Difference between revisions of "How I Treat"
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*'''2014:''' Nucci & Anaissie. [https://doi.org/10.1182/blood-2014-04-516211 How we treat invasive fungal diseases in patients with acute leukemia: the importance of an individualized approach] [https://pubmed.ncbi.nlm.nih.gov/25339358/ PubMed] | *'''2014:''' Nucci & Anaissie. [https://doi.org/10.1182/blood-2014-04-516211 How we treat invasive fungal diseases in patients with acute leukemia: the importance of an individualized approach] [https://pubmed.ncbi.nlm.nih.gov/25339358/ PubMed] | ||
+ | ==Genetic risk== | ||
+ | *'''2016:''' University of Chicago Hematopoietic Malignancies Cancer Risk Team [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5813725/ How I diagnose and manage individuals at risk for inherited myeloid malignancies] [https://pubmed.ncbi.nlm.nih.gov/27471235/ PubMed] | ||
==Pregnancy== | ==Pregnancy== | ||
*'''2022:''' Fiore et al. [https://doi.org/10.1182/blood.2021011595 How I manage pregnancy in women with Glanzmann thrombasthenia] | *'''2022:''' Fiore et al. [https://doi.org/10.1182/blood.2021011595 How I manage pregnancy in women with Glanzmann thrombasthenia] |
Revision as of 19:41, 21 September 2023
The "How I Treat" series has been published by Blood for several decades and covers a wide variety of topics in malignant and classical hematology. While these articles are not considered to be formal guidelines, they are considered highly reputable sources of expert opinion. They cover topics ranging from commonly encountered hematologic conditions with a large evidence base, to very rare conditions with only case reports to guide treatment. The purpose of this page is to consolidate the links to all known published How I Treat articles.
In the first two sections (malignant hematology and classical hematology), articles are presented by condition, in reverse chronological order. In the third section, articles are gathered under "special considerations" such as pregnancy and hematologic disease. Given the rapid change in evidence in many areas of hematology, readers are encouraged to consider any article published 5+ years ago to be for historical purposes, only.
Note: this page is currently under construction.
Malignant hematology
Myeloid neoplasms
Acute lymphoblastic leukemia (ALL)
- 2023: Kopmar & Cassaday. How I prevent and treat central nervous system disease in adults with acute lymphoblastic leukemia PubMed
- 2023: Myers et al. How I use risk factors for success or failure of CD19 CAR T cells to guide management of children and AYA with B-cell ALL PubMed
- 2023: Si Lim et al. How I treat newly diagnosed and refractory T-cell acute lymphoblastic lymphoma in children and young adults PubMed
- 2020: Aldoss & Douer. How I treat the toxicities of pegasparaginase in adults with acute lymphoblastic leukemia PubMed
- 2020: Aldoss & Forman. How I treat adults with advanced acute lymphoblastic leukemia eligible for CD19-targeted immunotherapy PubMed
- 2020: Hunger & Raetz. How I treat relapsed acute lymphoblastic leukemia in the pediatric population PubMed
- 2020: Teachey & O'Connor How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children PubMed
- 2019: Ravandi. How I treat Philadelphia chromosome-positive acute lymphoblastic leukemia PubMed
- 2015: Curran & Stock. How I treat acute lymphoblastic leukemia in older adolescents and young adults PubMed
- 2015: Frey & Luger. How I treat adults with relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia PubMed
- 2013: Gökbuget. How I treat older patients with ALL PubMed
- 2012: Locatelli et al. How I treat relapsed childhood acute lymphoblastic leukemia PubMed
- 2007: Rowe & Goldstone. How I treat acute lymphocytic leukemia in adults PubMed
Acute myeloid leukemia (AML)
- 2023: Biederstädt & Rezvani. How I treat high-risk acute myeloid leukemia using preemptive adoptive cellular immunotherapy PubMed
- 2021: Falini et al. How I diagnose and treat NPM1-mutated AML PubMed
- 2021: Rubnitz & Kaspers. How I treat pediatric acute myeloid leukemia PubMed
- 2020: DeWolf & Tallman. How I treat relapsed or refractory AML PubMed
- 2020: DiNardo & Wei. How I treat acute myeloid leukemia in the era of new drugs PubMed
- 2016: Ofran et al. How I treat acute myeloid leukemia presenting with preexisting comorbidities PubMed
- 2016: Pratz & Levis. How I treat FLT3-mutated AML PubMed
- 2015: Röllig & Ehninger. How I treat hyperleukocytosis in acute myeloid leukemia PubMed
- 2014: Ossenkoppele & Löwenberg. How I treat the older patient with acute myeloid leukemia PubMed
- 2011: Bakst et al. How I treat extramedullary acute myeloid leukemia PubMed
Acute promyelocytic leukemia (APL)
- 2014: Sanz & Motesinos. How we prevent and treat differentiation syndrome in patients with acute promyelocytic leukemia PubMed
- 2009: Tallman & Altman. How I treat acute promyelocytic leukemia PubMed
Chronic myeloid leukemia (CML)
- 2022: Berman. How I treat chronic-phase chronic myelogenous leukemia
- 2019: Hijiya & Suttorp. How I treat chronic myeloid leukemia in children and adolescents
- 2016: Gotlib. How I treat atypical chronic myeloid leukemia PubMed
- 2012: Cortes & Kantarjian. How I treat newly diagnosed chronic phase CML PubMed
- 2009: Radich. How I monitor residual disease in chronic myeloid leukemia PubMed
Chronic myelomonocytic leukemia (CMML)
- 2017: Solary & Itzykson. How I treat chronic myelomonocytic leukemia PubMed
Essential thrombocythemia (ET)
- 2016: Rumi & Cazzola. How I treat essential thrombocythemia PubMed
Myelodysplastic syndrome (MDS)
- 2019: Santini How I treat MDS after hypomethylating agent failure
- 2013: Sekeres & Cutler How we treat higher-risk myelodysplastic syndromes PubMed
- 2013: Fenaux & Adès How we treat lower-risk myelodysplastic syndromes
Polycythemia vera (PV)
- 2014: Vannucchi How I treat polycythemia vera PubMed
Lymphoid neoplasms
Adult T-cell leukemia-lymphoma (ATLL)
- 2021: Cook & Phillips How I treat adult T-cell leukemia/lymphoma PubMed
Anaplastic large cell lymphoma
- 2018: Metha-Shah et al. How I treat breast implant-associated anaplastic large cell lymphoma PubMed
Burkitt lymphoma (BL)
- 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
- 2014: Jacobson & LaCasce. How I treat Burkitt lymphoma in adults PubMed
Castleman disease
Chronic lymphocytic leukemia (CLL/SLL)
- 2021: Lew et al. How I treat chronic lymphocytic leukemia after venetoclax
- 2019: Stephens & Byrd. How I manage ibrutinib intolerance and complications in patients with chronic lymphocytic leukemia
- 2018: Brown. How I treat CLL patients with ibrutinib PubMed
- 2018: Gribben. How and when I do allogeneic transplant in CLL PubMed
- 2017: Woyach. How I manage ibrutinib-refractory chronic lymphocytic leukemia PubMed
- 2009: Gribben. How I treat CLL up front PubMed
Classical Hodgkin lymphoma (cHL)
- 2021: Epperla & Herrera. How I incorporate novel agents into the treatment of classical Hodgkin lymphoma
- 2015: Alinari & Blum. How I treat relapsed classical Hodgkin lymphoma after autologous stem cell transplant PubMed
- 2014: Uldrick & Little. How I treat classical Hodgkin lymphoma in patients infected with human immunodeficiency virus PubMed
CNS lymphoma
- 2017: Chin & Cheah. How I treat patients with aggressive lymphoma at high risk of CNS relapse PubMed
- 2013: Rubenstein et al. How I treat CNS lymphomas PubMed
Cutaneous T-cell lymphoma (CTCL)
- 2019: Shinohara & Shustov How I treat primary cutaneous CD30 + lymphoproliferative disorders
Diffuse large B-cell lymphoma (DLBCL)
- 2023: Lugtenburg & Mutsaers. How I treat older patients with DLBCL in the frontline setting PubMed
Follicular lymphoma (FL)
- 2019: Casulo & Barr. How I treat early-relapsing follicular lymphoma PubMed
High-grade B-cell lymphoma (HGBL)
- 2017: Friedberg. How I treat double-hit lymphoma PubMed
HIV-associated lymphoma
- 2014: Uldrick & Little. How I treat classical Hodgkin lymphoma in patients infected with human immunodeficiency virus PubMed
- 2012: Dunleavy & Wilson. How I treat HIV-associated lymphoma PubMed
- 2010: Bower. How I treat HIV-associated multicentric Castleman disease PubMed
Large granular lymphocytic leukemia (T-LGL)
- 2011: Lamy & Loughran. How I treat LGL leukemia PubMed
NK- and T-cell lymphoma
- 2013: Tse & Kwong. How I treat NK/T-cell lymphomas PubMed
Nodular lymphocyte-predominant Hodgkin lymphoma (NLP-HL)
- 2020: Eichenauer & Engert. How I treat nodular lymphocyte-predominant Hodgkin Lymphoma
Prolymphocytic leukemia (T-PLL)
- 2012: Dearden. How I treat prolymphocytic leukemia PubMed
Waldenström macroglobulinemia (WM)
- 2019: Dimopoulos & Kastritis. How I treat Waldenström macroglobulinemia PubMed
Plasma cell dyscrasias
Light-chain (AL) amyloidosis
- 2022: Palladini & Merlini. How I treat AL amyloidosis
- 2012: Leung et al. How I treat amyloidosis: the importance of accurate diagnosis and amyloid typing PubMed
Multiple myeloma
- 2023: van de Donk. How We Manage Newly Diagnosed Multiple Myeloma With Circulating Tumor Cells
- 2022: Zamagni et al. How I treat high-risk multiple myeloma
- 2022: Kastritis et al. How I treat relapsed multiple myeloma
- 2022: Vaxman & Gertz. How I approach smoldering multiple myeloma
Histiocytic disorders
Hemophagocytic lymphohistiocytosis (HLH)
- 2015: Schram & Berliner. How I treat hemophagocytic lymphohistiocytosis in the adult patient PubMed
Classical hematology
Hemostasis and thrombosis
Acquired thrombotic thrombocytopenic purpura (aTTP)
- 2022: Akwaa et al. How I treat immune-mediated thrombotic thrombocytopenic purpura after hospital discharge
- 2020: Ferrari & Peyvandi. How I treat thrombotic thrombocytopenic purpura in pregnancy
Antiphospholipid antibody syndrome (APS)
- 2021: Cohen & Isenberg. How I treat anticoagulant-refractory thrombotic antiphospholipid syndrome PubMed
Arterial thromboembolism (ATE)
- 2020: May & Moll. How I treat unexplained arterial thrombosis
Hemophilia
- 2020: Leebeek et al. How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease
- 2019: Young. How I treat children with haemophilia and inhibitors
Thrombotic microangiopathy (TMA)
- 2023: Doreille et al. How I treat thrombotic microangiopathy in the era of rapid genomics
- 2021: Thomas & Scully. How I treat microangiopathic hemolytic anemia in patients with cancer
Venous thromboembolism (VTE)
- 2022: Schmidt & Lee. How I treat and prevent venous thrombotic complications in patients with lymphoma
- 2020: Klok & Huisman. How I assess and manage the risk of bleeding in patients treated for venous thromboembolism
- 2020: Middeldorp & Ganzevoort. How I treat venous thromboembolism in pregnancy
- 2020: Wang & Carrier. How I treat obese patients with oral anticoagulants
- 2019: Pabinger & Thaler. How I treat patients with hereditary antithrombin deficiency
- 2019: Chan & Eikelbloom. How I manage anticoagulant therapy in older individuals with atrial fibrillation or venous thromboembolism
- 2019: Kraaijpoel & Carrier. How I treat cancer-associated venous thromboembolism
- 2018: Shet & Wun. How I diagnose and treat venous thromboembolism in sickle cell disease
von Willebrand disease (vWD)
- 2020: Biguzzi et al. How I treat gastrointestinal bleeding in congenital and acquired von Willebrand disease
- 2020: Leebeek et al. How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease
- 2019: Lavin & O'Donnell. How I treat low von Willebrand factor levels
Cytopenias
Anemia
- 2021: Gurnari & Maciejewski. How I manage acquired pure red cell aplasia in adults
- 2020: Anand & Gupta. How I treat anemia in heart failure
- 2020: Fishbane & Coyne. How I treat renal anemia
- 2020: Gilreath & Rodgers. How I treat cancer-associated anemia
- 2020: Shander et al. How I treat anemia in the perisurgical setting
- 2014: Hershko & Camaschella. How I treat unexplained refractory iron deficiency anemia
Autoimmune cytopenia
- 2022: Porpaczy & Jäger. How I manage autoimmune cytopenias in patients with lymphoid cancer PubMed
Immune thrombocytopenia (ITP)
- 2021: Ghanima et al. How I treat primary ITP in adult patients who are unresponsive to or dependent on corticosteroid treatment
Thrombocytopenia and platelet dysfunction
- 2023: Stanworth & Mumford How I diagnose and treat neonatal thrombocytopenia PubMed
- 2022: Stanworth & Shah How I use platelet transfusions PubMed
- 2022: Fiore et al. How I manage pregnancy in women with Glanzmann thrombasthenia
- 2021: Kyrle & Eichinger How I manage cyclic thrombocytopenia
Hemoglobinopathies
Beta thalassemia
- 2018: Taher & Cappellini. How I manage medical complications of β-thalassemia in adults PubMed
Sickle cell disease
- 2019: Stenger et al. How I treat sickle cell disease with hematopoietic cell transplantation
- 2018: Shet & Wun. How I diagnose and treat venous thromboembolism in sickle cell disease
- 2018: Thein & Howard. How I treat the older adult with sickle cell disease
Hemolytic disorders
Cold agglutinin disease (CAD)
- 2021: Berentsen. How I treat cold agglutinin disease
Atypical hemolytic uremic syndrome (aHUS)
- 2023: Fakhouri et al. How I diagnose and treat atypical hemolytic uremic syndrome PubMed
Paroxysmal nocturnal hemoglobinuria (PNH)
- 2021: Brodsky. How I treat paroxysmal nocturnal hemoglobinuria
Warm autoimmune hemolytic anemia (WAIHA)
- 2021: Barcellini & Fattizzo. How I treat warm autoimmune hemolytic anemia
Special considerations
Age-based recommendations
The majority of How I Treat articles focus on "standard" adults; below, articles that focus on other age populations are concatenated.
Neonates
- 2023: Stanworth & Mumford How I diagnose and treat neonatal thrombocytopenia PubMed
- 2018: Brown et al. How I treat infant leukemia PubMed
Children
- 2023: Myers et al. How I use risk factors for success or failure of CD19 CAR T cells to guide management of children and AYA with B-cell ALL PubMed
- 2023: Si Lim et al. How I treat newly diagnosed and refractory T-cell acute lymphoblastic lymphoma in children and young adults PubMed
- 2020: Teachey & O'Connor How I treat newly diagnosed T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma in children PubMed
- 2019: Hijiya & Suttorp. How I treat chronic myeloid leukemia in children and adolescents
- 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
- 2012: Locatelli et al. How I treat relapsed childhood acute lymphoblastic leukemia PubMed
Adolescents and young adults (AYA)
- 2023: Si Lim et al. How I treat newly diagnosed and refractory T-cell acute lymphoblastic lymphoma in children and young adults PubMed
- 2019: Hijiya & Suttorp. How I treat chronic myeloid leukemia in children and adolescents
- 2019: Young. How I treat children with haemophilia and inhibitors
- 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
- 2015: Curran & Stock. How I treat acute lymphoblastic leukemia in older adolescents and young adults PubMed
Older adults
- 2023: Lugtenburg & Mutsaers How I treat older patients with DLBCL in the frontline setting PubMed
- 2019: Chan & Eikelbloom. How I manage anticoagulant therapy in older individuals with atrial fibrillation or venous thromboembolism
- 2018: Thein & Howard. How I treat the older adult with sickle cell disease
- 2014: Ossenkoppele & Löwenberg. How I treat the older patient with acute myeloid leukemia PubMed
- 2013: Gökbuget. How I treat older patients with ALL PubMed
Complications of treatment
Immune effector cells toxicity management
- 2023: Gutierrez et al. How I approach optimization of patients at risk of cardiac and pulmonary complications after CAR T-cell therapy PubMed
- 2023: Jain et al. How I treat refractory CRS and ICANS after CAR T-cell therapy PubMed
- 2023: Jain et al. How I treat cytopenias after CAR T-cell therapy PubMed
- 2023: Santomasso et al. How I treat unique and difficult-to-manage cases of CAR T-cell therapy-associated neurotoxicity PubMed
Infectious complications
- 2016: El Chaer et al. How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients PubMed
- 2016: Waghmare et al. How I treat respiratory viral infections in the setting of intensive chemotherapy or hematopoietic cell transplantation PubMed
- 2014: Nucci & Anaissie. How we treat invasive fungal diseases in patients with acute leukemia: the importance of an individualized approach PubMed
Genetic risk
- 2016: University of Chicago Hematopoietic Malignancies Cancer Risk Team How I diagnose and manage individuals at risk for inherited myeloid malignancies PubMed
Pregnancy
- 2022: Fiore et al. How I manage pregnancy in women with Glanzmann thrombasthenia
- 2020: Ferrari & Peyvandi. How I treat thrombotic thrombocytopenic purpura in pregnancy
- 2020: Leebeek et al. How I manage pregnancy in carriers of hemophilia and patients with von Willebrand disease
- 2020: Middeldorp & Ganzevoort. How I treat venous thromboembolism in pregnancy
Regional considerations
- 2018: Gopal & Gross. How I treat Burkitt lymphoma in children, adolescents, and young adults in sub-Saharan Africa PubMed
Transplatation
Allogeneic HSCT
- 2023: DeFilipp & Chen. How I treat with maintenance therapy after allogeneic HCT PubMed
- 2020: Puerta-Alcalde et al. How I perform hematopoietic stem cell transplantation on patients with a history of invasive fungal disease PubMed
- 2019: McCurdy & Luznik. How we perform haploidentical stem cell transplantation with posttransplant cyclophosphamide PubMed
- 2018: Gribben. How and when I do allogeneic transplant in CLL PubMed
- 2017: Alvarnas et al. How I treat patients with HIV-related hematological malignancies using hematopoietic cell transplantation PubMed
- 2017: Williams. How I treat bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation PubMed
- 2016: El Chaer et al. How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients PubMed
- 2012: Wingard et al. How I manage pulmonary nodular lesions and nodular infiltrates in patients with hematologic malignancies or undergoing hematopoietic cell transplantation PubMed
Graft versus host disease (GVHD)
- 2023: Cooper & Abkowitz. How I diagnose and treat acute graft-versus-host disease after solid organ transplantation
- 2023: Rimando et al. How I prevent GVHD in high-risk patients: posttransplant cyclophosphamide and beyond
- 2020: Martin. How I treat steroid-refractory acute graft-versus-host disease PubMed
- 2019: Sarantopoulos et al. How I treat refractory chronic graft-versus-host disease
- 2016: McDonald. How I treat acute graft-versus-host disease of the gastrointestinal tract and the liver PubMed
- 2014: Flowers & Martin. How we treat chronic graft-versus-host disease
- 2012: Treister et al. How we treat oral chronic graft-versus-host disease PubMed
- 2007: Deeg. How I treat refractory acute GVHD PubMed