Difference between revisions of "Vincristine (Oncovin)"

Revision as of 04:00, 12 November 2014

General information

Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.^[1]^[2]
Route: IV
Extravasation: vesicant

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.^[1]

Diseases for which it is used

Patient drug information

History of changes in FDA indication

7/10/1963: Initial FDA approval

Also known as

Precise Name: vinCRIStine Sulfate (RXCUI 11203)

Synonyms
Alcrist	Biocrist	Biocrystin	Cellcristin	Citomid	Citomid RU	Crivosin	Cytomid
Farmistin CS	Fauldvincri	Krebin	Kyocristine	Nevexitin	Oncocristin AQ	Oncovin ELI Lilly	Oncovin INJ.LSG.
Oncovin Yamakawa	Onkocristin	P&U Vincristine	Pericristine	Pharmacristine	Tecnocris	Trav Vincristine	Vero Vincristin
Vincasar	Vincasar PFS	Vinces	Vincosid	Vincran	Vincrex	Vincrifil	Vincrin
Vincrisin	Vincrisol	Vincristin	Vincristina	Vincristina Faulding	Vincristina Filaxis	Vincristina Martian	Vincristin Biosyn
Vincristin CS	Vincristine	Vincristine Abic	Vincristine Comp	Vincristine DBL	Vincristine Lederle	Vincristine Mayne	Vincristine Mayne Pharma ( BEN )
Vincristine Pharmachemie	Vincristinesulfaat	Vincristine Sulfate	Vincristine Sulfate Synthelabo	Vincristine Sulp	Vincristine Sulphate	Vincristine Teva	Vincristinsulfat
Vincristin Sulfate	Vincristinum	Vincrisul	Vinracin	Vinracine	Vinstin	Vintec

References

[insert-1] 1.0 ^1.1 Vincristine (Oncovin) package insert

[2] Vincristine (Oncovin) package insert (locally hosted backup)

[3] Vincristine (Oncovin) patient drug information (Chemocare)

[4] Vincristine (Oncovin) patient drug information (UpToDate)

[1]

[2]

[3]

[4]

@@ Line 18: / Line 18: @@
 *[[Hodgkin lymphoma, nodular lymphocyte-predominant]]
 *[[Mantle cell lymphoma]]
+*[[Marginal zone lymphoma]]
 *[[Multiple myeloma]]
 *[[Neuroendocrine tumors]]
@@ Line 116: / Line 117: @@
 [[Category:Drug index]]
 [[Category:Chemotherapy]]
+[[Category:Vesicant chemotherapy]]
 [[Category:Microtubule inhibitors]]
 [[Category:Vinca alkaloids]]
@@ Line 131: / Line 132: @@
 [[Category:Hodgkin lymphoma, nodular lymphocyte-predominant medications]]
 [[Category:Mantle cell lymphoma medications]]
+[[Category:Marginal zone lymphoma medications]]
 [[Category:Multiple myeloma medications]]
 [[Category:Neuroendocrine tumor medications]]