Difference between revisions of "Dexamethasone (Decadron)"
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Warner-admin (talk | contribs) m (Text replacement - "manufacturer. Instead" to "manufacturer. Instead") |
Warner-admin (talk | contribs) m (Text replacement - "please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [https://online.lexi.com/lco/action/login UpToDate Lexidrug], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information" to "please refer to your preferred pharmacopeias or the prescribing information") |
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==General information== | ==General information== | ||
− | Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, [[Antiemesis|antiemetic properties]], and anti-inflammatory effects.<ref name="insert">[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]</ref><ref>[[ | + | Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, [[Antiemesis|antiemetic properties]], and anti-inflammatory effects.<ref name="insert">[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]</ref><ref>[[:File:Dexamethasone.pdf | Dexamethasone (Decadron) package insert (locally hosted backup)]]</ref> |
<br>Route: PO, IV, IM | <br>Route: PO, IV, IM | ||
<br>Extravasation: no information | <br>Extravasation: no information | ||
Line 6: | Line 6: | ||
*[[Steroid conversions]] | *[[Steroid conversions]] | ||
− | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias | + | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information.<ref name="insert"></ref> |
+ | |||
+ | ==Diseases for which it is established ''(work in progress)''== | ||
+ | *[[Peripheral T-cell lymphoma]] | ||
==Diseases for which it is used== | ==Diseases for which it is used== | ||
+ | <div style="column-count:3;-moz-column-count:3;-webkit-column-count:3"> | ||
*[[Anaplastic large cell lymphoma]] | *[[Anaplastic large cell lymphoma]] | ||
− | |||
*[[B-cell acute lymphoblastic leukemia]] | *[[B-cell acute lymphoblastic leukemia]] | ||
*[[Burkitt lymphoma]] | *[[Burkitt lymphoma]] | ||
*[[CNS lymphoma]] | *[[CNS lymphoma]] | ||
*[[Diffuse large B-cell lymphoma]] | *[[Diffuse large B-cell lymphoma]] | ||
− | *[[Extranodal NK | + | *[[Extranodal NK- and T-cell lymphoma, nasal type]] |
*[[Follicular lymphoma]] | *[[Follicular lymphoma]] | ||
*[[Hemophagocytic lymphohistiocytosis]] | *[[Hemophagocytic lymphohistiocytosis]] | ||
*[[HIV-associated lymphoma]] | *[[HIV-associated lymphoma]] | ||
− | *[[Hodgkin lymphoma]] | + | *[[Classical Hodgkin lymphoma]] |
+ | *[[Immune thrombocytopenia (ITP)]] | ||
*[[Light-chain (AL) amyloidosis]] | *[[Light-chain (AL) amyloidosis]] | ||
*[[Mantle cell lymphoma]] | *[[Mantle cell lymphoma]] | ||
− | |||
*[[Multiple myeloma]] | *[[Multiple myeloma]] | ||
− | *[[NK | + | *[[NK- and T-cell lymphoma]] |
− | |||
*[[Plasma cell leukemia]] | *[[Plasma cell leukemia]] | ||
+ | *[[POEMS syndrome]] | ||
*[[Primary mediastinal B-cell lymphoma]] | *[[Primary mediastinal B-cell lymphoma]] | ||
+ | *[[Smoldering multiple myeloma]] | ||
*[[T-cell acute lymphoblastic leukemia]] | *[[T-cell acute lymphoblastic leukemia]] | ||
*[[Transformed lymphoma]] | *[[Transformed lymphoma]] | ||
*[[Waldenström macroglobulinemia]] | *[[Waldenström macroglobulinemia]] | ||
+ | </div> | ||
+ | |||
+ | ==Diseases for which it was used== | ||
+ | *[[Acute myeloid leukemia - historical|Acute myeloid leukemia]] | ||
+ | *[[Prostate cancer - historical|Prostate cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
− | *[http://chemocare.com/ | + | *[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]<ref name="insert"></ref> |
+ | *[https://chemocare.com/druginfo/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]<ref>[https://chemocare.com/druginfo/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]</ref> | ||
+ | |||
+ | ==History of changes in EMA indication== | ||
+ | *1952-01-01: EURD | ||
+ | ==History of changes in PMDA indication== | ||
+ | *2010-06-18: New additional indication and a new dosage for the treatment of [[multiple myeloma]]. | ||
+ | *2021-08-25: New indication and a new dosage for the treatment of [[Light-chain (AL) amyloidosis|systemic AL amyloidosis]]. | ||
==Also known as== | ==Also known as== | ||
− | + | *'''Generic names:''' dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate | |
− | + | *'''Brand names:''' | |
− | + | {| class="wikitable" style="text-align:center;" | |
− | |||
− | |||
− | {| | ||
!colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | !colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms''' | ||
|- | |- | ||
Line 63: | Line 76: | ||
|Apidex | |Apidex | ||
|- | |- | ||
− | |||
|Arcodexan | |Arcodexan | ||
|Auxiloson | |Auxiloson | ||
Line 71: | Line 83: | ||
|Bexine | |Bexine | ||
|Beyonas Dexa | |Beyonas Dexa | ||
+ | |Bisuo DS | ||
|- | |- | ||
− | |||
|Brulin | |Brulin | ||
|Bucokon | |Bucokon | ||
Line 80: | Line 92: | ||
|Carbidu | |Carbidu | ||
|Carulon | |Carulon | ||
+ | |Cebedex | ||
|- | |- | ||
− | |||
|Cellacort | |Cellacort | ||
|Celudex | |Celudex | ||
Line 89: | Line 101: | ||
|Corson | |Corson | ||
|Corsona | |Corsona | ||
+ | |Corsone | ||
|- | |- | ||
− | |||
|Corsum | |Corsum | ||
|Corticoidex | |Corticoidex | ||
Line 98: | Line 110: | ||
|Cortitop | |Cortitop | ||
|Coyensu | |Coyensu | ||
+ | |D-Cort | ||
|- | |- | ||
− | |||
|Dacrosone | |Dacrosone | ||
|Daidoron | |Daidoron | ||
|Dalalone | |Dalalone | ||
− | |||
− | |||
|Danason | |Danason | ||
|Danasone | |Danasone | ||
− | |||
|Daxilone | |Daxilone | ||
|Decacin | |Decacin | ||
|Decaderm | |Decaderm | ||
+ | |- | ||
|Decadolone | |Decadolone | ||
|Decadran | |Decadran | ||
− | |||
|Decadron | |Decadron | ||
− | |||
− | |||
− | |||
− | |||
|Decadronal | |Decadronal | ||
|Decadronfosfat | |Decadronfosfat | ||
− | |||
− | |||
− | |||
|Deca Forte | |Deca Forte | ||
− | |||
|Decafos | |Decafos | ||
|Decalin | |Decalin | ||
+ | |- | ||
|Decalon | |Decalon | ||
|Decalona | |Decalona | ||
Line 134: | Line 136: | ||
|Decaron | |Decaron | ||
|Decason | |Decason | ||
− | |||
|Decasone | |Decasone | ||
− | |||
|Decaspray | |Decaspray | ||
+ | |- | ||
|Decazol | |Decazol | ||
|Decdak | |Decdak | ||
Line 143: | Line 144: | ||
|Decicort | |Decicort | ||
|Decilone | |Decilone | ||
− | |||
|Decobel | |Decobel | ||
|Decolite | |Decolite | ||
|Decone | |Decone | ||
+ | |- | ||
|Decordex | |Decordex | ||
|Decorex | |Decorex | ||
Line 152: | Line 153: | ||
|Decorten | |Decorten | ||
|Dectan | |Dectan | ||
− | |||
− | |||
− | |||
|Dectancyl | |Dectancyl | ||
|Deexa | |Deexa | ||
|Deflaren | |Deflaren | ||
+ | |- | ||
|Dekesu | |Dekesu | ||
|Dekisachosei | |Dekisachosei | ||
|Dekort | |Dekort | ||
− | |||
|Deksa | |Deksa | ||
|Deksalon | |Deksalon | ||
Line 167: | Line 165: | ||
|Dellamethasone | |Dellamethasone | ||
|Deltafluorene | |Deltafluorene | ||
+ | |- | ||
|Demasone | |Demasone | ||
|Demeson | |Demeson | ||
|Dermadex | |Dermadex | ||
− | |||
|Dermidron | |Dermidron | ||
|Deronil | |Deronil | ||
Line 176: | Line 174: | ||
|Derson | |Derson | ||
|Dersone | |Dersone | ||
+ | |- | ||
|Desalark | |Desalark | ||
|Desametasone Fosf | |Desametasone Fosf | ||
|Desason | |Desason | ||
− | |||
|Deson | |Deson | ||
|Detametazon | |Detametazon | ||
Line 185: | Line 183: | ||
|Dethamedin | |Dethamedin | ||
|Dexa | |Dexa | ||
− | |||
− | |||
− | |||
|- | |- | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
|Dexabene | |Dexabene | ||
|Dexabeta | |Dexabeta | ||
− | |||
|Dexacen-4 | |Dexacen-4 | ||
− | |||
|Dexacilin | |Dexacilin | ||
|Dexacip | |Dexacip | ||
Line 205: | Line 192: | ||
|Dexacollyre | |Dexacollyre | ||
|Dexacom | |Dexacom | ||
+ | |- | ||
|Dexacort | |Dexacort | ||
− | |||
|Dexacortal | |Dexacortal | ||
|Dexacortin | |Dexacortin | ||
Line 214: | Line 201: | ||
|Dexacron | |Dexacron | ||
|Dexacutis | |Dexacutis | ||
+ | |- | ||
|Dexaden | |Dexaden | ||
− | |||
|Dexaderm | |Dexaderm | ||
|Dexaderme | |Dexaderme | ||
|Dexadermil | |Dexadermil | ||
|Dexadon | |Dexadon | ||
− | |||
|Dexadrol | |Dexadrol | ||
|Dexadron | |Dexadron | ||
Line 227: | Line 213: | ||
|Dexafar | |Dexafar | ||
|Dexafarm | |Dexafarm | ||
− | |||
|Dexaflam | |Dexaflam | ||
− | |||
|Dexaflan | |Dexaflan | ||
|Dexagalen | |Dexagalen | ||
|Dexagee | |Dexagee | ||
− | |||
|Dexagel | |Dexagel | ||
|Dexagenta | |Dexagenta | ||
+ | |- | ||
|Dexaglos | |Dexaglos | ||
|Dexagreen | |Dexagreen | ||
Line 242: | Line 226: | ||
|Dexaleniens | |Dexaleniens | ||
|Dexalocal | |Dexalocal | ||
− | |||
− | |||
|Dexaltin | |Dexaltin | ||
|Dexam | |Dexam | ||
+ | |- | ||
|Dexamag | |Dexamag | ||
|Dexamark | |Dexamark | ||
Line 251: | Line 234: | ||
|Dexamecortin | |Dexamecortin | ||
|Dexamedis | |Dexamedis | ||
− | |||
− | |||
|Dexamedix | |Dexamedix | ||
|Dexamedron | |Dexamedron | ||
|Dexameral | |Dexameral | ||
+ | |- | ||
|Dexameson | |Dexameson | ||
|Dexamesone | |Dexamesone | ||
|Dexamet | |Dexamet | ||
|Dexametason | |Dexametason | ||
− | |||
|Dexametasona | |Dexametasona | ||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
|Dexametax | |Dexametax | ||
|Dexametazon | |Dexametazon | ||
|Dexametazona | |Dexametazona | ||
+ | |- | ||
|Dexameth | |Dexameth | ||
|Dexamethason | |Dexamethason | ||
− | |||
− | |||
− | |||
− | |||
− | |||
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− | |||
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− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
− | |||
|Dexamethasonum | |Dexamethasonum | ||
|Dexamethazon | |Dexamethazon | ||
Line 340: | Line 255: | ||
|Dexametisona | |Dexametisona | ||
|Dexametonal | |Dexametonal | ||
+ | |- | ||
|Dexametrat | |Dexametrat | ||
− | |||
|Dexamex | |Dexamex | ||
|Dexamil | |Dexamil | ||
Line 349: | Line 264: | ||
|Dexamonozon N | |Dexamonozon N | ||
|Dexanel | |Dexanel | ||
− | |||
|- | |- | ||
+ | |Dexan | ||
|Dexanil | |Dexanil | ||
− | |||
|Dexano | |Dexano | ||
− | |||
− | |||
|Dexaphos | |Dexaphos | ||
|Dexapolcort | |Dexapolcort | ||
|Dexapro | |Dexapro | ||
− | |||
− | |||
− | |||
|Dexaril | |Dexaril | ||
|Dexaroid | |Dexaroid | ||
+ | |- | ||
|Dexaron | |Dexaron | ||
|Dexart | |Dexart | ||
− | |||
|Dexasin | |Dexasin | ||
− | |||
|Dexasine | |Dexasine | ||
|Dexasol | |Dexasol | ||
Line 374: | Line 282: | ||
|Dexason | |Dexason | ||
|Dexasone | |Dexasone | ||
+ | |- | ||
|Dexasonlin | |Dexasonlin | ||
|Dexatab | |Dexatab | ||
|Dexaton | |Dexaton | ||
− | |||
|Dexatop | |Dexatop | ||
|Dexatotal | |Dexatotal | ||
|Dexaval | |Dexaval | ||
− | |||
|Dexaven | |Dexaven | ||
|Dexavet | |Dexavet | ||
− | | | + | |- |
|Dexawal | |Dexawal | ||
− | |||
|Dexawieb | |Dexawieb | ||
|Dexazen | |Dexazen | ||
Line 394: | Line 300: | ||
|Dexin | |Dexin | ||
|Dexinga | |Dexinga | ||
+ | |- | ||
|Dexion | |Dexion | ||
− | |||
|Dexmene | |Dexmene | ||
|Dexmesone | |Dexmesone | ||
Line 401: | Line 307: | ||
|Dexmethasone | |Dexmethasone | ||
|Dexmethsone | |Dexmethsone | ||
− | |||
|Dexona | |Dexona | ||
|Dexone | |Dexone | ||
Line 410: | Line 315: | ||
|Dexsol | |Dexsol | ||
|Dexstar | |Dexstar | ||
− | |||
|Dextason | |Dextason | ||
− | |||
− | |||
|Dexthasol | |Dexthasol | ||
− | |||
|Dexton | |Dexton | ||
+ | |- | ||
|Dextrasone | |Dextrasone | ||
|Dicorsone | |Dicorsone | ||
Line 422: | Line 324: | ||
|Diometa | |Diometa | ||
|Dison | |Dison | ||
− | + | |DM Solone | |
− | |DM Solone | ||
− | |||
− | |||
|Donray | |Donray | ||
|Dorison | |Dorison | ||
+ | |- | ||
|Doronil | |Doronil | ||
|Drenex | |Drenex | ||
|Drxaline | |Drxaline | ||
− | |||
|Elixirmethasone | |Elixirmethasone | ||
|Epidexone | |Epidexone | ||
Line 437: | Line 336: | ||
|Erladexone | |Erladexone | ||
|Ermethasone | |Ermethasone | ||
+ | |- | ||
|ETA Cortilen | |ETA Cortilen | ||
|Etason | |Etason | ||
|Euromethasone | |Euromethasone | ||
− | |||
|Fada Dexametasona | |Fada Dexametasona | ||
|Fadametasona | |Fadametasona | ||
Line 446: | Line 345: | ||
|Fexadron | |Fexadron | ||
|Fortecortin | |Fortecortin | ||
− | | | + | |- |
|Fosfato Dissodico Dexametasona | |Fosfato Dissodico Dexametasona | ||
|Gammacorten | |Gammacorten | ||
− | |||
|Gemisona | |Gemisona | ||
|Glymesason | |Glymesason | ||
Line 455: | Line 353: | ||
|Hexadecadrol | |Hexadecadrol | ||
|Hexadrol | |Hexadrol | ||
− | |||
|HI-Methasone | |HI-Methasone | ||
+ | |- | ||
|Hopamethasone | |Hopamethasone | ||
− | |||
|Idizone | |Idizone | ||
|Indexon | |Indexon | ||
Line 464: | Line 361: | ||
|Irzamethazone | |Irzamethazone | ||
|Isodexam | |Isodexam | ||
− | |Isopto | + | |Isopto |
− | | | + | |Kaarmepakkaus |
− | |||
|- | |- | ||
− | |||
|Kalmethasone | |Kalmethasone | ||
|Kanadex | |Kanadex | ||
Line 476: | Line 371: | ||
|Lanadexon | |Lanadexon | ||
|Licoson | |Licoson | ||
+ | |Limethason | ||
|- | |- | ||
− | |||
− | |||
|Lipotalon | |Lipotalon | ||
|Lisoderme | |Lisoderme | ||
Line 485: | Line 379: | ||
|Lokalison-F | |Lokalison-F | ||
|Lormine | |Lormine | ||
− | |||
|Loverine | |Loverine | ||
|Lupidexa | |Lupidexa | ||
+ | |- | ||
|Luxazone | |Luxazone | ||
|Maradex | |Maradex | ||
− | |Maxidex | + | |Maxidex |
|Mecoxon | |Mecoxon | ||
|Medesone | |Medesone | ||
|Medexasone | |Medexasone | ||
− | |||
|Mediamethasone | |Mediamethasone | ||
|Medicort | |Medicort | ||
+ | |- | ||
|Medidex | |Medidex | ||
|Megacort | |Megacort | ||
Line 503: | Line 397: | ||
|Mephamesona | |Mephamesona | ||
|Mephamesone | |Mephamesone | ||
− | |||
|Mephamesone-4 | |Mephamesone-4 | ||
|Meradexon | |Meradexon | ||
+ | |- | ||
|Merideca | |Merideca | ||
− | |Mesadoron | + | |Mesadoron |
− | |||
|Metalexina | |Metalexina | ||
|Metasolon | |Metasolon | ||
|Metax | |Metax | ||
− | |||
|Metaxon | |Metaxon | ||
|Metcort | |Metcort | ||
|Methaderm | |Methaderm | ||
+ | |- | ||
|Methasone | |Methasone | ||
|Mexasone | |Mexasone | ||
|Mexaton | |Mexaton | ||
− | |||
|Migradexan | |Migradexan | ||
− | |||
|Millicorten | |Millicorten | ||
|Minidex | |Minidex | ||
− | |||
|Mitasone | |Mitasone | ||
|Molacort | |Molacort | ||
− | | | + | |- |
|Mycidex | |Mycidex | ||
|Neodex | |Neodex | ||
− | |||
|Nexadron | |Nexadron | ||
− | |||
|Nodevex | |Nodevex | ||
|Nufadex M | |Nufadex M | ||
Line 538: | Line 426: | ||
|Ocudex | |Ocudex | ||
|Oftadek | |Oftadek | ||
+ | |- | ||
|Oftadex | |Oftadex | ||
− | |||
− | |||
− | |||
|Omedexon | |Omedexon | ||
|Onadron | |Onadron | ||
Line 548: | Line 434: | ||
|Opticort | |Opticort | ||
|Orazone | |Orazone | ||
+ | |Ordex | ||
|- | |- | ||
− | |||
|Orgadrone | |Orgadrone | ||
− | |||
|Penatone | |Penatone | ||
|Penodex | |Penodex | ||
Line 557: | Line 442: | ||
|Pidexon | |Pidexon | ||
|Plavex | |Plavex | ||
− | |||
|Plidexa | |Plidexa | ||
− | |||
|Prodexon | |Prodexon | ||
+ | |- | ||
|Pyderma | |Pyderma | ||
|Pyradexon | |Pyradexon | ||
Line 566: | Line 450: | ||
|Randexa | |Randexa | ||
|Redexon | |Redexon | ||
− | |||
|Rednisone | |Rednisone | ||
|Reusan | |Reusan | ||
|Rocolone | |Rocolone | ||
+ | |- | ||
|Ronic | |Ronic | ||
|Roximeth | |Roximeth | ||
|Rupedex | |Rupedex | ||
− | |||
− | |||
− | |||
|Santeson | |Santeson | ||
|Sawasone | |Sawasone | ||
Line 581: | Line 462: | ||
|Selftison | |Selftison | ||
|Shirodex | |Shirodex | ||
+ | |- | ||
|Shuayan | |Shuayan | ||
|Smile | |Smile | ||
|Solcort | |Solcort | ||
− | |||
|Soldesam | |Soldesam | ||
− | |||
|Soldesanil | |Soldesanil | ||
|Soldex | |Soldex | ||
|Soludecadron | |Soludecadron | ||
|Solupen | |Solupen | ||
− | |||
− | |||
|- | |- | ||
|Sonexa | |Sonexa | ||
Line 624: | Line 502: | ||
|Unidexa | |Unidexa | ||
|Unisone | |Unisone | ||
− | |||
− | |||
|Visualin | |Visualin | ||
|Visumetazone | |Visumetazone | ||
|Voalla | |Voalla | ||
− | |||
|Windex | |Windex | ||
|Wymesone | |Wymesone | ||
+ | |- | ||
|Xasone | |Xasone | ||
|Xine | |Xine | ||
− | |||
|Zalucs | |Zalucs | ||
|Zecaxon | |Zecaxon | ||
|Zenos | |Zenos | ||
+ | |Zydexa | ||
+ | |Baycadron | ||
+ | |ZoDex | ||
|- | |- | ||
− | | | + | |Neofordex |
+ | |LenaDex | ||
|} | |} | ||
Line 645: | Line 524: | ||
<references/> | <references/> | ||
− | [[Category: | + | [[Category:Drugs]] |
+ | [[Category:Intramuscular medications]] | ||
+ | [[Category:Intravenous medications]] | ||
+ | [[Category:Oral medications]] | ||
[[Category:Steroids]] | [[Category:Steroids]] | ||
Line 651: | Line 533: | ||
[[Category:B-cell acute lymphoblastic leukemia medications]] | [[Category:B-cell acute lymphoblastic leukemia medications]] | ||
[[Category:Burkitt lymphoma medications]] | [[Category:Burkitt lymphoma medications]] | ||
− | [[Category: | + | [[Category:CNS lymphoma medications]] |
[[Category:Diffuse large B-cell lymphoma medications]] | [[Category:Diffuse large B-cell lymphoma medications]] | ||
− | [[Category:Extranodal NK | + | [[Category:Extranodal NK- and T-cell lymphoma, nasal type medications]] |
[[Category:Follicular lymphoma medications]] | [[Category:Follicular lymphoma medications]] | ||
[[Category:Hemophagocytic lymphohistiocytosis medications]] | [[Category:Hemophagocytic lymphohistiocytosis medications]] | ||
[[Category:HIV-associated lymphoma medications]] | [[Category:HIV-associated lymphoma medications]] | ||
− | [[Category:Hodgkin lymphoma medications]] | + | [[Category:Classical Hodgkin lymphoma medications]] |
− | [[Category:Immune | + | [[Category:Immune thrombocytopenia medications]] |
[[Category:Light-chain (AL) amyloidosis medications]] | [[Category:Light-chain (AL) amyloidosis medications]] | ||
[[Category:Mantle cell lymphoma medications]] | [[Category:Mantle cell lymphoma medications]] | ||
[[Category:Multiple myeloma medications]] | [[Category:Multiple myeloma medications]] | ||
− | [[Category:NK | + | [[Category:NK- and T-cell lymphoma medications]] |
[[Category:Peripheral T-cell lymphoma medications]] | [[Category:Peripheral T-cell lymphoma medications]] | ||
[[Category:Plasma cell leukemia medications]] | [[Category:Plasma cell leukemia medications]] | ||
+ | [[Category:POEMS syndrome medications]] | ||
[[Category:Primary mediastinal B-cell lymphoma medications]] | [[Category:Primary mediastinal B-cell lymphoma medications]] | ||
+ | [[Category:Smoldering multiple myeloma medications]] | ||
[[Category:T-cell acute lymphoblastic leukemia medications]] | [[Category:T-cell acute lymphoblastic leukemia medications]] | ||
[[Category:Transformed lymphoma medications]] | [[Category:Transformed lymphoma medications]] | ||
[[Category:Waldenström macroglobulinemia medications]] | [[Category:Waldenström macroglobulinemia medications]] | ||
− | [[Category: | + | [[Category:Acute myeloid leukemia medications (historic)]] |
+ | [[Category:Prostate cancer medications (historic)]] | ||
+ | |||
+ | [[Category:FDA approved in 1958]] | ||
+ | [[Category:EMA approved in 1952]] | ||
[[Category:WHO Essential Cancer Medicine]] | [[Category:WHO Essential Cancer Medicine]] | ||
[[Category:WHO Essential Pain and Palliative Care Medicine]] | [[Category:WHO Essential Pain and Palliative Care Medicine]] |
Latest revision as of 00:58, 29 June 2024
General information
Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, antiemetic properties, and anti-inflammatory effects.[1][2]
Route: PO, IV, IM
Extravasation: no information
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias or the prescribing information.[1]
Diseases for which it is established (work in progress)
Diseases for which it is used
- Anaplastic large cell lymphoma
- B-cell acute lymphoblastic leukemia
- Burkitt lymphoma
- CNS lymphoma
- Diffuse large B-cell lymphoma
- Extranodal NK- and T-cell lymphoma, nasal type
- Follicular lymphoma
- Hemophagocytic lymphohistiocytosis
- HIV-associated lymphoma
- Classical Hodgkin lymphoma
- Immune thrombocytopenia (ITP)
- Light-chain (AL) amyloidosis
- Mantle cell lymphoma
- Multiple myeloma
- NK- and T-cell lymphoma
- Plasma cell leukemia
- POEMS syndrome
- Primary mediastinal B-cell lymphoma
- Smoldering multiple myeloma
- T-cell acute lymphoblastic leukemia
- Transformed lymphoma
- Waldenström macroglobulinemia
Diseases for which it was used
Patient drug information
- Dexamethasone (Decadron) package insert[1]
- Dexamethasone (Decadron) patient drug information (Chemocare)[3]
- Dexamethasone (Decadron) patient drug information (UpToDate)[4]
History of changes in EMA indication
- 1952-01-01: EURD
History of changes in PMDA indication
- 2010-06-18: New additional indication and a new dosage for the treatment of multiple myeloma.
- 2021-08-25: New indication and a new dosage for the treatment of systemic AL amyloidosis.
Also known as
- Generic names: dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate
- Brand names:
Synonyms | |||||||
---|---|---|---|---|---|---|---|
Aacidexam | Acetato DE Dexametasona | Acetazona | Acolon | Adrecort | Adrekon | Aeroseb-DEX | Afpred Forte-Dexa |
AK-DEX | Aldron | Alfalyl | Alpermell | Amumetazon | Anemul | Aphtasolon | Apidex |
Arcodexan | Auxiloson | Auxison | Auxisone | B Dexzol | Bexine | Beyonas Dexa | Bisuo DS |
Brulin | Bucokon | Bufadexon | Butiol | Canalon | Carbidu | Carulon | Cebedex |
Cellacort | Celudex | Cetadexon | Colircusi Dexametasona | Corodex | Corson | Corsona | Corsone |
Corsum | Corticoidex | Cortidax | Cortidex | Cortidexason | Cortitop | Coyensu | D-Cort |
Dacrosone | Daidoron | Dalalone | Danason | Danasone | Daxilone | Decacin | Decaderm |
Decadolone | Decadran | Decadron | Decadronal | Decadronfosfat | Deca Forte | Decafos | Decalin |
Decalon | Decalona | Decan | Decans | Decaron | Decason | Decasone | Decaspray |
Decazol | Decdak | Decdan | Decicort | Decilone | Decobel | Decolite | Decone |
Decordex | Decorex | Decoron | Decorten | Dectan | Dectancyl | Deexa | Deflaren |
Dekesu | Dekisachosei | Dekort | Deksa | Deksalon | Deksamet | Dellamethasone | Deltafluorene |
Demasone | Demeson | Dermadex | Dermidron | Deronil | Deron S | Derson | Dersone |
Desalark | Desametasone Fosf | Desason | Deson | Detametazon | Detasone | Dethamedin | Dexa |
Dexabene | Dexabeta | Dexacen-4 | Dexacilin | Dexacip | Dexa Clinit | Dexacollyre | Dexacom |
Dexacort | Dexacortal | Dexacortin | Dexacortisone | Dexacortisyl | Dexacotsil | Dexacron | Dexacutis |
Dexaden | Dexaderm | Dexaderme | Dexadermil | Dexadon | Dexadrol | Dexadron | Dexaedo |
Dexafar | Dexafarm | Dexaflam | Dexaflan | Dexagalen | Dexagee | Dexagel | Dexagenta |
Dexaglos | Dexagreen | Dexagrin | Dexahexal | Dexaleniens | Dexalocal | Dexaltin | Dexam |
Dexamag | Dexamark | Dexame | Dexamecortin | Dexamedis | Dexamedix | Dexamedron | Dexameral |
Dexameson | Dexamesone | Dexamet | Dexametason | Dexametasona | Dexametax | Dexametazon | Dexametazona |
Dexameth | Dexamethason | Dexamethasonum | Dexamethazon | Dexamethazone | Dexametin | Dexametisona | Dexametonal |
Dexametrat | Dexamex | Dexamil | Dexamine | Dexaminor | Dexamo | Dexamonozon N | Dexanel |
Dexan | Dexanil | Dexano | Dexaphos | Dexapolcort | Dexapro | Dexaril | Dexaroid |
Dexaron | Dexart | Dexasin | Dexasine | Dexasol | Dexasolone | Dexason | Dexasone |
Dexasonlin | Dexatab | Dexaton | Dexatop | Dexatotal | Dexaval | Dexaven | Dexavet |
Dexawal | Dexawieb | Dexazen | Dexazona | Dexazone | Dexicorta | Dexin | Dexinga |
Dexion | Dexmene | Dexmesone | Dexmetha | Dexmethasone | Dexmethsone | Dexona | Dexone |
Dexonium | Dexoptic | Dexpak | Dexsol | Dexstar | Dextason | Dexthasol | Dexton |
Dextrasone | Dicorsone | Dicosheun | Diometa | Dison | DM Solone | Donray | Dorison |
Doronil | Drenex | Drxaline | Elixirmethasone | Epidexone | Epidrone | Erladexone | Ermethasone |
ETA Cortilen | Etason | Euromethasone | Fada Dexametasona | Fadametasona | Faridexon | Fexadron | Fortecortin |
Fosfato Dissodico Dexametasona | Gammacorten | Gemisona | Glymesason | Grathazon | Hexadecadrol | Hexadrol | HI-Methasone |
Hopamethasone | Idizone | Indexon | Inthesa-5 | Irzamethazone | Isodexam | Isopto | Kaarmepakkaus |
Kalmethasone | Kanadex | Kodolo | Kosa | Kovintong | Lanadexon | Licoson | Limethason |
Lipotalon | Lisoderme | Lodex | Lodexa | Lokalison-F | Lormine | Loverine | Lupidexa |
Luxazone | Maradex | Maxidex | Mecoxon | Medesone | Medexasone | Mediamethasone | Medicort |
Medidex | Megacort | Megadex | Mephameson | Mephamesona | Mephamesone | Mephamesone-4 | Meradexon |
Merideca | Mesadoron | Metalexina | Metasolon | Metax | Metaxon | Metcort | Methaderm |
Methasone | Mexasone | Mexaton | Migradexan | Millicorten | Minidex | Mitasone | Molacort |
Mycidex | Neodex | Nexadron | Nodevex | Nufadex M | Ocedran | Ocudex | Oftadek |
Oftadex | Omedexon | Onadron | Ophth-DEX | Ophthasona | Opticort | Orazone | Ordex |
Orgadrone | Penatone | Penodex | Phenodex | Pidexon | Plavex | Plidexa | Prodexon |
Pyderma | Pyradexon | Rally-A | Randexa | Redexon | Rednisone | Reusan | Rocolone |
Ronic | Roximeth | Rupedex | Santeson | Sawasone | Scandexon | Selftison | Shirodex |
Shuayan | Smile | Solcort | Soldesam | Soldesanil | Soldex | Soludecadron | Solupen |
Sonexa | SP Cordexa | Spersadex | Spondy-Dexa | Stedex | Steralol | Sterasone | Steron |
Superprednol | Supertendin-Depot N | Suprason | Surodex | Sydencort | Syndexa | Tavesona | Teanlang |
Teikason Nidek | Tekuron | Thilodex | Thilodexine | Totocortin | Tuttozem N | Ucalon | Udicort |
Unidex | Unidexa | Unisone | Visualin | Visumetazone | Voalla | Windex | Wymesone |
Xasone | Xine | Zalucs | Zecaxon | Zenos | Zydexa | Baycadron | ZoDex |
Neofordex | LenaDex |
References
Categories:
- Drugs
- Intramuscular medications
- Intravenous medications
- Oral medications
- Steroids
- Anaplastic large cell lymphoma medications
- B-cell acute lymphoblastic leukemia medications
- Burkitt lymphoma medications
- CNS lymphoma medications
- Diffuse large B-cell lymphoma medications
- Extranodal NK- and T-cell lymphoma, nasal type medications
- Follicular lymphoma medications
- Hemophagocytic lymphohistiocytosis medications
- HIV-associated lymphoma medications
- Classical Hodgkin lymphoma medications
- Immune thrombocytopenia medications
- Light-chain (AL) amyloidosis medications
- Mantle cell lymphoma medications
- Multiple myeloma medications
- NK- and T-cell lymphoma medications
- Peripheral T-cell lymphoma medications
- Plasma cell leukemia medications
- POEMS syndrome medications
- Primary mediastinal B-cell lymphoma medications
- Smoldering multiple myeloma medications
- T-cell acute lymphoblastic leukemia medications
- Transformed lymphoma medications
- Waldenström macroglobulinemia medications
- Acute myeloid leukemia medications (historic)
- Prostate cancer medications (historic)
- FDA approved in 1958
- EMA approved in 1952
- WHO Essential Cancer Medicine
- WHO Essential Pain and Palliative Care Medicine