Difference between revisions of "BCG vaccine"
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==Diseases for which it is used== | ==Diseases for which it is used== | ||
*[[Bladder cancer]] (intravesicular use) | *[[Bladder cancer]] (intravesicular use) | ||
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| + | ==Diseases for which it was used== | ||
| + | *[[B-cell acute lymphoblastic leukemia - historical|B-cell acute lymphoblastic leukemia]] | ||
| + | *[[Breast cancer - historical|Breast cancer]] | ||
| + | *[[Colon cancer - historical|Colon cancer]] | ||
| + | *[[Diffuse large B-cell lymphoma - historical|Diffuse large B-cell lymphoma]] | ||
| + | *[[Hodgkin lymphoma - historical|Hodgkin lymphoma]] | ||
| + | *[[Melanoma - historical|Melanoma]] | ||
| + | *[[Non-small cell lung cancer - historical|Non-small cell lung cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
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[[Category:Bladder cancer medications]] | [[Category:Bladder cancer medications]] | ||
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| + | *[[Category:B-cell acute lymphoblastic leukemia medications (historic)]] | ||
| + | *[[Category:Breast cancer medications (historic)]] | ||
| + | *[[Category:Colon cancer medications (historic)]] | ||
| + | *[[Category:Diffuse large B-cell lymphoma medications (historic)]] | ||
| + | *[[Category:Hodgkin lymphoma medications (historic)]] | ||
| + | *[[Category:Melanoma medications (historic)]] | ||
| + | *[[Category:Non-small cell lung cancer medications (historic)]] | ||
[[Category:FDA approved drugs]] | [[Category:FDA approved drugs]] | ||
Revision as of 02:08, 26 April 2022
General information
Class/mechanism: Live mycobacteria which promote a local acute inflammatory and sub-acute granulomatous reaction with macrophage and leukocyte infiltration in the urothelium and lamina propria of the urinary bladder. This results in a likely T-lymphocyte dependent anti-tumor effect.[1][2]
Route: Intravesicular
Extravasation: n/a
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Bladder cancer (intravesicular use)
Diseases for which it was used
- B-cell acute lymphoblastic leukemia
- Breast cancer
- Colon cancer
- Diffuse large B-cell lymphoma
- Hodgkin lymphoma
- Melanoma
- Non-small cell lung cancer
Patient drug information
- Bacillus Calmette-Guérin (BCG) package insert
- Bacillus Calmette-Guérin (BCG) patient drug information (Chemocare)[3]
- Patient information about bladder cancer treatment, including BCG (UpToDate)[4]
Also known as
- Generic name: Bacille Calmette–Guérin
- Brand names: TheraCys, TICE BCG
References
- Drugs
- Intravesical medications
- Immunotherapeutic
- T-cell activators
- Bladder cancer medications
- B-cell acute lymphoblastic leukemia medications (historic)
- Breast cancer medications (historic)
- Colon cancer medications (historic)
- Diffuse large B-cell lymphoma medications (historic)
- Hodgkin lymphoma medications (historic)
- Melanoma medications (historic)
- Non-small cell lung cancer medications (historic)
- FDA approved drugs