Juvenile myelomonocytic leukemia

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David Noyd, MD, MPH
University of Oklahoma
Oklahoma City, OK
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First-line therapy

Azacitidine monotherapy

Regimen

Study Years of enrollment Evidence
Niemeyer et al. 2021 (AZA-JMML-001) 2015-2017 Phase 2, <20 pts (RT)

Chemotherapy

28-day cycles

References

  1. AZA-JMML-001: Niemeyer CM, Flotho C, Lipka DB, Starý J, Rössig C, Baruchel A, Klingebiel T, Micalizzi C, Michel G, Nysom K, Rives S, Schmugge Liner M, Zecca M, Schönung M, Baumann I, Nöllke P, Benettaib B, Biserna N, Poon J, Simcock M, Patturajan M, Menezes D, Gaudy A, van den Heuvel-Eibrink MM, Locatelli F. Response to upfront azacitidine in juvenile myelomonocytic leukemia in the AZA-JMML-001 trial. Blood Adv. 2021 Jul 27;5(14):2901-2908. link to original article link to PMC article PubMed NCT02447666