Bone sarcoma

Section editor
	Elizabeth J. Davis, MD Vanderbilt University Nashville, TN ejdavis25

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Note: this page is for subtype-nonspecific bone sarcoma regimens, and some subtypes with very few subtype-specific regimens. Please see the category page for links to other sarcoma types or use one of these links:

• Ewing sarcoma
• Giant-cell tumor of bone
• Osteosarcoma

Guidelines

ESMO/EURACAN/GENTURIS/PaedCan

• 2021: Strauss et al. Bone sarcomas: ESMO–EURACAN–GENTURIS–ERN PaedCan Clinical Practice Guideline for diagnosis, treatment and follow-up

Older

• 2018: Casali et al. Bone sarcomas: ESMO-PaedCan-EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up
• 2014: Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

NCCN

• NCCN Guidelines - Bone Cancer

Chondrosarcoma, all lines of therapy

• No standard chemotherapy for grades 1 to 3 conventional chondrosarcoma
• Mesenchymal chondrosarcoma has been treated with Ewing's sarcoma regimens
• Dedifferentiated chondrosarcoma has been treated with osteosarcoma regimens

Undifferentiated pleomorphic sarcoma (UPS) of bone, all lines of therapy

• Undifferentiated pleomorphic sarcoma (UPS) of bone has been treated with osteosarcoma regimens