Semustine (MeCCNU)
General information
Class/mechanism: Nitrosourea, alkylates DNA and RNA and may inhibit certain key enzymatic reactions by carbamoylation of amino acids in proteins. Very similar to lomustine, with a methyl group added.
Route: PO
Extravasation: n/a
Diseases for which it was used
Also known as
- Generic names: MeCCNU, methyl-CCNU, methyl-lomustine
- Brand names: Semustina