Difference between revisions of "Cisplatin (Platinol)"
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==General information== | ==General information== | ||
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.<ref name="insert">[http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018057s080lbl.pdf Cisplatin (Platinol) package insert]</ref><ref>[[Media:Cisplatin.pdf | Cisplatin (Platinol) package insert (locally hosted backup)]]</ref> | Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.<ref name="insert">[http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/018057s080lbl.pdf Cisplatin (Platinol) package insert]</ref><ref>[[Media:Cisplatin.pdf | Cisplatin (Platinol) package insert (locally hosted backup)]]</ref> | ||
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*[[Bladder cancer]] | *[[Bladder cancer]] | ||
*[[Bone cancer]] | *[[Bone cancer]] | ||
| + | *[[Breast cancer]] | ||
*[[Cervical cancer]] | *[[Cervical cancer]] | ||
*[[Esophageal cancer]] | *[[Esophageal cancer]] | ||
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*[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/cisplatin.aspx Cisplatin (Platinol) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/cisplatin-patient-drug-information Cisplatin (Platinol) patient drug information (UpToDate)]</ref> | ||
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| + | ==Also known as== | ||
| + | Abiplatin, Axiplat, Biocisplatinum, Bioplatino, Blastolem, Blastolem RU, Briplatin, Brisplatin, C-Platin, CDDP, Ceplatin, Ciplatan, Ciplexal, cis-diamminedichloroplatinum III, CIS-GRY, cis-platinum, Cismaplat, Cispatin, Cisplamerck, Cisplan, Cisplasol, Cisplatex, Cisplatin, Cisplatin-AQ, Cisplatin-Ebewe I.A., Cisplatin-Teva, Cisplatin Comp, Cisplatin DBL, Cisplatine, Cisplatin Ebewe, Cisplatine Cytosafe, Cisplatine Dakota, Cisplatine Merck, Cisplatine Teva, Cisplatin FOT, Cisplatin Hexal, Cisplatin Lederle, Cisplatin Lens, Cisplatin Maruko, Cisplatin Mayne, Cisplatin NC, Cisplatino, Cisplatino Almirall, Cisplatino Asofarm, Cisplatino Deltafarma, Cisplatino Ferrer, Cisplatino Gador, Cisplatino Labinca, Cisplatino Martian, Cisplatino Microsules, Cisplatino Pharmacia, Cisplatino Teva, Cisplatin Pharmachemie, Cisplatin Pharmacia, Cisplatin Sandoz, Cisplatin Sanofi-Synthelabo, Cisplatin Solution, Cisplatinum, Cisplatyl, Cisteen, Citoplatino, Cytoplatin, Cytoplatin-AQ, DACP, DDP, Docistin, Elvecis, Fauldcispla, IA COR, Ifapla, JIN Shun, Kemoplat, Lederplatin, Lyoph.cisplatin, Metaplatin, Neoplat, Neoplatin, Nippon Kayaku Cisplatin, Noveldexis, NSC 119875, NUO XIN, Oncoplatin AQ, P&U Cisplatin, Placis, Platamin, Platamine, Platamine RTU, Platiblastin, Platiblastin-S, Platicis, Platidiam, Platikem, Platil, Platimit, Platin, Platinil, Platino II Filaxis, Platinol, Platinol AQ, Platinox, Platinoxan, platinum, Platiran, Platistil, Platistin, Platistine, Platosin, Pronto Platamine, Randa, Romcis, Shun KE DA, Sicatem, Sinplatin, Sisplanil, Tecnoplatin, Tisplal, Trav Cisplatin, or Unistin. | ||
==References== | ==References== | ||
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[[Category:Bladder cancer medications]] | [[Category:Bladder cancer medications]] | ||
[[Category:Bone cancer medications]] | [[Category:Bone cancer medications]] | ||
| + | [[Category:Breast cancer medications]] | ||
[[Category:Cancer of unknown primary medications]] | [[Category:Cancer of unknown primary medications]] | ||
[[Category:Cervical cancer medications]] | [[Category:Cervical cancer medications]] | ||
Revision as of 05:43, 2 April 2013
General information
Class/mechanism: Platinum analog, alkylating-like, producing predominantly interstrand DNA crosslinks that are cell-cycle nonspecific.[1][2]
Route: IV
Extravasation: vesicant (concentration >=0.5 mg/mL)/irritant (concentration <0.5 mg/mL)
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Anal cancer
- Basal cell and squamous cell skin cancer
- Bladder cancer
- Bone cancer
- Breast cancer
- Cervical cancer
- Esophageal cancer
- Gastric cancer
- Hepatobiliary cancer
- Hodgkin lymphoma
- Melanoma
- Mesothelioma
- Multiple myeloma
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Small cell lung cancer
- Testicular cancer
- Thymoma
- Unknown primary
- Uterine cancer
Patient drug information
- Cisplatin (Platinol) patient drug information (Chemocare)[3]
- Cisplatin (Platinol) patient drug information (UpToDate)[4]
Also known as
Abiplatin, Axiplat, Biocisplatinum, Bioplatino, Blastolem, Blastolem RU, Briplatin, Brisplatin, C-Platin, CDDP, Ceplatin, Ciplatan, Ciplexal, cis-diamminedichloroplatinum III, CIS-GRY, cis-platinum, Cismaplat, Cispatin, Cisplamerck, Cisplan, Cisplasol, Cisplatex, Cisplatin, Cisplatin-AQ, Cisplatin-Ebewe I.A., Cisplatin-Teva, Cisplatin Comp, Cisplatin DBL, Cisplatine, Cisplatin Ebewe, Cisplatine Cytosafe, Cisplatine Dakota, Cisplatine Merck, Cisplatine Teva, Cisplatin FOT, Cisplatin Hexal, Cisplatin Lederle, Cisplatin Lens, Cisplatin Maruko, Cisplatin Mayne, Cisplatin NC, Cisplatino, Cisplatino Almirall, Cisplatino Asofarm, Cisplatino Deltafarma, Cisplatino Ferrer, Cisplatino Gador, Cisplatino Labinca, Cisplatino Martian, Cisplatino Microsules, Cisplatino Pharmacia, Cisplatino Teva, Cisplatin Pharmachemie, Cisplatin Pharmacia, Cisplatin Sandoz, Cisplatin Sanofi-Synthelabo, Cisplatin Solution, Cisplatinum, Cisplatyl, Cisteen, Citoplatino, Cytoplatin, Cytoplatin-AQ, DACP, DDP, Docistin, Elvecis, Fauldcispla, IA COR, Ifapla, JIN Shun, Kemoplat, Lederplatin, Lyoph.cisplatin, Metaplatin, Neoplat, Neoplatin, Nippon Kayaku Cisplatin, Noveldexis, NSC 119875, NUO XIN, Oncoplatin AQ, P&U Cisplatin, Placis, Platamin, Platamine, Platamine RTU, Platiblastin, Platiblastin-S, Platicis, Platidiam, Platikem, Platil, Platimit, Platin, Platinil, Platino II Filaxis, Platinol, Platinol AQ, Platinox, Platinoxan, platinum, Platiran, Platistil, Platistin, Platistine, Platosin, Pronto Platamine, Randa, Romcis, Shun KE DA, Sicatem, Sinplatin, Sisplanil, Tecnoplatin, Tisplal, Trav Cisplatin, or Unistin.
References
- Drug index
- Chemotherapy
- Platinum agents
- Alkylating agents
- Vesicant chemotherapy
- Irritant chemotherapy
- Anal cancer medications
- Basal cell and squamous cell skin cancer medications
- Bladder cancer medications
- Bone cancer medications
- Breast cancer medications
- Cancer of unknown primary medications
- Cervical cancer medications
- Esophageal cancer medications
- Gastric cancer medications
- Hepatobiliary cancer medications
- Hodgkin lymphoma medications
- Melanoma medications
- Mesothelioma medications
- Multiple myeloma medications
- Non-small cell lung cancer medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Small cell lung cancer medications
- Testicular cancer medications
- Thymoma medications
- Uterine cancer medications