Difference between revisions of "Vincristine (Oncovin)"

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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>  
 
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer.  Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref>  
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==Patient drug information==
 
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*[http://chemocare.com/bio/vincristine.asp Vincristine (Oncovin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/vincristine.asp Vincristine (Oncovin) patient drug information (Chemocare)]</ref>
 
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*[http://www.uptodate.com/contents/vincristine-patient-drug-information Vincristine (Oncovin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/vincristine-patient-drug-information Vincristine (Oncovin) patient drug information (UpToDate)]</ref>
 
  
 
==Diseases for which it is used==
 
==Diseases for which it is used==
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*[[Central nervous system (CNS) cancer]]
 
*[[Central nervous system (CNS) cancer]]
 
*[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]]
 
*[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]]
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*[[CNS lymphoma]]
 
*[[Follicular lymphoma]]
 
*[[Follicular lymphoma]]
 
*[[HIV-associated lymphoma]]
 
*[[HIV-associated lymphoma]]
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*[[Thymoma]]
 
*[[Thymoma]]
 
*[[Transplant conditioning regimens]]
 
*[[Transplant conditioning regimens]]
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==Patient drug information==
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*[http://chemocare.com/bio/vincristine.asp Vincristine (Oncovin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/vincristine.asp Vincristine (Oncovin) patient drug information (Chemocare)]</ref>
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*[http://www.uptodate.com/contents/vincristine-patient-drug-information Vincristine (Oncovin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/vincristine-patient-drug-information Vincristine (Oncovin) patient drug information (UpToDate)]</ref>
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==History of changes in FDA indication==
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* 7/10/1963: Initial FDA approval
  
 
==Also known as==
 
==Also known as==
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[[Category:Bone cancer medications]]  
 
[[Category:Bone cancer medications]]  
 
[[Category:Central nervous system (CNS) cancer medications]]
 
[[Category:Central nervous system (CNS) cancer medications]]
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[[Category:Central nervous system (CNS) lymphoma medications]]
 
[[Category:Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications]]
 
[[Category:Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications]]
 
[[Category:Follicular lymphoma medications]]
 
[[Category:Follicular lymphoma medications]]
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[[Category:Thymoma medications]]
 
[[Category:Thymoma medications]]
 
[[Category:Transplant medications]]
 
[[Category:Transplant medications]]
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[[Category:Drugs FDA approved in 1963]]

Revision as of 03:53, 11 November 2014

General information

Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.[1][2]
Route: IV
Extravasation: vesicant

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is used

Patient drug information

History of changes in FDA indication

  • 7/10/1963: Initial FDA approval

Also known as

Precise Name: vinCRIStine Sulfate (RXCUI 11203)

Synonyms
Alcrist Biocrist Biocrystin Cellcristin Citomid Citomid RU Crivosin Cytomid
Farmistin CS Fauldvincri Krebin Kyocristine Nevexitin Oncocristin AQ Oncovin ELI Lilly Oncovin INJ.LSG.
Oncovin Yamakawa Onkocristin P&U Vincristine Pericristine Pharmacristine Tecnocris Trav Vincristine Vero Vincristin
Vincasar Vincasar PFS Vinces Vincosid Vincran Vincrex Vincrifil Vincrin
Vincrisin Vincrisol Vincristin Vincristina Vincristina Faulding Vincristina Filaxis Vincristina Martian Vincristin Biosyn
Vincristin CS Vincristine Vincristine Abic Vincristine Comp Vincristine DBL Vincristine Lederle Vincristine Mayne Vincristine Mayne Pharma ( BEN )
Vincristine Pharmachemie Vincristinesulfaat Vincristine Sulfate Vincristine Sulfate Synthelabo Vincristine Sulp Vincristine Sulphate Vincristine Teva Vincristinsulfat
Vincristin Sulfate Vincristinum Vincrisul Vinracin Vinracine Vinstin Vintec

References

  1. ↑ 1.0 1.1 Vincristine (Oncovin) package insert
  2. ↑ Vincristine (Oncovin) package insert (locally hosted backup)
  3. ↑ Vincristine (Oncovin) patient drug information (Chemocare)
  4. ↑ Vincristine (Oncovin) patient drug information (UpToDate)
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