Difference between revisions of "CNS carcinoma"

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'''Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any article published 5+ years ago to be for historical purposes, only.'''
 
==[http://www.asco.org/ ASCO]==
 
==[http://www.asco.org/ ASCO]==
 
*'''2022:''' Schiff et al. [https://doi.org/10.1200/jco.22.00333 Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline] [https://www.ncbi.nlm.nih.gov/pubmed/35561283 PubMed]
 
*'''2022:''' Schiff et al. [https://doi.org/10.1200/jco.22.00333 Radiation Therapy for Brain Metastases: ASCO Guideline Endorsement of ASTRO Guideline] [https://www.ncbi.nlm.nih.gov/pubmed/35561283 PubMed]

Revision as of 19:09, 17 October 2023

Section editor
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Seema Nagpal, MD
Stanford University
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This page has regimens and guidelines that are not specific to any one type of cancer. For disease-specific regimens and guidelines, please go to the following pages:

1 regimens on this page
1 variants on this page


Guidelines

Given the rapid change in evidence in many areas of hematology/oncology, readers are encouraged to consider any article published 5+ years ago to be for historical purposes, only.

ASCO

ASCO/SNO/ASTRO

EANO/ESMO

NCCN

All lines of therapy

Whole brain irradiation

WBRT: Whole-Brain Radiation Therapy

Regimen

Study Dates of enrollment Evidence Comparator Comparative Efficacy
Knisely et al. 2007 (RTOG 0118) 2002-2004 Phase 3 (C) Thalidomide & WBRT Did not meet primary endpoint of OS

Radiotherapy

One course

References

  1. RTOG 0118: Knisely JP, Berkey B, Chakravarti A, Yung AW, Curran WJ Jr, Robins HI, Movsas B, Brachman DG, Henderson RH, Mehta MP. A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118). Int J Radiat Oncol Biol Phys. 2008 May 1;71(1):79-86. Epub 2007 Dec 31. link to original article contains dosing details in abstract PubMed NCT00033254