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Andrew J. Cowan, MD
Seattle, WA


POEMS: Peripheral neuropathy, Organomegaly, Endocrinopathy, Monoclonal plasma cell disorder, and Skin changes

1 regimens on this page
1 variants on this page



All lines of therapy


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RD: Revlimid (Lenalidomide) & Dexamethasone


Study Evidence
Nozza et al. 2017 Phase II, <20 pts


Supportive medications

Monthly cycles, continued until progression or excess toxicity


  1. Nozza A, Terenghi F, Gallia F, Adami F, Briani C, Merlini G, Giordano L, Santoro A, Nobile-Orazio E. Lenalidomide and dexamethasone in patients with POEMS syndrome: results of a prospective, open-label trial. Br J Haematol. 2017 Dec;179(5):748-755. Epub 2017 Oct 19. link to original article contains verified protocol PubMed