How I Treat

The "How I Treat" series has been published by Blood for several decades and covers a wide variety of topics in malignant and classical hematology. While these articles are not considered to be formal guidelines, they are considered highly reputable sources of expert opinion. They cover topics ranging from commonly encountered hematologic conditions with a large evidence base, to very rare conditions with only case reports to guide treatment. The purpose of this page is to consolidate the links to all known published How I Treat articles.

In the first two sections (malignant hematology and classical hematology), articles are presented by condition, in reverse chronological order. In the third section, articles are gathered under "special considerations" such as pregnancy and hematologic disease. The fourth section contains miscellaneous topics that do not easily fit into the above categories. Given the rapid change in evidence in many areas of hematology, readers are encouraged to consider any article published 5+ years ago to be for historical purposes, only.

Malignant hematology

Acute leukemias

Mixed-phenotype acute leukemia (MPAL)

• 2015: Wolach & Stone. How I treat mixed-phenotype acute leukemia PubMed

Myeloid neoplasms

Acute lymphoblastic leukemia (ALL)

• 2023: Kopmar & Cassaday. How I prevent and treat central nervous system disease in adults with acute lymphoblastic leukemia PubMed
• 2023: Myers et al. How I use risk factors for success or failure of CD19 CAR T cells to guide management of children and AYA with B-cell ALL PubMed
• 2023: Si Lim et al. How I treat newly diagnosed and refractory T-cell acute lymphoblastic lymphoma in children and young adults PubMed
• 2020: Aldoss & Douer. How I treat the toxicities of pegasparaginase in adults with acute lymphoblastic leukemia PubMed
• 2020: Aldoss & Forman. How I treat adults with advanced acute lymphoblastic leukemia eligible for CD19-targeted immunotherapy PubMed
• 2020: Hunger & Raetz. How I treat relapsed acute lymphoblastic leukemia in the pediatric population PubMed
• 2020: Teachey & O'Connor How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children PubMed
• 2019: Ravandi. How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia PubMed
• 2015: Curran & Stock. How I treat acute lymphoblastic leukemia in older adolescents and young adults PubMed
• 2015: Frey & Luger. How I treat adults with relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia PubMed
• 2015: Litzow & Ferrando. How I treat T-cell acute lymphoblastic leukemia in adults PubMed
• 2013: Gökbuget. How I treat older patients with ALL PubMed
• 2012: Locatelli et al. How I treat relapsed childhood acute lymphoblastic leukemia PubMed
• 2007: Rowe & Goldstone. How I treat acute lymphocytic leukemia in adults PubMed

Acute myeloid leukemia (AML)

• 2024: Thol et al. How I treat refractory and relapsed acute myeloid leukemia PubMed
  • 2020: DeWolf & Tallman. How I treat relapsed or refractory AML PubMed
• 2023: Biederstädt & Rezvani. How I treat high-risk acute myeloid leukemia using preemptive adoptive cellular immunotherapy PubMed
• 2023: El Chaer et al. How I treat AML incorporating the updated classifications and guidelines PubMed
• 2021: Falini et al. How I diagnose and treat NPM1-mutated AML PubMed
• 2021: Rubnitz & Kaspers. How I treat pediatric acute myeloid leukemia PubMed
• 2020: DiNardo & Wei. How I treat acute myeloid leukemia in the era of new drugs PubMed
• 2016: Ofran et al. How I treat acute myeloid leukemia presenting with preexisting comorbidities PubMed
• 2016: Peffault de Latour & Soulier. How I treat MDS and AML in Fanconi anemia PubMed
• 2016: Pratz & Levis. How I treat FLT3-mutated AML PubMed
• 2015: Röllig & Ehninger. How I treat hyperleukocytosis in acute myeloid leukemia PubMed
• 2014: Ossenkoppele & Löwenberg. How I treat the older patient with acute myeloid leukemia PubMed
• 2011: Bakst et al. How I treat extramedullary acute myeloid leukemia PubMed

Acute promyelocytic leukemia (APL)

• 2014: Sanz & Motesinos. How we prevent and treat differentiation syndrome in patients with acute promyelocytic leukemia PubMed
• 2009: Tallman & Altman. How I treat acute promyelocytic leukemia PubMed

Chronic myeloid leukemia (CML)

• 2022: Berman. How I treat chronic-phase chronic myelogenous leukemia
• 2019: Hijiya & Suttorp. How I treat chronic myeloid leukemia in children and adolescents
• 2016: Gotlib. How I treat atypical chronic myeloid leukemia PubMed
• 2012: Cortes & Kantarjian. How I treat newly diagnosed chronic phase CML PubMed
• 2009: Radich. How I monitor residual disease in chronic myeloid leukemia PubMed

Chronic myelomonocytic leukemia (CMML)

• 2017: Solary & Itzykson. How I treat chronic myelomonocytic leukemia PubMed

Essential thrombocythemia (ET)

• 2018: Odenike. How I treat the blast phase of Philadelphia chromosome-negative myeloproliferative neoplasms PubMed
• 2016: Rumi & Cazzola. How I treat essential thrombocythemia PubMed

Hypereosinophilic syndrome (HES)

• 2015: Klion. How I treat hypereosinophilic syndromes PubMed

Myelodysplastic syndrome (MDS)

• 2024: Mina et al. How I reduce and treat posttransplant relapse of MDS PubMed
• 2019: Santini. How I treat MDS after hypomethylating agent failure
• 2018: Locatelli & Strahm. How I treat myelodysplastic syndromes of childhood PubMed
• 2018: Steensma. How I use molecular genetic tests to evaluate patients who have or may have myelodysplastic syndromes PubMed
• 2016: Peffault de Latour & Soulier. How I treat MDS and AML in Fanconi anemia PubMed
• 2013: Sekeres & Cutler. How we treat higher-risk myelodysplastic syndromes PubMed
• 2013: Fenaux & Adès. How we treat lower-risk myelodysplastic syndromes

Myelofibrosis (MF)

• 2023: Kröger et al. How I treat transplant-eligible patients with myelofibrosis PubMed
• 2018: Odenike. How I treat the blast phase of Philadelphia chromosome-negative myeloproliferative neoplasms PubMed
• 2018: Pardanani & Tefferi. How I treat myelofibrosis after failure of JAK inhibitors PubMed
• 2011: Tefferi. How I treat myelofibrosis PubMed

Polycythemia vera (PV)

• 2019: Spivak. How I treat polycythemia vera PubMed
• 2018: Odenike. How I treat the blast phase of Philadelphia chromosome-negative myeloproliferative neoplasms PubMed
• 2014: Vannucchi. How I treat polycythemia vera PubMed

Systemic mastocytosis

• 2013: Pardanani. How I treat patients with indolent and smoldering mastocytosis (rare conditions but difficult to manage) PubMed

Lymphoid neoplasms

Adult T-cell leukemia-lymphoma (ATLL)

• 2021: Cook & Phillips How I treat adult T-cell leukemia/lymphoma PubMed

Anaplastic large cell lymphoma

• 2018: Metha-Shah et al. How I treat breast implant-associated anaplastic large cell lymphoma PubMed

Burkitt lymphoma (BL)

• 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
• 2014: Jacobson & LaCasce. How I treat Burkitt lymphoma in adults PubMed

Castleman disease

• 2010: Bower. How I treat HIV-associated multicentric Castleman disease PubMed

Chronic lymphocytic leukemia (CLL/SLL)

• 2021: Lew et al. How I treat chronic lymphocytic leukemia after venetoclax
• 2019: Stephens & Byrd. How I manage ibrutinib intolerance and complications in patients with chronic lymphocytic leukemia
• 2018: Brown. How I treat CLL patients with ibrutinib PubMed
• 2018: Gribben. How and when I do allogeneic transplant in CLL PubMed
• 2017: Woyach. How I manage ibrutinib-refractory chronic lymphocytic leukemia PubMed
• 2009: Gribben. How I treat CLL up front PubMed

Classical Hodgkin lymphoma (cHL)

• 2021: Epperla & Herrera. How I incorporate novel agents into the treatment of classical Hodgkin lymphoma
• 2015: Alinari & Blum. How I treat relapsed classical Hodgkin lymphoma after autologous stem cell transplant PubMed
• 2014: Uldrick & Little. How I treat classical Hodgkin lymphoma in patients infected with human immunodeficiency virus PubMed

CNS lymphoma

• 2023: Alderuccio et al. How I treat secondary CNS involvement by aggressive lymphomas PubMed
• 2017: Chin & Cheah. How I treat patients with aggressive lymphoma at high risk of CNS relapse PubMed
• 2013: Rubenstein et al. How I treat CNS lymphomas PubMed

Cutaneous T-cell lymphoma (CTCL)

• 2019: Shinohara & Shustov. How I treat primary cutaneous CD30 + lymphoproliferative disorders
• 2016: Whittaker et al. How I treat mycosis fungoides and Sézary syndrome PubMed

Diffuse large B-cell lymphoma (DLBCL)

• 2023: Lugtenburg & Mutsaers. How I treat older patients with DLBCL in the frontline setting PubMed

Follicular lymphoma (FL)

• 2019: Casulo & Barr. How I treat early-relapsing follicular lymphoma PubMed

High-grade B-cell lymphoma (HGBL)

• 2017: Friedberg. How I treat double-hit lymphoma PubMed

HIV-associated lymphoma

• 2014: Uldrick & Little. How I treat classical Hodgkin lymphoma in patients infected with human immunodeficiency virus PubMed
• 2012: Dunleavy & Wilson. How I treat HIV-associated lymphoma PubMed
• 2010: Bower. How I treat HIV-associated multicentric Castleman disease PubMed

Large granular lymphocytic leukemia (T-LGL)

• 2011: Lamy & Loughran. How I treat LGL leukemia PubMed

Mantle cell lymphoma (MCL)

• 2009: Ghielmini & Zucca. How I treat mantle cell lymphoma PubMed

NK- and T-cell lymphoma (NKTCL)

• 2013: Tse & Kwong. How I treat NK/T-cell lymphomas PubMed

Nodular lymphocyte-predominant Hodgkin lymphoma (NLP-HL)

• 2020: Eichenauer & Engert. How I treat nodular lymphocyte-predominant Hodgkin Lymphoma
• 2013: Advani & Hoppe. How I treat nodular lymphocyte predominant Hodgkin lymphoma PubMed

Peripheral T-cell lymphoma (PTCL)

• 2014: Moskowitz et al. How I treat the peripheral T-cell lymphomas PubMed

Post-transplant lymphoproliferative disorder (PTLD)

• 2023: Amengual & Pro. How I treat posttransplant lymphoproliferative disorder PubMed
• 2015: Dierickx et al. How I treat posttransplant lymphoproliferative disorders PubMed

Primary mediastinal B-cell lymphoma (PMBCL)

• 2018: Giulino-Roth. How I treat primary mediastinal B-cell lymphoma PubMed

Prolymphocytic leukemia (T-PLL)

• 2012: Dearden. How I treat prolymphocytic leukemia PubMed

Splenic lymphoma

• 2011: Iannitto & Tripodo. How I diagnose and treat splenic lymphomas PubMed

Transformed lymphoma

• 2014: Parikh et al. How we treat Richter syndrome PubMed

Waldenström macroglobulinemia (WM)

• 2019: Dimopoulos & Kastritis. How I treat Waldenström macroglobulinemia PubMed
• 2015: Treon. How I treat Waldenström macroglobulinemia PubMed

Plasma cell dyscrasias

Light-chain (AL) amyloidosis

• 2022: Palladini & Merlini. How I treat AL amyloidosis
• 2012: Leung et al. How I treat amyloidosis: the importance of accurate diagnosis and amyloid typing PubMed

MGUS

• 2013: Fermand et al. How I treat monoclonal gammopathy of renal significance (MGRS) PubMed

Multiple myeloma (MM)

• 2023: van de Donk. How We Manage Newly Diagnosed Multiple Myeloma With Circulating Tumor Cells
• 2022: Kastritis et al. How I treat relapsed multiple myeloma
• 2022: Perrot. How I treat frontline transplantation-eligible multiple myeloma PubMed
• 2022: Vaxman & Gertz. How I approach smoldering multiple myeloma
• 2022: Zamagni et al. How I treat high-risk multiple myeloma
• 2017: Harousseau & Attal. How I treat first relapse of myeloma PubMed
• 2017: Moreau. How I treat myeloma with new agents PubMed
• 2015: Larocca & Palumbo. How I treat fragile myeloma patients PubMed
• 2015: Lonial et al. How I treat high-risk myeloma PubMed
• 2015: Touzeau & Moreau. How I treat extramedullary myeloma PubMed
• 2014: Bladé et al. How I treat relapsed myeloma PubMed
• 2014: Gertz & Dingli. How we manage autologous stem cell transplantation for patients with multiple myeloma PubMed
• 2010: Mehta et al. How I treat elderly patients with myeloma PubMed
• 2009: Stewart et al. How I treat multiple myeloma in younger patients PubMed

Plasma cell leukemia (PCL)

• 2012: van de Donk et al. How I treat plasma cell leukemia PubMed

Smoldering multiple myeloma (SMM)

• 2014: Ghobrial & Landgren. How I treat smoldering multiple myeloma PubMed

Histiocytic disorders

Hemophagocytic lymphohistiocytosis (HLH)

• 2015: Schram & Berliner. How I treat hemophagocytic lymphohistiocytosis in the adult patient PubMed

Langerhans cell histiocytosis (LCH)

• 2015: Allen et al. How I treat Langerhans cell histiocytosis PubMed

Classical hematology

Hemostasis and thrombosis

• 2023: Samuelson Bannow & Konkle. How I approach bleeding in hospitalized patients PubMed
• 2021: Baker & O'Donnell. How I treat bleeding disorder of unknown cause PubMed
• 2016: Martin & Key. How I treat patients with inherited bleeding disorders who need anticoagulant therapy PubMed
• 2015: Pavord & Maybury. How I treat postpartum hemorrhage PubMed
• 2014: Johansson et al. How I treat patients with massive hemorrhage PubMed
• 2014: Levy & Goodnough. How I use fibrinogen replacement therapy in acquired bleeding PubMed

Acquired thrombotic thrombocytopenic purpura (aTTP)

• 2022: Akwaa et al. How I treat immune-mediated thrombotic thrombocytopenic purpura after hospital discharge
• 2020: Ferrari & Peyvandi. How I treat thrombotic thrombocytopenic purpura in pregnancy
• 2015: Sayani & Abrams. How I treat refractory thrombotic thrombocytopenic purpura PubMed

Antiphospholipid antibody syndrome (APS)

• 2021: Cohen & Isenberg. How I treat anticoagulant-refractory thrombotic antiphospholipid syndrome PubMed
• 2015: Ortel et al. How I treat catastrophic thrombotic syndromes PubMed

Arterial thromboembolism (ATE)

• 2020: May & Moll. How I treat unexplained arterial thrombosis

Disseminated intravascular coagulation (DIC)

• 2018: Levi & Scully. How I treat disseminated intravascular coagulation PubMed

Hemophilia

• 2020: Leebeek et al. How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease
• 2019: Young. How I treat children with haemophilia and inhibitors
• 2015: Leissinger et al. How I use bypassing therapy for prophylaxis in patients with hemophilia A and inhibitors PubMed
• 2012: Mannucci & Mancuso. How we choose factor VIII to treat hemophilia PubMed

Heparin-induced thrombocytopenia (HIT)

• 2016: Warkentin & Anderson. How I treat patients with a history of heparin-induced thrombocytopenia PubMed

Thrombotic microangiopathy (TMA)

• 2023: Doreille et al. How I treat thrombotic microangiopathy in the era of rapid genomics
• 2021: Thomas & Scully. How I treat microangiopathic hemolytic anemia in patients with cancer

Venous thromboembolism (VTE)

• 2023: Akpan & Hunt. How I approach the prevention and treatment of thrombotic complications in hospitalized patients PubMed
• 2022: Schmidt & Lee. How I treat and prevent venous thrombotic complications in patients with lymphoma
• 2020: Klok & Huisman. How I assess and manage the risk of bleeding in patients treated for venous thromboembolism
• 2020: Middeldorp & Ganzevoort. How I treat venous thromboembolism in pregnancy
• 2020: Wang & Carrier. How I treat obese patients with oral anticoagulants
• 2019: Pabinger & Thaler. How I treat patients with hereditary antithrombin deficiency
• 2019: Chan & Eikelbloom. How I manage anticoagulant therapy in older individuals with atrial fibrillation or venous thromboembolism
• 2019: Kraaijpoel & Carrier. How I treat cancer-associated venous thromboembolism
• 2018: Rabinovich & Kahn. How I treat the postthrombotic syndrome PubMed
• 2018: Shet & Wun. How I diagnose and treat venous thromboembolism in sickle cell disease
• 2018: Vedantham & Sista. How I use catheter-directed interventional therapy to treat patients with venous thromboembolism PubMed
• 2017: Schulman. How I treat recurrent venous thromboembolism in patients receiving anticoagulant therapy PubMed
• 2017: Young. How I treat pediatric venous thromboembolism PubMed
• 2015: Kyrle. How I treat recurrent deep-vein thrombosis PubMed
• 2015: O'Connell. How I treat incidental pulmonary embolism PubMed
• 2014: Ageno et al. How I treat splanchnic vein thrombosis PubMed
• 2014: Palareti. How I treat isolated distal deep vein thrombosis (IDDVT) PubMed
• 2012: Dobromirski & Cohen. How I manage venous thromboembolism risk in hospitalized medical patients PubMed

von Willebrand disease (vWD)

• 2020: Biguzzi et al. How I treat gastrointestinal bleeding in congenital and acquired von Willebrand disease
• 2020: Leebeek et al. How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease
• 2019: Lavin & O'Donnell. How I treat low von Willebrand factor levels
• 2018: Kruse-Jarres & Johnsen. How I treat type 2B von Willebrand disease PubMed
• 2014: Tosetto & Castaman. How I treat type 2 variant forms of von Willebrand disease PubMed
• 2011: Tiede et al. How I treat the acquired von Willebrand syndrome PubMed

Cytopenias

Acquired pure red cell aplasia

• 2021: Gurnari & Maciejewski. How I manage acquired pure red cell aplasia in adults PubMed

Anemia

• 2023: Carson & Brittenham. How I treat anemia with red blood cell transfusion and iron PubMed
• 2021: Gurnari & Maciejewski. How I manage acquired pure red cell aplasia in adults
• 2020: Anand & Gupta. How I treat anemia in heart failure
• 2020: Fishbane & Coyne. How I treat renal anemia
• 2020: Gilreath & Rodgers. How I treat cancer-associated anemia
• 2020: Shander et al. How I treat anemia in the perisurgical setting
• 2016: Achebe & Gafter-Gvili. How I treat anemia in pregnancy: iron, cobalamin, and folate PubMed
• 2014: Hershko & Camaschella. How I treat unexplained refractory iron deficiency anemia

Aplastic anemia

• 2017: Bacigalupo. How I treat acquired aplastic anemia PubMed

Autoimmune cytopenia

• 2022: Porpaczy & Jäger. How I manage autoimmune cytopenias in patients with lymphoid cancer PubMed

Immune thrombocytopenia (ITP)

• 2021: Ghanima et al. How I treat primary ITP in adult patients who are unresponsive to or dependent on corticosteroid treatment
• 2016: Cuker & Neunert. How I treat refractory immune thrombocytopenia PubMed

Neutropenia & leukopenia

• 2014: Gibson & Berliner. How we evaluate and treat neutropenia in adults PubMed

Thrombocytopenia and platelet dysfunction

• 2023: Stanworth & Mumford. How I diagnose and treat neonatal thrombocytopenia PubMed
• 2022: Stanworth & Shah. How I use platelet transfusions PubMed
• 2022: Fiore et al. How I manage pregnancy in women with Glanzmann thrombasthenia
• 2021: Kyrle & Eichinger. How I manage cyclic thrombocytopenia
• 2016: Greinacher & Selleng. How I evaluate and treat thrombocytopenia in the intensive care unit patient PubMed
• 2012: Gernsheimer et al. How I treat thrombocytopenia in pregnancy PubMed

WHIM syndrome

• 2017: Badolato et al. How I treat warts, hypogammaglobulinemia, infections, and myelokathexis syndrome PubMed

Hemoglobinopathies

Beta thalassemia

• 2023: Saliba et al. How I treat non-transfusion-dependent β-thalassemia PubMed
• 2018: Taher & Cappellini. How I manage medical complications of β-thalassemia in adults PubMed

Sickle cell disease

• 2019: Stenger et al. How I treat sickle cell disease with hematopoietic cell transplantation
• 2018: Pirenne & Yazdanbakhsh. How I safely transfuse patients with sickle-cell disease and manage delayed hemolytic transfusion reactions PubMed
• 2018: Shet & Wun. How I diagnose and treat venous thromboembolism in sickle cell disease
• 2018: Thein & Howard. How I treat the older adult with sickle cell disease
• 2015: Anele et al. How I treat priapism PubMed
• 2015: Kassim et al. How I treat and manage strokes in sickle cell disease PubMed
• 2014: Sharpe & Thein. How I treat renal complications in sickle cell disease PubMed

Hemolytic disorders

• 2018: Machogu & Machado. How I treat hypoxia in adults with hemoglobinopathies and hemolytic disorders PubMed
• 2017: Go et al. How I treat autoimmune hemolytic anemia PubMed

Cold agglutinin disease (CAD)

• 2021: Berentsen. How I treat cold agglutinin disease

Atypical hemolytic uremic syndrome (aHUS)

• 2023: Fakhouri et al. How I diagnose and treat atypical hemolytic uremic syndrome PubMed
• 2014: Cataland & Wu. How I treat: the clinical differentiation and initial treatment of adult patients with atypical hemolytic uremic syndrome PubMed

Paroxysmal nocturnal hemoglobinuria (PNH)

• 2021: Brodsky. How I treat paroxysmal nocturnal hemoglobinuria
• 2009: Brodsky. How I treat paroxysmal nocturnal hemoglobinuria PubMed

Warm autoimmune hemolytic anemia (WAIHA)

• 2021: Barcellini & Fattizzo. How I treat warm autoimmune hemolytic anemia

Special considerations

Age-based recommendations

The majority of How I Treat articles focus on "standard" adults; below, articles that focus on other age populations are concatenated.

Neonates

• 2023: Stanworth & Mumford How I diagnose and treat neonatal thrombocytopenia PubMed
• 2018: Brown et al. How I treat infant leukemia PubMed

Children

• 2023: Myers et al. How I use risk factors for success or failure of CD19 CAR T cells to guide management of children and AYA with B-cell ALL PubMed
• 2023: Si Lim et al. How I treat newly diagnosed and refractory T-cell acute lymphoblastic lymphoma in children and young adults PubMed
• 2021: Rubnitz & Kaspers. How I treat pediatric acute myeloid leukemia PubMed
• 2020: Hunger & Raetz. How I treat relapsed acute lymphoblastic leukemia in the pediatric population PubMed
• 2020: Teachey & O'Connor How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children PubMed
• 2019: Hijiya & Suttorp. How I treat chronic myeloid leukemia in children and adolescents
• 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
• 2018: Locatelli & Strahm. How I treat myelodysplastic syndromes of childhood PubMed
• 2017: Young. How I treat pediatric venous thromboembolism PubMed
• 2012: Locatelli et al. How I treat relapsed childhood acute lymphoblastic leukemia PubMed

Adolescents and young adults (AYA)

• 2023: Si Lim et al. How I treat newly diagnosed and refractory T-cell acute lymphoblastic lymphoma in children and young adults PubMed
• 2019: Hijiya & Suttorp. How I treat chronic myeloid leukemia in children and adolescents
• 2019: Young. How I treat children with haemophilia and inhibitors
• 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
• 2015: Curran & Stock. How I treat acute lymphoblastic leukemia in older adolescents and young adults PubMed

Older adults

• 2023: Lugtenburg & Mutsaers How I treat older patients with DLBCL in the frontline setting PubMed
• 2019: Chan & Eikelbloom. How I manage anticoagulant therapy in older individuals with atrial fibrillation or venous thromboembolism
• 2018: Thein & Howard. How I treat the older adult with sickle cell disease
• 2014: Ossenkoppele & Löwenberg. How I treat the older patient with acute myeloid leukemia PubMed
• 2013: Gökbuget. How I treat older patients with ALL PubMed
• 2010: Mehta et al. How I treat elderly patients with myeloma PubMed

Complications of treatment

Bleeding

• 2017: Boonyawat et al. How I treat heavy menstrual bleeding associated with anticoagulants PubMed
• 2014: Schulman & Furie. How I treat poisoning with vitamin K antagonists PubMed
• 2014: Siegal et al. How I treat target-specific oral anticoagulant-associated bleeding PubMed

Cardiovascular complications

• 2022: Herrmann et al. How I treat cardiovascular complications in patients with lymphoid malignancies PubMed

Immune effector cells toxicity management

• 2023: Gutierrez et al. How I approach optimization of patients at risk of cardiac and pulmonary complications after CAR T-cell therapy PubMed
• 2023: Jain et al. How I treat refractory CRS and ICANS after CAR T-cell therapy PubMed
• 2023: Jain et al. How I treat cytopenias after CAR T-cell therapy PubMed
• 2023: Santomasso et al. How I treat unique and difficult-to-manage cases of CAR T-cell therapy-associated neurotoxicity PubMed
• 2020: Hill & Seo How I prevent infections in patients receiving CD19-targeted chimeric antigen receptor T cells for B-cell malignancies

Infectious complications

• 2023: Dadwal et al. How I prevent viral reactivation in high-risk patients PubMed
• 2022: El Chaer et al. How I treat and prevent COVID-19 in patients with hematologic malignancies and recipients of cellular therapies PubMed
• 2022: Law & Taplitz. How I manage infection risk and prevention in patients with lymphoid cancer PubMed
• 2020: Hill & Seo. How I prevent infections in patients receiving CD19-targeted chimeric antigen receptor T cells for B-cell malignancies
• 2016: El Chaer et al. How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients PubMed
• 2016: Waghmare et al. How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation PubMed
• 2014: Nucci & Anaissie. How we treat invasive fungal diseases in patients with acute leukemia: the importance of an individualized approach PubMed

Iron overload

• 2012: Hoffbrand et al. How I treat transfusional iron overload PubMed

Medication toxicities

• 2017: Delforge & Ludwig. How I manage the toxicities of myeloma drugs PubMed

Neurologic medications

• 2022: Nayak & Batchelor. How I treat neurologic complications in patients with lymphoid cancer PubMed

Genetic risk

• 2023: Hamilton et al. How I communicate with patients and families about germ line genetic information PubMed
• 2016: University of Chicago Hematopoietic Malignancies Cancer Risk Team How I diagnose and manage individuals at risk for inherited myeloid malignancies PubMed

Gynecologic considerations

Menstruation

• 2017: Boonyawat et al. How I treat heavy menstrual bleeding associated with anticoagulants PubMed

Pregnancy

• 2022: Fiore et al. How I manage pregnancy in women with Glanzmann thrombasthenia
• 2020: Dunleavy & McLintock. How I treat lymphoma in pregnancy
• 2020: Ferrari & Peyvandi. How I treat thrombotic thrombocytopenic purpura in pregnancy
• 2020: Leebeek et al. How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease
• 2020: Middeldorp & Ganzevoort. How I treat venous thromboembolism in pregnancy
• 2016: Achebe & Gafter-Gvili. How I treat anemia in pregnancy: iron, cobalamin, and folate PubMed
• 2013: Milojkovic & Apperley. How I treat leukemia during pregnancy PubMed
• 2012: Gernsheimer et al. How I treat thrombocytopenia in pregnancy PubMed

Postpartum period

• 2015: Pavord & Maybury. How I treat postpartum hemorrhage PubMed

Hospitalization

• 2023: Akpan & Hunt. How I approach the prevention and treatment of thrombotic complications in hospitalized patients PubMed
• 2023: Samuelson Bannow & Konkle. How I approach bleeding in hospitalized patients PubMed
• 2023: Zon & Berliner. How I manage inpatient consultations for quantitative neutrophil abnormalities in adults PubMed
• 2012: Dobromirski & Cohen. How I manage venous thromboembolism risk in hospitalized medical patients PubMed

Regional considerations

• 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed

Surgical considerations

• 2020: Shander et al. How I treat anemia in the perisurgical setting
• 2012: Spyropoulos & Douketis. How I treat anticoagulated patients undergoing an elective procedure or surgery PubMed

Transplantation

Allogeneic HSCT

• 2024: Mina et al. How I reduce and treat posttransplant relapse of MDS PubMed
• 2023: DeFilipp & Chen. How I treat with maintenance therapy after allogeneic HCT PubMed
• 2021: Burns & Morris. How I use allogeneic HSCT for adults with inborn errors of immunity PubMed
• 2020: Puerta-Alcalde et al. How I perform hematopoietic stem cell transplantation on patients with a history of invasive fungal disease PubMed
• 2019: McCurdy & Luznik. How we perform haploidentical stem cell transplantation with posttransplant cyclophosphamide PubMed
• 2018: Gribben. How and when I do allogeneic transplant in CLL PubMed
• 2017: Alvarnas et al. How I treat patients with HIV-related hematological malignancies using hematopoietic cell transplantation PubMed
• 2017: Williams. How I treat bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation PubMed
• 2016: El Chaer et al. How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients PubMed
• 2012: Wingard et al. How I manage pulmonary nodular lesions and nodular infiltrates in patients with hematologic malignancies or undergoing hematopoietic cell transplantation PubMed

Autologous HSCT

• 2014: Gertz & Dingli. How we manage autologous stem cell transplantation for patients with multiple myeloma PubMed

Graft versus host disease (GVHD)

• 2023: Cooper & Abkowitz. How I diagnose and treat acute graft-versus-host disease after solid organ transplantation
• 2023: Rimando et al. How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond
• 2020: Martin. How I treat steroid-refractory acute graft-versus-host disease PubMed
• 2019: Sarantopoulos et al. How I treat refractory chronic graft-versus-host disease
• 2016: McDonald. How I treat acute graft-versus-host disease of the gastrointestinal tract and the liver PubMed
• 2014: Flowers & Martin. How we treat chronic graft-versus-host disease
• 2012: Treister et al. How we treat oral chronic graft-versus-host disease PubMed
• 2007: Deeg. How I treat refractory acute GVHD PubMed

Miscellaneous

Atrial fibrillation

• 2016: Steinberg. How I use anticoagulation in atrial fibrillation PubMed

Cryoglobulinemia

• 2016: Muchtar et al. How I treat cryoglobulinemia PubMed

Immunodeficiency

Common variable immune deficiency (CVID)

• 2010: Cunningham-Rundles. How I treat common variable immune deficiency PubMed

Severe combined immunodeficiency (SCID)

• 2013: Gaspar et al. How I treat severe combined immunodeficiency PubMed

Priapism

• 2015: Anele et al. How I treat priapism PubMed

Protoporphyria

• 2023: Karp Leaf & Dickey. How I treat erythropoietic protoporphyria and X-linked protoporphyria PubMed

T-cell chronic active Epstein-Barr virus disease (CAEBV)

• 2018: Bollard & Cohen. How I treat T-cell chronic active Epstein-Barr virus disease PubMed