Difference between revisions of "Thrombocytopenia and platelet dysfunction"

Revision as of 11:35, 15 May 2024

Platelet count less than 150 × 10⁹/L or less than the lower limit of normal as defined by a local laboratory.

May consist of:

CBC with differential
Comprehensive metabolic panel, including liver function tests (LFTs)
Vitamin B12
Folate
Assessment for liver disease, hepatomegaly, fatty liver, splenomegaly
Peripheral smear, platelet clumps
Clinical history (bleeding, temporality, recent infections), TTP/aHUS
Thrombotic history (e.g., heparin/HIT)
Lifestyle factors (e.g. alcohol)
Medications
Hepatitis serologies
HIV
ANA, lupus
Pseudothrombocytopenia, EDTA-induced clumping (draw sample in blue top citrate tube)
Pregnancy/gestational thrombocytopenia
ITP

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