib
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Vinflunine
Regimen
Chemotherapy
Capecitabine & Vinorelbine (NX)
NX: Navelbine (Vinorelbine) & Xeloda (Capecitabine)
Regimen
Chemotherapy
Capecitabine, Cisplatin, Cetuximab, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
- Concurrent radiation therapy
Capecitabine, Erlotinib, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
- Concurrent radiation therapy
Capivasertib & Fulvestrant
Regimen
Endocrine therapy
Targeted therapy
CarboMIP
CarboMIP: Carboplatin, Mitomycin, Ifosfamide, Platinol (Cisplatin)
Regimen
Chemotherapy
Carboplatin & Epirubicin
Regimen
Chemotherapy
Carboplatin & Gemcitabine (GCb) & Gefitinib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Bexarotene
CP & Bexarotene: Carboplatin, Paclitaxel, Bexarotene
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Cetuximab
CP & Cetuximab: Carboplatin, Paclitaxel, Cetuximab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Erlotinib
CP & Erlotinib: Carboplatin, Paclitaxel, Erlotinib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Pegylated liposomal doxorubicin
CP & PLD: Carboplatin, Paclitaxel, Pegylated Liposomal Doxorubicin
TC & PLD: Taxol (Paclitaxel), Carboplatin, Pegylated Liposomal Doxorubicin
Regimen
Chemotherapy
Carboplatin & Paclitaxel (CP) & Sorafenib
CP & Sorafenib: Carboplatin, Paclitaxel, Sorafenib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Topotecan
TC & Topotecan: Taxol (Paclitaxel), Carboplatin, Topotecan
Regimen
Chemotherapy
Carboplatin & Topotecan
Regimen
Chemotherapy
CBM
CBM: Capecitabine, Bevacizumab, Mitomycin
Regimen
Chemotherapy
Targeted therapy
CCG
CCG: Cisplatin, Carboplatin, Gemcitabine
Regimen
Chemotherapy
Carboplatin & Etoposide (CE) & Ipilimumab
CE & Ipilimumab: Carboplatin, Etoposide, Ipilimumab
Regimen
Chemotherapy
Immunotherapy
Carboplatin & Etoposide (CE) & Thalidomide
CE & Thalidomide: Carboplatin, Etoposide, Thalidomide
Regimen
Chemotherapy
Targeted therapy
ChlVPP/EVA
ChlVPP/EVA: Chlorambucil, Vinblastine, Procarbazine, Prednisone alternating with Etoposide, Vincristine, Adriamycin (Doxorubicin)
Regimen
Chemotherapy, ChlVPP portion
Glucocorticoid therapy, ChlVPP portion
Chemotherapy, EVA portion
CIB
CIB: Cisplatin, Ifosfamide, Bleomycin
Regimen
Chemotherapy
Cisplatin & Gemcitabine (GC) & Erlotinib
GC & Erlotinib: Gemcitabine, Cisplatin, Erlotinib
Regimen
Chemotherapy
Targeted therapy
Cisplatin & Gemcitabine (GC) & Gefitinib
GC & Gefitinib: Gemcitabine, Cisplatin, Gefitinib
Regimen
Chemotherapy
Targeted therapy
Cisplatin & Gemcitabine (GC) & Nadroparin
GC & Nadroparin: Gemcitabine, Cisplatin, Nadroparin
Regimen
Chemotherapy
Anticoagulation
Cisplatin & Gemcitabine (GC) & Sorafenib
GC & Sorafenib: Gemcitabine, Cisplatin, Sorafenib
Regimen
Chemotherapy
Targeted therapy
Cisplatin & Gemcitabine (GC) & Tislelizumab
GC & Tislelizumab: Gemcitabine, Cisplatin, Tislelizumab
Regimen
Chemotherapy
Immunotherapy
Cisplatin & Methotrexate
Regimen
Chemotherapy
Cisplatin & Treosulfan
Regimen
Chemotherapy
Cisplatin & Vincristine
Regimen
Chemotherapy
Cisplatin, Avelumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
- Concurrent radiation therapy
Cisplatin, Pemetrexed, Gefitinib
Regimen
Study | Dates of enrollment | Evidence | Comparator | Comparative Efficacy |
---|---|---|---|---|
Soria et al. 2015 (IMPRESS) | 2012-2013 | Phase 3 (E-esc) | Cisplatin & Pemetrexed | Did not meet primary endpoint of PFS Median PFS: 5.4 vs 5.4 mo (HR 0.86, 95% CI 0.65-1.13) |
Chemotherapy
Targeted therapy
Cisplatin, Pemetrexed, RT
Regimen
Chemotherapy
Radiotherapy
- Concurrent radiation therapy
CODE
CODE: Cisplatin, Oncovin (Vincristine), Doxorubicin, Etoposide
Regimen
Chemotherapy
COPPEBVCAD
COPPEBVCAD: Cyclophosphamide, Oncovin (Vincristine), Procarbazine, Prednisone, Epirubicin, Bleomycin, Vinblastine, CCNU (Lomustine), Alkeran (Melphalan), DVA (Vindesine)
Regimen
Chemotherapy
- Cyclophosphamide (Cytoxan)
- Vincristine (Oncovin)
- Procarbazine (Matulane)
- Epirubicin (Ellence)
- Bleomycin (Blenoxane)
- Vinblastine (Velban)
- Lomustine (CCNU)
- Melphalan (Alkeran)
- Vindesine (Eldisine)
Glucocorticoid therapy
CYVADIC
CYVADIC: CYclophosphamide, Vincristine, ADriamycin (Doxorubicin), Imidazole Carboxamide (Dacarbazine)
Regimen
Chemotherapy
Dacarbazine & Dactinomycin
Regimen
Chemotherapy
Dacarbazine & Fotemustine
Regimen
Chemotherapy
Dacarbazine & Interferon alfa-2b
Regimen
Chemotherapy
Immunotherapy
Dacarbazine & Selumetinib
Regimen
Chemotherapy
Targeted therapy
Dacarbazine & Vindesine
Regimen
Chemotherapy
Dacarbazine, Fluorouracil, Semustine
Regimen
Chemotherapy
Dacarbazine, Fluorouracil, Semustine, Vincristine
Regimen
Chemotherapy
Dacarbazine, Fotemustine, Interferon alfa-2b
Regimen
Chemotherapy
Immunotherapy
Dacarbazine, Interferon alfa-2b, Tamoxifen
Regimen
Chemotherapy
Endocrine therapy
Immunotherapy
Dactinomycin, Doxorubicin, Vincristine
Regimen
Chemotherapy
DBCT
DBCT: Dacarbazine, BCNU (Carmustine), Cisplatin, Tamoxifen
Regimen
Chemotherapy
Endocrine therapy
Docetaxel & Erlotinib
Regimen
Chemotherapy
Targeted therapy
Docetaxel & Fluorouracil
Regimen
Chemotherapy
Docetaxel & Gefitinib
Regimen
Chemotherapy
Targeted therapy
Docetaxel & Lapatinib (TL)
Regimen
Chemotherapy
Targeted therapy
Docetaxel & Leuprolide
Regimen
Chemotherapy
Endocrine therapy
Docetaxel & Pertuzumab
Regimen
Chemotherapy
Targeted therapy
Docetaxel & Selumetinib
Regimen
Chemotherapy
Targeted therapy
Docetaxel & Sunitinib
Regimen
Chemotherapy
Targeted therapy
Docetaxel & Ziv-aflibercept
Regimen
Chemotherapy
Targeted therapy
Docetaxel, Lenalidomide, Prednisone
Regimen
Chemotherapy
Endocrine therapy
Targeted therapy
Docetaxel, Prednisone, Bevacizumab
Regimen
Chemotherapy
Endocrine therapy
Targeted therapy
Doxorubicin & Etoposide
Regimen
Chemotherapy
Doxorubicin & Paclitaxel
Regimen
Chemotherapy
Doxorubicin & Sorafenib
Regimen
Chemotherapy
Targeted therapy
Doxorubicin & Streptozocin
Regimen
Chemotherapy
Doxorubicin & Vinblastine (AV)
AV: Adriamycin (Doxorubicin) & Vinblastine
Regimen
Chemotherapy
Doxorubicin & Vinorelbine
Regimen
Chemotherapy
EAP
EAP: Etoposide, Adriamycin (Doxorubicin), Platinol (Cisplatin)
Regimen
Chemotherapy
ECVBP
ECVBP: Epirubicin, Cyclophosphamide, Vindesine, Bleomycin, Prednisone
Regimen
Chemotherapy
Glucocorticoid therapy
ECX & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
EC-KP
Regimen
Chemotherapy
Targeted therapy
Antibody-drug conjugate therapy
ddEC-KP
Regimen
Chemotherapy
Targeted therapy
Antibody-drug conjugate therapy
EC-TL (Docetaxel)
EC-TL: Epirubicin & Cyclophosphamide, followed by Taxotere (Docetaxel) & Lapatinib
EC-DL: Epirubicin & Cyclophosphamide, followed by Docetaxel & Lapatinib
Regimen
Chemotherapy, EC portion
Chemotherapy, TL portion
Targeted therapy, TL portion
ELF
ELF: Etoposide, Leucovorin, 5-FU (Fluorouracil)
Regimen
Chemotherapy
ELFE
ELFE: Etoposide, Leucovorin, 5-FU (Fluorouracil), Epirubicin
Regimen
Chemotherapy
Encorafenib monotherapy
Regimen
Targeted therapy
EP & Ipilimumab
EP & Ipilimumab: Etoposide, Platinol (Cisplatin), Ipilimumab
Regimen
Chemotherapy
Immunotherapy
EP, Tamoxifen, RT
EP, Tamoxifen, RT: Etoposide, Platinol (Cisplatin), Tamoxifen, Radiation Therapy
Regimen
Chemotherapy
Endocrine therapy
Radiotherapy
- Concurrent thoracic radiation therapy
Erlotinib & Sorafenib
Regimen
Targeted therapy
Erlotinib & Sunitinib
Regimen
Targeted therapy
Erlotinib, Bevacizumab, Panitumumab
Regimen
Targeted therapy
Erlotinib, Gemcitabine, Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Everolimus & Letrozole
Regimen
Endocrine therapy
Targeted therapy
Everolimus & Paclitaxel
Regimen
Chemotherapy
Targeted therapy
Everolimus & Sorafenib
Regimen
Targeted therapy
Everolimus & Vinorelbine
Regimen
Chemotherapy
Targeted therapy
Exemestane & Lapatinib
Regimen
Endocrine therapy
Targeted therapy
Exemestane & Palbociclib
Regimen
Endocrine therapy
Targeted therapy
E-GEMOX
E-GEMOX: Erlotinib, GEMcitabine, OXaliplatin
Regimen
Targeted therapy
Chemotherapy
FAP
FAP: Fluorouracil, Alfa interferon, Platinol (Cisplatin)
Regimen
Chemotherapy
Immunotherapy
FEC & HP
FEC & HP: Fluorouracil, Epirubicin, Cyclophosphamide, Herceptin (Trastuzumab), Pertuzumab
Regimen
Chemotherapy
Targeted therapy
ddFEC
ddFEC: dose-dense Fluorouracil, Epirubicin, Cyclophosphamide
Regimen
Chemotherapy
Supportive therapy
FLA
FLA: FLudarabine & Ara-C (Cytarabine)
Regimen
Chemotherapy
FLAG-Ida & GO
FLAG-Ida & GO: FLudarabine, Ara-C (Cytarabine), G-CSF (Lenograstim), Idarubicin, Gemtuzumab Ozogamicin
Regimen
Chemotherapy
- Fludarabine (Fludara) 30 mg/m2 IV once per day on days 2 to 6
- Cytarabine (Ara-C) 2000 mg/m2 IV over 4 hours once per day on days 2 to 6, given 4 hours after fludarabine
- Idarubicin (Idamycin) 8 mg/m2 IV once per day on days 4 to 6
Growth factor therapy
Antibody-drug conjugate therapy
FLAI
FLAI: FLudarabine, Ara-C (Cytarabine), Idarubicin
FIA: Fludarabine, Idarubicin, Ara-C (Cytarabine)
Regimen
Chemotherapy
FOLF-CB
FOLF-CB: FOLinic acid (Leucovorin), Fluorouracil, Cetuximab, Bevacizumab
Regimen
Chemotherapy
Targeted therapy
FOLFIRI & Regorafenib
FOLFIRI & Regorafenib: FOLinic acid (Leucovorin), Fluorouracil, IRInotecan, Regorafenib
Regimen
Chemotherapy
Targeted therapy
FOLFIRI & Simvastatin
FOLFIRI & Simvastatin: FOLinic acid (Leucovorin), Fluorouracil, IRInotecan, Simvastatin
Regimen
Chemotherapy
Targeted therapy
FOLFIRI & Sunitinib
FOLFIRI & Sunitinib: FOLinic acid (Leucovorin), Fluorouracil, IRInotecan, Sunitinib
Regimen
Chemotherapy
Targeted therapy
FULV & Cisplatin
FULV & Cisplatin: 5-FU, LeucoVorin, Cisplatin
Regimen
Chemotherapy
FULV & Edrecolomab
FULV & Edrecolomab: 5-FU, LeucoVorin, Edrecolomab
Regimen
Chemotherapy
Targeted therapy
FULV & Interferon alfa-2a
FULV & Interferon alfa-2a: 5-FU, LeucoVorin, Interferon alfa-2a
Regimen
Chemotherapy
Immunotherapy
FULV & Interferon alfa-2b
FULV & Interferon alfa-2b: 5-FU, LeucoVorin, Interferon alfa-2b
Regimen
Chemotherapy
Immunotherapy
FULV & Interferon alfa-2c
FULV & Interferon alfa-2c: 5-FU, LeucoVorin, Interferon alfa-2c
Regimen
Chemotherapy
Immunotherapy
FULV & Trimetrexate
FULV & Trimetrexate: 5-FU, LeucoVorin, Trimetrexate
Regimen
Chemotherapy
GVP
GVP: Gemcitabine, Vinorelbine, Platinol (Cisplatin)
Regimen
Chemotherapy
ICE, ATRA, GO
ICE, ATRA, GO: Idarubicin, Cytarabine, Etoposide, All-Trans Retinoic Acid, Gemtuzumab Ozogamicin
Regimen
Chemotherapy
Targeted therapy
Antibody-drug conjugate therapy
Ixabepilone & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
ME
ME: Mitoxantrone & Etoposide
Regimen
Chemotherapy
MEV
MEV: Mitomycin, Etoposide, Vindesine
Regimen
Chemotherapy
MFL
MFL: Methyl-lomustine (MeCCNU), 5-FU, Leucovorin
Regimen
Chemotherapy
MFT
MFL: Methotrexate, 5-FU, Tamoxifen
Regimen
Chemotherapy
Endocrine therapy
Mitoxantrone & Hydrocortisone
Regimen
Chemotherapy
Endocrine therapy
MMF
MMF: Methyl-lomustine (MeCCNU), Mitomycin, 5-FU
Regimen
Chemotherapy
MOPPEBVCAD
MOPPEBVCAD: Mechlorethamine, Oncovin (Vincristine), Procarbazine, Prednisone, Epirubicin, Bleomycin, Vinblastine, CCNU (Lomustine), Adriamycin (Doxorubicin), DVA (Vindesine)
Regimen
Chemotherapy
- Mechlorethamine (Mustargen)
- Vincristine (Oncovin)
- Procarbazine (Matulane)
- Epirubicin (Ellence)
- Bleomycin (Blenoxane)
- Vinblastine (Velban)
- Lomustine (CCNU)
- Doxorubicin (Adriamycin)
- Vindesine (Eldisine)
Glucocorticoid therapy
MPP
MPP: Melphalan, Prednisone, Procarbazine
Regimen
Chemotherapy
Glucocorticoid therapy
MTP
MTP: Myocet (Non-pegylated liposomal doxorubicin), Trastuzumab, Paclitaxel
Regimen
Chemotherapy
Targeted therapy
MVC
MVC: Mitomycin, Vindesine, Carboplatin
Regimen
Chemotherapy
NIP
NIP: Navelbine (Vinorelbine), Ifosfamide, Platinol (Cisplatin)
Regimen
Chemotherapy
Neratinib & Paclitaxel
Regimen
Targeted therapy
Chemotherapy
PD & Pembrolizumab
PD & Pembrolizumab: Pomalidomide, Dexamethasone, Pembrolizumab
Regimen
Study | Dates of enrollment | Evidence | Comparator | Comparative Efficacy |
---|---|---|---|---|
Mateos et al. 2019 (KEYNOTE-183) | 2016-2017 | Phase 3 (E-esc) | PD | Seems to have inferior PFS (HR 1.53, 95% CI 1.05-2.22) |
Targeted therapy
Glucocorticoid therapy
Immunotherapy
PEI
PEI: Platinol (Cisplatin), Etoposide, Ifosfamide
Regimen
Chemotherapy
PELF
PELF: Platinol (Cisplatin), Epirubicin, Leucovorin, 5-FU
Regimen
Chemotherapy
PGT
PGT: Platinol (Cisplatin), Gemcitabine, Taxol (Paclitaxel)
Regimen
Chemotherapy
PGV
PGV: Platinol (Cisplatin), Gemcitabine, Vinorelbine
CGV: Cisplatin, Gemcitabine, Vinorelbine
Regimen
Chemotherapy
Pemetrexed & Cetuximab
Regimen
Chemotherapy
Targeted therapy
Pemetrexed & Vandetanib
Regimen
Chemotherapy
Targeted therapy
Pixantrone & Rituximab
Regimen
Chemotherapy
Targeted therapy
PVI
PVI: Platinol (Cisplatin), Vindesine, Ifosfamide
VIP: Vindesine, Ifosfamide, Platinol (Cisplatin)
Regimen
Chemotherapy
R-BEACOPP
R-BEACOPP: Rituximab, Bleomycin, Etoposide, Adriamycin (Doxorubicin), Cyclophosphamide, Oncovin (Vincristine), Procarbazine, Prednisone
Regimen
Targeted therapy
Chemotherapy
- Bleomycin (Blenoxane)
- Etoposide (Vepesid)
- Doxorubicin (Adriamycin)
- Cyclophosphamide (Cytoxan)
- Vincristine (Oncovin)
- Procarbazine (Matulane)
Glucocorticoid therapy
R-MegaCHOEP
R-MegaCHOEP: Rituximab, high-dose (Mega) Cyclophosphamide, Hydroxydaunorubicin (Doxorubicin), Oncovin (Vincristine), Etoposide, Prednisone
Targeted therapy
Chemotherapy
Glucocorticoid therapy
Realgar-Indigo naturalis formulation monotherapy
Regimen
Targeted therapy
TCG
TCG: Taxol (Paclitaxel), Carboplatin, Gemcitabine
Regimen
Chemotherapy
TCHL (Docetaxel)
TCHL: Taxotere (Docetaxel), Carboplatin, Herceptin (Trastuzumab), Lapatinib
Regimen
Chemotherapy
Targeted therapy
TCL (Docetaxel)
TCL: Taxotere (Docetaxel), Carboplatin, Lapatinib
Regimen
Chemotherapy
Targeted therapy
TEC
TEC: Taxol (Paclitaxel), Epirubicin, Carboplatin
Regimen
Chemotherapy
Paclitaxel & Trastuzumab (TH) & Everolimus
TH & Everolimus: Taxol (Paclitaxel), Herceptin (Trastuzumab), Everolimus
Regimen
Chemotherapy
Targeted therapy
TPCV
TPCV: Thioguanine, Procarbazine, CCNU, Vincristine
Regimen
Chemotherapy
VADx
VADx: Vincristine, Ara-C (Cytarabine), Dexamethasone
Regimen
Chemotherapy
Glucocorticoid therapy
VAPEC-B
VAPEC-B: Vincristine, Adriamycin (Doxorubicin), Prednisolone, Etoposide, Cyclophosphamide, Bleomycin
Regimen
Chemotherapy
- Vincristine (Oncovin)
- Doxorubicin (Adriamycin)
- Etoposide (Vepesid)
- Cyclophosphamide (Cytoxan)
- Bleomycin (Blenoxane)
Glucocorticoid therapy
VBM (Vinblastine)
VBM: Vinblastine, Bleomycin, Methotrexate
Regimen
Chemotherapy
VCE
VCE: Vincristine, Carboplatin, Etoposide
Regimen
Chemotherapy
Vinorelbine & Hydrocortisone
Regimen
Chemotherapy
Endocrine therapy
VNC
VNC: Vincristine, Novantrone (Mitoxantrone), Cyclophosphamide
Regimen
Chemotherapy
VPV
VPV: Vinblastine, Platinol (Cisplatin), VP-16 (Etoposide)
Regimen
Chemotherapy
VTDC
VTDC: Velcade (Bortezomib), Thalidomide, Dexamethasone, Cyclophosphamide
Regimen
Targeted therapy
Glucocorticoid therapy
Chemotherapy
FEC-KP
Regimen
Chemotherapy
Targeted therapy
Antibody-drug conjugate therapy
Fluorouracil & Gemcitabine
Regimen
Chemotherapy
Fluorouracil & Interferon alfa-2a
Regimen
Chemotherapy
Immunotherapy
Fluorouracil & Interferon alfa-2b
Regimen
Chemotherapy
Immunotherapy
Fluorouracil & Melphalan
Regimen
Chemotherapy
Fluorouracil & Vinorelbine
Regimen
Chemotherapy
Fluorouracil, Interferon alfa-2a, Interleukin-2
Regimen
Chemotherapy
Immunotherapy
Fluorouracil, Olaparib, Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Fluorouracil, Semustine, Vincristine
Regimen
Chemotherapy
FOLFIRI, Bevacizumab, Cetuximab
Regimen
Chemotherapy
Targeted therapy
FULV & Interleukin-2
Regimen
Chemotherapy
Immunotherapy
Fulvestrant & Bevacizumab
Regimen
Endocrine therapy
Targeted therapy
Fulvestrant & Lapatinib
Regimen
Endocrine therapy
Targeted therapy
Gefitinib & Simvastatin
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Axitinib
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Cetuximab
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Cisplatin (GC) & LD IL-2
Regimen
Chemotherapy
Immunotherapy
Gemcitabine & Irinotecan (IG)
Regimen
Chemotherapy
Gemcitabine & Pemetrexed
Regimen
Chemotherapy
Gemcitabine & Pertuzumab
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Sorafenib
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Topotecan
Regimen
Chemotherapy
Gemcitabine & Treosulfan
Regimen
Chemotherapy
Gemcitabine & Vandetanib
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Vinorelbine (GN)
Regimen
Chemotherapy
Gemcitabine & Vismodegib
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Ziv-aflibercept
Regimen
Chemotherapy
Targeted therapy
Glasdegib monotherapy
Regimen
Targeted therapy
HiDAC & Etoposide
Regimen
Chemotherapy
HiDAC & Mitoxantrone
Regimen
Chemotherapy
HiDAC & Quizartinib
Regimen
Chemotherapy
Targeted therapy
HiDAC & Sorafenib
Regimen
Chemotherapy
Targeted therapy
HiDAC+3d
Regimen
Chemotherapy
HiDAC+3i
Regimen
Chemotherapy
Letrozole & Everolimus
Regimen
Endocrine therapy
Targeted therapy
Letrozole & Temsirolimus
Regimen
Endocrine therapy
Targeted therapy
Palbociclib & Tamoxifen
Regimen
Endocrine therapy
Targeted therapy
Pazopanib/Everolimus
Regimen
Targeted therapy
Pravastatin & Sorafenib
Regimen
Chemotherapy
Targeted therapy
Sorafenib & Atezolizumab
Regimen
Immunotherapy
Targeted therapy
Tamoxifen & Everolimus
Regimen
Endocrine therapy
Targeted therapy
Tipifarnib monotherapy
Regimen
Targeted therapy
Tivantinib monotherapy
Regimen
Targeted therapy
Atezolizumab & RT
Regimen
Immunotherapy
Radiotherapy
Capecitabine & Cisplatin (CX) & Simvastatin
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Cisplatin (CX), Durvalumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Capecitabine & Docetaxel (TX) & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Capecitabine & Paclitaxel (XP)
Regimen
Chemotherapy
Carboplatin & Docetaxel (DCb) & Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Docetaxel (DCb) & RT
Regimen
Chemotherapy
Radiotherapy
Carboplatin & Doxorubicin
Regimen
Chemotherapy
Carboplatin & Etoposide (CE) & Pravastatin
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Etoposide (CE), then auto HSCT
Regimen
Chemotherapy
Carboplatin & Gemcitabine (GCb) & Celecoxib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Atezolizumab
Regimen
Chemotherapy
Immunotherapy
Carboplatin & Paclitaxel (CP) & Celecoxib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP), Atezolizumab, Bevacizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
Carboplatin, Docetaxel, RT
Regimen
Chemotherapy
Radiotherapy
Carboplatin, Durvalumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Carboplatin, Etoposide, Melphalan
Regimen
Chemotherapy
Carboplatin, Fluorouracil, Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Carboplatin, Gemcitabine, Bevacizumab
Regimen
Chemotherapy
Targeted therapy
Carboplatin, Irinotecan, RT
Regimen
Chemotherapy
Radiotherapy
Carboplatin, Paclitaxel, Trastuzumab, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
Carmustine, Cisplatin, RT
Regimen
Chemotherapy
Radiotherapy
CAVE & RT
Regimen
Chemotherapy
Radiotherapy
Cisplatin & Fluorouracil (CF), Durvalumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Cisplatin, Durvalumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Cisplatin, Fluorouracil, Vinblastine, RT
Regimen
Chemotherapy
Radiotherapy
Cisplatin, Lapatinib, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
Cisplatin, Tirapazamine, RT
Regimen
Chemotherapy
Radiotherapy
Cisplatin, Vinorelbine, Bevacizumab
Regimen
Chemotherapy
Targeted therapy
CMF & RT
Regimen
Chemotherapy
Radiotherapy
Cyclophosphamide & RT
Regimen
Chemotherapy
Radiotherapy
Cyclophosphamide & Thiotepa
Regimen
Chemotherapy
Cyclophosphamide & Thiotepa, then auto HSCT
Regimen
Chemotherapy
Cyclophosphamide & Vincristine (CV)
Regimen
Chemotherapy
Cyclophosphamide, Dacarbazine, Doxorubicin
Regimen
Chemotherapy
Cyclophosphamide, Dactinomycin, Fluorouracil
Regimen
Chemotherapy
Cyclophosphamide, Daunorubicin, Vincristine, Dexamethasone
Regimen
Chemotherapy
Glucocorticoid therapy
Cyclophosphamide, DES, Fluorouracil
Regimen
Chemotherapy
Endocrine therapy
Cyclophosphamide, Etoposide, TBI, then auto HSCT
Regimen
Chemotherapy
Radiotherapy
Cyclophosphamide, Mitoxantrone, Thiotepa
Regimen
Chemotherapy
Cyclophosphamide, Mitoxantrone, Thiotepa, then auto HSCT
Regimen
Chemotherapy
Cytarabine & Ifosfamide
Regimen
Chemotherapy
Cytarabine & Imatinib
Regimen
Chemotherapy
Targeted therapy
Dacarbazine & RT
Regimen
Chemotherapy
Radiotherapy
Durvalumab & RT
Regimen
Immunotherapy
Radiotherapy
Epirubicin & Fluorouracil
Regimen
Chemotherapy
Epirubicin & Gemcitabine
Regimen
Chemotherapy
Epirubicin & Mitomycin (EM)
Regimen
Chemotherapy
Epirubicin & Tamoxifen
Regimen
Chemotherapy
Endocrine therapy
Epirubicin & Vindesine
Regimen
Chemotherapy
Fluorouracil, Levamisole, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Fluorouracil, Semustine, RT
Regimen
Chemotherapy
Radiotherapy
FNC & RT
Regimen
Chemotherapy
Radiotherapy
IFL & RT
Regimen
Chemotherapy
Radiotherapy
Interferon alfa-2a & Temsirolimus
Regimen
Immunotherapy
Targeted therapy
Interferon alfa-2a & Vinblastine
Regimen
Chemotherapy
Immunotherapy
Interferon gamma-1b monotherapy
Regimen
Immunotherapy
Lenalidomide & Rituximab (R2) & Tafasitamab
Regimen
Targeted therapy
Lenvatinib & Atezolizumab
Regimen
Immunotherapy
Targeted therapy
Levamisole & RT
Regimen
Immunotherapy
Radiotherapy
LoDAC & Volasertib
Regimen
Chemotherapy
Targeted therapy
LoDAC & Vosaroxin
Regimen
Chemotherapy
Lomustine & RT
Regimen
Chemotherapy
Radiotherapy
Lomustine, Melphalan, TBI
Regimen
Chemotherapy
Radiotherapy
Lomustine, Melphalan, TBI, then auto HSCT
Regimen
Chemotherapy
Radiotherapy
Mechlorethamine & RT
Regimen
Chemotherapy
Radiotherapy
Melphalan & Busulfan
Regimen
Chemotherapy
Melphalan & Busulfan, then auto HSCT
Regimen
Chemotherapy
Melphalan & TBI, then auto HSCT
Regimen
Chemotherapy
Radiotherapy
mFOLFOX6, Atezolizumab, Bevacizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
mFOLFOX6, Bevacizumab, Cetuximab
Regimen
Chemotherapy
Targeted therapy
mFOLFOX6, Bevacizumab, Panitumumab
Regimen
Chemotherapy
Targeted therapy
mFOLFOX6, Lenvatinib, Pembrolizumab
Regimen
Chemotherapy
Immunotherapy
Targeted therapy
mFOLFOXIRI & Panitumumab
Regimen
Chemotherapy
Targeted therapy
mini-CHVP
Regimen
Chemotherapy
Glucocorticoid therapy
Mitomycin & RT
Regimen
Chemotherapy
Radiotherapy
Mitomycin & Vinblastine
Regimen
Chemotherapy
Mitoxantrone, Vincristine, Prednisolone
Regimen
Chemotherapy
Glucocorticoid therapy
Nimustine, Procarbazine, RT
Regimen
Chemotherapy
Radiotherapy
Nintedanib monotherapy
Regimen
Targeted therapy
Niraparib & Dostarlimab
Regimen
Immunotherapy
Targeted therapy
Niraparib & Pembrolizumab
Regimen
Immunotherapy
Targeted therapy
Nolatrexed monotherapy
Regimen
Chemotherapy
Paclitaxel & Atezolizumab
Regimen
Chemotherapy
Immunotherapy
Paclitaxel & Pertuzumab
Regimen
Chemotherapy
Targeted therapy
Paclitaxel & Sunitinib
Regimen
Chemotherapy
Targeted therapy
Panitumumab & RT
Regimen
Targeted therapy
Radiotherapy
Pembrolizumab & RT
Regimen
Immunotherapy
Radiotherapy
Procarbazine & RT
Regimen
Chemotherapy
Radiotherapy
Semustine & RT
Regimen
Chemotherapy
Radiotherapy
Tamoxifen & RT
Regimen
Endocrine therapy
Radiotherapy
Temozolomide, Bevacizumab, RT
Regimen
Chemotherapy
Targeted therapy
Radiotherapy
Temozolomide, Nivolumab, RT
Regimen
Chemotherapy
Immunotherapy
Radiotherapy
Teniposide & RT
Regimen
Chemotherapy
Radiotherapy
VAC & RT
Regimen
Chemotherapy
Radiotherapy
Regimens that contain experimental (unapproved) drugs
Adavosertib & Gemcitabine
Regimen
Targeted therapy
Chemotherapy
Alisertib monotherapy
Regimen
Targeted therapy
Amonafide & Cytarabine
Regimen
Chemotherapy
Barasertib & LoDAC
Regimen
Chemotherapy
Targeted therapy
Buparlisib & Fulvestrant
Regimen
Targeted therapy
Endocrine therapy
Buparlisib & Paclitaxel
Regimen
Targeted therapy
Chemotherapy
Carboplatin & Paclitaxel (CP) & Agatolimod
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Cediranib
CP & Cediranib: Carboplatin, Paclitaxel, Cediranib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Farletuzumab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Figitumumab
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Motesanib
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Rebimastat
Regimen
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Tirapazamine
Regimen
Chemotherapy
Carboplatin & Paclitaxel (CP) & Trebananib
TC & Trebananib: Taxol (Paclitaxel), Carboplatin, Trebananib
Regimen
Study | Dates of enrollment | Evidence | Comparator | Comparative Efficacy |
---|---|---|---|---|
Vergote et al. 2019 (TRINOVA-3) | 2012-2014 | Phase 3 (E-esc) | TC | Did not meet primary endpoint of PFS (HR 0.93, 95% CI 0.79-1.09) |
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Vadimezan
CP & Vadimezan: Carboplatin, Paclitaxel, Vadimezan
Chemotherapy
Targeted therapy
Carboplatin & Paclitaxel (CP) & Veliparib
CP & Veliparib: Carboplatin, Paclitaxel, Veliparib
Regimen
Chemotherapy
Targeted therapy
Cediranib monotherapy
Regimen
Targeted therapy
Cisplatin & Gemcitabine (GC) & Veliparib
GC & Veliparib: Gemcitabine, Cisplatin, Veliparib
Regimen
Chemotherapy
Targeted therapy
Dinaciclib monotherapy
Regimen
Targeted therapy
Docetaxel & Bavituximab
Regimen
Chemotherapy
Immunotherapy
Docetaxel & Ganetespib
Regimen
Chemotherapy
Targeted therapy
Erlotinib & Figitumumab
Regimen
Targeted therapy
Erlotinib & Onartuzumab
Regimen
Targeted therapy
Erlotinib & Tivantinib
Regimen
Targeted therapy
Everolimus & Vorolanib
Regimen
Targeted therapy
FOLFOX4 & Cediranib
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Ganitumab
Regimen
Chemotherapy
Targeted therapy
Gemcitabine & Masitinib
Regimen
Chemotherapy
Targeted therapy
Ipatasertib & Paclitaxel
Regimen
Chemotherapy
Targeted therapy
Pegylated liposomal doxorubicin & Trebananib
Regimen
Study | Dates of enrollment | Evidence | Comparator | Comparative Efficacy |
---|---|---|---|---|
Marth et al. 2016 (TRINOVA-2) | 2011-2013 | Phase 3 (E-esc) | PLD | Did not meet primary endpoint of PFS (HR 0.92, 95% CI 0.68-1.24) |