Difference between revisions of "Docetaxel (Taxotere)"
Jump to navigation
Jump to search
m (Text replace - "package insert<ref name="insert"></ref>." to "prescribing information.<ref name="insert"></ref>") |
(updated content) |
||
| Line 1: | Line 1: | ||
==General information== | ==General information== | ||
| − | Class/mechanism: Taxane; disrupts normal microtubular function. Binds to free tubulin, promotes their assembly into stable microtubules, and inhibits their disassembly, which inhibits mitosis.<ref name="insert">[http://products.sanofi.us/taxotere/taxotere.pdf Docetaxel (Taxotere) package insert]</ref><ref>[ | + | Class/mechanism: Taxane; disrupts normal microtubular function. Binds to free tubulin, promotes their assembly into stable microtubules, and inhibits their disassembly, which inhibits mitosis.<ref name="insert">[http://products.sanofi.us/taxotere/taxotere.pdf Docetaxel (Taxotere) package insert]</ref><ref>[[Media:Docetaxel.pdf | Docetaxel (Taxotere) package insert (locally hosted backup)]]</ref> |
<br>Route: IV | <br>Route: IV | ||
<br>Extravasation: [[irritant]], rare [[vesicant]] | <br>Extravasation: [[irritant]], rare [[vesicant]] | ||
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as [http://www.thomsonhc.com/home/dispatch Micromedex], [http://online.lexi.com/ Lexicomp], [http://www.utdol.com/online/content/search.do UpToDate (courtesy of Lexicomp)], or the prescribing information.<ref name="insert"></ref> | ||
| + | |||
| + | ==Diseases for which it is used== | ||
| + | *[[Bone cancer]] | ||
| + | *[[Breast cancer]] | ||
| + | *[[Unknown primary|Cancer of unknown primary]] | ||
| + | *[[Cervical cancer]] | ||
| + | *[[Esophageal cancer]] | ||
| + | *[[Non-small cell lung cancer]] | ||
| + | *[[Ovarian cancer]] | ||
| + | *[[Pancreatic cancer]] | ||
| + | *[[Prostate cancer]] | ||
==Patient drug information== | ==Patient drug information== | ||
| − | *[http://chemocare.com/ | + | *[http://chemocare.com/chemotherapy/drug-info/docetaxel.aspx Docetaxel (Taxotere) patient drug information (Chemocare)]<ref>[http://chemocare.com/chemotherapy/drug-info/docetaxel.aspx Docetaxel (Taxotere) patient drug information (Chemocare)]</ref> |
| + | *[http://products.sanofi.us/taxotere/taxotere.pdf#page=16 Docetaxel (Taxotere) package insert pages 16-17]<ref name="insert"></ref> | ||
*[http://www.uptodate.com/contents/docetaxel-patient-drug-information Docetaxel (Taxotere) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/docetaxel-patient-drug-information Docetaxel (Taxotere) patient drug information (UpToDate)]</ref> | *[http://www.uptodate.com/contents/docetaxel-patient-drug-information Docetaxel (Taxotere) patient drug information (UpToDate)]<ref>[http://www.uptodate.com/contents/docetaxel-patient-drug-information Docetaxel (Taxotere) patient drug information (UpToDate)]</ref> | ||
==References== | ==References== | ||
<references/> | <references/> | ||
| + | |||
| + | [[Category:Drug index]] | ||
| + | [[Category:Chemotherapy]] | ||
| + | [[Category:Irritant chemotherapy]] | ||
| + | [[Category:Vesicant chemotherapy]] | ||
| + | [[Category:Taxanes]] | ||
| + | [[Category:Bone cancer medications]] | ||
| + | [[Category:Breast cancer medications]] | ||
| + | [[Category:Cancer of unknown primary medications]] | ||
| + | [[Category:Cervical cancer medications]] | ||
| + | [[Category:Esophageal cancer medications]] | ||
| + | [[Category:Non-small cell lung cancer medications]] | ||
| + | [[Category:Ovarian cancer medications]] | ||
| + | [[Category:Pancreatic cancer medications]] | ||
| + | [[Category:Prostate cancer medications]] | ||
Revision as of 00:29, 15 October 2012
General information
Class/mechanism: Taxane; disrupts normal microtubular function. Binds to free tubulin, promotes their assembly into stable microtubules, and inhibits their disassembly, which inhibits mitosis.[1][2]
Route: IV
Extravasation: irritant, rare vesicant
For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, UpToDate (courtesy of Lexicomp), or the prescribing information.[1]
Diseases for which it is used
- Bone cancer
- Breast cancer
- Cancer of unknown primary
- Cervical cancer
- Esophageal cancer
- Non-small cell lung cancer
- Ovarian cancer
- Pancreatic cancer
- Prostate cancer
Patient drug information
- Docetaxel (Taxotere) patient drug information (Chemocare)[3]
- Docetaxel (Taxotere) package insert pages 16-17[1]
- Docetaxel (Taxotere) patient drug information (UpToDate)[4]
References
Categories:
- Drug index
- Chemotherapy
- Irritant chemotherapy
- Vesicant chemotherapy
- Taxanes
- Bone cancer medications
- Breast cancer medications
- Cancer of unknown primary medications
- Cervical cancer medications
- Esophageal cancer medications
- Non-small cell lung cancer medications
- Ovarian cancer medications
- Pancreatic cancer medications
- Prostate cancer medications