Difference between revisions of "Vincristine (Oncovin)"
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For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
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*[[Central nervous system (CNS) cancer]] | *[[Central nervous system (CNS) cancer]] | ||
*[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]] | *[[Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)]] | ||
+ | *[[CNS lymphoma]] | ||
*[[Follicular lymphoma]] | *[[Follicular lymphoma]] | ||
*[[HIV-associated lymphoma]] | *[[HIV-associated lymphoma]] | ||
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*[[Thymoma]] | *[[Thymoma]] | ||
*[[Transplant conditioning regimens]] | *[[Transplant conditioning regimens]] | ||
+ | |||
+ | ==Patient drug information== | ||
+ | *[http://chemocare.com/bio/vincristine.asp Vincristine (Oncovin) patient drug information (Chemocare)]<ref>[http://chemocare.com/bio/vincristine.asp Vincristine (Oncovin) patient drug information (Chemocare)]</ref> | ||
+ | *[http://www.uptodate.com/contents/vincristine-patient-drug-information Vincristine (Oncovin) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/vincristine-patient-drug-information Vincristine (Oncovin) patient drug information (UpToDate)]</ref> | ||
+ | |||
+ | ==History of changes in FDA indication== | ||
+ | * 7/10/1963: Initial FDA approval | ||
==Also known as== | ==Also known as== | ||
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[[Category:Bone cancer medications]] | [[Category:Bone cancer medications]] | ||
[[Category:Central nervous system (CNS) cancer medications]] | [[Category:Central nervous system (CNS) cancer medications]] | ||
+ | [[Category:Central nervous system (CNS) lymphoma medications]] | ||
[[Category:Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications]] | [[Category:Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications]] | ||
[[Category:Follicular lymphoma medications]] | [[Category:Follicular lymphoma medications]] | ||
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[[Category:Thymoma medications]] | [[Category:Thymoma medications]] | ||
[[Category:Transplant medications]] | [[Category:Transplant medications]] | ||
+ | |||
+ | [[Category:Drugs FDA approved in 1963]] |
Revision as of 03:53, 11 November 2014
General information
Class/mechanism: Vinca alkaloid, inhibits microtubule formation in the mitotic spindle, causing cell cycle arrest in metaphase.[1][2]
Route: IV
Extravasation: vesicant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Acute lymphocytic leukemia
- Aggressive Non-Hodgkin lymphoma
- Bone cancer
- Central nervous system (CNS) cancer
- Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL)
- CNS lymphoma
- Follicular lymphoma
- HIV-associated lymphoma
- Hodgkin lymphoma
- Hodgkin lymphoma, nodular lymphocyte-predominant
- Mantle cell lymphoma
- Multiple myeloma
- Neuroendocrine tumors
- Penile cancer
- Sarcoma
- Small cell lung cancer
- Thymoma
- Transplant conditioning regimens
Patient drug information
- Vincristine (Oncovin) patient drug information (Chemocare)[3]
- Vincristine (Oncovin) patient drug information (UpToDate)[4]
History of changes in FDA indication
- 7/10/1963: Initial FDA approval
Also known as
Precise Name: vinCRIStine Sulfate (RXCUI 11203)
Synonyms | |||||||
---|---|---|---|---|---|---|---|
Alcrist | Biocrist | Biocrystin | Cellcristin | Citomid | Citomid RU | Crivosin | Cytomid |
Farmistin CS | Fauldvincri | Krebin | Kyocristine | Nevexitin | Oncocristin AQ | Oncovin ELI Lilly | Oncovin INJ.LSG. |
Oncovin Yamakawa | Onkocristin | P&U Vincristine | Pericristine | Pharmacristine | Tecnocris | Trav Vincristine | Vero Vincristin |
Vincasar | Vincasar PFS | Vinces | Vincosid | Vincran | Vincrex | Vincrifil | Vincrin |
Vincrisin | Vincrisol | Vincristin | Vincristina | Vincristina Faulding | Vincristina Filaxis | Vincristina Martian | Vincristin Biosyn |
Vincristin CS | Vincristine | Vincristine Abic | Vincristine Comp | Vincristine DBL | Vincristine Lederle | Vincristine Mayne | Vincristine Mayne Pharma ( BEN ) |
Vincristine Pharmachemie | Vincristinesulfaat | Vincristine Sulfate | Vincristine Sulfate Synthelabo | Vincristine Sulp | Vincristine Sulphate | Vincristine Teva | Vincristinsulfat |
Vincristin Sulfate | Vincristinum | Vincrisul | Vinracin | Vinracine | Vinstin | Vintec |
References
Categories:
- Drug index
- Chemotherapy
- Microtubule inhibitors
- Vinca alkaloids
- Acute lymphocytic leukemia medications
- Aggressive Non-Hodgkin lymphoma medications
- Bone cancer medications
- Central nervous system (CNS) cancer medications
- Central nervous system (CNS) lymphoma medications
- Chronic lymphocytic leukemia (CLL) and Small lymphocytic lymphoma (SLL) medications
- Follicular lymphoma medications
- HIV-associated lymphoma medications
- Hodgkin lymphoma medications
- Hodgkin lymphoma, nodular lymphocyte-predominant medications
- Mantle cell lymphoma medications
- Multiple myeloma medications
- Neuroendocrine tumor medications
- Penile cancer medications
- Sarcoma medications
- Small cell lung cancer medications
- T-cell lymphoma medications
- Thymoma medications
- Transplant medications
- Drugs FDA approved in 1963