POEMS syndrome

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Andrew J. Cowan, MD
University of Washington
Seattle, WA

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POEMS: Peripheral neuropathy, Organomegaly, Endocrinopathy, Monoclonal plasma cell disorder, and Skin changes

1 regimens on this page
1 variants on this page


Guidelines

EMN

All lines of therapy

Rd

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Rd: Revlimid (Lenalidomide) & low-dose dexamethasone

Regimen

Study Evidence
Nozza et al. 2017 Phase II, <20 pts

Chemotherapy

Supportive medications

28-day cycle for at least 6 cycles

References

  1. Nozza A, Terenghi F, Gallia F, Adami F, Briani C, Merlini G, Giordano L, Santoro A, Nobile-Orazio E. Lenalidomide and dexamethasone in patients with POEMS syndrome: results of a prospective, open-label trial. Br J Haematol. 2017 Dec;179(5):748-755. Epub 2017 Oct 19. link to original article contains verified protocol PubMed