Difference between revisions of "Cisplatin (Platinol)"
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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
+ | |||
+ | ==Diseases for which it is used== | ||
+ | *[[Aggressive Non-Hodgkin lymphoma]] | ||
+ | *[[Anal cancer]] | ||
+ | *[[Basal cell and squamous cell skin cancer]] | ||
+ | *[[Bladder cancer]] | ||
+ | *[[Bone cancer]] | ||
+ | *[[Breast cancer]] | ||
+ | *[[Central nervous system (CNS) cancer]] | ||
+ | *[[Cervical cancer]] | ||
+ | *[[Esophageal cancer]] | ||
+ | *[[Gastric cancer]] | ||
+ | *[[Head and neck cancer]] | ||
+ | *[[Hepatobiliary cancer]] | ||
+ | *[[Hodgkin lymphoma]] | ||
+ | *[[Mantle cell lymphoma]] | ||
+ | *[[Melanoma]] | ||
+ | *[[Mesothelioma]] | ||
+ | *[[Multiple myeloma]] | ||
+ | *[[Neuroendocrine tumors]] | ||
+ | *[[Non-small cell lung cancer]] | ||
+ | *[[Ovarian cancer]] | ||
+ | *[[Pancreatic cancer]] | ||
+ | *[[Penile cancer]] | ||
+ | *[[Small cell lung cancer]] | ||
+ | *[[T-cell lymphoma]] | ||
+ | *[[Testicular cancer]] | ||
+ | *[[Thymoma]] | ||
+ | *[[Unknown primary]] | ||
+ | *[[Uterine cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
*[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]</ref> | ||
+ | |||
+ | ==History of changes in FDA indication== | ||
+ | * 12/19/1978: Initial FDA approval | ||
==Also known as== | ==Also known as== | ||
Line 185: | Line 218: | ||
[[Category:Thymoma medications]] | [[Category:Thymoma medications]] | ||
[[Category:Uterine cancer medications]] | [[Category:Uterine cancer medications]] | ||
+ | |||
+ | [[Category:Drugs FDA approved in 1978]] |
Revision as of 15:30, 7 November 2014
General information
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.[1][2]
Route: IV
Extravasation: vesicant (concentration ≥0.5 mg/mL)/irritant (concentration <0.5 mg/mL)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Aggressive Non-Hodgkin lymphoma
- Anal cancer
- Basal cell and squamous cell skin cancer
- Bladder cancer
- Bone cancer
- Breast cancer
- Central nervous system (CNS) cancer
- Cervical cancer
- Esophageal cancer
- Gastric cancer
- Head and neck cancer
- Hepatobiliary cancer
- Hodgkin lymphoma
- Mantle cell lymphoma
- Melanoma
- Mesothelioma
- Multiple myeloma
- Neuroendocrine tumors
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Penile cancer
- Small cell lung cancer
- T-cell lymphoma
- Testicular cancer
- Thymoma
- Unknown primary
- Uterine cancer
Patient drug information
- Cisplatin (Platinol) patient drug information (Chemocare)[3]
- Cisplatin (Platinol) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 12/19/1978: Initial FDA approval
Also known as
Synonyms | |||||||
---|---|---|---|---|---|---|---|
Abiplatin | Axiplat | Biocisplatinum | Bioplatino | Blastolem | Blastolem RU | Briplatin | Brisplatin |
C-Platin | CDDP | Ceplatin | Ciplatan | Ciplexal | cis-diamminedichloroplatinum III | CIS-GRY | cis-platinum |
Cismaplat | Cispatin | Cisplamerck | Cisplan | Cisplasol | Cisplatex | Cisplatin-AQ | Cisplatin-Ebewe I.A. |
Cisplatin-Teva | Cisplatin Comp | Cisplatin DBL | Cisplatine | Cisplatin Ebewe | Cisplatine Cytosafe | Cisplatine Dakota | Cisplatine Merck |
Cisplatine Teva | Cisplatin FOT | Cisplatin Hexal | Cisplatin Lederle | Cisplatin Lens | Cisplatin Maruko | Cisplatin Mayne | Cisplatin NC |
Cisplatino | Cisplatino Almirall | Cisplatino Asofarm | Cisplatino Deltafarma | Cisplatino Ferrer | Cisplatino Gador | Cisplatino Labinca | Cisplatino Martian |
Cisplatino Microsules | Cisplatino Pharmacia | Cisplatino Teva | Cisplatin Pharmachemie | Cisplatin Pharmacia | Cisplatin Sandoz | Cisplatin Sanofi-Synthelabo | Cisplatin Solution |
Cisplatinum | Cisplatyl | Cisteen | Citoplatino | Cytoplatin | Cytoplatin-AQ | DACP | DDP |
Docistin | Elvecis | Fauldcispla | IA COR | Ifapla | JIN Shun | Kemoplat | Lederplatin |
Lyoph.cisplatin | Metaplatin | Neoplat | Neoplatin | Nippon Kayaku Cisplatin | Noveldexis | NSC 119875 | NUO XIN |
Oncoplatin AQ | P&U Cisplatin | Placis | Platamin | Platamine | Platamine RTU | Platiblastin | Platiblastin-S |
Platicis | Platidiam | Platikem | Platil | Platimit | Platin | Platinil | Platino II Filaxis |
Platinol | Platinol AQ | Platinox | Platinoxan | platinum | Platiran | Platistil | Platistin |
Platistine | Platosin | Pronto Platamine | Randa | Romcis | Shun KE DA | Sicatem | Sinplatin |
Sisplanil | Tecnoplatin | Tisplal | Trav Cisplatin | Unistin |
References
Categories:
- Drug index
- Chemotherapy
- Platinum agents
- Alkylating agents
- Vesicant chemotherapy
- Irritant chemotherapy
- Aggressive Non-Hodgkin lymphoma medications
- Anal cancer medications
- Basal cell and squamous cell skin cancer medications
- Bladder cancer medications
- Bone cancer medications
- Breast cancer medications
- Cancer of unknown primary medications
- Central nervous system (CNS) cancer medications
- Cervical cancer medications
- Esophageal cancer medications
- Gastric cancer medications
- Head and neck cancer medications
- Hepatobiliary cancer medications
- Hodgkin lymphoma medications
- Mantle cell lymphoma medications
- Melanoma medications
- Mesothelioma medications
- Multiple myeloma medications
- Neuroendocrine tumor medications
- Non-small cell lung cancer medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Penile cancer medications
- Small cell lung cancer medications
- T-cell lymphoma medications
- Testicular cancer medications
- Thymoma medications
- Uterine cancer medications
- Drugs FDA approved in 1978