Difference between revisions of "Dexamethasone (Decadron)"
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Warner-admin (talk | contribs) m (Text replacement - "please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [https://online.lexi.com/lco/action/login UpToDate Lexidrug], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information" to "please refer to your preferred pharmacopeias or the prescribing information") |
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==General information== | ==General information== | ||
− | Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, [[Antiemesis|antiemetic properties]], and anti-inflammatory effects.<ref name="insert">[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]</ref><ref>[[ | + | Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, [[Antiemesis|antiemetic properties]], and anti-inflammatory effects.<ref name="insert">[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]</ref><ref>[[:File:Dexamethasone.pdf | Dexamethasone (Decadron) package insert (locally hosted backup)]]</ref> |
<br>Route: PO, IV, IM | <br>Route: PO, IV, IM | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
Line 6: | Line 6: | ||
*[[Steroid conversions]] | *[[Steroid conversions]] | ||
− | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information.<ref name="insert"></ref> |
+ | |||
+ | ==Diseases for which it is established ''(work in progress)''== | ||
+ | *[[Peripheral T-cell lymphoma]] | ||
+ | |||
+ | ==Diseases for which it is used== | ||
+ | <div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | ||
+ | *[[Anaplastic large cell lymphoma]] | ||
+ | *[[B-cell acute lymphoblastic leukemia]] | ||
+ | *[[Burkitt lymphoma]] | ||
+ | *[[CNS lymphoma]] | ||
+ | *[[Diffuse large B-cell lymphoma]] | ||
+ | *[[Extranodal NK- and T-cell lymphoma, nasal type]] | ||
+ | *[[Follicular lymphoma]] | ||
+ | *[[Hemophagocytic lymphohistiocytosis]] | ||
+ | *[[HIV-associated lymphoma]] | ||
+ | *[[Classical Hodgkin lymphoma]] | ||
+ | *[[Immune thrombocytopenia (ITP)]] | ||
+ | *[[Light-chain (AL) amyloidosis]] | ||
+ | *[[Mantle cell lymphoma]] | ||
+ | *[[Multiple myeloma]] | ||
+ | *[[NK- and T-cell lymphoma]] | ||
+ | *[[Plasma cell leukemia]] | ||
+ | *[[POEMS syndrome]] | ||
+ | *[[Primary mediastinal B-cell lymphoma]] | ||
+ | *[[Smoldering multiple myeloma]] | ||
+ | *[[T-cell acute lymphoblastic leukemia]] | ||
+ | *[[Transformed lymphoma]] | ||
+ | *[[Waldenström macroglobulinemia]] | ||
+ | </div> | ||
+ | |||
+ | ==Diseases for which it was used== | ||
+ | *[[Acute myeloid leukemia - historical|Acute myeloid leukemia]] | ||
+ | *[[Prostate cancer - historical|Prostate cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
− | *[http://chemocare.com/ | + | *[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]<ref name="insert"></ref> |
+ | *[https://chemocare.com/druginfo/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]<ref>[https://chemocare.com/druginfo/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]</ref> | ||
+ | |||
+ | ==History of changes in EMA indication== | ||
+ | *1952-01-01: EURD | ||
+ | ==History of changes in PMDA indication== | ||
+ | *2010-06-18: New additional indication and a new dosage for the treatment of [[multiple myeloma]]. | ||
+ | *2021-08-25: New indication and a new dosage for the treatment of [[Light-chain (AL) amyloidosis|systemic AL amyloidosis]]. | ||
==Also known as== | ==Also known as== | ||
− | + | *'''Generic names:''' dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate | |
− | + | *'''Brand names:''' | |
− | + | {| class="wikitable" style="text-align:center;" | |
− | |||
− | |||
− | {| | ||
!colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | !colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | ||
|- | |- | ||
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|Apidex | |Apidex | ||
|- | |- | ||
− | |||
|Arcodexan | |Arcodexan | ||
|Auxiloson | |Auxiloson | ||
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|Bexine | |Bexine | ||
|Beyonas Dexa | |Beyonas Dexa | ||
+ | |Bisuo DS | ||
|- | |- | ||
− | |||
|Brulin | |Brulin | ||
|Bucokon | |Bucokon | ||
Line 56: | Line 92: | ||
|Carbidu | |Carbidu | ||
|Carulon | |Carulon | ||
+ | |Cebedex | ||
|- | |- | ||
− | |||
|Cellacort | |Cellacort | ||
|Celudex | |Celudex | ||
Line 65: | Line 101: | ||
|Corson | |Corson | ||
|Corsona | |Corsona | ||
+ | |Corsone | ||
|- | |- | ||
− | |||
|Corsum | |Corsum | ||
|Corticoidex | |Corticoidex | ||
Line 74: | Line 110: | ||
|Cortitop | |Cortitop | ||
|Coyensu | |Coyensu | ||
+ | |D-Cort | ||
|- | |- | ||
− | |||
|Dacrosone | |Dacrosone | ||
|Daidoron | |Daidoron | ||
|Dalalone | |Dalalone | ||
− | |||
− | |||
|Danason | |Danason | ||
|Danasone | |Danasone | ||
− | |||
|Daxilone | |Daxilone | ||
|Decacin | |Decacin | ||
|Decaderm | |Decaderm | ||
+ | |- | ||
|Decadolone | |Decadolone | ||
|Decadran | |Decadran | ||
− | |||
|Decadron | |Decadron | ||
− | |||
− | |||
− | |||
− | |||
|Decadronal | |Decadronal | ||
|Decadronfosfat | |Decadronfosfat | ||
− | |||
− | |||
− | |||
|Deca Forte | |Deca Forte | ||
− | |||
|Decafos | |Decafos | ||
|Decalin | |Decalin | ||
+ | |- | ||
|Decalon | |Decalon | ||
|Decalona | |Decalona | ||
Line 110: | Line 136: | ||
|Decaron | |Decaron | ||
|Decason | |Decason | ||
− | |||
|Decasone | |Decasone | ||
− | |||
|Decaspray | |Decaspray | ||
+ | |- | ||
|Decazol | |Decazol | ||
|Decdak | |Decdak | ||
Line 119: | Line 144: | ||
|Decicort | |Decicort | ||
|Decilone | |Decilone | ||
− | |||
|Decobel | |Decobel | ||
|Decolite | |Decolite | ||
|Decone | |Decone | ||
+ | |- | ||
|Decordex | |Decordex | ||
|Decorex | |Decorex | ||
Line 128: | Line 153: | ||
|Decorten | |Decorten | ||
|Dectan | |Dectan | ||
− | |||
− | |||
− | |||
|Dectancyl | |Dectancyl | ||
|Deexa | |Deexa | ||
|Deflaren | |Deflaren | ||
+ | |- | ||
|Dekesu | |Dekesu | ||
|Dekisachosei | |Dekisachosei | ||
|Dekort | |Dekort | ||
− | |||
|Deksa | |Deksa | ||
|Deksalon | |Deksalon | ||
Line 143: | Line 165: | ||
|Dellamethasone | |Dellamethasone | ||
|Deltafluorene | |Deltafluorene | ||
+ | |- | ||
|Demasone | |Demasone | ||
|Demeson | |Demeson | ||
|Dermadex | |Dermadex | ||
− | |||
|Dermidron | |Dermidron | ||
|Deronil | |Deronil | ||
Line 152: | Line 174: | ||
|Derson | |Derson | ||
|Dersone | |Dersone | ||
+ | |- | ||
|Desalark | |Desalark | ||
|Desametasone Fosf | |Desametasone Fosf | ||
|Desason | |Desason | ||
− | |||
|Deson | |Deson | ||
|Detametazon | |Detametazon | ||
Line 161: | Line 183: | ||
|Dethamedin | |Dethamedin | ||
|Dexa | |Dexa | ||
− | |||
− | |||
− | |||
|- | |- | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
|Dexabene | |Dexabene | ||
|Dexabeta | |Dexabeta | ||
− | |||
|Dexacen-4 | |Dexacen-4 | ||
− | |||
|Dexacilin | |Dexacilin | ||
|Dexacip | |Dexacip | ||
Line 181: | Line 192: | ||
|Dexacollyre | |Dexacollyre | ||
|Dexacom | |Dexacom | ||
+ | |- | ||
|Dexacort | |Dexacort | ||
− | |||
|Dexacortal | |Dexacortal | ||
|Dexacortin | |Dexacortin | ||
Line 190: | Line 201: | ||
|Dexacron | |Dexacron | ||
|Dexacutis | |Dexacutis | ||
+ | |- | ||
|Dexaden | |Dexaden | ||
− | |||
|Dexaderm | |Dexaderm | ||
|Dexaderme | |Dexaderme | ||
|Dexadermil | |Dexadermil | ||
|Dexadon | |Dexadon | ||
− | |||
|Dexadrol | |Dexadrol | ||
|Dexadron | |Dexadron | ||
Line 203: | Line 213: | ||
|Dexafar | |Dexafar | ||
|Dexafarm | |Dexafarm | ||
− | |||
|Dexaflam | |Dexaflam | ||
− | |||
|Dexaflan | |Dexaflan | ||
|Dexagalen | |Dexagalen | ||
|Dexagee | |Dexagee | ||
− | |||
|Dexagel | |Dexagel | ||
|Dexagenta | |Dexagenta | ||
+ | |- | ||
|Dexaglos | |Dexaglos | ||
|Dexagreen | |Dexagreen | ||
Line 218: | Line 226: | ||
|Dexaleniens | |Dexaleniens | ||
|Dexalocal | |Dexalocal | ||
− | |||
− | |||
|Dexaltin | |Dexaltin | ||
|Dexam | |Dexam | ||
+ | |- | ||
|Dexamag | |Dexamag | ||
|Dexamark | |Dexamark | ||
Line 227: | Line 234: | ||
|Dexamecortin | |Dexamecortin | ||
|Dexamedis | |Dexamedis | ||
− | |||
− | |||
|Dexamedix | |Dexamedix | ||
|Dexamedron | |Dexamedron | ||
|Dexameral | |Dexameral | ||
+ | |- | ||
|Dexameson | |Dexameson | ||
|Dexamesone | |Dexamesone | ||
|Dexamet | |Dexamet | ||
|Dexametason | |Dexametason | ||
− | |||
|Dexametasona | |Dexametasona | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
|Dexametax | |Dexametax | ||
|Dexametazon | |Dexametazon | ||
|Dexametazona | |Dexametazona | ||
+ | |- | ||
|Dexameth | |Dexameth | ||
|Dexamethason | |Dexamethason | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
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− | |||
− | |||
− | |||
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− | |||
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− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
|Dexamethasonum | |Dexamethasonum | ||
|Dexamethazon | |Dexamethazon | ||
Line 316: | Line 255: | ||
|Dexametisona | |Dexametisona | ||
|Dexametonal | |Dexametonal | ||
+ | |- | ||
|Dexametrat | |Dexametrat | ||
− | |||
|Dexamex | |Dexamex | ||
|Dexamil | |Dexamil | ||
Line 325: | Line 264: | ||
|Dexamonozon N | |Dexamonozon N | ||
|Dexanel | |Dexanel | ||
− | |||
|- | |- | ||
+ | |Dexan | ||
|Dexanil | |Dexanil | ||
− | |||
|Dexano | |Dexano | ||
− | |||
− | |||
|Dexaphos | |Dexaphos | ||
|Dexapolcort | |Dexapolcort | ||
|Dexapro | |Dexapro | ||
− | |||
− | |||
− | |||
|Dexaril | |Dexaril | ||
|Dexaroid | |Dexaroid | ||
+ | |- | ||
|Dexaron | |Dexaron | ||
|Dexart | |Dexart | ||
− | |||
|Dexasin | |Dexasin | ||
− | |||
|Dexasine | |Dexasine | ||
|Dexasol | |Dexasol | ||
Line 350: | Line 282: | ||
|Dexason | |Dexason | ||
|Dexasone | |Dexasone | ||
+ | |- | ||
|Dexasonlin | |Dexasonlin | ||
|Dexatab | |Dexatab | ||
|Dexaton | |Dexaton | ||
− | |||
|Dexatop | |Dexatop | ||
|Dexatotal | |Dexatotal | ||
|Dexaval | |Dexaval | ||
− | |||
|Dexaven | |Dexaven | ||
|Dexavet | |Dexavet | ||
− | | | + | |- |
|Dexawal | |Dexawal | ||
− | |||
|Dexawieb | |Dexawieb | ||
|Dexazen | |Dexazen | ||
Line 370: | Line 300: | ||
|Dexin | |Dexin | ||
|Dexinga | |Dexinga | ||
+ | |- | ||
|Dexion | |Dexion | ||
− | |||
|Dexmene | |Dexmene | ||
|Dexmesone | |Dexmesone | ||
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|Dexmethasone | |Dexmethasone | ||
|Dexmethsone | |Dexmethsone | ||
− | |||
|Dexona | |Dexona | ||
|Dexone | |Dexone | ||
Line 386: | Line 315: | ||
|Dexsol | |Dexsol | ||
|Dexstar | |Dexstar | ||
− | |||
|Dextason | |Dextason | ||
− | |||
− | |||
|Dexthasol | |Dexthasol | ||
− | |||
|Dexton | |Dexton | ||
+ | |- | ||
|Dextrasone | |Dextrasone | ||
|Dicorsone | |Dicorsone | ||
Line 398: | Line 324: | ||
|Diometa | |Diometa | ||
|Dison | |Dison | ||
− | + | |DM Solone | |
− | |DM Solone | ||
− | |||
− | |||
|Donray | |Donray | ||
|Dorison | |Dorison | ||
+ | |- | ||
|Doronil | |Doronil | ||
|Drenex | |Drenex | ||
|Drxaline | |Drxaline | ||
− | |||
|Elixirmethasone | |Elixirmethasone | ||
|Epidexone | |Epidexone | ||
Line 413: | Line 336: | ||
|Erladexone | |Erladexone | ||
|Ermethasone | |Ermethasone | ||
+ | |- | ||
|ETA Cortilen | |ETA Cortilen | ||
|Etason | |Etason | ||
|Euromethasone | |Euromethasone | ||
− | |||
|Fada Dexametasona | |Fada Dexametasona | ||
|Fadametasona | |Fadametasona | ||
Line 422: | Line 345: | ||
|Fexadron | |Fexadron | ||
|Fortecortin | |Fortecortin | ||
− | | | + | |- |
|Fosfato Dissodico Dexametasona | |Fosfato Dissodico Dexametasona | ||
|Gammacorten | |Gammacorten | ||
− | |||
|Gemisona | |Gemisona | ||
|Glymesason | |Glymesason | ||
Line 431: | Line 353: | ||
|Hexadecadrol | |Hexadecadrol | ||
|Hexadrol | |Hexadrol | ||
− | |||
|HI-Methasone | |HI-Methasone | ||
+ | |- | ||
|Hopamethasone | |Hopamethasone | ||
− | |||
|Idizone | |Idizone | ||
|Indexon | |Indexon | ||
Line 440: | Line 361: | ||
|Irzamethazone | |Irzamethazone | ||
|Isodexam | |Isodexam | ||
− | |Isopto | + | |Isopto |
− | | | + | |Kaarmepakkaus |
− | |||
|- | |- | ||
− | |||
|Kalmethasone | |Kalmethasone | ||
|Kanadex | |Kanadex | ||
Line 452: | Line 371: | ||
|Lanadexon | |Lanadexon | ||
|Licoson | |Licoson | ||
+ | |Limethason | ||
|- | |- | ||
− | |||
− | |||
|Lipotalon | |Lipotalon | ||
|Lisoderme | |Lisoderme | ||
Line 461: | Line 379: | ||
|Lokalison-F | |Lokalison-F | ||
|Lormine | |Lormine | ||
− | |||
|Loverine | |Loverine | ||
|Lupidexa | |Lupidexa | ||
+ | |- | ||
|Luxazone | |Luxazone | ||
|Maradex | |Maradex | ||
− | |Maxidex | + | |Maxidex |
|Mecoxon | |Mecoxon | ||
|Medesone | |Medesone | ||
|Medexasone | |Medexasone | ||
− | |||
|Mediamethasone | |Mediamethasone | ||
|Medicort | |Medicort | ||
+ | |- | ||
|Medidex | |Medidex | ||
|Megacort | |Megacort | ||
Line 479: | Line 397: | ||
|Mephamesona | |Mephamesona | ||
|Mephamesone | |Mephamesone | ||
− | |||
|Mephamesone-4 | |Mephamesone-4 | ||
|Meradexon | |Meradexon | ||
+ | |- | ||
|Merideca | |Merideca | ||
− | |Mesadoron | + | |Mesadoron |
− | |||
|Metalexina | |Metalexina | ||
|Metasolon | |Metasolon | ||
|Metax | |Metax | ||
− | |||
|Metaxon | |Metaxon | ||
|Metcort | |Metcort | ||
|Methaderm | |Methaderm | ||
+ | |- | ||
|Methasone | |Methasone | ||
|Mexasone | |Mexasone | ||
|Mexaton | |Mexaton | ||
− | |||
|Migradexan | |Migradexan | ||
− | |||
|Millicorten | |Millicorten | ||
|Minidex | |Minidex | ||
− | |||
|Mitasone | |Mitasone | ||
|Molacort | |Molacort | ||
− | | | + | |- |
|Mycidex | |Mycidex | ||
|Neodex | |Neodex | ||
− | |||
|Nexadron | |Nexadron | ||
− | |||
|Nodevex | |Nodevex | ||
|Nufadex M | |Nufadex M | ||
Line 514: | Line 426: | ||
|Ocudex | |Ocudex | ||
|Oftadek | |Oftadek | ||
+ | |- | ||
|Oftadex | |Oftadex | ||
− | |||
− | |||
− | |||
|Omedexon | |Omedexon | ||
|Onadron | |Onadron | ||
Line 524: | Line 434: | ||
|Opticort | |Opticort | ||
|Orazone | |Orazone | ||
+ | |Ordex | ||
|- | |- | ||
− | |||
|Orgadrone | |Orgadrone | ||
− | |||
|Penatone | |Penatone | ||
|Penodex | |Penodex | ||
Line 533: | Line 442: | ||
|Pidexon | |Pidexon | ||
|Plavex | |Plavex | ||
− | |||
|Plidexa | |Plidexa | ||
− | |||
|Prodexon | |Prodexon | ||
+ | |- | ||
|Pyderma | |Pyderma | ||
|Pyradexon | |Pyradexon | ||
Line 542: | Line 450: | ||
|Randexa | |Randexa | ||
|Redexon | |Redexon | ||
− | |||
|Rednisone | |Rednisone | ||
|Reusan | |Reusan | ||
|Rocolone | |Rocolone | ||
+ | |- | ||
|Ronic | |Ronic | ||
|Roximeth | |Roximeth | ||
|Rupedex | |Rupedex | ||
− | |||
− | |||
− | |||
|Santeson | |Santeson | ||
|Sawasone | |Sawasone | ||
Line 557: | Line 462: | ||
|Selftison | |Selftison | ||
|Shirodex | |Shirodex | ||
+ | |- | ||
|Shuayan | |Shuayan | ||
|Smile | |Smile | ||
|Solcort | |Solcort | ||
− | |||
|Soldesam | |Soldesam | ||
− | |||
|Soldesanil | |Soldesanil | ||
|Soldex | |Soldex | ||
|Soludecadron | |Soludecadron | ||
|Solupen | |Solupen | ||
− | |||
− | |||
|- | |- | ||
|Sonexa | |Sonexa | ||
Line 600: | Line 502: | ||
|Unidexa | |Unidexa | ||
|Unisone | |Unisone | ||
− | |||
− | |||
|Visualin | |Visualin | ||
|Visumetazone | |Visumetazone | ||
|Voalla | |Voalla | ||
− | |||
|Windex | |Windex | ||
|Wymesone | |Wymesone | ||
+ | |- | ||
|Xasone | |Xasone | ||
|Xine | |Xine | ||
− | |||
|Zalucs | |Zalucs | ||
|Zecaxon | |Zecaxon | ||
|Zenos | |Zenos | ||
+ | |Zydexa | ||
+ | |Baycadron | ||
+ | |ZoDex | ||
|- | |- | ||
− | | | + | |Neofordex |
+ | |LenaDex | ||
|} | |} | ||
Line 621: | Line 524: | ||
<references/> | <references/> | ||
− | [[Category: | + | [[Category:Drugs]] |
− | [[Category: | + | [[Category:Intramuscular medications]] |
+ | [[Category:Intravenous medications]] | ||
+ | [[Category:Oral medications]] | ||
[[Category:Steroids]] | [[Category:Steroids]] | ||
− | [[Category: | + | [[Category:Anaplastic large cell lymphoma medications]] |
− | [[Category: | + | [[Category:B-cell acute lymphoblastic leukemia medications]] |
+ | [[Category:Burkitt lymphoma medications]] | ||
+ | [[Category:CNS lymphoma medications]] | ||
+ | [[Category:Diffuse large B-cell lymphoma medications]] | ||
+ | [[Category:Extranodal NK- and T-cell lymphoma, nasal type medications]] | ||
[[Category:Follicular lymphoma medications]] | [[Category:Follicular lymphoma medications]] | ||
+ | [[Category:Hemophagocytic lymphohistiocytosis medications]] | ||
[[Category:HIV-associated lymphoma medications]] | [[Category:HIV-associated lymphoma medications]] | ||
− | [[Category:Immune | + | [[Category:Classical Hodgkin lymphoma medications]] |
+ | [[Category:Immune thrombocytopenia medications]] | ||
[[Category:Light-chain (AL) amyloidosis medications]] | [[Category:Light-chain (AL) amyloidosis medications]] | ||
[[Category:Mantle cell lymphoma medications]] | [[Category:Mantle cell lymphoma medications]] | ||
[[Category:Multiple myeloma medications]] | [[Category:Multiple myeloma medications]] | ||
− | [[Category:T-cell lymphoma medications]] | + | [[Category:NK- and T-cell lymphoma medications]] |
+ | [[Category:Peripheral T-cell lymphoma medications]] | ||
+ | [[Category:Plasma cell leukemia medications]] | ||
+ | [[Category:POEMS syndrome medications]] | ||
+ | [[Category:Primary mediastinal B-cell lymphoma medications]] | ||
+ | [[Category:Smoldering multiple myeloma medications]] | ||
+ | [[Category:T-cell acute lymphoblastic leukemia medications]] | ||
+ | [[Category:Transformed lymphoma medications]] | ||
[[Category:Waldenström macroglobulinemia medications]] | [[Category:Waldenström macroglobulinemia medications]] | ||
+ | |||
+ | [[Category:Acute myeloid leukemia medications (historic)]] | ||
+ | [[Category:Prostate cancer medications (historic)]] | ||
+ | |||
+ | [[Category:FDA approved in 1958]] | ||
+ | [[Category:EMA approved in 1952]] | ||
+ | [[Category:WHO Essential Cancer Medicine]] | ||
+ | [[Category:WHO Essential Pain and Palliative Care Medicine]] |
Latest revision as of 00:58, 29 June 2024
General information
Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, antiemetic properties, and anti-inflammatory effects.[1][2]
Route: PO, IV, IM
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information.[1]
Diseases for which it is established (work in progress)
Diseases for which it is used
- Anaplastic large cell lymphoma
- B-cell acute lymphoblastic leukemia
- Burkitt lymphoma
- CNS lymphoma
- Diffuse large B-cell lymphoma
- Extranodal NK- and T-cell lymphoma, nasal type
- Follicular lymphoma
- Hemophagocytic lymphohistiocytosis
- HIV-associated lymphoma
- Classical Hodgkin lymphoma
- Immune thrombocytopenia (ITP)
- Light-chain (AL) amyloidosis
- Mantle cell lymphoma
- Multiple myeloma
- NK- and T-cell lymphoma
- Plasma cell leukemia
- POEMS syndrome
- Primary mediastinal B-cell lymphoma
- Smoldering multiple myeloma
- T-cell acute lymphoblastic leukemia
- Transformed lymphoma
- Waldenström macroglobulinemia
Diseases for which it was used
Patient drug information
- Dexamethasone (Decadron) package insert[1]
- Dexamethasone (Decadron) patient drug information (Chemocare)[3]
- Dexamethasone (Decadron) patient drug information (UpToDate)[4]
History of changes in EMA indication
- 1952-01-01: EURD
History of changes in PMDA indication
- 2010-06-18: New additional indication and a new dosage for the treatment of multiple myeloma.
- 2021-08-25: New indication and a new dosage for the treatment of systemic AL amyloidosis.
Also known as
- Generic names: dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate
- Brand names:
Synonyms | |||||||
---|---|---|---|---|---|---|---|
Aacidexam | Acetato DE Dexametasona | Acetazona | Acolon | Adrecort | Adrekon | Aeroseb-DEX | Afpred Forte-Dexa |
AK-DEX | Aldron | Alfalyl | Alpermell | Amumetazon | Anemul | Aphtasolon | Apidex |
Arcodexan | Auxiloson | Auxison | Auxisone | B Dexzol | Bexine | Beyonas Dexa | Bisuo DS |
Brulin | Bucokon | Bufadexon | Butiol | Canalon | Carbidu | Carulon | Cebedex |
Cellacort | Celudex | Cetadexon | Colircusi Dexametasona | Corodex | Corson | Corsona | Corsone |
Corsum | Corticoidex | Cortidax | Cortidex | Cortidexason | Cortitop | Coyensu | D-Cort |
Dacrosone | Daidoron | Dalalone | Danason | Danasone | Daxilone | Decacin | Decaderm |
Decadolone | Decadran | Decadron | Decadronal | Decadronfosfat | Deca Forte | Decafos | Decalin |
Decalon | Decalona | Decan | Decans | Decaron | Decason | Decasone | Decaspray |
Decazol | Decdak | Decdan | Decicort | Decilone | Decobel | Decolite | Decone |
Decordex | Decorex | Decoron | Decorten | Dectan | Dectancyl | Deexa | Deflaren |
Dekesu | Dekisachosei | Dekort | Deksa | Deksalon | Deksamet | Dellamethasone | Deltafluorene |
Demasone | Demeson | Dermadex | Dermidron | Deronil | Deron S | Derson | Dersone |
Desalark | Desametasone Fosf | Desason | Deson | Detametazon | Detasone | Dethamedin | Dexa |
Dexabene | Dexabeta | Dexacen-4 | Dexacilin | Dexacip | Dexa Clinit | Dexacollyre | Dexacom |
Dexacort | Dexacortal | Dexacortin | Dexacortisone | Dexacortisyl | Dexacotsil | Dexacron | Dexacutis |
Dexaden | Dexaderm | Dexaderme | Dexadermil | Dexadon | Dexadrol | Dexadron | Dexaedo |
Dexafar | Dexafarm | Dexaflam | Dexaflan | Dexagalen | Dexagee | Dexagel | Dexagenta |
Dexaglos | Dexagreen | Dexagrin | Dexahexal | Dexaleniens | Dexalocal | Dexaltin | Dexam |
Dexamag | Dexamark | Dexame | Dexamecortin | Dexamedis | Dexamedix | Dexamedron | Dexameral |
Dexameson | Dexamesone | Dexamet | Dexametason | Dexametasona | Dexametax | Dexametazon | Dexametazona |
Dexameth | Dexamethason | Dexamethasonum | Dexamethazon | Dexamethazone | Dexametin | Dexametisona | Dexametonal |
Dexametrat | Dexamex | Dexamil | Dexamine | Dexaminor | Dexamo | Dexamonozon N | Dexanel |
Dexan | Dexanil | Dexano | Dexaphos | Dexapolcort | Dexapro | Dexaril | Dexaroid |
Dexaron | Dexart | Dexasin | Dexasine | Dexasol | Dexasolone | Dexason | Dexasone |
Dexasonlin | Dexatab | Dexaton | Dexatop | Dexatotal | Dexaval | Dexaven | Dexavet |
Dexawal | Dexawieb | Dexazen | Dexazona | Dexazone | Dexicorta | Dexin | Dexinga |
Dexion | Dexmene | Dexmesone | Dexmetha | Dexmethasone | Dexmethsone | Dexona | Dexone |
Dexonium | Dexoptic | Dexpak | Dexsol | Dexstar | Dextason | Dexthasol | Dexton |
Dextrasone | Dicorsone | Dicosheun | Diometa | Dison | DM Solone | Donray | Dorison |
Doronil | Drenex | Drxaline | Elixirmethasone | Epidexone | Epidrone | Erladexone | Ermethasone |
ETA Cortilen | Etason | Euromethasone | Fada Dexametasona | Fadametasona | Faridexon | Fexadron | Fortecortin |
Fosfato Dissodico Dexametasona | Gammacorten | Gemisona | Glymesason | Grathazon | Hexadecadrol | Hexadrol | HI-Methasone |
Hopamethasone | Idizone | Indexon | Inthesa-5 | Irzamethazone | Isodexam | Isopto | Kaarmepakkaus |
Kalmethasone | Kanadex | Kodolo | Kosa | Kovintong | Lanadexon | Licoson | Limethason |
Lipotalon | Lisoderme | Lodex | Lodexa | Lokalison-F | Lormine | Loverine | Lupidexa |
Luxazone | Maradex | Maxidex | Mecoxon | Medesone | Medexasone | Mediamethasone | Medicort |
Medidex | Megacort | Megadex | Mephameson | Mephamesona | Mephamesone | Mephamesone-4 | Meradexon |
Merideca | Mesadoron | Metalexina | Metasolon | Metax | Metaxon | Metcort | Methaderm |
Methasone | Mexasone | Mexaton | Migradexan | Millicorten | Minidex | Mitasone | Molacort |
Mycidex | Neodex | Nexadron | Nodevex | Nufadex M | Ocedran | Ocudex | Oftadek |
Oftadex | Omedexon | Onadron | Ophth-DEX | Ophthasona | Opticort | Orazone | Ordex |
Orgadrone | Penatone | Penodex | Phenodex | Pidexon | Plavex | Plidexa | Prodexon |
Pyderma | Pyradexon | Rally-A | Randexa | Redexon | Rednisone | Reusan | Rocolone |
Ronic | Roximeth | Rupedex | Santeson | Sawasone | Scandexon | Selftison | Shirodex |
Shuayan | Smile | Solcort | Soldesam | Soldesanil | Soldex | Soludecadron | Solupen |
Sonexa | SP Cordexa | Spersadex | Spondy-Dexa | Stedex | Steralol | Sterasone | Steron |
Superprednol | Supertendin-Depot N | Suprason | Surodex | Sydencort | Syndexa | Tavesona | Teanlang |
Teikason Nidek | Tekuron | Thilodex | Thilodexine | Totocortin | Tuttozem N | Ucalon | Udicort |
Unidex | Unidexa | Unisone | Visualin | Visumetazone | Voalla | Windex | Wymesone |
Xasone | Xine | Zalucs | Zecaxon | Zenos | Zydexa | Baycadron | ZoDex |
Neofordex | LenaDex |
References
Categories:
- Drugs
- Intramuscular medications
- Intravenous medications
- Oral medications
- Steroids
- Anaplastic large cell lymphoma medications
- B-cell acute lymphoblastic leukemia medications
- Burkitt lymphoma medications
- CNS lymphoma medications
- Diffuse large B-cell lymphoma medications
- Extranodal NK- and T-cell lymphoma, nasal type medications
- Follicular lymphoma medications
- Hemophagocytic lymphohistiocytosis medications
- HIV-associated lymphoma medications
- Classical Hodgkin lymphoma medications
- Immune thrombocytopenia medications
- Light-chain (AL) amyloidosis medications
- Mantle cell lymphoma medications
- Multiple myeloma medications
- NK- and T-cell lymphoma medications
- Peripheral T-cell lymphoma medications
- Plasma cell leukemia medications
- POEMS syndrome medications
- Primary mediastinal B-cell lymphoma medications
- Smoldering multiple myeloma medications
- T-cell acute lymphoblastic leukemia medications
- Transformed lymphoma medications
- Waldenström macroglobulinemia medications
- Acute myeloid leukemia medications (historic)
- Prostate cancer medications (historic)
- FDA approved in 1958
- EMA approved in 1952
- WHO Essential Cancer Medicine
- WHO Essential Pain and Palliative Care Medicine