Meningioma

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SeemaNagpal.jpg
Seema Nagpal, MD
Palo Alto, CA
regimens on this page
variants on this page


Guidelines

EANO

NCCN

Unresectable, all lines of therapy

Placebo

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Regimen

Study Evidence Comparator Efficacy
Ji et al. 2015 (SWOG S9005) Phase III (C) Mifepristone Seems not superior

No active antineoplastic treatment.

References

  1. SWOG S9005: Ji Y, Rankin C, Grunberg S, Sherrod AE, Ahmadi J, Townsend JJ, Feun LG, Fredericks RK, Russell CA, Kabbinavar FF, Stelzer KJ, Schott A, Verschraegen C. Double-blind phase III randomized trial of the antiprogestin agent mifepristone in the treatment of unresectable meningioma: SWOG S9005. J Clin Oncol. 2015 Dec 1;33(34):4093-8. Epub 2015 Nov 2. link to original article link to PMC article PubMed