Difference between revisions of "Toremifene (Fareston)"
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==History of changes in FDA indication== | ==History of changes in FDA indication== | ||
| − | * 5/29/1997: Initial FDA approval for the treatment of metastatic [[breast cancer]] in postmenopausal women with [[Biomarkers#ER|estrogen-receptor]] [[Biomarkers#Expression|positive]] or [[Biomarkers#Unknown|unknown]] tumors. | + | * 5/29/1997: Initial FDA approval for the treatment of metastatic [[breast cancer]] in postmenopausal women with [[Biomarkers#ER|estrogen-receptor]] [[Biomarkers#Expression|positive]] or [[Biomarkers#Unknown|unknown]] tumors. ''(Based on Gershanovich et al. 1997, Hayes et al. 1995, Pyrhönen et al. 1997)'' |
==Also known as== | ==Also known as== | ||
Revision as of 23:56, 12 June 2022
General information
Class/mechanism: SERM (selective estrogen receptor modulator), with estrogen agonist/antagonist properties depending on tissue type.[1][2][3]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Toremifene (Fareston) patient drug information (Chemocare)[4]
- Toremifene (Fareston) patient drug information (UpToDate)[5]
History of changes in FDA indication
- 5/29/1997: Initial FDA approval for the treatment of metastatic breast cancer in postmenopausal women with estrogen-receptor positive or unknown tumors. (Based on Gershanovich et al. 1997, Hayes et al. 1995, Pyrhönen et al. 1997)
Also known as
- Brand names: Acapodene, Fareston, Farestone