Difference between revisions of "Prostate cancer"
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==Links== | ==Links== | ||
− | [http://urology.jhu.edu/prostate/partintables.php Partin tables] to predict pathologic stage based on clinical TNM stage, PSA, and Gleason score | + | *[http://urology.jhu.edu/prostate/partintables.php Partin tables] to predict pathologic stage based on clinical TNM stage, PSA, and Gleason score |
+ | *[http://www.diagnocure.com/en/products-projects/prostate-cancer/pca3-test-healthcare-practitioners.php PCA3 RNA urine test] | ||
+ | **[http://www.pca3.org/ PCA3.org] |
Revision as of 18:44, 19 April 2012
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Is there a regimen missing from this list? Would you like to share a different dosage/schedule or an additional reference for a regimen? Have you noticed an error? Do you have an idea that will help the site grow to better meet your needs and the needs of many others? You are invited to contribute to the site.
Metastatic castrate-resistant disease
Cabazitaxel (Jevtana)
Regimen
- Cabazitaxel (Jevtana) 25 mg/m2 IV over 1 hour on day 1
- Prednisone (Sterapred) 10 mg PO on days 1-21
21-day cycles x up to 10 cycles
Supportive medications:
- "Antihistamine, corticosteroid (dexamethasone 8 mg or equivalent), and histamine H2-antagonist (except cimetidine)" given at least 30 minutes before cabazitaxel
References
- de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I, Gravis G, Bodrogi I, Mackenzie MJ, Shen L, Roessner M, Gupta S, Sartor AO; TROPIC Investigators. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010 Oct 2;376(9747):1147-54. link to original article contains protocol PubMed
Mitoxantrone (Novantrone)
Regimen
- Mitoxantrone (Novantrone) 12 mg/m2 IV over 15-30 minutes on day 1
- Prednisone (Sterapred) 10 mg PO on days 1-21
21-day cycles x up to 10 cycles
References
- de Bono JS, Oudard S, Ozguroglu M, Hansen S, Machiels JP, Kocak I, Gravis G, Bodrogi I, Mackenzie MJ, Shen L, Roessner M, Gupta S, Sartor AO; TROPIC Investigators. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet. 2010 Oct 2;376(9747):1147-54. link to original article contains protocol PubMed
Links
- Partin tables to predict pathologic stage based on clinical TNM stage, PSA, and Gleason score
- PCA3 RNA urine test