Difference between revisions of "Dexamethasone (Decadron)"

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==General information==
 
==General information==
−
Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, [[Antiemesis|antiemetic properties]], and anti-inflammatory effects.<ref name="insert">[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]</ref><ref>[[Media:Dexamethasone.pdf | Dexamethasone (Decadron) package insert (locally hosted backup)]]</ref>
+
Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, [[Antiemesis|antiemetic properties]], and anti-inflammatory effects.<ref name="insert">[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]</ref><ref>[[:File:Dexamethasone.pdf | Dexamethasone (Decadron) package insert (locally hosted backup)]]</ref>
 
<br>Route: PO, IV, IM
 
<br>Route: PO, IV, IM
 
<br>Extravasation: no information
 
<br>Extravasation: no information
Line 6: Line 6:
 
*[[Steroid conversions]]
 
*[[Steroid conversions]]
  
−
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>  
+
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>  
 +
 
 +
==Diseases for which it is established ''(work in progress)''==
 +
*[[Peripheral T-cell lymphoma]]
  
 
==Diseases for which it is used==
 
==Diseases for which it is used==
−
*[[Acute lymphocytic leukemia]]
+
<div style="column-count:3;-moz-column-count:3;-webkit-column-count:3">
 
*[[Anaplastic large cell lymphoma]]
 
*[[Anaplastic large cell lymphoma]]
−
*[[Autoimmune thrombocytopenic purpura (ITP)]]
+
*[[B-cell acute lymphoblastic leukemia]]
 
*[[Burkitt lymphoma]]
 
*[[Burkitt lymphoma]]
 
*[[CNS lymphoma]]
 
*[[CNS lymphoma]]
 
*[[Diffuse large B-cell lymphoma]]
 
*[[Diffuse large B-cell lymphoma]]
−
*[[Extranodal NK/T-cell lymphoma, nasal type]]
+
*[[Extranodal NK- and T-cell lymphoma, nasal type]]
 
*[[Follicular lymphoma]]
 
*[[Follicular lymphoma]]
 
*[[Hemophagocytic lymphohistiocytosis]]
 
*[[Hemophagocytic lymphohistiocytosis]]
 
*[[HIV-associated lymphoma]]
 
*[[HIV-associated lymphoma]]
−
*[[Hodgkin lymphoma]]
+
*[[Classical Hodgkin lymphoma]]
 +
*[[Immune thrombocytopenia (ITP)]]
 
*[[Light-chain (AL) amyloidosis]]
 
*[[Light-chain (AL) amyloidosis]]
 
*[[Mantle cell lymphoma]]
 
*[[Mantle cell lymphoma]]
−
*[[Mast cell diseases]]
 
 
*[[Multiple myeloma]]
 
*[[Multiple myeloma]]
−
*[[NK/T-cell lymphoma]]
+
*[[NK- and T-cell lymphoma]]
−
*[[Peripheral T-cell lymphoma]]
+
*[[Plasma cell leukemia]]
 +
*[[POEMS syndrome]]
 
*[[Primary mediastinal B-cell lymphoma]]
 
*[[Primary mediastinal B-cell lymphoma]]
 +
*[[Smoldering multiple myeloma]]
 +
*[[T-cell acute lymphoblastic leukemia]]
 
*[[Transformed lymphoma]]
 
*[[Transformed lymphoma]]
 
*[[Waldenström macroglobulinemia]]
 
*[[Waldenström macroglobulinemia]]
 +
</div>
 +
 +
==Diseases for which it was used==
 +
*[[Acute myeloid leukemia - historical|Acute myeloid leukemia]]
 +
*[[Prostate cancer - historical|Prostate cancer]]
  
 
==Patient drug information==
 
==Patient drug information==
−
*[http://chemocare.com/chemotherapy/drug-info/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]</ref>
+
*[http://bidocs.boehringer-ingelheim.com/BIWebAccess/ViewServlet.ser?docBase=renetnt&folderPath=/Prescribing+Information/PIs/Roxane/Dexamethasone/Dexamethasone+Tablets+Solution+and+Intensol.pdf Dexamethasone (Decadron) package insert]<ref name="insert"></ref>
 +
*[https://chemocare.com/druginfo/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]<ref>[https://chemocare.com/druginfo/dexamethasone.aspx Dexamethasone (Decadron) patient drug information (Chemocare)]</ref>
 
*[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]</ref>
 
*[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/dexamethasone-patient-drug-information Dexamethasone (Decadron) patient drug information (UpToDate)]</ref>
 +
 +
==History of changes in EMA indication==
 +
*1952-01-01: EURD
 +
==History of changes in PMDA indication==
 +
*2010-06-18: New additional indication and a new dosage for the treatment of [[multiple myeloma]].
 +
*2021-08-25: New indication and a new dosage for the treatment of [[Light-chain (AL) amyloidosis|systemic AL amyloidosis]].
  
 
==Also known as==
 
==Also known as==
−
Precise Names:
+
*'''Generic names:''' dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate
−
#Dexamethasone Acetate (RXCUI 22690)
+
*'''Brand names:'''
−
#Dexamethasone Phosphate (RXCUI 235486)
+
{| class="wikitable" style="text-align:center;"
−
#Dexamethasone Sodium Phosphate (RXCUI 48933)
 
−
 
 
−
{| border="1" style="text-align:center;"
 
 
!colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms'''
 
!colspan="8" align="center" style="background-color:#0066FF"| '''Synonyms'''
 
|-
 
|-
Line 61: Line 76:
 
|Apidex
 
|Apidex
 
|-
 
|-
−
|APO-Dexamethasone
 
 
|Arcodexan
 
|Arcodexan
 
|Auxiloson
 
|Auxiloson
Line 69: Line 83:
 
|Bexine
 
|Bexine
 
|Beyonas Dexa
 
|Beyonas Dexa
 +
|Bisuo DS
 
|-
 
|-
−
|Bisuo DS
 
 
|Brulin
 
|Brulin
 
|Bucokon
 
|Bucokon
Line 78: Line 92:
 
|Carbidu
 
|Carbidu
 
|Carulon
 
|Carulon
 +
|Cebedex
 
|-
 
|-
−
|Cebedex
 
 
|Cellacort
 
|Cellacort
 
|Celudex
 
|Celudex
Line 87: Line 101:
 
|Corson
 
|Corson
 
|Corsona
 
|Corsona
 +
|Corsone
 
|-
 
|-
−
|Corsone
 
 
|Corsum
 
|Corsum
 
|Corticoidex
 
|Corticoidex
Line 96: Line 110:
 
|Cortitop
 
|Cortitop
 
|Coyensu
 
|Coyensu
 +
|D-Cort
 
|-
 
|-
−
|D-Cort
 
 
|Dacrosone
 
|Dacrosone
 
|Daidoron
 
|Daidoron
 
|Dalalone
 
|Dalalone
−
|Dalalone D.P.
 
−
|Dalalone DP
 
 
|Danason
 
|Danason
 
|Danasone
 
|Danasone
−
|-
 
 
|Daxilone
 
|Daxilone
 
|Decacin
 
|Decacin
 
|Decaderm
 
|Decaderm
 +
|-
 
|Decadolone
 
|Decadolone
 
|Decadran
 
|Decadran
−
|Decadran Oftalmico
 
 
|Decadron
 
|Decadron
−
|Decadron-LA
 
−
|-
 
−
|Decadron A
 
−
|Decadron A.L.
 
 
|Decadronal
 
|Decadronal
 
|Decadronfosfat
 
|Decadronfosfat
−
|Decadron Fosfato
 
−
|Decadron Phosphate
 
−
|Decadron Shock
 
 
|Deca Forte
 
|Deca Forte
−
|-
 
 
|Decafos
 
|Decafos
 
|Decalin
 
|Decalin
 +
|-
 
|Decalon
 
|Decalon
 
|Decalona
 
|Decalona
Line 132: Line 136:
 
|Decaron
 
|Decaron
 
|Decason
 
|Decason
−
|-
 
 
|Decasone
 
|Decasone
−
|Decasone R.P.
 
 
|Decaspray
 
|Decaspray
 +
|-
 
|Decazol
 
|Decazol
 
|Decdak
 
|Decdak
Line 141: Line 144:
 
|Decicort
 
|Decicort
 
|Decilone
 
|Decilone
−
|-
 
 
|Decobel
 
|Decobel
 
|Decolite
 
|Decolite
 
|Decone
 
|Decone
 +
|-
 
|Decordex
 
|Decordex
 
|Decorex
 
|Decorex
Line 150: Line 153:
 
|Decorten
 
|Decorten
 
|Dectan
 
|Dectan
−
|-
 
−
|Dectan Aventis
 
−
|Dectan Chugai
 
 
|Dectancyl
 
|Dectancyl
 
|Deexa
 
|Deexa
 
|Deflaren
 
|Deflaren
 +
|-
 
|Dekesu
 
|Dekesu
 
|Dekisachosei
 
|Dekisachosei
 
|Dekort
 
|Dekort
−
|-
 
 
|Deksa
 
|Deksa
 
|Deksalon
 
|Deksalon
Line 165: Line 165:
 
|Dellamethasone
 
|Dellamethasone
 
|Deltafluorene
 
|Deltafluorene
 +
|-
 
|Demasone
 
|Demasone
 
|Demeson
 
|Demeson
 
|Dermadex
 
|Dermadex
−
|-
 
 
|Dermidron
 
|Dermidron
 
|Deronil
 
|Deronil
Line 174: Line 174:
 
|Derson
 
|Derson
 
|Dersone
 
|Dersone
 +
|-
 
|Desalark
 
|Desalark
 
|Desametasone Fosf
 
|Desametasone Fosf
 
|Desason
 
|Desason
−
|-
 
 
|Deson
 
|Deson
 
|Detametazon
 
|Detametazon
Line 183: Line 183:
 
|Dethamedin
 
|Dethamedin
 
|Dexa
 
|Dexa
−
|Dexa-Brachialin N
 
−
|Dexa-Effekton
 
−
|Dexa-Helvacort
 
 
|-
 
|-
−
|Dexa-O
 
−
|Dexa-P
 
−
|Dexa-WIN
 
−
|Dexa-Y
 
−
|Dexa.mamallet
 
−
|Dexa Allvoran
 
 
|Dexabene
 
|Dexabene
 
|Dexabeta
 
|Dexabeta
−
|-
 
 
|Dexacen-4
 
|Dexacen-4
−
|Dexa Chlorpheniramine
 
 
|Dexacilin
 
|Dexacilin
 
|Dexacip
 
|Dexacip
Line 203: Line 192:
 
|Dexacollyre
 
|Dexacollyre
 
|Dexacom
 
|Dexacom
 +
|-
 
|Dexacort
 
|Dexacort
−
|-
 
 
|Dexacortal
 
|Dexacortal
 
|Dexacortin
 
|Dexacortin
Line 212: Line 201:
 
|Dexacron
 
|Dexacron
 
|Dexacutis
 
|Dexacutis
 +
|-
 
|Dexaden
 
|Dexaden
−
|-
 
 
|Dexaderm
 
|Dexaderm
 
|Dexaderme
 
|Dexaderme
 
|Dexadermil
 
|Dexadermil
 
|Dexadon
 
|Dexadon
−
|Dexadon-21.P
 
 
|Dexadrol
 
|Dexadrol
 
|Dexadron
 
|Dexadron
Line 225: Line 213:
 
|Dexafar
 
|Dexafar
 
|Dexafarm
 
|Dexafarm
−
|Dexa Ferosone
 
 
|Dexaflam
 
|Dexaflam
−
|Dexaflam N
 
 
|Dexaflan
 
|Dexaflan
 
|Dexagalen
 
|Dexagalen
 
|Dexagee
 
|Dexagee
−
|-
 
 
|Dexagel
 
|Dexagel
 
|Dexagenta
 
|Dexagenta
 +
|-
 
|Dexaglos
 
|Dexaglos
 
|Dexagreen
 
|Dexagreen
Line 240: Line 226:
 
|Dexaleniens
 
|Dexaleniens
 
|Dexalocal
 
|Dexalocal
−
|-
 
−
|Dexa Loscon Mono
 
 
|Dexaltin
 
|Dexaltin
 
|Dexam
 
|Dexam
 +
|-
 
|Dexamag
 
|Dexamag
 
|Dexamark
 
|Dexamark
Line 249: Line 234:
 
|Dexamecortin
 
|Dexamecortin
 
|Dexamedis
 
|Dexamedis
−
|-
 
−
|Dexamedis Fort
 
 
|Dexamedix
 
|Dexamedix
 
|Dexamedron
 
|Dexamedron
 
|Dexameral
 
|Dexameral
 +
|-
 
|Dexameson
 
|Dexameson
 
|Dexamesone
 
|Dexamesone
 
|Dexamet
 
|Dexamet
 
|Dexametason
 
|Dexametason
−
|-
 
 
|Dexametasona
 
|Dexametasona
−
|Dexametasona Biocrom
 
−
|Dexametasona Dorf
 
−
|Dexametasona Dunca
 
−
|Dexametasona Fabra
 
−
|Dexametasona GI PI
 
−
|Dexametasona Larjan
 
−
|Dexametasona Richet
 
−
|-
 
 
|Dexametax
 
|Dexametax
 
|Dexametazon
 
|Dexametazon
 
|Dexametazona
 
|Dexametazona
 +
|-
 
|Dexameth
 
|Dexameth
 
|Dexamethason
 
|Dexamethason
−
|Dexamethason-Cophar
 
−
|Dexamethason CF
 
−
|dexamethasone acetate
 
−
|-
 
−
|Dexamethasone Acetate Fuji
 
−
|Dexamethasone Acetate Nichiiko
 
−
|Dexamethasone Amel
 
−
|Dexamethasone Asahi Kasei
 
−
|Dexamethasone Chauvin
 
−
|Dexamethasone Comp
 
−
|Dexamethasone Dipropionate
 
−
|Dexamethasone Fuso
 
−
|-
 
−
|Dexamethasone Intensol
 
−
|Dexamethasone Isei
 
−
|Dexamethasone Isonicotinate
 
−
|Dexamethasone Iwak Seiyaku
 
−
|Dexamethasone Kowa
 
−
|Dexamethasone Merck
 
−
|Dexamethasone Merck Hoei
 
−
|Dexamethasone Mitsubishi
 
−
|-
 
−
|Dexamethasone Nichiiko
 
−
|Dexamethasone Nihon
 
−
|Dexamethasone Nipro
 
−
|Dexamethasone Organon
 
−
|Dexamethasone Paines & Byrne
 
−
|Dexamethasone Palmitate
 
−
|dexamethasone phosphate
 
−
|Dexamethasone S.S. Seiyaku
 
−
|-
 
−
|Dexamethasone Sato
 
−
|Dexamethasone Sawai
 
−
|Dexamethasone S / PH
 
−
|Dexamethasone Showa
 
−
|Dexamethasone Sodium
 
−
|Dexamethasone Sodium Metasulfobenzoate
 
−
|Dexamethasone Sodium Phosphate
 
−
|Dexamethasone Sodium Succinate
 
−
|-
 
−
|Dexamethasone Sodium Sulfate
 
−
|Dexamethasone Taisho
 
−
|Dexamethasone Taiyo
 
−
|Dexamethasone Tebutate
 
−
|Dexamethasone Tobishi
 
−
|Dexamethasone Towa
 
−
|Dexamethasone Valerate
 
−
|Dexamethasone Viatris
 
−
|-
 
−
|Dexamethason Galepharm
 
−
|Dexamethason Helvepharm
 
−
|Dexamethason Jenapharm
 
−
|Dexamethason Krka
 
−
|Dexamethason Lens
 
−
|Dexamethason MP
 
−
|Dexamethason PCH
 
−
|Dexamethason Rotexmedica
 
−
|-
 
−
|Dexamethason Star
 
 
|Dexamethasonum
 
|Dexamethasonum
 
|Dexamethazon
 
|Dexamethazon
Line 338: Line 255:
 
|Dexametisona
 
|Dexametisona
 
|Dexametonal
 
|Dexametonal
 +
|-
 
|Dexametrat
 
|Dexametrat
−
|-
 
 
|Dexamex
 
|Dexamex
 
|Dexamil
 
|Dexamil
Line 347: Line 264:
 
|Dexamonozon N
 
|Dexamonozon N
 
|Dexanel
 
|Dexanel
−
|Dexan Fuji Seiyaku
 
 
|-
 
|-
 +
|Dexan
 
|Dexanil
 
|Dexanil
−
|Dexan Nichiiko
 
 
|Dexano
 
|Dexano
−
|Dexan S.S. Seiyaku
 
−
|Dexa Ophtiole
 
 
|Dexaphos
 
|Dexaphos
 
|Dexapolcort
 
|Dexapolcort
 
|Dexapro
 
|Dexapro
−
|-
 
−
|Dexa Ratiopharm
 
−
|Dexa Rhinaspray Mono
 
 
|Dexaril
 
|Dexaril
 
|Dexaroid
 
|Dexaroid
 +
|-
 
|Dexaron
 
|Dexaron
 
|Dexart
 
|Dexart
−
|Dexa Scheroson
 
 
|Dexasin
 
|Dexasin
−
|-
 
 
|Dexasine
 
|Dexasine
 
|Dexasol
 
|Dexasol
Line 372: Line 282:
 
|Dexason
 
|Dexason
 
|Dexasone
 
|Dexasone
 +
|-
 
|Dexasonlin
 
|Dexasonlin
 
|Dexatab
 
|Dexatab
 
|Dexaton
 
|Dexaton
−
|-
 
 
|Dexatop
 
|Dexatop
 
|Dexatotal
 
|Dexatotal
 
|Dexaval
 
|Dexaval
−
|Dexaval Capila
 
 
|Dexaven
 
|Dexaven
 
|Dexavet
 
|Dexavet
−
|Dexa VON CT
+
|-
 
|Dexawal
 
|Dexawal
−
|-
 
 
|Dexawieb
 
|Dexawieb
 
|Dexazen
 
|Dexazen
Line 392: Line 300:
 
|Dexin
 
|Dexin
 
|Dexinga
 
|Dexinga
 +
|-
 
|Dexion
 
|Dexion
−
|-
 
 
|Dexmene
 
|Dexmene
 
|Dexmesone
 
|Dexmesone
Line 399: Line 307:
 
|Dexmethasone
 
|Dexmethasone
 
|Dexmethsone
 
|Dexmethsone
−
|D E X Nitto Medic
 
 
|Dexona
 
|Dexona
 
|Dexone
 
|Dexone
Line 408: Line 315:
 
|Dexsol
 
|Dexsol
 
|Dexstar
 
|Dexstar
−
|D E X Taiyo
 
 
|Dextason
 
|Dextason
−
|D E X T Galen
 
−
|-
 
 
|Dexthasol
 
|Dexthasol
−
|D E X T Nichiiko
 
 
|Dexton
 
|Dexton
 +
|-
 
|Dextrasone
 
|Dextrasone
 
|Dicorsone
 
|Dicorsone
Line 420: Line 324:
 
|Diometa
 
|Diometa
 
|Dison
 
|Dison
−
|-
+
|DM Solone
−
|DM Solone Nitten
 
−
|DM Solone Sato
 
−
|DOM-Dexamethasone
 
 
|Donray
 
|Donray
 
|Dorison
 
|Dorison
 +
|-
 
|Doronil
 
|Doronil
 
|Drenex
 
|Drenex
 
|Drxaline
 
|Drxaline
−
|-
 
 
|Elixirmethasone
 
|Elixirmethasone
 
|Epidexone
 
|Epidexone
Line 435: Line 336:
 
|Erladexone
 
|Erladexone
 
|Ermethasone
 
|Ermethasone
 +
|-
 
|ETA Cortilen
 
|ETA Cortilen
 
|Etason
 
|Etason
 
|Euromethasone
 
|Euromethasone
−
|-
 
 
|Fada Dexametasona
 
|Fada Dexametasona
 
|Fadametasona
 
|Fadametasona
Line 444: Line 345:
 
|Fexadron
 
|Fexadron
 
|Fortecortin
 
|Fortecortin
−
|Fortecortin-Mono
+
|-
 
|Fosfato Dissodico Dexametasona
 
|Fosfato Dissodico Dexametasona
 
|Gammacorten
 
|Gammacorten
−
|-
 
 
|Gemisona
 
|Gemisona
 
|Glymesason
 
|Glymesason
Line 453: Line 353:
 
|Hexadecadrol
 
|Hexadecadrol
 
|Hexadrol
 
|Hexadrol
−
|Hexadrol Phosphate
 
 
|HI-Methasone
 
|HI-Methasone
 +
|-
 
|Hopamethasone
 
|Hopamethasone
−
|-
 
 
|Idizone
 
|Idizone
 
|Indexon
 
|Indexon
Line 462: Line 361:
 
|Irzamethazone
 
|Irzamethazone
 
|Isodexam
 
|Isodexam
−
|Isopto DEX
+
|Isopto
−
|Isopto Maxidex
+
|Kaarmepakkaus
−
|Isopto Maxidex D
 
 
|-
 
|-
−
|Kaarmepakkaus
 
 
|Kalmethasone
 
|Kalmethasone
 
|Kanadex
 
|Kanadex
Line 474: Line 371:
 
|Lanadexon
 
|Lanadexon
 
|Licoson
 
|Licoson
 +
|Limethason
 
|-
 
|-
−
|Limethason
 
−
|Limethason GC
 
 
|Lipotalon
 
|Lipotalon
 
|Lisoderme
 
|Lisoderme
Line 483: Line 379:
 
|Lokalison-F
 
|Lokalison-F
 
|Lormine
 
|Lormine
−
|-
 
 
|Loverine
 
|Loverine
 
|Lupidexa
 
|Lupidexa
 +
|-
 
|Luxazone
 
|Luxazone
 
|Maradex
 
|Maradex
−
|Maxidex Ophthalmic
+
|Maxidex
 
|Mecoxon
 
|Mecoxon
 
|Medesone
 
|Medesone
 
|Medexasone
 
|Medexasone
−
|-
 
 
|Mediamethasone
 
|Mediamethasone
 
|Medicort
 
|Medicort
 +
|-
 
|Medidex
 
|Medidex
 
|Megacort
 
|Megacort
Line 501: Line 397:
 
|Mephamesona
 
|Mephamesona
 
|Mephamesone
 
|Mephamesone
−
|-
 
 
|Mephamesone-4
 
|Mephamesone-4
 
|Meradexon
 
|Meradexon
 +
|-
 
|Merideca
 
|Merideca
−
|Mesadoron Kobayashi Kako
+
|Mesadoron
−
|Mesadoron Nichiiko
 
 
|Metalexina
 
|Metalexina
 
|Metasolon
 
|Metasolon
 
|Metax
 
|Metax
−
|-
 
 
|Metaxon
 
|Metaxon
 
|Metcort
 
|Metcort
 
|Methaderm
 
|Methaderm
 +
|-
 
|Methasone
 
|Methasone
 
|Mexasone
 
|Mexasone
 
|Mexaton
 
|Mexaton
−
|Micro-Dexamethason
 
 
|Migradexan
 
|Migradexan
−
|-
 
 
|Millicorten
 
|Millicorten
 
|Minidex
 
|Minidex
−
|Minims Dexamethasone
 
 
|Mitasone
 
|Mitasone
 
|Molacort
 
|Molacort
−
|Monofree Dexamethason
+
|-
 
|Mycidex
 
|Mycidex
 
|Neodex
 
|Neodex
−
|-
 
 
|Nexadron
 
|Nexadron
−
|Nexadron Oftal
 
 
|Nodevex
 
|Nodevex
 
|Nufadex M
 
|Nufadex M
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|Ocudex
 
|Ocudex
 
|Oftadek
 
|Oftadek
 +
|-
 
|Oftadex
 
|Oftadex
−
|-
 
−
|Oftan Dexa
 
−
|Oftan Dexamethason
 
 
|Omedexon
 
|Omedexon
 
|Onadron
 
|Onadron
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|Opticort
 
|Opticort
 
|Orazone
 
|Orazone
 +
|Ordex
 
|-
 
|-
−
|Ordex
 
 
|Orgadrone
 
|Orgadrone
−
|Pabi-Dexamethason
 
 
|Penatone
 
|Penatone
 
|Penodex
 
|Penodex
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|Pidexon
 
|Pidexon
 
|Plavex
 
|Plavex
−
|-
 
 
|Plidexa
 
|Plidexa
−
|PMS-Dexamethasone
 
 
|Prodexon
 
|Prodexon
 +
|-
 
|Pyderma
 
|Pyderma
 
|Pyradexon
 
|Pyradexon
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|Randexa
 
|Randexa
 
|Redexon
 
|Redexon
−
|-
 
 
|Rednisone
 
|Rednisone
 
|Reusan
 
|Reusan
 
|Rocolone
 
|Rocolone
 +
|-
 
|Ronic
 
|Ronic
 
|Roximeth
 
|Roximeth
 
|Rupedex
 
|Rupedex
−
|SAB-Opticort
 
−
|Sandoz Dexamethasone
 
−
|-
 
 
|Santeson
 
|Santeson
 
|Sawasone
 
|Sawasone
Line 579: Line 462:
 
|Selftison
 
|Selftison
 
|Shirodex
 
|Shirodex
 +
|-
 
|Shuayan
 
|Shuayan
 
|Smile
 
|Smile
 
|Solcort
 
|Solcort
−
|-
 
 
|Soldesam
 
|Soldesam
−
|Soldesam Pomata
 
 
|Soldesanil
 
|Soldesanil
 
|Soldex
 
|Soldex
 
|Soludecadron
 
|Soludecadron
 
|Solupen
 
|Solupen
−
|Solupen N
 
−
|Solutio Cordes Dexa N
 
 
|-
 
|-
 
|Sonexa
 
|Sonexa
Line 622: Line 502:
 
|Unidexa
 
|Unidexa
 
|Unisone
 
|Unisone
−
|UTO Dexamethasone
 
−
|Vero Dexamethasone
 
 
|Visualin
 
|Visualin
 
|Visumetazone
 
|Visumetazone
 
|Voalla
 
|Voalla
−
|-
 
 
|Windex
 
|Windex
 
|Wymesone
 
|Wymesone
 +
|-
 
|Xasone
 
|Xasone
 
|Xine
 
|Xine
−
|YI KE TIE
 
 
|Zalucs
 
|Zalucs
 
|Zecaxon
 
|Zecaxon
 
|Zenos
 
|Zenos
 +
|Zydexa
 +
|Baycadron
 +
|ZoDex
 
|-
 
|-
−
|Zydexa
+
|Neofordex
 +
|LenaDex
 
|}
 
|}
  
Line 643: Line 524:
 
<references/>
 
<references/>
  
−
[[Category:Drug index]]
+
[[Category:Drugs]]
−
[[Category:Immunosuppresants]]
+
[[Category:Intramuscular medications]]
 +
[[Category:Intravenous medications]]
 +
[[Category:Oral medications]]
 
[[Category:Steroids]]
 
[[Category:Steroids]]
  
−
[[Category:Acute lymphocytic leukemia medications]]
 
 
[[Category:Anaplastic large cell lymphoma medications]]
 
[[Category:Anaplastic large cell lymphoma medications]]
 +
[[Category:B-cell acute lymphoblastic leukemia medications]]
 
[[Category:Burkitt lymphoma medications]]
 
[[Category:Burkitt lymphoma medications]]
 +
[[Category:CNS lymphoma medications]]
 
[[Category:Diffuse large B-cell lymphoma medications]]
 
[[Category:Diffuse large B-cell lymphoma medications]]
−
[[Category:Extranodal NK/T-cell lymphoma, nasal type medications]]
+
[[Category:Extranodal NK- and T-cell lymphoma, nasal type medications]]
 
[[Category:Follicular lymphoma medications]]
 
[[Category:Follicular lymphoma medications]]
 
[[Category:Hemophagocytic lymphohistiocytosis medications]]
 
[[Category:Hemophagocytic lymphohistiocytosis medications]]
 
[[Category:HIV-associated lymphoma medications]]
 
[[Category:HIV-associated lymphoma medications]]
−
[[Category:Hodgkin lymphoma medications]]
+
[[Category:Classical Hodgkin lymphoma medications]]
−
[[Category:Immune thrombocytopenic purpura (ITP) medications]]
+
[[Category:Immune thrombocytopenia medications]]
 
[[Category:Light-chain (AL) amyloidosis medications]]
 
[[Category:Light-chain (AL) amyloidosis medications]]
 
[[Category:Mantle cell lymphoma medications]]
 
[[Category:Mantle cell lymphoma medications]]
−
[[Category:Mast cell diseases medications]]
 
 
[[Category:Multiple myeloma medications]]
 
[[Category:Multiple myeloma medications]]
−
[[Category:NK/T-cell lymphoma medications]]
+
[[Category:NK- and T-cell lymphoma medications]]
 
[[Category:Peripheral T-cell lymphoma medications]]
 
[[Category:Peripheral T-cell lymphoma medications]]
 +
[[Category:Plasma cell leukemia medications]]
 +
[[Category:POEMS syndrome medications]]
 
[[Category:Primary mediastinal B-cell lymphoma medications]]
 
[[Category:Primary mediastinal B-cell lymphoma medications]]
 +
[[Category:Smoldering multiple myeloma medications]]
 +
[[Category:T-cell acute lymphoblastic leukemia medications]]
 
[[Category:Transformed lymphoma medications]]
 
[[Category:Transformed lymphoma medications]]
 
[[Category:Waldenström macroglobulinemia medications]]
 
[[Category:Waldenström macroglobulinemia medications]]
  
−
[[Category:Drugs FDA approved in 1958]]
+
[[Category:Acute myeloid leukemia medications (historic)]]
 +
[[Category:Prostate cancer medications (historic)]]
 +
 
 +
[[Category:FDA approved in 1958]]
 +
[[Category:EMA approved in 1952]]
 +
[[Category:WHO Essential Cancer Medicine]]
 +
[[Category:WHO Essential Pain and Palliative Care Medicine]]

Revision as of 23:48, 2 September 2023

General information

Class/mechanism: Corticosteroid & glucocorticoid which has numerous physiologic effects, including immune system modulation, antiemetic properties, and anti-inflammatory effects.[1][2]
Route: PO, IV, IM
Extravasation: no information

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is established (work in progress)

Diseases for which it is used

Diseases for which it was used

Patient drug information

History of changes in EMA indication

  • 1952-01-01: EURD

History of changes in PMDA indication

Also known as

  • Generic names: dexamethasone acetate, dexamethasone sodium, dexamethasone sodium metasulfobenzoate, dexamethasone sodium phosphate, dexamethasone sodium succinate, dexamethasone sodium sulfate
  • Brand names:
Synonyms
Aacidexam Acetato DE Dexametasona Acetazona Acolon Adrecort Adrekon Aeroseb-DEX Afpred Forte-Dexa
AK-DEX Aldron Alfalyl Alpermell Amumetazon Anemul Aphtasolon Apidex
Arcodexan Auxiloson Auxison Auxisone B Dexzol Bexine Beyonas Dexa Bisuo DS
Brulin Bucokon Bufadexon Butiol Canalon Carbidu Carulon Cebedex
Cellacort Celudex Cetadexon Colircusi Dexametasona Corodex Corson Corsona Corsone
Corsum Corticoidex Cortidax Cortidex Cortidexason Cortitop Coyensu D-Cort
Dacrosone Daidoron Dalalone Danason Danasone Daxilone Decacin Decaderm
Decadolone Decadran Decadron Decadronal Decadronfosfat Deca Forte Decafos Decalin
Decalon Decalona Decan Decans Decaron Decason Decasone Decaspray
Decazol Decdak Decdan Decicort Decilone Decobel Decolite Decone
Decordex Decorex Decoron Decorten Dectan Dectancyl Deexa Deflaren
Dekesu Dekisachosei Dekort Deksa Deksalon Deksamet Dellamethasone Deltafluorene
Demasone Demeson Dermadex Dermidron Deronil Deron S Derson Dersone
Desalark Desametasone Fosf Desason Deson Detametazon Detasone Dethamedin Dexa
Dexabene Dexabeta Dexacen-4 Dexacilin Dexacip Dexa Clinit Dexacollyre Dexacom
Dexacort Dexacortal Dexacortin Dexacortisone Dexacortisyl Dexacotsil Dexacron Dexacutis
Dexaden Dexaderm Dexaderme Dexadermil Dexadon Dexadrol Dexadron Dexaedo
Dexafar Dexafarm Dexaflam Dexaflan Dexagalen Dexagee Dexagel Dexagenta
Dexaglos Dexagreen Dexagrin Dexahexal Dexaleniens Dexalocal Dexaltin Dexam
Dexamag Dexamark Dexame Dexamecortin Dexamedis Dexamedix Dexamedron Dexameral
Dexameson Dexamesone Dexamet Dexametason Dexametasona Dexametax Dexametazon Dexametazona
Dexameth Dexamethason Dexamethasonum Dexamethazon Dexamethazone Dexametin Dexametisona Dexametonal
Dexametrat Dexamex Dexamil Dexamine Dexaminor Dexamo Dexamonozon N Dexanel
Dexan Dexanil Dexano Dexaphos Dexapolcort Dexapro Dexaril Dexaroid
Dexaron Dexart Dexasin Dexasine Dexasol Dexasolone Dexason Dexasone
Dexasonlin Dexatab Dexaton Dexatop Dexatotal Dexaval Dexaven Dexavet
Dexawal Dexawieb Dexazen Dexazona Dexazone Dexicorta Dexin Dexinga
Dexion Dexmene Dexmesone Dexmetha Dexmethasone Dexmethsone Dexona Dexone
Dexonium Dexoptic Dexpak Dexsol Dexstar Dextason Dexthasol Dexton
Dextrasone Dicorsone Dicosheun Diometa Dison DM Solone Donray Dorison
Doronil Drenex Drxaline Elixirmethasone Epidexone Epidrone Erladexone Ermethasone
ETA Cortilen Etason Euromethasone Fada Dexametasona Fadametasona Faridexon Fexadron Fortecortin
Fosfato Dissodico Dexametasona Gammacorten Gemisona Glymesason Grathazon Hexadecadrol Hexadrol HI-Methasone
Hopamethasone Idizone Indexon Inthesa-5 Irzamethazone Isodexam Isopto Kaarmepakkaus
Kalmethasone Kanadex Kodolo Kosa Kovintong Lanadexon Licoson Limethason
Lipotalon Lisoderme Lodex Lodexa Lokalison-F Lormine Loverine Lupidexa
Luxazone Maradex Maxidex Mecoxon Medesone Medexasone Mediamethasone Medicort
Medidex Megacort Megadex Mephameson Mephamesona Mephamesone Mephamesone-4 Meradexon
Merideca Mesadoron Metalexina Metasolon Metax Metaxon Metcort Methaderm
Methasone Mexasone Mexaton Migradexan Millicorten Minidex Mitasone Molacort
Mycidex Neodex Nexadron Nodevex Nufadex M Ocedran Ocudex Oftadek
Oftadex Omedexon Onadron Ophth-DEX Ophthasona Opticort Orazone Ordex
Orgadrone Penatone Penodex Phenodex Pidexon Plavex Plidexa Prodexon
Pyderma Pyradexon Rally-A Randexa Redexon Rednisone Reusan Rocolone
Ronic Roximeth Rupedex Santeson Sawasone Scandexon Selftison Shirodex
Shuayan Smile Solcort Soldesam Soldesanil Soldex Soludecadron Solupen
Sonexa SP Cordexa Spersadex Spondy-Dexa Stedex Steralol Sterasone Steron
Superprednol Supertendin-Depot N Suprason Surodex Sydencort Syndexa Tavesona Teanlang
Teikason Nidek Tekuron Thilodex Thilodexine Totocortin Tuttozem N Ucalon Udicort
Unidex Unidexa Unisone Visualin Visumetazone Voalla Windex Wymesone
Xasone Xine Zalucs Zecaxon Zenos Zydexa Baycadron ZoDex
Neofordex LenaDex

References

  1. ↑ 1.0 1.1 1.2 Dexamethasone (Decadron) package insert
  2. ↑ Dexamethasone (Decadron) package insert (locally hosted backup)
  3. ↑ Dexamethasone (Decadron) patient drug information (Chemocare)
  4. ↑ Dexamethasone (Decadron) patient drug information (UpToDate)
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