EGFR

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1 regimens on this page
1 variants on this page


Note: this is a new type of page for HemOnc.org, as most other regimen pages are tissue-specific. We will collect published information from basket trials on these pages, as well as regimens that are FDA approved.

All lines of therapy

Erlotinib monotherapy

Regimen

Study Evidence
Hainsworth et al. 2018 (MyPathway) Phase IIa, <20 pts in this arm

Eligibility criteria

  • EGFR nonsynonymous exon 18 or exon 21 mutations, or exon 19 deletions

Chemotherapy

Continued indefinitely

References

  1. MyPathway: Hainsworth JD, Meric-Bernstam F, Swanton C, Hurwitz H, Spigel DR, Sweeney C, Burris H, Bose R, Yoo B, Stein A, Beattie M, Kurzrock R. Targeted therapy for advanced solid tumors on the basis of molecular profiles: results from MyPathway, an open-label, phase IIa multiple basket study. J Clin Oncol. 2018 Feb 20;36(6):536-542. Epub 2018 Jan 10. link to original article contains verified protocol PubMed