Difference between revisions of "Cisplatin (Platinol)"
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| Line 27: | Line 27: | ||
*[[Mesothelioma]] | *[[Mesothelioma]] | ||
*[[Multiple myeloma]] | *[[Multiple myeloma]] | ||
| + | *[[Nasopharyngeal carcinoma]] | ||
*[[Neuroendocrine tumors]] | *[[Neuroendocrine tumors]] | ||
*[[Non-small cell lung cancer]] | *[[Non-small cell lung cancer]] | ||
| Line 50: | Line 51: | ||
==Also known as== | ==Also known as== | ||
| + | *'''Code name:''' NSC 119875 | ||
| + | *'''Generic names:''' CDDP, cis-diamminedichloroplatinum III, cis-platinum, cisplatinum, DACP, DDP | ||
| + | *'''Brand names:''' | ||
{| border="1" style="text-align:center;" | {| border="1" style="text-align:center;" | ||
!colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | !colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | ||
| Line 58: | Line 62: | ||
|Bioplatino | |Bioplatino | ||
|Blastolem | |Blastolem | ||
| − | |||
|Briplatin | |Briplatin | ||
|Brisplatin | |Brisplatin | ||
| + | |C-Platin | ||
|- | |- | ||
| − | |||
| − | |||
|Ceplatin | |Ceplatin | ||
|Ciplatan | |Ciplatan | ||
|Ciplexal | |Ciplexal | ||
| − | | | + | |Cis-GRY |
| − | |||
| − | |||
| − | |||
|Cismaplat | |Cismaplat | ||
|Cispatin | |Cispatin | ||
|Cisplamerck | |Cisplamerck | ||
|Cisplan | |Cisplan | ||
| + | |- | ||
|Cisplasol | |Cisplasol | ||
|Cisplatex | |Cisplatex | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
|Cisplatine | |Cisplatine | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
|Cisplatino | |Cisplatino | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
|Cisplatyl | |Cisplatyl | ||
|Cisteen | |Cisteen | ||
|Citoplatino | |Citoplatino | ||
|Cytoplatin | |Cytoplatin | ||
| − | |||
| − | |||
| − | |||
|- | |- | ||
|Docistin | |Docistin | ||
|Elvecis | |Elvecis | ||
|Fauldcispla | |Fauldcispla | ||
| − | |||
|Ifapla | |Ifapla | ||
| − | |||
|Kemoplat | |Kemoplat | ||
|Lederplatin | |Lederplatin | ||
| − | |||
| − | |||
|Metaplatin | |Metaplatin | ||
|Neoplat | |Neoplat | ||
| + | |- | ||
|Neoplatin | |Neoplatin | ||
| − | |||
|Noveldexis | |Noveldexis | ||
| − | |||
| − | |||
| − | |||
|Oncoplatin AQ | |Oncoplatin AQ | ||
| − | |||
|Placis | |Placis | ||
|Platamin | |Platamin | ||
|Platamine | |Platamine | ||
| − | |||
|Platiblastin | |Platiblastin | ||
| − | | | + | |Platicis |
|- | |- | ||
| − | |||
|Platidiam | |Platidiam | ||
|Platikem | |Platikem | ||
| Line 151: | Line 109: | ||
|Platinil | |Platinil | ||
|Platino II Filaxis | |Platino II Filaxis | ||
| + | |Platinol | ||
|- | |- | ||
| − | |||
| − | |||
|Platinox | |Platinox | ||
|Platinoxan | |Platinoxan | ||
| − | |||
|Platiran | |Platiran | ||
|Platistil | |Platistil | ||
|Platistin | |Platistin | ||
| − | |||
|Platistine | |Platistine | ||
|Platosin | |Platosin | ||
| − | |||
|Randa | |Randa | ||
| + | |- | ||
|Romcis | |Romcis | ||
| − | |||
|Sicatem | |Sicatem | ||
|Sinplatin | |Sinplatin | ||
| − | |||
|Sisplanil | |Sisplanil | ||
|Tecnoplatin | |Tecnoplatin | ||
|Tisplal | |Tisplal | ||
| − | |||
|Unistin | |Unistin | ||
|} | |} | ||
| Line 209: | Line 161: | ||
[[Category:Mesothelioma medications]] | [[Category:Mesothelioma medications]] | ||
[[Category:Multiple myeloma medications]] | [[Category:Multiple myeloma medications]] | ||
| + | [[Category:Nasopharyngeal carcinoma medications]] | ||
[[Category:Neuroendocrine tumor medications]] | [[Category:Neuroendocrine tumor medications]] | ||
[[Category:Non-small cell lung cancer medications]] | [[Category:Non-small cell lung cancer medications]] | ||
Revision as of 18:38, 21 January 2018
General information
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.[1][2]
Route: IV, intracavitary (intraperitoneal)
Extravasation: vesicant (concentration ≥0.5 mg/mL)/irritant (concentration <0.5 mg/mL)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Anal cancer
- Anaplastic large cell lymphoma
- Basal cell carcinoma (BCC)
- Bladder cancer
- Bone sarcoma
- Breast cancer
- Cervical cancer
- Diffuse large B-cell lymphoma
- Esophageal cancer
- Extranodal NK/T-cell lymphoma, nasal type
- Gastric cancer
- Head and neck cancer
- Hepatobiliary cancer
- Hodgkin lymphoma
- Low-grade glioma
- Mantle cell lymphoma
- Melanoma
- Mesothelioma
- Multiple myeloma
- Nasopharyngeal carcinoma
- Neuroendocrine tumors
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Penile cancer
- Peripheral T-cell lymphoma
- Primary mediastinal B-cell lymphoma
- Small cell lung cancer
- Testicular cancer
- Thymoma
- Transformed lymphoma
- Unknown primary
- Uterine cancer
Patient drug information
- Cisplatin (Platinol) patient drug information (Chemocare)[3]
- Cisplatin (Platinol) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 12/19/1978: Initial FDA approval
Also known as
- Code name: NSC 119875
- Generic names: CDDP, cis-diamminedichloroplatinum III, cis-platinum, cisplatinum, DACP, DDP
- Brand names:
| Synonyms | |||||||
|---|---|---|---|---|---|---|---|
| Abiplatin | Axiplat | Biocisplatinum | Bioplatino | Blastolem | Briplatin | Brisplatin | C-Platin |
| Ceplatin | Ciplatan | Ciplexal | Cis-GRY | Cismaplat | Cispatin | Cisplamerck | Cisplan |
| Cisplasol | Cisplatex | Cisplatine | Cisplatino | Cisplatyl | Cisteen | Citoplatino | Cytoplatin |
| Docistin | Elvecis | Fauldcispla | Ifapla | Kemoplat | Lederplatin | Metaplatin | Neoplat |
| Neoplatin | Noveldexis | Oncoplatin AQ | Placis | Platamin | Platamine | Platiblastin | Platicis |
| Platidiam | Platikem | Platil | Platimit | Platin | Platinil | Platino II Filaxis | Platinol |
| Platinox | Platinoxan | Platiran | Platistil | Platistin | Platistine | Platosin | Randa |
| Romcis | Sicatem | Sinplatin | Sisplanil | Tecnoplatin | Tisplal | Unistin | |
References
Categories:
- Drug index
- Intravenous medications
- Intracavitary medications
- Vesicant chemotherapy
- Irritant chemotherapy
- Platinum agents
- Alkylating agents
- Anal cancer medications
- Anaplastic large cell lymphoma medications
- Basal cell carcinoma (BCC) medications
- Bladder cancer medications
- Bone sarcoma medications
- Breast cancer medications
- Cancer of unknown primary medications
- Cervical cancer medications
- Diffuse large B-cell lymphoma medications
- Esophageal cancer medications
- Extranodal NK/T-cell lymphoma, nasal type medications
- Gastric cancer medications
- Head and neck cancer medications
- Hepatobiliary cancer medications
- Hodgkin lymphoma medications
- Low-grade glioma medications
- Mantle cell lymphoma medications
- Melanoma medications
- Mesothelioma medications
- Multiple myeloma medications
- Nasopharyngeal carcinoma medications
- Neuroendocrine tumor medications
- Non-small cell lung cancer medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Penile cancer medications
- Peripheral T-cell lymphoma medications
- Primary mediastinal B-cell lymphoma medications
- Small cell lung cancer medications
- Testicular cancer medications
- Thymoma medications
- Transformed lymphoma medications
- Uterine cancer medications
- Drugs FDA approved in 1978
- WHO Essential Cancer Medicine