Difference between revisions of "Cisplatin (Platinol)"
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*[[Anaplastic large cell lymphoma]] | *[[Anaplastic large cell lymphoma]] | ||
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*[[Bladder cancer]] | *[[Bladder cancer]] | ||
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[[Category:Anal cancer medications]] | [[Category:Anal cancer medications]] | ||
[[Category:Anaplastic large cell lymphoma medications]] | [[Category:Anaplastic large cell lymphoma medications]] | ||
| − | [[Category:Basal cell | + | [[Category:Basal cell carcinoma (BCC) medications]] |
[[Category:Bladder cancer medications]] | [[Category:Bladder cancer medications]] | ||
[[Category:Bone sarcoma medications]] | [[Category:Bone sarcoma medications]] | ||
Revision as of 15:30, 3 December 2017
General information
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.[1][2]
Route: IV, intracavitary (intraperitoneal)
Extravasation: vesicant (concentration ≥0.5 mg/mL)/irritant (concentration <0.5 mg/mL)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Anal cancer
- Anaplastic large cell lymphoma
- Basal cell carcinoma (BCC)
- Bladder cancer
- Bone sarcoma
- Breast cancer
- Central nervous system (CNS) cancer
- Cervical cancer
- Diffuse large B-cell lymphoma
- Esophageal cancer
- Extranodal NK/T-cell lymphoma, nasal type
- Gastric cancer
- Head and neck cancer
- Hepatobiliary cancer
- Hodgkin lymphoma
- Mantle cell lymphoma
- Melanoma
- Mesothelioma
- Multiple myeloma
- Neuroendocrine tumors
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Penile cancer
- Peripheral T-cell lymphoma
- Primary mediastinal B-cell lymphoma
- Small cell lung cancer
- Testicular cancer
- Thymoma
- Transformed lymphoma
- Unknown primary
- Uterine cancer
Patient drug information
- Cisplatin (Platinol) patient drug information (Chemocare)[3]
- Cisplatin (Platinol) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 12/19/1978: Initial FDA approval
Also known as
| Synonyms | |||||||
|---|---|---|---|---|---|---|---|
| Abiplatin | Axiplat | Biocisplatinum | Bioplatino | Blastolem | Blastolem RU | Briplatin | Brisplatin |
| C-Platin | CDDP | Ceplatin | Ciplatan | Ciplexal | cis-diamminedichloroplatinum III | CIS-GRY | cis-platinum |
| Cismaplat | Cispatin | Cisplamerck | Cisplan | Cisplasol | Cisplatex | Cisplatin-AQ | Cisplatin-Ebewe I.A. |
| Cisplatin-Teva | Cisplatin Comp | Cisplatin DBL | Cisplatine | Cisplatin Ebewe | Cisplatine Cytosafe | Cisplatine Dakota | Cisplatine Merck |
| Cisplatine Teva | Cisplatin FOT | Cisplatin Hexal | Cisplatin Lederle | Cisplatin Lens | Cisplatin Maruko | Cisplatin Mayne | Cisplatin NC |
| Cisplatino | Cisplatino Almirall | Cisplatino Asofarm | Cisplatino Deltafarma | Cisplatino Ferrer | Cisplatino Gador | Cisplatino Labinca | Cisplatino Martian |
| Cisplatino Microsules | Cisplatino Pharmacia | Cisplatino Teva | Cisplatin Pharmachemie | Cisplatin Pharmacia | Cisplatin Sandoz | Cisplatin Sanofi-Synthelabo | Cisplatin Solution |
| Cisplatinum | Cisplatyl | Cisteen | Citoplatino | Cytoplatin | Cytoplatin-AQ | DACP | DDP |
| Docistin | Elvecis | Fauldcispla | IA COR | Ifapla | JIN Shun | Kemoplat | Lederplatin |
| Lyoph.cisplatin | Metaplatin | Neoplat | Neoplatin | Nippon Kayaku Cisplatin | Noveldexis | NSC 119875 | NUO XIN |
| Oncoplatin AQ | P&U Cisplatin | Placis | Platamin | Platamine | Platamine RTU | Platiblastin | Platiblastin-S |
| Platicis | Platidiam | Platikem | Platil | Platimit | Platin | Platinil | Platino II Filaxis |
| Platinol | Platinol AQ | Platinox | Platinoxan | platinum | Platiran | Platistil | Platistin |
| Platistine | Platosin | Pronto Platamine | Randa | Romcis | Shun KE DA | Sicatem | Sinplatin |
| Sisplanil | Tecnoplatin | Tisplal | Trav Cisplatin | Unistin | |||
References
Categories:
- Drug index
- Intravenous medications
- Intracavitary medications
- Vesicant chemotherapy
- Irritant chemotherapy
- Platinum agents
- Alkylating agents
- Anal cancer medications
- Anaplastic large cell lymphoma medications
- Basal cell carcinoma (BCC) medications
- Bladder cancer medications
- Bone sarcoma medications
- Breast cancer medications
- Cancer of unknown primary medications
- Central nervous system (CNS) cancer medications
- Cervical cancer medications
- Diffuse large B-cell lymphoma medications
- Esophageal cancer medications
- Extranodal NK/T-cell lymphoma, nasal type medications
- Gastric cancer medications
- Head and neck cancer medications
- Hepatobiliary cancer medications
- Hodgkin lymphoma medications
- Mantle cell lymphoma medications
- Melanoma medications
- Mesothelioma medications
- Multiple myeloma medications
- Neuroendocrine tumor medications
- Non-small cell lung cancer medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Penile cancer medications
- Peripheral T-cell lymphoma medications
- Primary mediastinal B-cell lymphoma medications
- Small cell lung cancer medications
- Testicular cancer medications
- Thymoma medications
- Transformed lymphoma medications
- Uterine cancer medications
- Drugs FDA approved in 1978
- WHO Essential Cancer Medicine