Difference between revisions of "Anastrozole (Arimidex)"
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==General information== | ==General information== | ||
− | Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[ | + | Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.<ref name="insert">[https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acbfaaa9-503c-4691-9828-76a7146ed6de Anastrozole (Arimidex) package insert]</ref><ref>[[Media:Anastrozole.pdf | Anastrozole (Arimidex) package insert (locally hosted backup)]]</ref><ref>[http://www.arimidex.com/ Arimidex manufacturer's website]</ref> |
<br>Route: PO | <br>Route: PO | ||
<br>Extravasation: n/a | <br>Extravasation: n/a | ||
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==Patient drug information== | ==Patient drug information== | ||
− | *[ | + | *[https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=acbfaaa9-503c-4691-9828-76a7146ed6de Anastrozole (Arimidex) package insert]<ref name="insert"></ref> |
*[http://chemocare.com/chemotherapy/drug-info/anastrozole.aspx Anastrozole (Arimidex) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/anastrozole.aspx Anastrozole (Arimidex) patient drug information (Chemocare)]</ref> | *[http://chemocare.com/chemotherapy/drug-info/anastrozole.aspx Anastrozole (Arimidex) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/anastrozole.aspx Anastrozole (Arimidex) patient drug information (Chemocare)]</ref> | ||
*[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/anastrozole-patient-drug-information Anastrozole (Arimidex) patient drug information (UpToDate)]</ref> |
Revision as of 02:32, 18 May 2019
General information
Class/mechanism: Selective non-steroidal aromatase inhibitor. The aromatase enzyme converts adrenal and ovarian androgens (androstenedione and testosterone) to estrogens (estrone and estradiol) in peripheral tissues.[1][2][3]
Route: PO
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
Patient drug information
- Anastrozole (Arimidex) package insert[1]
- Anastrozole (Arimidex) patient drug information (Chemocare)[4]
- Anastrozole (Arimidex) patient drug information (UpToDate)[5]
History of changes in FDA indication
- 12/27/1995: Initial FDA approval
Also known as
- Brand names: Altraz, Anabrez, Anastraze, Anastrazol Rontag, Anastrol, Arimidex, Asiolex, Karomex, Leprofen, RUI SI YI, RUI Ting, Trozolet, Trozolite.