Testicular cancer - null regimens

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The purpose of this page is to provide references to "null therapy" such as placebo and observation. These references provide further insight into the historical development of the treatment landscape. See the main testicular cancer page for regimens that include active anticancer treatment.


Adjuvant therapy for resectable disease

Observation

Regimen

Study Dates of enrollment Evidence Comparator Comparative Efficacy
Williams et al. 1987 1979-1984 Phase 3 (C) 1a. BVP
1b. VAB-6
Inferior RFS

Preceding treatment

References

  1. Williams SD, Stablein DM, Einhorn LH, Muggia FM, Weiss RB, Donohue JP, Paulson DF, Brunner KW, Jacobs EM, Spaulding JT, DeWys WD, Crawford ED. Immediate adjuvant chemotherapy versus observation with treatment at relapse in pathological stage II testicular cancer. N Engl J Med. 1987 Dec 3;317(23):1433-8. link to original article PubMed