Difference between revisions of "Cisplatin (Platinol)"
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
| − | + | <div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | |
*[[Anal cancer]] | *[[Anal cancer]] | ||
| + | *[[Anaplastic large cell lymphoma]] | ||
*[[Basal cell and squamous cell skin cancer]] | *[[Basal cell and squamous cell skin cancer]] | ||
*[[Bladder cancer]] | *[[Bladder cancer]] | ||
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*[[Central nervous system (CNS) cancer]] | *[[Central nervous system (CNS) cancer]] | ||
*[[Cervical cancer]] | *[[Cervical cancer]] | ||
| + | *[[Diffuse large B-cell lymphoma]] | ||
*[[Esophageal cancer]] | *[[Esophageal cancer]] | ||
| + | *[[Extranodal NK/T-cell lymphoma, nasal type]] | ||
*[[Gastric cancer]] | *[[Gastric cancer]] | ||
*[[Head and neck cancer]] | *[[Head and neck cancer]] | ||
| Line 29: | Line 32: | ||
*[[Pancreatic cancer]] | *[[Pancreatic cancer]] | ||
*[[Penile cancer]] | *[[Penile cancer]] | ||
| + | *[[Peripheral T-cell lymphoma]] | ||
| + | *[[Primary mediastinal B-cell lymphoma]] | ||
*[[Small cell lung cancer]] | *[[Small cell lung cancer]] | ||
| − | |||
*[[Testicular cancer]] | *[[Testicular cancer]] | ||
*[[Thymoma]] | *[[Thymoma]] | ||
| + | *[[Transformed lymphoma]] | ||
*[[Unknown primary]] | *[[Unknown primary]] | ||
*[[Uterine cancer]] | *[[Uterine cancer]] | ||
| + | </div> | ||
==Patient drug information== | ==Patient drug information== | ||
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[[Category:Alkylating agents]] | [[Category:Alkylating agents]] | ||
| − | |||
[[Category:Anal cancer medications]] | [[Category:Anal cancer medications]] | ||
| + | [[Category:Anaplastic large cell lymphoma medications]] | ||
[[Category:Basal cell and squamous cell skin cancer medications]] | [[Category:Basal cell and squamous cell skin cancer medications]] | ||
[[Category:Bladder cancer medications]] | [[Category:Bladder cancer medications]] | ||
| Line 202: | Line 208: | ||
[[Category:Central nervous system (CNS) cancer medications]] | [[Category:Central nervous system (CNS) cancer medications]] | ||
[[Category:Cervical cancer medications]] | [[Category:Cervical cancer medications]] | ||
| + | [[Category:Diffuse large B-cell lymphoma medications]] | ||
[[Category:Esophageal cancer medications]] | [[Category:Esophageal cancer medications]] | ||
| + | [[Category:Extranodal NK/T-cell lymphoma, nasal type medications]] | ||
[[Category:Gastric cancer medications]] | [[Category:Gastric cancer medications]] | ||
[[Category:Head and neck cancer medications]] | [[Category:Head and neck cancer medications]] | ||
| Line 216: | Line 224: | ||
[[Category:Pancreatic cancer medications]] | [[Category:Pancreatic cancer medications]] | ||
[[Category:Penile cancer medications]] | [[Category:Penile cancer medications]] | ||
| + | [[Category:Peripheral T-cell lymphoma medications]] | ||
| + | [[Category:Primary mediastinal B-cell lymphoma medications]] | ||
[[Category:Small cell lung cancer medications]] | [[Category:Small cell lung cancer medications]] | ||
| − | |||
[[Category:Testicular cancer medications]] | [[Category:Testicular cancer medications]] | ||
[[Category:Thymoma medications]] | [[Category:Thymoma medications]] | ||
| + | [[Category:Transformed lymphoma medications]] | ||
[[Category:Uterine cancer medications]] | [[Category:Uterine cancer medications]] | ||
[[Category:Drugs FDA approved in 1978]] | [[Category:Drugs FDA approved in 1978]] | ||
Revision as of 01:32, 14 May 2015
General information
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.[1][2]
Route: IV, intracavitary (intraperitoneal)
Extravasation: vesicant (concentration ≥0.5 mg/mL)/irritant (concentration <0.5 mg/mL)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Anal cancer
- Anaplastic large cell lymphoma
- Basal cell and squamous cell skin cancer
- Bladder cancer
- Bone cancer
- Breast cancer
- Central nervous system (CNS) cancer
- Cervical cancer
- Diffuse large B-cell lymphoma
- Esophageal cancer
- Extranodal NK/T-cell lymphoma, nasal type
- Gastric cancer
- Head and neck cancer
- Hepatobiliary cancer
- Hodgkin lymphoma
- Mantle cell lymphoma
- Melanoma
- Mesothelioma
- Multiple myeloma
- Neuroendocrine tumors
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Penile cancer
- Peripheral T-cell lymphoma
- Primary mediastinal B-cell lymphoma
- Small cell lung cancer
- Testicular cancer
- Thymoma
- Transformed lymphoma
- Unknown primary
- Uterine cancer
Patient drug information
- Cisplatin (Platinol) patient drug information (Chemocare)[3]
- Cisplatin (Platinol) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 12/19/1978: Initial FDA approval
Also known as
| Synonyms | |||||||
|---|---|---|---|---|---|---|---|
| Abiplatin | Axiplat | Biocisplatinum | Bioplatino | Blastolem | Blastolem RU | Briplatin | Brisplatin |
| C-Platin | CDDP | Ceplatin | Ciplatan | Ciplexal | cis-diamminedichloroplatinum III | CIS-GRY | cis-platinum |
| Cismaplat | Cispatin | Cisplamerck | Cisplan | Cisplasol | Cisplatex | Cisplatin-AQ | Cisplatin-Ebewe I.A. |
| Cisplatin-Teva | Cisplatin Comp | Cisplatin DBL | Cisplatine | Cisplatin Ebewe | Cisplatine Cytosafe | Cisplatine Dakota | Cisplatine Merck |
| Cisplatine Teva | Cisplatin FOT | Cisplatin Hexal | Cisplatin Lederle | Cisplatin Lens | Cisplatin Maruko | Cisplatin Mayne | Cisplatin NC |
| Cisplatino | Cisplatino Almirall | Cisplatino Asofarm | Cisplatino Deltafarma | Cisplatino Ferrer | Cisplatino Gador | Cisplatino Labinca | Cisplatino Martian |
| Cisplatino Microsules | Cisplatino Pharmacia | Cisplatino Teva | Cisplatin Pharmachemie | Cisplatin Pharmacia | Cisplatin Sandoz | Cisplatin Sanofi-Synthelabo | Cisplatin Solution |
| Cisplatinum | Cisplatyl | Cisteen | Citoplatino | Cytoplatin | Cytoplatin-AQ | DACP | DDP |
| Docistin | Elvecis | Fauldcispla | IA COR | Ifapla | JIN Shun | Kemoplat | Lederplatin |
| Lyoph.cisplatin | Metaplatin | Neoplat | Neoplatin | Nippon Kayaku Cisplatin | Noveldexis | NSC 119875 | NUO XIN |
| Oncoplatin AQ | P&U Cisplatin | Placis | Platamin | Platamine | Platamine RTU | Platiblastin | Platiblastin-S |
| Platicis | Platidiam | Platikem | Platil | Platimit | Platin | Platinil | Platino II Filaxis |
| Platinol | Platinol AQ | Platinox | Platinoxan | platinum | Platiran | Platistil | Platistin |
| Platistine | Platosin | Pronto Platamine | Randa | Romcis | Shun KE DA | Sicatem | Sinplatin |
| Sisplanil | Tecnoplatin | Tisplal | Trav Cisplatin | Unistin | |||
References
Categories:
- Drug index
- Chemotherapy
- Intravenous chemotherapy
- Intracavitary chemotherapy
- Vesicant chemotherapy
- Irritant chemotherapy
- Platinum agents
- Alkylating agents
- Anal cancer medications
- Anaplastic large cell lymphoma medications
- Basal cell and squamous cell skin cancer medications
- Bladder cancer medications
- Bone cancer medications
- Breast cancer medications
- Cancer of unknown primary medications
- Central nervous system (CNS) cancer medications
- Cervical cancer medications
- Diffuse large B-cell lymphoma medications
- Esophageal cancer medications
- Extranodal NK/T-cell lymphoma, nasal type medications
- Gastric cancer medications
- Head and neck cancer medications
- Hepatobiliary cancer medications
- Hodgkin lymphoma medications
- Mantle cell lymphoma medications
- Melanoma medications
- Mesothelioma medications
- Multiple myeloma medications
- Neuroendocrine tumor medications
- Non-small cell lung cancer medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Penile cancer medications
- Peripheral T-cell lymphoma medications
- Primary mediastinal B-cell lymphoma medications
- Small cell lung cancer medications
- Testicular cancer medications
- Thymoma medications
- Transformed lymphoma medications
- Uterine cancer medications
- Drugs FDA approved in 1978